Laser Induced, Biologically Engineered Remodeling of Thermally Injured Skin Trial

Beginning
2013
Ending
2017
Legacy
Legacy
Acronym
LIBERTI
Description
The LIBERTI (Laser Induced, Biologically Engineered Remodeling of Thermally Injured) Skin Trial is a SMART (Sequential Multiple Assignment Randomized Trial) design to discover the best sequence of treatments over three time intervals to improve outcomes for patients with severe burn scarring as a function of baseline and historical tailoring variables. In addition, a simple randomized comparison of the three treatments (standard of care plus two different laser treatments) using a surrogate outcome is embedded within the SMART design.
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