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ARIC Publications

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2021
Mok Y, Ballew SH, Stacey RBrandon, et al. "Albuminuria and Prognosis Among Individuals With Atherosclerotic Cardiovascular Disease: The ARIC Study." J Am Coll Cardiol. 2021;78(1):87-89.
Moore CR, Jain S, Haas S, et al. "Ascertaining Framingham heart failure phenotype from inpatient electronic health record data using natural language processing: a multicentre Atherosclerosis Risk in Communities (ARIC) validation study." BMJ Open. 2021;11(6):e047356.
Parikh RR, Folsom AR, Poudel K, et al. "Association of Differential Leukocyte Count With Incident Abdominal Aortic Aneurysm Over 22.5 Years: The ARIC Study." Arterioscler Thromb Vasc Biol. 2021;41(8):2342-2351.
Hyacinth HI, Franceschini N, Seals SR, et al. "Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals." JAMA Netw Open. 2021;4(1):e2030435.
Selvaraj S, Claggett B, Minamisawa M, et al. "Atrial Fibrillation and Ischemic Stroke With the Amyloidogenic V122I Transthyretin Variant Among Black Americans." J Am Coll Cardiol. 2021;78(1):89-91.
Natarajan P, Pampana A, Graham SE, et al. "Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices." Nat Commun. 2021;12(1):2182.
Kou M, Ding N, Ballew SH, et al. "Conventional and Novel Lipid Measures and Risk of Peripheral Artery Disease." Arterioscler Thromb Vasc Biol. 2021;41(3):1229-1238.
Goodrich JK, Singer-Berk M, Son R, et al. "Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes." Nat Commun. 2021;12(1):3505.
Graff M, Justice AE, Young KL, et al. "Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry." Am J Hum Genet. 2021;108(4):564-582.
Johnson JA, Haq KT, Lutz KJ, et al. "Electrophysiological ventricular substrate of stroke: a prospective cohort study in the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open. 2021;11(9):e048542.
Gondalia R, Baldassari A, Holliday KM, et al. "Epigenetically mediated electrocardiographic manifestations of sub-chronic exposures to ambient particulate matter air pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Res. 2021;198:111211.
Thibord F, Song C, Pattee J, et al. FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer.. Vol. 19.; 2021. J Thromb Haemost 19(8).
Rooney MR, Norby FL, Maheshwari A, et al. "Frequent Premature Atrial Contractions Are Associated With Poorer Cognitive Function in the Atherosclerosis Risk in Communities (ARIC) Study." Mayo Clin Proc. 2021;96(5):1147-1156.
Schunk SJ, Kleber ME, März W, et al. "Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality." Eur Heart J. 2021;42(18):1742-1756.
Luo S, Feofanova EV, Tin A, et al. "Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension." Kidney Int. 2021;100(2):430-439.
Jones G, Trajanoska K, Santanasto AJ, et al. "Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
Ebong IA, Wilson MD, Bertoni AG, et al. "High-sensitivity cardiac troponin T and the risk of heart failure in postmenopausal women of the ARIC Study." Menopause. 2021;28(3):284-291.
Narayan KMVenkat, Kondal D, Kobes S, et al. "Incidence of diabetes in South Asian young adults compared to Pima Indians." BMJ Open Diabetes Res Care. 2021;9(1).
Sarnowski C, Cousminer DL, Franceschini N, et al. "Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche." Hum Reprod. 2021;36(7):1999-2010.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Kahali B, Chen Y, Feitosa MF, et al. "A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction." J Clin Endocrinol Metab. 2021;106(2):372-387.
Seplyarskiy VB, Soldatov RA, Koch E, et al. "Population sequencing data reveal a compendium of mutational processes in the human germ line." Science. 2021;373(6558):1030-1035.
Schneider ALC, Wang D, Gottesman RF, Selvin E. "Prevalence of Disability Associated With Head Injury With Loss of Consciousness in Adults in the United States: A Population-Based Study." Neurology. 2021;97(2):e124-e135.
Palta P, A Sharrett R, Gabriel KPettee, et al. "Prospective Analysis of Leisure-Time Physical Activity in Midlife and Beyond and Brain Damage on MRI in Older Adults." Neurology. 2021;96(7):e964-e974.
Honda Y, Mok Y, Mathews L, et al. "Psychosocial factors and subsequent risk of hospitalizations with peripheral artery disease: The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2021;329:36-43.
Griswold ME, Talluri R, Zhu X, et al. "Reflection on modern methods: shared-parameter models for longitudinal studies with missing data." Int J Epidemiol. 2021;50(4):1384-1393.
Caughey MC, Qiao Y, Meyer ML, et al. "Relationship Between Central Artery Stiffness, Brain Arterial Dilation, and White Matter Hyperintensities in Older Adults: The ARIC Study-Brief Report." Arterioscler Thromb Vasc Biol. 2021;41(6):2109-2116.
"SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe." Eur Heart J. 2021;42(25):2439-2454.
"SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions." Eur Heart J. 2021;42(25):2455-2467.
Taliun D, Harris DN, Kessler MD, et al. "Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program." Nature. 2021;590(7845):290-299.
Levine DA, Gross AL, Briceño EM, et al. "Sex Differences in Cognitive Decline Among US Adults." JAMA Netw Open. 2021;4(2):e210169.
Lagou V, Mägi R, Hottenga J-Jan, et al. "Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability." Nat Commun. 2021;12(1):24.
Hussain A, Tang O, Sun C, et al. "Soluble Angiotensin-Converting Enzyme 2, Cardiac Biomarkers, Structure, and Function, and Cardiovascular Events (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2021;146:15-21.
Yu B, Roberts MB, Raffield LM, et al. "Supplemental Association of Clonal Hematopoiesis With Incident Heart Failure." J Am Coll Cardiol. 2021;78(1):42-52.
Lye WKit, Paterson E, Patterson CC, et al. "A systematic review and participant-level meta-analysis found little association of retinal microvascular caliber with reduced kidney function." Kidney Int. 2021;99(3):696-706.
Chen J, Spracklen CN, Marenne G, et al. "The trans-ancestral genomic architecture of glycemic traits." Nat Genet. 2021;53(6):840-860.
2020
Hu EA, Steffen LM, Coresh JJ, Appel LJ. "Adherence to the Healthy Eating Index-2015 and Other Dietary Patterns May Reduce Risk of Cardiovascular Disease, Cardiovascular Mortality, and All-Cause Mortality." J Nutr. 2020;150(2):312-321.
Onyeaghala G, Lintelmann AK, Joshu CE, et al. "Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention guidelines and colorectal cancer incidence among African Americans and whites: The Atherosclerosis Risk in Communities study." Cancer. 2020;126(5):1041-1050.
Beck JD, Philips K, Moss K, Divaris K, Morelli T. "Advances in precision oral health." Periodontol 2000. 2020;82(1):268-285.
Mok Y, Ballew SH, Sang Y, Coresh JJ, Joshu CE, Platz EA. "Albuminuria, Kidney Function, and Cancer Risk in the Community." Am J Epidemiol. 2020;189(9):942-950.
Raffield LM, Iyengar AK, Wang B, et al. "Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts." Am J Hum Genet. 2020;106(1):112-120.
Ding J, Davis-Plourde KL, Sedaghat S, et al. "Antihypertensive medications and risk for incident dementia and Alzheimer's disease: a meta-analysis of individual participant data from prospective cohort studies." Lancet Neurol. 2020;19(1):61-70.
Hao Q, Gottesman RF, Qiao Y, et al. "Association between kidney disease measures and intracranial atherosclerosis: The ARIC study." Neurology. 2020;94(22):e2361-e2372.
Bennett EE, Gianattasio KZ, Hughes TM, Mosley TH, Wong DF, Gottesman RF. "The association between midlife lipid levels and late-life brain amyloid deposition." Neurobiol Aging. 2020;92:73-74.
Gaye B, Tajeu GS, Vasan RS, et al. "Association of Changes in Cardiovascular Health Metrics and Risk of Subsequent Cardiovascular Disease and Mortality." J Am Heart Assoc. 2020;9(19):e017458.
Knol MJ, Lu D, Traylor M, et al. "Association of common genetic variants with brain microbleeds: A genome-wide association study." Neurology. 2020;95(24):e3331-e3343.
Cheng Y-J, Zhao X-X, Pan S-P, Pan J-M, Zhang M, Li Z-Y. "Association of early repolarization pattern with cardiovascular outcomes in middle-aged population: A cohort study." Clin Cardiol. 2020;43(12):1601-1608.
Poon AK, Meyer ML, Tanaka H, et al. "Association of insulin resistance, from mid-life to late-life, with aortic stiffness in late-life: the Atherosclerosis Risk in Communities Study." Cardiovasc Diabetol. 2020;19(1):11.
McEvoy JW, Daya N, Rahman F, et al. "Association of Isolated Diastolic Hypertension as Defined by the 2017 ACC/AHA Blood Pressure Guideline With Incident Cardiovascular Outcomes." JAMA. 2020;323(4):329-338.
Poudel K, Shah AM, Michos ED, Folsom AR, Konety S. "Association of serum calcium and phosphorus with measures of left ventricular structure and function: The ARIC study." Nutr Metab Cardiovasc Dis. 2020;30(5):758-767.
Gellert KS, Alonso A, Chen LYee, Meyer ML, Soliman EZ, Suzuki T. "Association of Sleep Apnea, Diagnosed by Self-Reported Physician Diagnosis or Hospital Discharge Codes, With Atrial Fibrillation and Ectopy Using Ambulatory Electrocardiogram in the ARIC Study." Circ Arrhythm Electrophysiol. 2020;13(4):e007574.
Walker KA, Gottesman RF, Coresh JJ, et al. "Association of Surgical Hospitalization with Brain Amyloid Deposition: The Atherosclerosis Risk in Communities-Positron Emission Tomography (ARIC-PET) Study." Anesthesiology. 2020;132(6):1407-1418.
DeBoer MD, Filipp SL. "Associations of a metabolic syndrome severity score with coronary heart disease and diabetes in fasting vs. non-fasting individuals." Nutr Metab Cardiovasc Dis. 2020;30(1):92-98.
Hicks CW, Wang D, Daya NR, B Windham G, Ballantyne CM, Matsushita K. "Associations of Cardiac, Kidney, and Diabetes Biomarkers With Peripheral Neuropathy among Older Adults in the Atherosclerosis Risk in Communities (ARIC) Study." Clin Chem. 2020;66(5):686-696.
Moazzami K, Shao IYuefan, Chen LYee, et al. "Atrial Fibrillation, Brain Volumes, and Subclinical Cerebrovascular Disease (from the Atherosclerosis Risk in Communities Neurocognitive Study [ARIC-NCS])." Am J Cardiol. 2020;125(2):222-228.
Sargurupremraj M, Suzuki H, Jian X, et al. "Cerebral small vessel disease genomics and its implications across the lifespan." Nat Commun. 2020;11(1):6285.
Alonso A, Rooney MR, Chen LYee, et al. "Circulating electrolytes and the prevalence of atrial fibrillation and supraventricular ectopy: The Atherosclerosis Risk in Communities (ARIC) study." Nutr Metab Cardiovasc Dis. 2020;30(7):1121-1129.
Armstrong NJ, Mather KA, Sargurupremraj M, et al. "Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities." Stroke. 2020;51(7):2111-2121.
Kessler MD, Loesch DP, Perry JA, et al. "De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population." Proc Natl Acad Sci U S A. 2020;117(5):2560-2569.
Gigliotti JC, Tin A, Pourafshar S, et al. " Deletion Exaggerates Kidney Injury in Experimental Mouse Models and Confers the Protective Effect of Cruciferous Vegetables in Mice and Humans." J Am Soc Nephrol. 2020;31(1):102-116.
Li X, Li Z, Zhou H, et al. "Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale." Nat Genet. 2020;52(9):969-983.
Cowan LT, Lakshminarayan K, Lutsey PL, Beck J, Offenbacher S. "Endodontic therapy and incident cardiovascular disease: The Atherosclerosis Risk in Communities (ARIC) study." J Public Health Dent. 2020;80(1):79-91.
Bressler J, Marioni RE, Walker RM, et al. "Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2020;75(3):473-480.
Longchamps RJ, Castellani CA, Yang SY, et al. "Evaluation of mitochondrial DNA copy number estimation techniques." PLoS One. 2020;15(1):e0228166.
Ding N, Yang C, Ballew SH, et al. "Fibrosis and Inflammatory Markers and Long-Term Risk of Peripheral Artery Disease: The ARIC Study." Arterioscler Thromb Vasc Biol. 2020;40(9):2322-2331.
Lin D-Y, Zeng D, Couper D. "A general framework for integrative analysis of incomplete multiomics data." Genet Epidemiol. 2020;44(7):646-664.
Grasby KL, Jahanshad N, Painter JN, et al. "The genetic architecture of the human cerebral cortex." Science. 2020;367(6484).
Hofer E, Roshchupkin GV, Adams HHH, et al. "Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults." Nat Commun. 2020;11(1):4796.
Hahn J, Fu Y-P, Brown MR, et al. "Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium." PLoS One. 2020;15(11):e0230035.
Shah S, Henry A, Roselli C, et al. "Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure." Nat Commun. 2020;11(1):163.
Keene KL, Hyacinth HI, Bis JC, et al. "Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke." Stroke. 2020;51(8):2454-2463.
Fanola CL, Norby FL, Shah AM, et al. "Incident Heart Failure and Long-Term Risk for Venous Thromboembolism." J Am Coll Cardiol. 2020;75(2):148-158.
Ishigami J, Cowan LT, Demmer RT, et al. "Incident Hospitalization with Major Cardiovascular Diseases and Subsequent Risk of ESKD: Implications for Cardiorenal Syndrome." J Am Soc Nephrol. 2020;31(2):405-414.
Bick AG, Weinstock JS, Nandakumar SK, et al. "Inherited causes of clonal haematopoiesis in 97,691 whole genomes." Nature. 2020;586(7831):763-768.
Poon AK, Whitsel EA, Heiss G, Soliman EZ, Wagenknecht LE, Suzuki T. "Insulin resistance and reduced cardiac autonomic function in older adults: the Atherosclerosis Risk in Communities study." BMC Cardiovasc Disord. 2020;20(1):217.
Gondalia R, Holliday KM, Baldassari A, et al. "Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
George KM, Lutsey PL, Kucharska-Newton AMaria, Palta P, Heiss G, Osypuk T. "Life-Course Individual and Neighborhood Socioeconomic Status and Risk of Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." Am J Epidemiol. 2020;189(10):1134-1142.
Alam AB, Lutsey PL, Gottesman RF, Tin A, Alonso A. "Low Serum Magnesium is Associated with Incident Dementia in the ARIC-NCS Cohort." Nutrients. 2020;12(10).
Oelsner EC, Balte PP, Bhatt SP, et al. "Lung function decline in former smokers and low-intensity current smokers: a secondary data analysis of the NHLBI Pooled Cohorts Study." Lancet Respir Med. 2020;8(1):34-44.

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