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ARIC Publications

Filters: Keyword is Multifactorial Inheritance  [Clear All Filters]
2022
Wainschtein P, Jain D, Zheng Z, et al. "Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data." Nat Genet. 2022;54(3):263-273.
Nauffal V, Morrill VN, Jurgens SJ, et al. "Monogenic and Polygenic Contributions to QTc Prolongation in the Population." Circulation. 2022;145(20):1524-1533.
Hindy G, Dornbos P, Chaffin MD, et al. "Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes." Am J Hum Genet. 2022;109(1):81-96.
2021
Goodrich JK, Singer-Berk M, Son R, et al. "Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes." Nat Commun. 2021;12(1):3505.
Chen J, Spracklen CN, Marenne G, et al. "The trans-ancestral genomic architecture of glycemic traits." Nat Genet. 2021;53(6):840-860.
2020
Ntalla I, Weng L-C, Cartwright JH, et al. "Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction." Nat Commun. 2020;11(1):2542.
2019
Petty LE, Highland HM, Gamazon ER, et al. "Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample." Hum Mol Genet. 2019;28(7):1212-1224.
Wojcik GL, Graff M, Nishimura KK, et al. "Genetic analyses of diverse populations improves discovery for complex traits." Nature. 2019;570(7762):514-518.
2018
Davies G, Lam M, Harris SE, et al. "Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function." Nat Commun. 2018;9(1):2098.
2017
Harris SE, Hagenaars SP, Davies G, et al. "Molecular genetic contributions to self-rated health." Int J Epidemiol. 2017;46(3):994-1009.
Marouli E, Graff M, Medina-Gomez C, et al. "Rare and low-frequency coding variants alter human adult height." Nature. 2017;542(7640):186-190.
Liang J, Le TH, Edwards DRVelez, et al. "Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations." PLoS Genet. 2017;13(5):e1006728.
2016
Marioni RE, Yang J, Dykiert D, et al. "Assessing the genetic overlap between BMI and cognitive function." Mol Psychiatry. 2016;21(10):1477-82.
Khera AV, Emdin CA, Drake I, et al. "Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease." N Engl J Med. 2016;375(24):2349-2358.
2015
Luciano M, Marioni RE, Hernández MValdés, et al. "Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities." Twin Res Hum Genet. 2015;18(6):738-45.
2014
Tabor HK, Auer PL, Jamal SM, et al. "Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results." Am J Hum Genet. 2014;95(2):183-93.
2010
Allen HLango, Estrada K, Lettre G, et al. "Hundreds of variants clustered in genomic loci and biological pathways affect human height." Nature. 2010;467(7317):832-8.