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Filters: Keyword is Proprotein Convertase 9  [Clear All Filters]
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Lange LA, Hu Y, Zhang H, et al. "Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol." Am J Hum Genet. 2014;94(2):233-45.
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Folsom AR, Peacock JM, Boerwinkle E. "Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease." Atherosclerosis. 2009;202(1):211-5.
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Wu Y, Waite LL, Jackson AU, et al. "Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained." PLoS Genet. 2013;9(3):e1003379.
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Cohen JC, Boerwinkle E, Mosley TH, Hobbs HH. "Sequence variations in PCSK9, low LDL, and protection against coronary heart disease." N Engl J Med. 2006;354(12):1264-72.
Folsom AR, Peacock JM, Boerwinkle E. "Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence." Cancer Epidemiol Biomarkers Prev. 2007;16(11):2455-8.
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Khera AV, Won H-H, Peloso GM, et al. "Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia." J Am Coll Cardiol. 2016;67(22):2578-89.
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Peloso GM, Lange LA, Varga TV, et al. "Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study." Circ Cardiovasc Genet. 2016;9(4):368-74.