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ARIC Publications

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2022
Hasbani NR, Ligthart S, Brown MR, et al. "American Heart Association's Life's Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease." Circulation. 2022;145(11):808-818.
Patel AP, Dron JS, Wang M, et al. "Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes and All-Cause Mortality." JAMA Cardiol. 2022;7(7):723-732.
Stone K, Fryer S, Faulkner J, et al. "Associations of lower-limb atherosclerosis and arteriosclerosis with cardiovascular risk factors and disease in older adults: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2022;340:53-60.
Florido R, Daya NR, Ndumele CE, et al. "Cardiovascular Disease Risk Among Cancer Survivors: The Atherosclerosis Risk In Communities (ARIC) Study." J Am Coll Cardiol. 2022;80(1):22-32.
Zeng X, Jiang S, Ruan S, et al. "Cardiovascular risk factors and breast cancer incidence in a large middle-aged cohort study." BMC Cancer. 2022;22(1):534.
Huan T, Nguyen S, Colicino E, et al. "Integrative analysis of clinical and epigenetic biomarkers of mortality." Aging Cell. 2022;21(6):e13608.
Xiao Q, Heiss G, Kucharska-Newton A, Bey G, Love S-AM, Whitsel EA. "Life-Course Neighborhood Socioeconomic Status and Cardiovascular Events in Black and White Adults in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2022;191(8):1470-1484.
Commodore-Mensah Y, Mok Y, Gottesman RF, et al. "Life's Simple 7 at Midlife and Risk of Recurrent Cardiovascular Disease and Mortality after Stroke: The ARIC study." J Stroke Cerebrovasc Dis. 2022;31(7):106486.
Ma Y, Floyd JS, Austin TR, et al. "Life's Simple 7 Cardiovascular Health Score in Relation to Arrhythmias on Extended Ambulatory Electrocardiographic Monitoring (from the Multi-Ethnic Study of Atherosclerosis)." Am J Cardiol. 2022;170:63-70.
Yoshida Y, Chen Z, Baudier RL, et al. "Menopausal hormone therapy and risk of cardiovascular events in women with prediabetes or type 2 diabetes: A pooled analysis of 2917 postmenopausal women." Atherosclerosis. 2022;344:13-19.
Palta P, Griswold M, Ranadive R, et al. "Midlife Cardiovascular Health and Robust Versus Frail Late-Life Status: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2022;77(6):1222-1229.
Jia X, Sun C, Nambi V, et al. "Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2022;350:82-89.
Hu X, Mok Y, Ding N, et al. "Physical Function and Subsequent Risk of Cardiovascular Events in Older Adults: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(17):e025780.
Thomas EA, Enduru N, Tin A, et al. "Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke." J Am Heart Assoc. 2022;11(15):e025703.
Highland HM, Wojcik GL, Graff M, et al. "Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits." Am J Hum Genet. 2022;109(4):669-679.
Nonterah EA, Crowther NJ, Klipstein-Grobusch K, et al. "Racial and Ethnic Differences in the Association Between Classical Cardiovascular Risk Factors and Common Carotid Intima-Media Thickness: An Individual Participant Data Meta-Analysis." J Am Heart Assoc. 2022;11(15):e023704.
Ahmad MImtiaz, Tk L-A, Anees MAli, Chen LYee, Soliman EZ. "Relation of Electrocardiographic Abnormal P-Wave Axis With Stroke Mortality in the General Population." Am J Cardiol. 2022;180:59-64.
Jia Y, Li D, Yu J, et al. "Subclinical cardiovascular disease and frailty risk: the atherosclerosis risk in communities study." BMC Geriatr. 2022;22(1):321.
2021
Zhang Y, Pletcher MJ, Vittinghoff E, et al. "Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events." JAMA Cardiol. 2021;6(12):1406-1413.
Bell EJ, Bielinski SJ, St Sauver JL, et al. "Association of Proton Pump Inhibitors With Higher Risk of Cardiovascular Disease and Heart Failure." Mayo Clin Proc. 2021;96(10):2540-2549.
Do WL, Nguyen S, Yao J, et al. "Associations between DNA methylation and BMI vary by metabolic health status: a potential link to disparate cardiovascular outcomes." Clin Epigenetics. 2021;13(1):230.
Honda Y, Mok Y, Ishigami J, et al. "The Fifth-Generation Cardiac Troponin T and Cardiovascular Disease in the Community." J Am Coll Cardiol. 2021;78(20):2019-2021.
Schunk SJ, Kleber ME, März W, et al. "Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality." Eur Heart J. 2021;42(18):1742-1756.
Raffield LM, Howard AGreen, Graff M, et al. "Obesity Duration, Severity, and Distribution Trajectories and Cardiovascular Disease Risk in the Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2021;10(24):e019946.
"SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe." Eur Heart J. 2021;42(25):2439-2454.
"SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions." Eur Heart J. 2021;42(25):2455-2467.
2020
Hu EA, Steffen LM, Coresh JJ, Appel LJ. "Adherence to the Healthy Eating Index-2015 and Other Dietary Patterns May Reduce Risk of Cardiovascular Disease, Cardiovascular Mortality, and All-Cause Mortality." J Nutr. 2020;150(2):312-321.
Gaye B, Tajeu GS, Vasan RS, et al. "Association of Changes in Cardiovascular Health Metrics and Risk of Subsequent Cardiovascular Disease and Mortality." J Am Heart Assoc. 2020;9(19):e017458.
Poon AK, Meyer ML, Tanaka H, et al. "Association of insulin resistance, from mid-life to late-life, with aortic stiffness in late-life: the Atherosclerosis Risk in Communities Study." Cardiovasc Diabetol. 2020;19(1):11.
McEvoy JW, Daya N, Rahman F, et al. "Association of Isolated Diastolic Hypertension as Defined by the 2017 ACC/AHA Blood Pressure Guideline With Incident Cardiovascular Outcomes." JAMA. 2020;323(4):329-338.
Cowan LT, Lakshminarayan K, Lutsey PL, Beck J, Offenbacher S. "Endodontic therapy and incident cardiovascular disease: The Atherosclerosis Risk in Communities (ARIC) study." J Public Health Dent. 2020;80(1):79-91.
Ishigami J, Cowan LT, Demmer RT, et al. "Incident Hospitalization with Major Cardiovascular Diseases and Subsequent Risk of ESKD: Implications for Cardiorenal Syndrome." J Am Soc Nephrol. 2020;31(2):405-414.
Gondalia R, Holliday KM, Baldassari A, et al. "Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
Tang O, Matsushita K, Coresh JJ, et al. "Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
Ntalla I, Weng L-C, Cartwright JH, et al. "Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction." Nat Commun. 2020;11(1):2542.
Lee AK, Woodward M, Wang D, et al. "The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE." J Clin Endocrinol Metab. 2020;105(1).
2019
Oliver-Williams C, Vladutiu CJ, Loehr LR, Rosamond WD. "The Association Between Parity and Subsequent Cardiovascular Disease in Women: The Atherosclerosis Risk in Communities Study." J Womens Health (Larchmt). 2019;28(5):721-727.
Almuwaqqat Z, Jokhadar M, Norby FL, et al. "Association of Antidepressant Medication Type With the Incidence of Cardiovascular Disease in the ARIC Study." J Am Heart Assoc. 2019;8(11):e012503.
Porter AK, Schilsky S, Evenson KR, Florido R, Palta P, Holliday KM. "The Association of Sport and Exercise Activities With Cardiovascular Disease Risk: The Atherosclerosis Risk in Communities (ARIC) Study." J Phys Act Health. 2019;16(9):698-705.
Zhang Y, Vittinghoff E, Pletcher MJ, et al. "Associations of Blood Pressure and Cholesterol Levels During Young Adulthood With Later Cardiovascular Events." J Am Coll Cardiol. 2019;74(3):330-341.
Ishigami J, Hoogeveen RC, Ballantyne CM, Folsom AR, Coresh JJ, Selvin E. "Associations of High-Sensitivity Cardiac Troponin and Natriuretic Peptide With Subsequent Risk of Infection in Persons Without Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2019;188(12):2146-2155.
Kraja AT, Liu C, Fetterman JL, et al. "Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits." Am J Hum Genet. 2019;104(1):112-138.
Matsushita K, Ding N, Kim ED, et al. "Cardio-ankle vascular index and cardiovascular disease: Systematic review and meta-analysis of prospective and cross-sectional studies." J Clin Hypertens (Greenwich). 2019;21(1):16-24.
Gregson J, Kaptoge S, Bolton T, et al. "Cardiovascular Risk Factors Associated With Venous Thromboembolism." JAMA Cardiol. 2019;4(2):163-173.
Liu S, Kim ED, Wu A, et al. "Central and peripheral pulse wave velocity and subclinical myocardial stress and damage in older adults." PLoS One. 2019;14(2):e0212892.
George KM, Folsom AR, Steffen LM, Wagenknecht LE. "Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey: 1985-2015 vs The Atherosclerosis Risk in Communities Study Cohort: 1987-2015." Ethn Dis. 2019;29(1):47-52.
Barrett JK, Huille R, Parker R, Yano Y. "Estimating the association between blood pressure variability and cardiovascular disease: An application using the ARIC Study." Stat Med. 2019;38(10):1855-1868.
Huan T, Joehanes R, Song C, et al. "Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease." Nat Commun. 2019;10(1):4267.
Oyenuga AO, Folsom AR, Cheng S, Tanaka H. "Greater Adherence to Life's Simple 7 Is Associated With Less Arterial Stiffness: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2019;32(8):769-776.
Selvaraj S, Seidelmann S, Silvestre OM, et al. "HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study." Hypertension. 2019;73(1):68-74.
Grams ME, Surapaneni A, Ballew SH, et al. " Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis." J Am Soc Nephrol. 2019;30(10):2027-2036.
Saeed A, Sun W, Agarwala A, et al. "Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
Wang SY, Tan ASL, Claggett B, et al. "Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(12):1203-1212.
Matsushita K, Sang Y, Chen J, et al. "Novel "Predictor Patch" Method for Adding Predictors Using Estimates From Outside Datasets　- A Proof-of-Concept Study Adding Kidney Measures to Cardiovascular Mortality Prediction." Circ J. 2019;83(9):1876-1882.
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Coresh JJ. "Plant-Based Diets Are Associated With a Lower Risk of Incident Cardiovascular Disease, Cardiovascular Disease Mortality, and All-Cause Mortality in a General Population of Middle-Aged Adults." J Am Heart Assoc. 2019;8(16):e012865.
Kim ED, Ballew SH, Tanaka H, Heiss G, Coresh JJ. "Short-Term Prognostic Impact of Arterial Stiffness in Older Adults Without Prevalent Cardiovascular Disease." Hypertension. 2019;74(6):1373-1382.
Juraschek SP, Daya N, Appel LJ, et al. "Subclinical Cardiovascular Disease and Fall Risk in Older Adults: Results From the Atherosclerosis Risk in Communities Study." J Am Geriatr Soc. 2019;67(9):1795-1802.
Tin A, Marten J, Kuhns VLHalperin, et al. "Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels." Nat Genet. 2019;51(10):1459-1474.
2018
Garg PK, O'Neal WT, Chen LYee, Loehr LR, Sotoodehnia N, Soliman EZ. "American Heart Association's Life Simple 7 and Risk of Atrial Fibrillation in a Population Without Known Cardiovascular Disease: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(8).
Federspiel JJ, Sueta CA, Kucharska-Newton AMaria, et al. "Antihypertensive adherence and outcomes among community-dwelling Medicare beneficiaries: the Atherosclerosis Risk in Communities Study." J Eval Clin Pract. 2018;24(1):48-55.
Kim ED, Tanaka H, Ballew SH, Sang Y, Heiss G, Coresh JJ. "Associations Between Kidney Disease Measures and Regional Pulse Wave Velocity in a Large Community-Based Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(5):682-690.
Evangelou E, Warren HR, Mosen-Ansorena D, et al. "Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
Li C, Grove ML, Yu B, Jones BC, Morrison A, Boerwinkle E. "Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population." Hum Genet. 2018;137(1):85-94.
Seidelmann SB, Feofanova E, Yu B, et al. "Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk." J Am Coll Cardiol. 2018;72(15):1763-1773.
Ishigami J, Grams ME, Naik RP, et al. "Hemoglobin, Albuminuria, and Kidney Function in Cardiovascular Risk: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(2).
Cowan LT, Lutsey PL, Pankow JS, Matsushita K, Ishigami J. "Inpatient and Outpatient Infection as a Trigger of Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2018;7(22):e009683.
Mok Y, Ballew SH, Bash LD, et al. "International Validation of the Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention in Post-MI Patients: A Collaborative Analysis of the Chronic Kidney Disease Prognosis Consortium and the Risk Validation Scientific Committee." J Am Heart Assoc. 2018;7(14).
Folsom AR, Lutsey PL, Heckbert SR, et al. "Longitudinal increases in blood biomarkers of inflammation or cardiovascular disease and the incidence of venous thromboembolism." J Thromb Haemost. 2018;16(10):1964-1972.
Knopman DS, Gottesman RF, Sharrett ARichey, et al. "Midlife vascular risk factors and midlife cognitive status in relation to prevalence of mild cognitive impairment and dementia in later life: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2018;14(11):1406-1415.
Juraschek SP, Daya N, Appel LJ, et al. "Orthostatic Hypotension and Risk of Clinical and Subclinical Cardiovascular Disease in Middle-Aged Adults." J Am Heart Assoc. 2018;7(10).
Roetker NS, Pankow JS, Bressler J, Morrison AC. "Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities)." Circ Genom Precis Med. 2018;11(3):e001937.
Saeed A, Feofanova EV, Yu B, et al. "Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease." J Am Coll Cardiol. 2018;72(2):156-169.
George KM, Selvin E, Pankow JS, B Windham G. "Sex Differences in the Association of Diabetes With Cardiovascular Disease Outcomes Among African-American and White Participants in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2018;187(3):403-410.
Saeed A, Nambi V, Sun W, et al. "Short-Term Global Cardiovascular Disease Risk Prediction in Older Adults." J Am Coll Cardiol. 2018;71(22):2527-2536.
2017
Haycock PC, Burgess S, Nounu A, et al. "Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study." JAMA Oncol. 2017;3(5):636-651.
Kubota Y, Heiss G, Maclehose RF, Roetker NS. "Association of Educational Attainment With Lifetime Risk of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Intern Med. 2017;177(8):1165-1172.
van Capelleveen JC, Bochem AE, S Boekholdt M, et al. "Association of High-Density Lipoprotein-Cholesterol Versus Apolipoprotein A-I With Risk of Coronary Heart Disease: The European Prospective Investigation Into Cancer-Norfolk Prospective Population Study, the Atherosclerosis Risk in Communities Study, and ." J Am Heart Assoc. 2017;6(8).
Ashar FN, Zhang Y, Longchamps RJ, et al. "Association of Mitochondrial DNA Copy Number With Cardiovascular Disease." JAMA Cardiol. 2017;2(11):1247-1255.
Kucharska-Newton AMaria, Griswold M, Yao ZHoward, et al. "Cardiovascular Disease and Patterns of Change in Functional Status Over 15 Years: Findings From the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2017;6(3).
Nadruz W, Kitzman D, Windham BGwen, et al. "Cardiovascular Dysfunction and Frailty Among Older Adults in the Community: The ARIC Study." J Gerontol A Biol Sci Med Sci. 2017;72(7):958-964.

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