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ARIC Publications

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Mok Y, Ballew SH, Stacey RBrandon, et al. "Albuminuria and Prognosis Among Individuals With Atherosclerotic Cardiovascular Disease: The ARIC Study." J Am Coll Cardiol. 2021;78(1):87-89.
Patel RS, Schmidt AF, Tragante V, et al. "Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events." Circ Genom Precis Med. 2019;12(4):e002471.
de Vries PS, Sabater-Lleal M, Huffman JE, et al. "A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology." Blood. 2019;133(9):967-977.
Ashar FN, Mitchell RN, Albert CM, et al. "A comprehensive evaluation of the genetic architecture of sudden cardiac arrest." Eur Heart J. 2018;39(44):3961-3969.
Stitziel NO, Khera AV, Wang X, et al. "ANGPTL3 Deficiency and Protection Against Coronary Artery Disease." J Am Coll Cardiol. 2017;69(16):2054-2063.
Zhang Y, Guallar E, Ashar FN, et al. "Association between mitochondrial DNA copy number and sudden cardiac death: findings from the Atherosclerosis Risk in Communities study (ARIC)." Eur Heart J. 2017;38(46):3443-3448.
Mendelson MM, Marioni RE, Joehanes R, et al. "Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach." PLoS Med. 2017;14(1):e1002215.
Aronis KN, Zhao D, Hoogeveen RC, et al. "Associations of Lipoprotein(a) Levels With Incident Atrial Fibrillation and Ischemic Stroke: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2017;6(12).
Liu DJ, Peloso GM, Yu H, et al. "Exome-wide association study of plasma lipids in >300,000 individuals." Nat Genet. 2017;49(12):1758-1766.
Howson JMM, Zhao W, Barnes DR, et al. "Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms." Nat Genet. 2017;49(7):1113-1119.
Jansen H, Willenborg C, Lieb W, et al. "Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation." J Rheumatol. 2017;44(1):4-10.
Lubin JH, Couper DJ, Lutsey PL. "Synergistic and Non-synergistic Associations for Cigarette Smoking and Non-tobacco Risk Factors for Cardiovascular Disease Incidence in the Atherosclerosis Risk In Communities (ARIC) Study." Nicotine Tob Res. 2017;19(7):826-835.
Colantonio LD, Bittner V, Reynolds K, et al. "Association of Serum Lipids and Coronary Heart Disease in Contemporary Observational Studies." Circulation. 2016;133(3):256-64.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Bundle branch blocks and the risk of mortality in the Atherosclerosis Risk in Communities study." J Cardiovasc Med (Hagerstown). 2016;17(6):411-7.
Khera AV, Won H-H, Peloso GM, et al. "Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia." J Am Coll Cardiol. 2016;67(22):2578-89.
McEvoy JW, Chen Y, Rawlings A, et al. "Diastolic Blood Pressure, Subclinical Myocardial Damage, and Cardiac Events: Implications for Blood Pressure Control." J Am Coll Cardiol. 2016;68(16):1713-1722.
Dehghan A, Bis JC, White CC, et al. "Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium." PLoS One. 2016;11(3):e0144997.
Petruski-Ivleva N, Viera AJ, Shimbo D, et al. "Longitudinal Patterns of Change in Systolic Blood Pressure and Incidence of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." Hypertension. 2016;67(6):1150-6.
Natarajan P, Bis JC, Bielak LF, et al. "Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis." Circ Cardiovasc Genet. 2016;9(6):511-520.
Folsom AR, Gottesman RF, Appiah D, Shahar E. "Plasma d-Dimer and Incident Ischemic Stroke and Coronary Heart Disease: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(1):18-23.
Gonçalves A, Claggett B, Jhund PS, et al. "Alcohol consumption and risk of heart failure: the Atherosclerosis Risk in Communities Study." Eur Heart J. 2015;36(15):939-45.
Waks JW, Soliman EZ, Henrikson CA, et al. "Beat-to-beat spatiotemporal variability in the T vector is associated with sudden cardiac death in participants without left ventricular hypertrophy: the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2015;4(1):e001357.
Nikpay M, Goel A, Won H-H, et al. "A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease." Nat Genet. 2015;47(10):1121-1130.
Rautaharju PM, Zhang Z-M, Haisty WK, Kucharska-Newton AMaria, Rosamond WD. "Electrocardiographic repolarization-related predictors of coronary heart disease and sudden cardiac deaths in men and women with cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study." J Electrocardiol. 2015;48(1):101-11.
Do R, Stitziel NO, Won H-H, et al. "Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction." Nature. 2015;518(7537):102-6.
Jansen H, Loley C, Lieb W, et al. "Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk." Atherosclerosis. 2015;241(2):419-26.
Holmes MV, Asselbergs FW, Palmer TM, et al. "Mendelian randomization of blood lipids for coronary heart disease." Eur Heart J. 2015;36(9):539-50.
Naorungroj S, Schoenbach VJ, Wruck L, et al. "Tooth loss, periodontal disease, and cognitive decline in the Atherosclerosis Risk in Communities (ARIC) study." Community Dent Oral Epidemiol. 2015;43(1):47-57.
Zhang Z-M, Rautaharju PM, Prineas RJ, Whitsel EA, Tereshchenko L. "A wide QRS/T angle in bundle branch blocks is associated with increased risk for coronary heart disease and all-cause mortality in the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2015;48(4):672-7.
Selvin E, Lazo M, Chen Y, et al. "Diabetes mellitus, prediabetes, and incidence of subclinical myocardial damage." Circulation. 2014;130(16):1374-82.
Yaghootkar H, Scott RA, White CC, et al. "Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes." Diabetes. 2014;63(12):4369-77.
Huang J, Huffman JE, Yamakuchi M, et al. "Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2." Arterioscler Thromb Vasc Biol. 2014;34(5):1093-101.
Gupta DK, Skali H, Claggett B, et al. "Heart failure risk across the spectrum of ankle-brachial index: the ARIC study (Atherosclerosis Risk In Communities)." JACC Heart Fail. 2014;2(5):447-54.
Ndumele CE, Coresh JJ, Lazo M, et al. "Obesity, subclinical myocardial injury, and incident heart failure." JACC Heart Fail. 2014;2(6):600-7.
Rautaharju PM, Zhang Z-M, Haisty WK, et al. "Race- and sex-associated differences in rate-adjusted QT, QTpeak, ST elevation and other regional measures of repolarization: the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2014;47(3):342-50.
Dichgans M, Malik R, König IR, et al. "Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants." Stroke. 2014;45(1):24-36.
Lusk CM, Dyson G, Clark AG, et al. "Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study." Hum Genet. 2014;133(9):1105-16.
Katz EG, Stevens J, Truesdale KP, Cai J, North KE. "Associations of body mass index with incident hypertension in American white, American black and Chinese Asian adults in early and middle adulthood: the Coronary Artery Risk Development in Young Adults (CARDIA) study, the Atherosclerosis Risk in Communiti." Asia Pac J Clin Nutr. 2013;22(4):626-34.
Do R, Willer CJ, Schmidt EM, et al. "Common variants associated with plasma triglycerides and risk for coronary artery disease." Nat Genet. 2013;45(11):1345-52.
Lieb W, Jansen H, Loley C, et al. "Genetic predisposition to higher blood pressure increases coronary artery disease risk." Hypertension. 2013;61(5):995-1001.
Kang S, Cai J, Chambless L. "Marginal additive hazards model for case-cohort studies with multiple disease outcomes: an application to the Atherosclerosis Risk in Communities (ARIC) study." Biostatistics. 2013;14(1):28-41.
Sabater-Lleal M, Huang J, Chasman D, et al. "Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease." Circulation. 2013;128(12):1310-24.
Pendergrass SA, Brown-Gentry K, Dudek S, et al. "Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network." PLoS Genet. 2013;9(1):e1003087.
Dastani Z, Johnson T, Kronenberg F, et al. "The shared allelic architecture of adiponectin levels and coronary artery disease." Atherosclerosis. 2013;229(1):145-8.
Bressler J, Fornage M, Hanis CL, et al. "The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts." BMC Med Genet. 2009;10:56.
Breslow NE, Lumley T, Ballantyne CM, Chambless LE, Kulich M. "Using the whole cohort in the analysis of case-cohort data." Am J Epidemiol. 2009;169(11):1398-405.
Cheung N, Rogers S, Mosley TH, Klein R, Couper D, Wong TY. "Vital exhaustion and retinal microvascular changes in cardiovascular disease: atherosclerosis risk in communities study." Psychosom Med. 2009;71(3):308-12.
Shahar E, Heiss G, Rosamond WD, Szklo M. "Baldness and myocardial infarction in men: the atherosclerosis risk in communities study." Am J Epidemiol. 2008;167(6):676-83.
Assimes TL, Knowles JW, Priest JR, et al. "Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease." Hum Genet. 2008;123(4):399-408.
Knowles JW, Assimes TL, Boerwinkle E, et al. "Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD." BMC Med Genet. 2008;9:23.
Nambi V, Morrison AC, Hoogeveen RC, et al. "Matrix metalloproteinase-1 and tissue inhibitors do not predict incident coronary artery disease in the atherosclerosis risk in communities (ARIC) study." Tex Heart Inst J. 2008;35(4):388-94.
Assimes TL, Knowles JW, Priest JR, et al. "A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease." Atherosclerosis. 2008;198(1):136-44.
Liew G, Wang J J, Klein R, et al. "The relationship between birthweight and early age-related maculopathy: the atherosclerosis risk in communities study." Ophthalmic Epidemiol. 2008;15(1):56-61.
Schanen JG, Iribarren C, Shahar E, et al. "Asthma and incident cardiovascular disease: the Atherosclerosis Risk in Communities Study." Thorax. 2005;60(8):633-8.
Selvin E, Coresh J, Golden SH, Brancati FL, Folsom AR, Steffes MW. "Glycemic control and coronary heart disease risk in persons with and without diabetes: the atherosclerosis risk in communities study." Arch Intern Med. 2005;165(16):1910-6.
Taylor HA, Clark BL, Garrison RJ, et al. "Relation of aortic valve sclerosis to risk of coronary heart disease in African-Americans." Am J Cardiol. 2005;95(3):401-4.
Wattanakit K, Folsom AR, Selvin E, et al. "Risk factors for peripheral arterial disease incidence in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2005;180(2):389-97.