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ARIC Publications

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Maheshwari A, Norby FL, Soliman EZ, et al. "Abnormal P-Wave Axis and Ischemic Stroke: The ARIC Study (Atherosclerosis Risk In Communities)." Stroke. 2017;48(8):2060-2065.
Huxley RR, Lopez FL, Folsom AR, et al. "Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2011;123(14):1501-8.
Hunt KJ, Evans GW, Folsom AR, et al. "Acoustic shadowing on B-mode ultrasound of the carotid artery predicts ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2001;32(5):1120-6.
O'Neal WT, Kamel H, Zhang Z-M, Chen LYee, Alonso A. "Advanced interatrial block and ischemic stroke: The Atherosclerosis Risk in Communities Study." Neurology. 2016;87(4):352-6.
M Ikram K, Mitchell P, Klein R, Sharrett ARichey, Couper DJ. "Age-related macular degeneration and long-term risk of stroke subtypes." Stroke. 2012;43(6):1681-3.
Wong T Y, Klein R, Sun C, et al. "Age-related macular degeneration and risk for stroke." Ann Intern Med. 2006;145(2):98-106.
Tsai AW, Folsom AR, Rosamond WD, Jones DW. "Ankle-brachial index and 7-year ischemic stroke incidence: the ARIC study." Stroke. 2001;32(8):1721-4.
Sturgeon JD, Folsom AR, Bray MS, Boerwinkle E, Ballantyne CM. "Apolipoprotein E genotype and incident ischemic stroke: the Atherosclerosis Risk in Communities Study." Stroke. 2005;36(11):2484-6.
Holmes MV, Dale CE, Zuccolo L, et al. "Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data." BMJ. 2014;349:g4164.
Srinath R, Gottesman RF, Golden SHill, Carson KA. "Association Between Endogenous Testosterone and Cerebrovascular Disease in the ARIC Study (Atherosclerosis Risk in Communities)." Stroke. 2016;47(11):2682-2688.
Johnson EL, Krauss GL, Lee AK, et al. "Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study." JAMA Neurol. 2018;75(11):1375-1382.
Oliver-Williams C, Vladutiu CJ, Loehr LR, Rosamond WD. "The Association Between Parity and Subsequent Cardiovascular Disease in Women: The Atherosclerosis Risk in Communities Study." J Womens Health (Larchmt). 2019;28(5):721-727.
Autenrieth CS, Evenson KR, Yatsuya H, Shahar E, Baggett C. "Association between physical activity and risk of stroke subtypes: the atherosclerosis risk in communities study." Neuroepidemiology. 2013;40(2):109-16.
Chambless LE, Toole JF, Nieto JF, Rosamond W, Paton C. "Association between symptoms reported in a population questionnaire and future ischemic stroke: the ARIC study." Neuroepidemiology. 2004;23(1-2):33-7.
Williams JE, Nieto JF, Sanford CP, Couper DJ, Tyroler HA. "The association between trait anger and incident stroke risk: the Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 2002;33(1):13-9.
Selvin E, Rawlings A, Lutsey PL, Maruthur N, Pankow JS, Steffes M. "Association of 1,5-Anhydroglucitol With Cardiovascular Disease and Mortality." Diabetes. 2016;65(1):201-8.
Di Angelantonio E, Kaptoge S, Wormser D, et al. "Association of Cardiometabolic Multimorbidity With Mortality." JAMA. 2015;314(1):52-60.
Haring B, Misialek JR, Rebholz CM, Petruski-Ivleva N, Gottesman RF, Mosley TH. "Association of Dietary Protein Consumption With Incident Silent Cerebral Infarcts and Stroke: The Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 2015;46(12):3443-50.
Ogagarue ER, Lutsey PL, Klein R, Klein BE. "Association of ideal cardiovascular health metrics and retinal microvascular findings: the Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2013;2(6):e000430.
Mahmoodi BK, Yatsuya H, Matsushita K, et al. "Association of kidney disease measures with ischemic versus hemorrhagic strokes: pooled analyses of 4 prospective community-based cohorts." Stroke. 2014;45(7):1925-31.
Rawlings AM, Juraschek SP, Heiss G, et al. "Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline." Neurology. 2018;91(8):e759-e768.
Matsushita K, Williams EK, Mongraw-Chaffin ML, et al. "The association of plasma lactate with incident cardiovascular outcomes: the ARIC Study." Am J Epidemiol. 2013;178(3):401-9.
Appiah D, Schreiner PJ, Maclehose RF. "Association of Plasma γ' Fibrinogen With Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb Vasc Biol. 2015;35(12):2700-6.
Kwon Y, Norby FL, Jensen PN, et al. "Association of Smoking, Alcohol, and Obesity with Cardiovascular Death and Ischemic Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study and Cardiovascular Health Study (CHS)." PLoS One. 2016;11(1):e0147065.
Volcik KA, Ballantyne CM, Braun MC, Coresh J, Mosley TH, Boerwinkle E. "Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study." Am J Hypertens. 2008;21(5):533-8.
Mishra A, Chauhan G, Violleau M-H, et al. "Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects." Brain. 2019;142(4):1009-1023.
Carty CL, Bůžková P, Fornage M, et al. "Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study." Circ Cardiovasc Genet. 2012;5(2):210-6.
Virani SS, Brautbar A, Davis BC, et al. "Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2012;125(2):241-9.
Cuthbertson CC, Tan X, Heiss G, Kucharska-Newton AMaria, Nichols HB, Kubota Y. "Associations of Leisure-Time Physical Activity and Television Viewing With Life Expectancy Free of Nonfatal Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2019;8(18):e012657.
Yatsuya H, Yamagishi K, North KE, Brancati FL, Stevens J, Folsom AR. "Associations of obesity measures with subtypes of ischemic stroke in the ARIC Study." J Epidemiol. 2010;20(5):347-54.
Steffen LM, Jacobs DR, Stevens J, Shahar E, Carithers T, Folsom AR. "Associations of whole-grain, refined-grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2003;78(3):383-90.
Schanen JG, Iribarren C, Shahar E, et al. "Asthma and incident cardiovascular disease: the Atherosclerosis Risk in Communities Study." Thorax. 2005;60(8):633-8.
Kshirsagar AV, Carpenter M, Bang H, Wyatt SB, Colindres RE. "Blood pressure usually considered normal is associated with an elevated risk of cardiovascular disease." Am J Med. 2006;119(2):133-41.
"Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis." Lancet Diabetes Endocrinol. 2015;3(4):243-53.
Lee C D, Folsom AR, Pankow JS, Brancati FL. "Cardiovascular events in diabetic and nondiabetic adults with or without history of myocardial infarction." Circulation. 2004;109(7):855-60.
Yang EY, Chambless L, Sharrett ARichey, et al. "Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2012;43(1):103-8.
Ohira T, Shahar E, Iso H, et al. "Carotid artery wall thickness and risk of stroke subtypes: the atherosclerosis risk in communities study." Stroke. 2011;42(2):397-403.
Bekwelem W, Jensen PN, Norby FL, et al. "Carotid Atherosclerosis and Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1643-6.
Chambless LE, Folsom AR, Clegg LX, et al. "Carotid wall thickness is predictive of incident clinical stroke: the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2000;151(5):478-87.
Holmes MV, Lange LA, Palmer T, et al. "Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
Wong T Y, Klein R, A Sharrett R, et al. "Cerebral white matter lesions, retinopathy, and incident clinical stroke." JAMA. 2002;288(1):67-74.
Rathore SS, Hinn AR, Cooper LS, Tyroler HA, Rosamond WD. "Characterization of incident stroke signs and symptoms: findings from the atherosclerosis risk in communities study." Stroke. 2002;33(11):2718-21.
Ding N, Sang Y, Chen J, et al. "Cigarette Smoking, Smoking Cessation, and Long-Term Risk of 3 Major Atherosclerotic Diseases." J Am Coll Cardiol. 2019;74(4):498-507.
Georgakis MK, Malik R, Björkbacka H, et al. "Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals." Circ Res. 2019;125(8):773-782.
Yang EY, Nambi V, Tang Z, et al. "Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study." J Am Coll Cardiol. 2009;54(25):2388-95.
Huxley RR, Bell EJ, Lutsey PL, et al. "A comparative analysis of risk factors for stroke in blacks and whites: the Atherosclerosis Risk in Communities study." Ethn Health. 2014;19(6):601-16.
Alonso A, Knopman DS, Gottesman RF, et al. "Correlates of Dementia and Mild Cognitive Impairment in Patients With Atrial Fibrillation: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Am Heart Assoc. 2017;6(7).
Sood SL, Cheng D, Ragni M, et al. "A cross-sectional analysis of cardiovascular disease in the hemophilia population." Blood Adv. 2018;2(11):1325-1333.
Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. "Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study." Clin Pharmacol Ther. 2008;83(1):52-60.
Silvestre OM, Nadruz W, Roca GQuerejeta, et al. "Declining Lung Function and Cardiovascular Risk: The ARIC Study." J Am Coll Cardiol. 2018;72(10):1109-1122.
Rasmussen-Torvik LJ, Yatsuya H, Selvin E, Alonso A, Folsom AR. "Demographic and cardiovascular risk factors modify association of fasting insulin with incident coronary heart disease and ischemic stroke (from the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2010;105(10):1420-5.
McEvoy JW, Chen Y, Rawlings A, et al. "Diastolic Blood Pressure, Subclinical Myocardial Damage, and Cardiac Events: Implications for Blood Pressure Control." J Am Coll Cardiol. 2016;68(16):1713-1722.
Knopman DS, Mosley TH, Catellier DJ, Coker LH. "Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study." Alzheimers Dement. 2009;5(3):207-14.
Selvin E, Rawlings AM, Lutsey PL, Maruthur N, Pankow JS, Steffes M. "Fructosamine and Glycated Albumin and the Risk of Cardiovascular Outcomes and Death." Circulation. 2015;132(4):269-77.
Holliday EG, Traylor M, Malik R, et al. "Genetic overlap between diagnostic subtypes of ischemic stroke." Stroke. 2015;46(3):615-9.
Traylor M, Farrall M, Holliday EG, et al. "Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies." Lancet Neurol. 2012;11(11):951-62.
Yamagishi K, Folsom AR, Rosamond WD, Boerwinkle E. "A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study." Eur Heart J. 2009;30(10):1222-8.
Ehret GB, Munroe PB, Rice KM, et al. "Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk." Nature. 2011;478(7367):103-9.
Traylor M, Malik R, Nalls MA, et al. "Genetic variation at 16q24.2 is associated with small vessel stroke." Ann Neurol. 2017;81(3):383-394.
Cheng Y-C, Stanne TM, Giese A-K, et al. "Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2." Stroke. 2016;47(2):307-16.
M Ikram A, Seshadri S, Bis JC, et al. "Genomewide association studies of stroke." N Engl J Med. 2009;360(17):1718-28.
Huang J, Huffman JE, Yamakuchi M, et al. "Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2." Arterioscler Thromb Vasc Biol. 2014;34(5):1093-101.
de Vries PS, Sabater-Lleal M, Huffman JE, et al. "A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology." Blood. 2019;133(9):967-977.
Keene KL, Hyacinth HI, Bis JC, et al. "Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke." Stroke. 2020;51(8):2454-2463.
Selvin E, Coresh J, Shahar E, Zhang L, Steffes M, A Sharrett R. "Glycaemia (haemoglobin A1c) and incident ischaemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study." Lancet Neurol. 2005;4(12):821-6.
Bower JK, Appel LJ, Matsushita K, Young HJ, Alonso A, Brancati FL. "Glycated hemoglobin and risk of hypertension in the atherosclerosis risk in communities study." Diabetes Care. 2012;35(5):1031-7.
Di Angelantonio E, Gao P, Khan H, et al. "Glycated hemoglobin measurement and prediction of cardiovascular disease." JAMA. 2014;311(12):1225-33.
Morrison AC, Doris PA, Folsom AR, Nieto FJ, Boerwinkle E. "G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke." Stroke. 2001;32(4):822-9.
Offenbacher S, Jiao Y, Kim SJ, et al. "GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation." Nat Commun. 2018;9(1):3686.
Stang PE, Carson AP, Rose KM, et al. "Headache, cerebrovascular symptoms, and stroke: the Atherosclerosis Risk in Communities Study." Neurology. 2005;64(9):1573-7.
Fyfe-Johnson AL, Muller CJ, Alonso A, et al. "Heart Rate Variability and Incident Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1452-8.
Kubota Y, Chen LYee, Whitsel EA. "Heart rate variability and lifetime risk of cardiovascular disease: the Atherosclerosis Risk in Communities Study." Ann Epidemiol. 2017;27(10):619-625.e2.
Sturgeon JD, Folsom AR, Longstreth WT, Shahar E, Rosamond WD, Cushman M. "Hemostatic and inflammatory risk factors for intracerebral hemorrhage in a pooled cohort." Stroke. 2008;39(8):2268-73.
Alonso A, Tang W, Agarwal SK, Soliman EZ, Chamberlain AM, Folsom AR. "Hemostatic markers are associated with the risk and prognosis of atrial fibrillation: the ARIC study." Int J Cardiol. 2012;155(2):217-22.