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ARIC Publications

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2021
Zhang Y, Pletcher MJ, Vittinghoff E, et al. "Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events." JAMA Cardiol. 2021;6(12):1406-1413.
Sarnowski C, Cousminer DL, Franceschini N, et al. "Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche." Hum Reprod. 2021;36(7):1999-2010.
2020
Sadler B, Haller G, Antunes L, et al. "Rare and duplications containing in clubfoot." J Med Genet. 2020;57(12):851-857.
Chen G-C, Chai JChoul, Yu B, et al. "Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)." Am J Clin Nutr. 2020;112(1):57-65.
2019
Huang T, Wang T, Zheng Y, et al. "Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study." JAMA Netw Open. 2019;2(9):e1910915.
Zhang Y, Vittinghoff E, Pletcher MJ, et al. "Associations of Blood Pressure and Cholesterol Levels During Young Adulthood With Later Cardiovascular Events." J Am Coll Cardiol. 2019;74(3):330-341.
Yu B, Zanetti KA, Temprosa M, et al. "The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies." Am J Epidemiol. 2019;188(6):991-1012.
Syme C, Shin J, Richer L, Gaudet D, Fornage M, Paus T. "Epigenetic Loci of Blood Pressure." Circ Genom Precis Med. 2019;12(1):e002341.
Spracklen CN, Karaderi T, Yaghootkar H, et al. "Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
de Vries PS, Brown MR, Bentley AR, et al. "Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions." Am J Epidemiol. 2019;188(6):1033-1054.
Bentley AR, Sung YJ, Brown MR, et al. "Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids." Nat Genet. 2019;51(4):636-648.
Noordam R, Bos MM, Wang H, et al. "Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration." Nat Commun. 2019;10(1):5121.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
2018
Wang X, Pan Y, Zhu H, et al. "An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression." Clin Epigenetics. 2018;10:3.
Ligthart S, Vaez A, Võsa U, et al. "Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders." Am J Hum Genet. 2018;103(5):691-706.
"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017." Lancet. 2018;392(10159):1789-1858.
Oelsner EC, Balte PP, Cassano PA, et al. "Harmonization of Respiratory Data From 9 US Population-Based Cohorts: The NHLBI Pooled Cohorts Study." Am J Epidemiol. 2018;187(11):2265-2278.
Feitosa MF, Kraja AT, Chasman DI, et al. "Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries." PLoS One. 2018;13(6):e0198166.
Rosenthal EA, Shirts BH, Amendola LM, et al. "Rare loss of function variants in candidate genes and risk of colorectal cancer." Hum Genet. 2018;137(10):795-806.
Davies G, Lam M, Harris SE, et al. "Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function." Nat Commun. 2018;9(1):2098.
Hong J, Hatchell KE, Bradfield JP, et al. "Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations." J Clin Endocrinol Metab. 2018;103(4):1380-1392.
2017
Sanders AE, Sofer T, Wong Q, et al. "Chronic Periodontitis Genome-wide Association Study in the Hispanic Community Health Study / Study of Latinos." J Dent Res. 2017;96(1):64-72.
Day FR, Thompson DJ, Helgason H, et al. "Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk." Nat Genet. 2017;49(6):834-841.
Hibar DP, Adams HHH, Jahanshad N, et al. "Novel genetic loci associated with hippocampal volume." Nat Commun. 2017;8:13624.
2016
Mirzaa GM, Campbell CD, Solovieff N, et al. "Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism." JAMA Neurol. 2016;73(7):836-845.
"Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies." Lancet Neurol. 2016;15(7):695-707.
"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Harel T, Yesil G, Bayram Y, et al. "Monoallelic and Biallelic Variants in EMC1 Identified in Individuals with Global Developmental Delay, Hypotonia, Scoliosis, and Cerebellar Atrophy." Am J Hum Genet. 2016;98(3):562-570.
White J, Beck CR, Harel T, et al. "POGZ truncating alleles cause syndromic intellectual disability." Genome Med. 2016;8(1):3.
2015
Wei GS, Coady SA, Reis JP, et al. "Duration and Degree of Weight Gain and Incident Diabetes in Younger Versus Middle-Aged Black and White Adults: ARIC, CARDIA, and the Framingham Heart Study." Diabetes Care. 2015;38(11):2042-9.
Bayram Y, Gulsuner S, Guran T, et al. "Homozygous loss-of-function mutations in SOHLH1 in patients with nonsyndromic hypergonadotropic hypogonadism." J Clin Endocrinol Metab. 2015;100(5):E808-14.
Grams ME, Sang Y, Ballew SH, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):591-601.
Lunetta KL, Day FR, Sulem P, et al. "Rare coding variants and X-linked loci associated with age at menarche." Nat Commun. 2015;6:7756.
2014
Holmes MV, Lange LA, Palmer T, et al. "Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
Simino J, Shi G, Bis JC, et al. "Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia." Am J Hum Genet. 2014;95(1):24-38.
Perry JRb, Day F, Elks CE, et al. "Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche." Nature. 2014;514(7520):92-97.
2013
Fesinmeyer MD, North KE, Lim U, et al. "Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study." BMC Med Genet. 2013;14:6.
Spencer KL, Malinowski J, Carty CL, et al. "Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study." PLoS One. 2013;8(2):e55258.
Chen Z, Tang H, Qayyum R, et al. "Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network." Hum Mol Genet. 2013;22(12):2529-38.
Demerath EW, Liu C-T, Franceschini N, et al. "Genome-wide association study of age at menarche in African-American women." Hum Mol Genet. 2013;22(16):3329-46.
Corona G, Rastrelli G, Silverii A, et al. "The identification of prediabetes condition with ARIC algorithm predicts long-term CV events in patients with erectile dysfunction." J Sex Med. 2013;10(4):1114-23.
Graff M, Gordon-Larsen P, Lim U, et al. "The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study." Diabetes. 2013;62(5):1763-7.
Rosenthal EA, Ranchalis J, Crosslin DR, et al. "Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia." Am J Hum Genet. 2013;93(6):1035-45.
Sabater-Lleal M, Huang J, Chasman D, et al. "Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease." Circulation. 2013;128(12):1310-24.
2012
Hartz SM, Short SE, Saccone NL, et al. "Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers." Arch Gen Psychiatry. 2012;69(8):854-60.
Ellinor PT, Lunetta KL, Albert CM, et al. "Meta-analysis identifies six new susceptibility loci for atrial fibrillation." Nat Genet. 2012;44(6):670-5.
He C, Chasman DI, Dreyfus J, et al. "Reproductive aging-associated common genetic variants and the risk of breast cancer." Breast Cancer Res. 2012;14(2):R54.
2011
Wei GS, Coady SA, Goff DC, et al. "Blood pressure and the risk of developing diabetes in african americans and whites: ARIC, CARDIA, and the framingham heart study." Diabetes Care. 2011;34(4):873-9.
Wirka RC, Gore S, Van Wagoner DR, et al. "A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation." Circ Arrhythm Electrophysiol. 2011;4(1):87-93.
2010
Ellinor PT, Lunetta KL, Glazer NL, et al. "Common variants in KCNN3 are associated with lone atrial fibrillation." Nat Genet. 2010;42(3):240-4.
2009
Perry JRB, Stolk L, Franceschini N, et al. "Meta-analysis of genome-wide association data identifies two loci influencing age at menarche." Nat Genet. 2009;41(6):648-50.
Arking DE, Khera A, Xing C, et al. "Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population." PLoS One. 2009;4(1):e4333.
2008
Assimes TL, Knowles JW, Priest JR, et al. "Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease." Hum Genet. 2008;123(4):399-408.
2007
Hogan SL, Vupputuri S, Guo X, et al. "Association of cigarette smoking with albuminuria in the United States: the third National Health and Nutrition Examination Survey." Ren Fail. 2007;29(2):133-42.
2005
van Lenthe FJ, Borrell LN, Costa G, et al. "Neighbourhood unemployment and all cause mortality: a comparison of six countries." J Epidemiol Community Health. 2005;59(3):231-7.
2001
Arbes SJ, Agústsdóttir H, Slade GD. "Environmental tobacco smoke and periodontal disease in the United States." Am J Public Health. 2001;91(2):253-7.
1991
Folsom AR, Burke GL, Byers CL, et al. "Implications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies." Am J Clin Nutr. 1991;53(6 Suppl):1604S-1611S.