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ARIC Publications

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Adams HHH, Hibar DP, Chouraki V, et al. "Novel genetic loci underlying human intracranial volume identified through genome-wide association." Nat Neurosci. 2016;19(12):1569-1582.
Adib-Samii P, Rost N, Traylor M, et al. "17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status." Stroke. 2013;44(6):1609-15.
Allen HLango, Estrada K, Lettre G, et al. "Hundreds of variants clustered in genomic loci and biological pathways affect human height." Nature. 2010;467(7317):832-8.
Amendola LM, Dorschner MO, Robertson PD, et al. "Actionable exomic incidental findings in 6503 participants: challenges of variant classification." Genome Res. 2015;25(3):305-15.
Arking DE, Khera A, Xing C, et al. "Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population." PLoS One. 2009;4(1):e4333.
Arking DE, Pulit SL, Crotti L, et al. "Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization." Nat Genet. 2014;46(8):826-36.
Arking DE, Reinier K, Post W, et al. "Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest." PLoS One. 2010;5(3):e9879.
Arking DE, M Junttila J, Goyette P, et al. "Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals." PLoS Genet. 2011;7(6):e1002158.
Ashar FN, Mitchell RN, Albert CM, et al. "A comprehensive evaluation of the genetic architecture of sudden cardiac arrest." Eur Heart J. 2018;39(44):3961-3969.
Asselbergs FW, Guo Y, van Iperen EPA, et al. "Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci." Am J Hum Genet. 2012;91(5):823-38.
Assimes TL, Knowles JW, Priest JR, et al. "A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease." Atherosclerosis. 2008;198(1):136-44.
Assimes TL, Knowles JW, Priest JR, et al. "Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease." Hum Genet. 2008;123(4):399-408.
Auer PL, Johnsen JM, Johnson AD, et al. "Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project." Am J Hum Genet. 2012;91(5):794-808.
Avery CL, Sethupathy P, Buyske S, et al. "Fine-mapping and initial characterization of QT interval loci in African Americans." PLoS Genet. 2012;8(8):e1002870.
Avery CL, Sitlani CM, Arking DE, et al. "Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval." Pharmacogenomics J. 2014;14(1):6-13.
Avery CL, Wassel CL, Richard MA, et al. "Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations." Heart Rhythm. 2017;14(4):572-580.
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Barbalic M, Reiner AP, Wu C, et al. "Genome-wide association analysis of incident coronary heart disease (CHD) in African Americans: a short report." PLoS Genet. 2011;7(8):e1002199.
Bare LA, Morrison AC, Rowland CM, et al. "Five common gene variants identify elevated genetic risk for coronary heart disease." Genet Med. 2007;9(10):682-9.
Barral S, Cheng R, Reitz C, et al. "Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease." Alzheimers Dement. 2015;11(12):1397-1406.
Ben-Avraham D, Karasik D, Verghese J, et al. "The complex genetics of gait speed: genome-wide meta-analysis approach." Aging (Albany NY). 2017;9(1):209-246.
Benjamin EJ, Rice KM, Arking DE, et al. "Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry." Nat Genet. 2009;41(8):879-81.
Berndt SI, Gustafsson S, Mägi R, et al. "Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture." Nat Genet. 2013;45(5):501-12.
Bielinski SJ, Pankow JS, Folsom AR, North KE, Boerwinkle E. "TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2008;51(6):968-70.
Bielinski SJ, Pankow JS, Boerwinkle E, Bray MS, Kao LWH, Folsom AR. "Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study." Acta Diabetol. 2008;45(3):179-82.
Bien SA, Pankow JS, Haessler J, et al. "Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium." Diabetologia. 2017;60(12):2384-2398.
Bihlmeyer NA, Brody JA, Smith A V, et al. "ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals." Circ Genom Precis Med. 2018;11(1):e001758.
Bihlmeyer NA, Brody JA, Smith A V, et al. "Genetic diversity is a predictor of mortality in humans." BMC Genet. 2014;15:159.
Billings LK, Hsu Y-H, Ackerman RJ, et al. "Impact of common variation in bone-related genes on type 2 diabetes and related traits." Diabetes. 2012;61(8):2176-86.
Huang T, Wang T, Zheng Y, et al. "Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study." JAMA Netw Open. 2019;2(9):e1910915.
Bis JC, DeCarli C, Smith A V, et al. "Common variants at 12q14 and 12q24 are associated with hippocampal volume." Nat Genet. 2012;44(5):545-51.
Bis JC, Kavousi M, Franceschini N, et al. "Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque." Nat Genet. 2011;43(10):940-7.
Bis JC, Sitlani C, Irvin R, et al. "Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium." PLoS One. 2015;10(10):e0140496.
Bis JC, White CC, Franceschini N, et al. "Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):359-64.
Bis JC, Destefano A, Liu X, et al. "Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium." PLoS One. 2014;9(6):e99798.
Blue EE, Bis JC, Dorschner MO, et al. "Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project." Dement Geriatr Cogn Disord. 2018;45(1-2):1-17.
Boerwinkle E. "Following-up genome-wide association study signals: lessons learned from Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):332-4.
Boraska V, Jerončić A, Colonna V, et al. "Genome-wide meta-analysis of common variant differences between men and women." Hum Mol Genet. 2012;21(21):4805-15.
Brautbar A, Pompeii LA, Dehghan A, et al. "A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies." Atherosclerosis. 2012;223(2):421-6.
Bressler J, Kao LWH, Pankow JS, Boerwinkle E. "Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study." PLoS One. 2010;5(5):e10521.
Bressler J, Franceschini N, Demerath EW, Mosley TH, Folsom AR. "Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study." BMC Med Genet. 2015;16:52.
Bressler J, Fornage M, Demerath EW, et al. "Fat mass and obesity gene and cognitive decline: the Atherosclerosis Risk in Communities Study." Neurology. 2013;80(1):92-9.
Bressler J, Mosley TH, Penman A, et al. "Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study." Am J Med Genet B Neuropsychiatr Genet. 2017;174(3):269-282.
Bressler J, Folsom AR, Couper DJ, Volcik KA, Boerwinkle E. "Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study." Am J Epidemiol. 2010;171(1):14-23.
Bressler J, Fornage M, Hanis CL, et al. "The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts." BMC Med Genet. 2009;10:56.
Burke BTeevan, Köttgen A, Law A, Grams M, Baer AN, Coresh JJ. "Gout in Older Adults: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2016;71(4):536-42.
Butler AM, Yin X, Evans DS, et al. "Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts." Circ Cardiovasc Genet. 2012;5(6):639-46.
Buyske S, Wu Y, Carty CL, et al. "Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study." PLoS One. 2012;7(4):e35651.
C
C Y Ng M, Saxena R, Li J, et al. "Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study." Diabetes. 2013;62(3):965-76.
C Y Ng M, Shriner D, Chen BH, et al. "Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes." PLoS Genet. 2014;10(8):e1004517.
C Y Ng M, Graff M, Lu Y, et al. "Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium." PLoS Genet. 2017;13(4):e1006719.
Cakir B, Pankow JS, Salomaa V, et al. "Distribution of Lewis (FUT3)genotype and allele: frequencies in a biethnic United States population." Ann Hematol. 2002;81(10):558-65.
Campos M, Sun W, Yu F, et al. "Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort." Blood. 2011;117(19):5224-30.
Campos M, Buchanan A, Yu F, et al. "Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study." Blood. 2012;119(8):1929-34.
Carlson CS, Matise TC, North KE, et al. "Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study." PLoS Biol. 2013;11(9):e1001661.
Carty CL, Spencer KL, Setiawan VW, et al. "Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study." Hum Reprod. 2013;28(6):1695-706.
Carty CL, Bůžková P, Fornage M, et al. "Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study." Circ Cardiovasc Genet. 2012;5(2):210-6.
Carty CL, Keene KL, Cheng Y-C, et al. "Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans." Stroke. 2015;46(8):2063-8.
Carty CL, Bhattacharjee S, Haessler J, et al. "Analysis of metabolic syndrome components in >15 000 african americans identifies pleiotropic variants: results from the population architecture using genomics and epidemiology study." Circ Cardiovasc Genet. 2014;7(4):505-13.
Chanda P, Yuhki N, Li M, et al. "Comprehensive evaluation of imputation performance in African Americans." J Hum Genet. 2012;57(7):411-21.
Charles BA, Hsieh MM, Adeyemo AA, et al. "Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia." PLoS One. 2018;13(3):e0194400.
Chasman DI, Fuchsberger C, Pattaro C, et al. "Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function." Hum Mol Genet. 2012;21(24):5329-43.
Chatterjee NA, Giulianini F, Geelhoed B, et al. "Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization." Circulation. 2017;135(8):741-754.
Chauhan G, Adams HHH, Bis JC, et al. "Association of Alzheimer's disease GWAS loci with MRI markers of brain aging." Neurobiol Aging. 2015;36(4):1765.e7-1765.e16.
Chen Z, Tang H, Qayyum R, et al. "Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network." Hum Mol Genet. 2013;22(12):2529-38.
Cheng I, Kocarnik JM, Dumitrescu L, et al. "Pleiotropic effects of genetic risk variants for other cancers on colorectal cancer risk: PAGE, GECCO and CCFR consortia." Gut. 2014;63(5):800-7.
Cheng Y-C, Stanne TM, Giese A-K, et al. "Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2." Stroke. 2016;47(2):307-16.
Cheng C-Y, Reich D, Coresh J, et al. "Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study." Obesity (Silver Spring). 2010;18(3):563-72.
Chiang CWK, Liu C-T, Lettre G, et al. "Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms." Genetics. 2012;192(1):253-66.
Claussnitzer M, Dankel SN, Klocke B, et al. "Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms." Cell. 2014;156(1-2):343-58.
Cornelis MC, Monda KL, Yu K, et al. "Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption." PLoS Genet. 2011;7(4):e1002033.
Cornes BK, Brody JA, Nikpoor N, et al. "Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):374-382.
Cotlarciuc I, Malik R, Holliday EG, et al. "Effect of genetic variants associated with plasma homocysteine levels on stroke risk." Stroke. 2014;45(7):1920-4.
Cushman M, Cornell A, Folsom AR, et al. "Associations of the beta-fibrinogen Hae III and factor XIII Val34Leu gene variants with venous thrombosis." Thromb Res. 2007;121(3):339-45.

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