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ARIC Publications

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"Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis." Int J Epidemiol. 2012;41(5):1419-33.
Metcalf PA, Sharrett AR, Folsom AR, et al. "African American-white differences in lipids, lipoproteins, and apolipoproteins, by educational attainment, among middle-aged adults: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 1998;148(8):750-60.
Stitziel NO, Khera AV, Wang X, et al. "ANGPTL3 Deficiency and Protection Against Coronary Artery Disease." J Am Coll Cardiol. 2017;69(16):2054-2063.
Conlan MG, Folsom AR, Finch A, et al. "Antithrombin III: associations with age, race, sex and cardiovascular disease risk factors. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Thromb Haemost. 1994;72(4):551-6.
Sturgeon JD, Folsom AR, Bray MS, Boerwinkle E, Ballantyne CM. "Apolipoprotein E genotype and incident ischemic stroke: the Atherosclerosis Risk in Communities Study." Stroke. 2005;36(11):2484-6.
Gaubatz JW, Ballantyne CM, Wasserman BA, et al. "Association of circulating matrix metalloproteinases with carotid artery characteristics: the Atherosclerosis Risk in Communities Carotid MRI Study." Arterioscler Thromb Vasc Biol. 2010;30(5):1034-42.
Peloso GM, Lange LA, Varga TV, et al. "Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study." Circ Cardiovasc Genet. 2016;9(4):368-74.
Poon AK, Meyer ML, Tanaka H, et al. "Association of insulin resistance, from mid-life to late-life, with aortic stiffness in late-life: the Atherosclerosis Risk in Communities Study." Cardiovasc Diabetol. 2020;19(1):11.
Norby FL, Eryd SAdamsson, Niemeijer MN, et al. "Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium." PLoS One. 2016;11(3):e0151932.
Power MC, Rawlings A, Sharrett ARichey, et al. "Association of midlife lipids with 20-year cognitive change: A cohort study." Alzheimers Dement. 2018;14(2):167-177.
Mahmoodi BK, Cushman M, Næss IAnne, et al. "Association of Traditional Cardiovascular Risk Factors With Venous Thromboembolism: An Individual Participant Data Meta-Analysis of Prospective Studies." Circulation. 2017;135(1):7-16.
DeBoer MD, Filipp SL. "Associations of a metabolic syndrome severity score with coronary heart disease and diabetes in fasting vs. non-fasting individuals." Nutr Metab Cardiovasc Dis. 2020;30(1):92-98.
Teslovich TM, Musunuru K, Smith AV, et al. "Biological, clinical and population relevance of 95 loci for blood lipids." Nature. 2010;466(7307):707-13.
Ma L, Keinan A. "Biological knowledge-driven analysis of epistasis in human GWAS with application to lipid traits." Methods Mol Biol. 2015;1253:35-45.
Norby FL, Agarwal SK, Maclehose RF, et al. "Blood lipid levels, lipid-lowering medications, and the incidence of atrial fibrillation: the atherosclerosis risk in communities study." Circ Arrhythm Electrophysiol. 2012;5(1):155-62.
Robinson JC, Folsom AR, Nabulsi AA, Watson R, Brancati FL, Cai J. "Can postmenopausal hormone replacement improve plasma lipids in women with diabetes? The Atherosclerosis Risk in Communities Study Investigators." Diabetes Care. 1996;19(5):480-5.
Vu KN, Ballantyne CM, Hoogeveen RC, Nambi V, Volcik KA, Boerwinkle E. "Causal Role of Alcohol Consumption in an Improved Lipid Profile: The Atherosclerosis Risk in Communities (ARIC) Study." PLoS One. 2016;11(2):e0148765.
Folsom AR, McGovern PG, Nabulsi AA, et al. "Changes in plasma lipids and lipoproteins associated with starting or stopping postmenopausal hormone replacement therapy. Atherosclerosis Risk in Communities Study." Am Heart J. 1996;132(5):952-8.
Natarajan P, Pampana A, Graham SE, et al. "Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices." Nat Commun. 2021;12(1):2182.
Lamprea-Montealegre JA, Sharrett ARichey, Matsushita K, Selvin E, Szklo M. "Chronic kidney disease, lipids and apolipoproteins, and coronary heart disease: the ARIC study." Atherosclerosis. 2014;234(1):42-6.
Kou M, Ding N, Ballew SH, et al. "Conventional and Novel Lipid Measures and Risk of Peripheral Artery Disease." Arterioscler Thromb Vasc Biol. 2021;41(3):1229-1238.
Sharrett AR, Ballantyne CM, Coady SA, et al. "Coronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoproteins A-I and B, and HDL density subfractions: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2001;104(10):1108-13.
Wagenknecht L, Wasserman B, Chambless L, et al. "Correlates of carotid plaque presence and composition as measured by MRI: the Atherosclerosis Risk in Communities Study." Circ Cardiovasc Imaging. 2009;2(4):314-22.
Conlan MG, Folsom AR, Finch A, Davis CE, Sorlie P, Wu KK. "Correlation of plasma protein C levels with cardiovascular risk factors in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Thromb Haemost. 1993;70(5):762-7.
Kaptoge S, Di Angelantonio E, Pennells L, et al. "C-reactive protein, fibrinogen, and cardiovascular disease prediction." N Engl J Med. 2012;367(14):1310-20.
Natarajan P, Peloso GM, Zekavat SMaryam, et al. "Deep-coverage whole genome sequences and blood lipids among 16,324 individuals." Nat Commun. 2018;9(1):3391.
Truesdale KP, Stevens J, Cai J. "The effect of weight history on glucose and lipids: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2005;161(12):1133-43.
Miedema MD, Norby FL, Blaha MJ, Virani SS, Coresh JJ, Ballantyne CM. "Eligibility for statin therapy according to new cholesterol guidelines and prevalent use of medication to lower lipid levels in an older US Cohort: the Atherosclerosis Risk in Communities Study Cohort." JAMA Intern Med. 2015;175(1):138-40.
Mudali S, Dobs AS, Ding J, Cauley JA, Szklo M, Golden S H. "Endogenous postmenopausal hormones and serum lipids: the atherosclerosis risk in communities study." J Clin Endocrinol Metab. 2005;90(2):1202-9.
Weng L-C, Roetker NS, Lutsey PL, et al. "Evaluation of the relationship between plasma lipids and abdominal aortic aneurysm: A Mendelian randomization study." PLoS One. 2018;13(4):e0195719.
Spracklen CN, Karaderi T, Yaghootkar H, et al. "Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.
Liu DJ, Peloso GM, Yu H, et al. "Exome-wide association study of plasma lipids in >300,000 individuals." Nat Genet. 2017;49(12):1758-1766.
Wattanakit K, Folsom AR, Selvin E, Coresh J, Hirsch AT, Weatherley BD. "Kidney function and risk of peripheral arterial disease: results from the Atherosclerosis Risk in Communities (ARIC) Study." J Am Soc Nephrol. 2007;18(2):629-36.
Sharrett AR, Heiss G, Chambless LE, et al. "Metabolic and lifestyle determinants of postprandial lipemia differ from those of fasting triglycerides: The Atherosclerosis Risk In Communities (ARIC) study." Arterioscler Thromb Vasc Biol. 2001;21(2):275-81.
Burchfiel CM, Skelton TN, Andrew ME, et al. "Metabolic syndrome and echocardiographic left ventricular mass in blacks: the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2005;112(6):819-27.
Gurka MJ, Guo Y, Filipp SL. "Metabolic syndrome severity is significantly associated with future coronary heart disease in Type 2 diabetes." Cardiovasc Diabetol. 2018;17(1):17.
Power MC, Tingle JV, Reid RI, et al. "Midlife and Late-Life Vascular Risk Factors and White Matter Microstructural Integrity: The Atherosclerosis Risk in Communities Neurocognitive Study." J Am Heart Assoc. 2017;6(5).
de Vries PS, Brown MR, Bentley AR, et al. "Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions." Am J Epidemiol. 2019;188(6):1033-1054.
Bentley AR, Sung YJ, Brown MR, et al. "Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids." Nat Genet. 2019;51(4):636-648.
Noordam R, Bos MM, Wang H, et al. "Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration." Nat Commun. 2019;10(1):5121.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Everett CJ, Mainous AG, Koopman RJ, Diaz VA. "Multiple lipid scoring system for prediction of coronary heart disease risk: application to African Americans." J Natl Med Assoc. 2006;98(11):1740-5.
Brown SA, Hutchinson R, Morrisett J, et al. "Plasma lipid, lipoprotein cholesterol, and apoprotein distributions in selected US communities. The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb. 1993;13(8):1139-58.
Shahar E, Chambless LE, Rosamond WD, et al. "Plasma lipid profile and incident ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2003;34(3):623-31.
Iso H, Harada S, Shimamoto T, et al. "Polymorphism of the apolipoprotein B gene and blood lipid concentrations in Japanese and Caucasian population samples." Atherosclerosis. 1996;126(2):233-41.
Dearborn JL, Qiao Y, Guallar E, Steffen LM, Gottesman RF, Zhang Y. "Polyunsaturated fats, carbohydrates and carotid disease: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI study." Atherosclerosis. 2016;251:361-366.
Folsom AR, Wu KK, Davis CE, Conlan MG, Sorlie PD, Szklo M. "Population correlates of plasma fibrinogen and factor VII, putative cardiovascular risk factors." Atherosclerosis. 1991;91(3):191-205.
Dumitrescu L, Carty CL, Franceschini N, et al. "Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study." Ann Hum Genet. 2013;77(5):416-25.
Liao D, Cooper L, Cai J, et al. "Presence and severity of cerebral white matter lesions and hypertension, its treatment, and its control. The ARIC Study. Atherosclerosis Risk in Communities Study." Stroke. 1996;27(12):2262-70.
Folsom AR, Rosamond WD, Shahar E, et al. "Prospective study of markers of hemostatic function with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Circulation. 1999;100(7):736-42.
Justice AE, Karaderi T, Highland HM, et al. "Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution." Nat Genet. 2019;51(3):452-469.
Bhaskara S, Whitsel EA, Ballantyne CM. "Validity of self-report of lipid medication use: the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2015;242(2):625-9.