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ARIC Publications

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Zhang Y, Pletcher MJ, Vittinghoff E, et al. "Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events." JAMA Cardiol. 2021;6(12):1406-1413.
Kou M, Ding N, Ballew SH, et al. "Conventional and Novel Lipid Measures and Risk of Peripheral Artery Disease." Arterioscler Thromb Vasc Biol. 2021;41(3):1229-1238.
Bennett EE, Gianattasio KZ, Hughes TM, Mosley TH, Wong DF, Gottesman RF. "The association between midlife lipid levels and late-life brain amyloid deposition." Neurobiol Aging. 2020;92:73-74.
Li X, Li Z, Zhou H, et al. "Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale." Nat Genet. 2020;52(9):969-983.
Pokharel Y, Mouhanna F, Nambi V, et al. "ApoB, small-dense LDL-C, Lp(a), LpPLA activity, and cognitive change." Neurology. 2019;92(22):e2580-e2593.
Zhang Y, Vittinghoff E, Pletcher MJ, et al. "Associations of Blood Pressure and Cholesterol Levels During Young Adulthood With Later Cardiovascular Events." J Am Coll Cardiol. 2019;74(3):330-341.
de Vries PS, Brown MR, Bentley AR, et al. "Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions." Am J Epidemiol. 2019;188(6):1033-1054.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
Natarajan P, Peloso GM, Zekavat SMaryam, et al. "Deep-coverage whole genome sequences and blood lipids among 16,324 individuals." Nat Commun. 2018;9(1):3391.
Weng L-C, Roetker NS, Lutsey PL, et al. "Evaluation of the relationship between plasma lipids and abdominal aortic aneurysm: A Mendelian randomization study." PLoS One. 2018;13(4):e0195719.
Saeed A, Feofanova EV, Yu B, et al. "Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease." J Am Coll Cardiol. 2018;72(2):156-169.
Pankow JS, Tang W, Pankratz N, et al. "Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2017;37(3):589-597.
Morrison AC, Huang Z, Yu B, et al. "Practical Approaches for Whole-Genome Sequence Analysis of Heart- and Blood-Related Traits." Am J Hum Genet. 2017;100(2):205-215.
Jansen H, Willenborg C, Lieb W, et al. "Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation." J Rheumatol. 2017;44(1):4-10.
Do R, Willer CJ, Schmidt EM, et al. "Common variants associated with plasma triglycerides and risk for coronary artery disease." Nat Genet. 2013;45(11):1345-52.
Whelton SP, Roy P, Astor BC, Zhang L, Hoogeveen RC, Ballantyne CM. "Elevated high-sensitivity C-reactive protein as a risk marker of the attenuated relationship between serum cholesterol and cardiovascular events at older age. The ARIC Study." Am J Epidemiol. 2013;178(7):1076-84.
Folsom AR, Lutsey PL, Roetker NS, Ballantyne CM, Hoogeveen RC, Rosamond WD. "Lipoprotein-associated phospholipase A2 and venous thromboembolism: a prospective study." Thromb Res. 2013;132(1):44-6.
Dumitrescu L, Carty CL, Franceschini N, et al. "No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population." Hum Genet. 2013;132(12):1427-31.
Wu Y, Waite LL, Jackson AU, et al. "Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained." PLoS Genet. 2013;9(3):e1003379.
Carty CL, Bůžková P, Fornage M, et al. "Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study." Circ Cardiovasc Genet. 2012;5(2):210-6.
Buyske S, Wu Y, Carty CL, et al. "Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study." PLoS One. 2012;7(4):e35651.
Ma L, Brautbar A, Boerwinkle E, Sing CF, Clark AG, Keinan A. "Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations." PLoS Genet. 2012;8(5):e1002714.
Asselbergs FW, Guo Y, van Iperen EPA, et al. "Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci." Am J Hum Genet. 2012;91(5):823-38.
Musunuru K, Romaine SPR, Lettre G, et al. "Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project." PLoS One. 2012;7(5):e36473.
Voight BF, Peloso GM, Orho-Melander M, et al. "Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study." Lancet. 2012;380(9841):572-80.
Lutsey PL, Rasmussen-Torvik LJ, Pankow JS, et al. "Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study." Circ Cardiovasc Genet. 2012;5(1):73-80.
Teslovich TM, Musunuru K, Smith AV, et al. "Biological, clinical and population relevance of 95 loci for blood lipids." Nature. 2010;466(7307):707-13.
Sturgeon JD, Folsom AR, Longstreth WT, Shahar E, Rosamond WD, Cushman M. "Risk factors for intracerebral hemorrhage in a pooled prospective study." Stroke. 2007;38(10):2718-25.
Folsom AR, Peacock JM, Boerwinkle E. "Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence." Cancer Epidemiol Biomarkers Prev. 2007;16(11):2455-8.
A Sharrett R, Coady SA, Folsom AR, Couper DJ, Heiss G. "Smoking and diabetes differ in their associations with subclinical atherosclerosis and coronary heart disease-the ARIC Study." Atherosclerosis. 2004;172(1):143-9.
Shahar E, Chambless LE, Rosamond WD, et al. "Plasma lipid profile and incident ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2003;34(3):623-31.
Perova NV, Davis CE, Tao S, et al. "Multi-country comparison of plasma lipid relationship to years of schooling in men and women." Int J Epidemiol. 2001;30(2):371-9.