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ARIC Publications

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Folsom AR, Peacock JM, Boerwinkle E. "Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease." Atherosclerosis. 2009;202(1):211-5.
Shetty PB, Tang H, Feng T, et al. "Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families." Circ Cardiovasc Genet. 2015;8(1):106-13.
Garant MJ, Kao LWH, Brancati F, et al. "SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study." Diabetes. 2002;51(1):231-7.
A Sharrett R, Coady SA, Folsom AR, Couper DJ, Heiss G. "Smoking and diabetes differ in their associations with subclinical atherosclerosis and coronary heart disease-the ARIC Study." Atherosclerosis. 2004;172(1):143-9.
Hoogeveen RC, Gaubatz JW, Sun W, et al. "Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study." Arterioscler Thromb Vasc Biol. 2014;34(5):1069-77.
Cohen JC, Boerwinkle E, Mosley TH, Hobbs HH. "Sequence variations in PCSK9, low LDL, and protection against coronary heart disease." N Engl J Med. 2006;354(12):1264-72.
Folsom AR, Peacock JM, Boerwinkle E. "Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence." Cancer Epidemiol Biomarkers Prev. 2007;16(11):2455-8.
Sturgeon JD, Folsom AR, Longstreth WT, Shahar E, Rosamond WD, Cushman M. "Risk factors for intracerebral hemorrhage in a pooled prospective study." Stroke. 2007;38(10):2718-25.
Crouse JR, Goldbourt U, Evans G, et al. "Risk factors and segment-specific carotid arterial enlargement in the Atherosclerosis Risk in Communities (ARIC) cohort." Stroke. 1996;27(1):69-75.
Folsom AR, Aleksic N, Sanhueza A, Boerwinkle E. "Risk factor correlates of platelet and leukocyte markers assessed by flow cytometry in a population-based sample." Atherosclerosis. 2009;205(1):272-8.
Jansen H, Willenborg C, Lieb W, et al. "Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation." J Rheumatol. 2017;44(1):4-10.
Saeed A, Feofanova EV, Yu B, et al. "Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease." J Am Coll Cardiol. 2018;72(2):156-169.
Sharrett AR, Sorlie PD, Chambless LE, et al. "Relative importance of various risk factors for asymptomatic carotid atherosclerosis versus coronary heart disease incidence: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 1999;149(9):843-52.
Lutsey PL, Rasmussen-Torvik LJ, Pankow JS, et al. "Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study." Circ Cardiovasc Genet. 2012;5(1):73-80.
Virani SS, Catellier DJ, Pompeii LA, et al. "Relation of cholesterol and lipoprotein parameters with carotid artery plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) carotid MRI study." Atherosclerosis. 2011;219(2):596-602.
Schreiner PJ, Heiss G, Tyroler HA, Morrisett JD, Davis CE, Smith R. "Race and gender differences in the association of Lp(a) with carotid artery wall thickness. The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb Vasc Biol. 1996;16(3):471-8.
Boland LL, Folsom AR, Sorlie PD, et al. "Occurrence of unrecognized myocardial infarction in subjects aged 45 to 65 years (the ARIC study)." Am J Cardiol. 2002;90(9):927-31.
Ndumele CE, Coresh JJ, Lazo M, et al. "Obesity, subclinical myocardial injury, and incident heart failure." JACC Heart Fail. 2014;2(6):600-7.
Everett CJ, Mainous AG, Koopman RJ, Diaz VA. "Multiple lipid scoring system for prediction of coronary heart disease risk: application to African Americans." J Natl Med Assoc. 2006;98(11):1740-5.
Natarajan P, Bis JC, Bielak LF, et al. "Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis." Circ Cardiovasc Genet. 2016;9(6):511-520.
Musunuru K, Romaine SPR, Lettre G, et al. "Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project." PLoS One. 2012;7(5):e36473.
Perova NV, Davis CE, Tao S, et al. "Multi-country comparison of plasma lipid relationship to years of schooling in men and women." Int J Epidemiol. 2001;30(2):371-9.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
de Vries PS, Brown MR, Bentley AR, et al. "Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions." Am J Epidemiol. 2019;188(6):1033-1054.
Chamberlain AM, Folsom AR, Schreiner PJ, Boerwinkle E, Ballantyne CM. "Low-density lipoprotein and high-density lipoprotein cholesterol levels in relation to genetic polymorphisms and menopausal status: the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2008;200(2):322-8.
Monda KL, Ballantyne CM, North KE. "Longitudinal impact of physical activity on lipid profiles in middle-aged adults: the Atherosclerosis Risk in Communities Study." J Lipid Res. 2009;50(8):1685-91.
Ballantyne CM, Hoogeveen RC, Bang H, et al. "Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study." Arch Intern Med. 2005;165(21):2479-84.
Folsom AR, Lutsey PL, Roetker NS, Ballantyne CM, Hoogeveen RC, Rosamond WD. "Lipoprotein-associated phospholipase A2 and venous thromboembolism: a prospective study." Thromb Res. 2013;132(1):44-6.
Schreiner PJ, Morrisett JD, Sharrett AR, et al. "Lipoprotein[a] as a risk factor for preclinical atherosclerosis." Arterioscler Thromb. 1993;13(6):826-33.
Simino J, Kume R, Kraja AT, et al. "Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program." Atherosclerosis. 2014;235(1):84-93.
Asselbergs FW, Guo Y, van Iperen EPA, et al. "Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci." Am J Hum Genet. 2012;91(5):823-38.
Wagenknecht L, Wasserman B, Chambless L, et al. "Correlates of carotid plaque presence and composition as measured by MRI: the Atherosclerosis Risk in Communities Study." Circ Cardiovasc Imaging. 2009;2(4):314-22.
Kou M, Ding N, Ballew SH, et al. "Conventional and Novel Lipid Measures and Risk of Peripheral Artery Disease." Arterioscler Thromb Vasc Biol. 2021;41(3):1229-1238.
Do R, Willer CJ, Schmidt EM, et al. "Common variants associated with plasma triglycerides and risk for coronary artery disease." Nat Genet. 2013;45(11):1345-52.
Yang EY, Nambi V, Tang Z, et al. "Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study." J Am Coll Cardiol. 2009;54(25):2388-95.
Folsom AR, McGovern PG, Nabulsi AA, et al. "Changes in plasma lipids and lipoproteins associated with starting or stopping postmenopausal hormone replacement therapy. Atherosclerosis Risk in Communities Study." Am Heart J. 1996;132(5):952-8.
Holmes MV, Lange LA, Palmer T, et al. "Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
Heiss G, Sharrett AR, Barnes R, Chambless LE, Szklo M, Alzola C. "Carotid atherosclerosis measured by B-mode ultrasound in populations: associations with cardiovascular risk factors in the ARIC study." Am J Epidemiol. 1991;134(3):250-6.
Wong ND, Zhao Y, Patel R, et al. "Cardiovascular Risk Factor Targets and Cardiovascular Disease Event Risk in Diabetes: A Pooling Project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study." Diabetes Care. 2016;39(5):668-76.
"Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis." Lancet Diabetes Endocrinol. 2015;3(4):243-53.
Robinson JC, Folsom AR, Nabulsi AA, Watson R, Brancati FL, Cai J. "Can postmenopausal hormone replacement improve plasma lipids in women with diabetes? The Atherosclerosis Risk in Communities Study Investigators." Diabetes Care. 1996;19(5):480-5.
Teslovich TM, Musunuru K, Smith AV, et al. "Biological, clinical and population relevance of 95 loci for blood lipids." Nature. 2010;466(7307):707-13.
Zhang Y, Vittinghoff E, Pletcher MJ, et al. "Associations of Blood Pressure and Cholesterol Levels During Young Adulthood With Later Cardiovascular Events." J Am Coll Cardiol. 2019;74(3):330-341.
Carty CL, Bůžková P, Fornage M, et al. "Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study." Circ Cardiovasc Genet. 2012;5(2):210-6.
Colantonio LD, Bittner V, Reynolds K, et al. "Association of Serum Lipids and Coronary Heart Disease in Contemporary Observational Studies." Circulation. 2016;133(3):256-64.
Peloso GM, Auer PL, Bis JC, et al. "Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks." Am J Hum Genet. 2014;94(2):223-32.
Norby FL, Eryd SAdamsson, Niemeijer MN, et al. "Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium." PLoS One. 2016;11(3):e0151932.
Muntner P, Lee F, Astor BC. "Association of high-density lipoprotein cholesterol with coronary heart disease risk across categories of low-density lipoprotein cholesterol: the atherosclerosis risk in communities study." Am J Med Sci. 2011;341(3):173-80.
Klein R, A Sharrett R, Klein BEK, et al. "The association of atherosclerosis, vascular risk factors, and retinopathy in adults with diabetes : the atherosclerosis risk in communities study." Ophthalmology. 2002;109(7):1225-34.
Råstam L, Lindberg G, Folsom AR, Burke GL, Nilsson-Ehle P, Lundblad A. "Association between serum sialic acid concentration and carotid atherosclerosis measured by B-mode ultrasound. The ARIC Investigators. Atherosclerosis Risk in Communities Study." Int J Epidemiol. 1996;25(5):953-8.
Bennett EE, Gianattasio KZ, Hughes TM, Mosley TH, Wong DF, Gottesman RF. "The association between midlife lipid levels and late-life brain amyloid deposition." Neurobiol Aging. 2020;92:73-74.
"Are There Clinical Implications of Racial Differences in HbA1c? A Difference, to Be a Difference, Must Make a Difference." Diabetes Care. 2016;39(8):1462-7.
Volcik KA, Barkley R A, Hutchinson RG, et al. "Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants." Am J Epidemiol. 2006;164(4):342-8.
Klos K, Shimmin L, Ballantyne C, et al. "APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels." Hum Mol Genet. 2008;17(13):2039-46.