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ARIC Publications

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Chen J, Spracklen CN, Marenne G, et al. "The trans-ancestral genomic architecture of glycemic traits." Nat Genet. 2021;53(6):840-860.
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Wu B. "Sequence Kernel Association Test of Multiple Continuous Phenotypes." Genet Epidemiol. 2016;40(2):91-100.
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Wei P, Cao Y, Zhang Y, Xu Z, Kwak I-Y, Boerwinkle E. "On Robust Association Testing for Quantitative Traits and Rare Variants." G3 (Bethesda). 2016;6(12):3941-3950.
Bressler J, Kao LWH, Pankow JS, Boerwinkle E. "Risk of type 2 diabetes and obesity is differentially associated with variation in FTO in whites and African-Americans in the ARIC study." PLoS One. 2010;5(5):e10521.
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Dumitrescu L, Carty CL, Franceschini N, et al. "Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study." Ann Hum Genet. 2013;77(5):416-25.
Kraja AT, Chasman DI, North KE, et al. "Pleiotropic genes for metabolic syndrome and inflammation." Mol Genet Metab. 2014;112(4):317-38.
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Harris SE, Hagenaars SP, Davies G, et al. "Molecular genetic contributions to self-rated health." Int J Epidemiol. 2017;46(3):994-1009.
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Wild PS, Felix JF, Schillert A, et al. "Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function." J Clin Invest. 2017;127(5):1798-1812.
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Auer PL, Johnsen JM, Johnson AD, et al. "Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project." Am J Hum Genet. 2012;91(5):794-808.
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Franceschini N, Fox E, Zhang Z, et al. "Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations." Am J Hum Genet. 2013;93(3):545-54.
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Avery CL, Sethupathy P, Buyske S, et al. "Fine-mapping and initial characterization of QT interval loci in African Americans." PLoS Genet. 2012;8(8):e1002870.
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Avery CL, Sitlani CM, Arking DE, et al. "Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval." Pharmacogenomics J. 2014;14(1):6-13.
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Wuttke M, Li Y, Li M, et al. "A catalog of genetic loci associated with kidney function from analyses of a million individuals." Nat Genet. 2019;51(6):957-972.
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Ma L, Keinan A. "Biological knowledge-driven analysis of epistasis in human GWAS with application to lipid traits." Methods Mol Biol. 2015;1253:35-45.
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Peloso GM, Lange LA, Varga TV, et al. "Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study." Circ Cardiovasc Genet. 2016;9(4):368-74.
Cheng C-Y, Reich D, Haiman CA, et al. "African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts." PLoS One. 2012;7(3):e32840.