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ARIC Publications

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2018
Norby FL, Chen LYee, Soliman EZ, Gottesman RF, Mosley TH. "Association of left ventricular hypertrophy with cognitive decline and dementia risk over 20 years: The Atherosclerosis Risk In Communities-Neurocognitive Study (ARIC-NCS)." Am Heart J. 2018;204:58-67.
Garg PK, Bartz TM, Norby FL, et al. "Association of lipoprotein-associated phospholipase A and risk of incident atrial fibrillation: Findings from 3 cohorts." Am Heart J. 2018;197:62-69.
Bekwelem W, Norby FL, Agarwal SK, Matsushita K, Coresh JJ, Alonso A. "Association of Peripheral Artery Disease With Incident Atrial Fibrillation: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(8).
Lin H, van Setten J, Smith AV, et al. "Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval." Circ Genom Precis Med. 2018;11(5):e002037.
Macri V, Brody JA, Arking DE, et al. "Common Coding Variants in Are Associated With the Nav1.8 Late Current and Cardiac Conduction." Circ Genom Precis Med. 2018;11(5):e001663.
Sood SL, Cheng D, Ragni M, et al. "A cross-sectional analysis of cardiovascular disease in the hemophilia population." Blood Adv. 2018;2(11):1325-1333.
Prins BP, Mead TJ, Brody JA, et al. "Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6." Genome Biol. 2018;19(1):87.
Bihlmeyer NA, Brody JA, Smith A V, et al. "ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals." Circ Genom Precis Med. 2018;11(1):e001758.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Fifteen-Year Trends in Management and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Among Black and White Patients: The ARIC Community Surveillance Study, 2000-2014." J Am Heart Assoc. 2018;7(19):e010203.
Napier MD, Franceschini N, Gondalia R, et al. "Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy." Sci Rep. 2018;8(1):5675.
Tereshchenko LG, Sotoodehnia N, Sitlani CM, et al. "Genome-Wide Associations of Global Electrical Heterogeneity ECG Phenotype: The ARIC (Atherosclerosis Risk in Communities) Study and CHS (Cardiovascular Health Study)." J Am Heart Assoc. 2018;7(8).
Biering-Sørensen T, Kabir M, Waks JW, et al. "Global ECG Measures and Cardiac Structure and Function: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Arrhythm Electrophysiol. 2018;11(3):e005961.
Seyerle AA, Sitlani CM, Noordam R, et al. "Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology." Pharmacogenomics J. 2018;18(2):215-226.
van Setten J, Brody JA, Jamshidi Y, et al. "PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity." Nat Commun. 2018;9(1):2904.
Aeschbacher S, O'Neal WT, Krisai P, et al. "Relationship between QRS duration and incident atrial fibrillation." Int J Cardiol. 2018;266:84-88.
Qureshi WT, Zhang Z-M, Chang PP, Rosamond WD, Kitzman DW, Wagenknecht LE. "Silent Myocardial Infarction and Long-Term Risk of Heart Failure: The ARIC Study." J Am Coll Cardiol. 2018;71(1):1-8.
2017
Maheshwari A, Norby FL, Soliman EZ, et al. "Abnormal P-Wave Axis and Ischemic Stroke: The ARIC Study (Atherosclerosis Risk In Communities)." Stroke. 2017;48(8):2060-2065.
O'Neal WT, Singleton MJ, Roberts JD, et al. "Association Between QT-Interval Components and Sudden Cardiac Death: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Arrhythm Electrophysiol. 2017;10(10).
Aronis KN, Zhao D, Hoogeveen RC, et al. "Associations of Lipoprotein(a) Levels With Incident Atrial Fibrillation and Ischemic Stroke: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2017;6(12).
Agarwal SK, Norby FL, Whitsel EA, et al. "Cardiac Autonomic Dysfunction and Incidence of Atrial Fibrillation: Results From 20 Years Follow-Up." J Am Coll Cardiol. 2017;69(3):291-299.
Alburikan KA, Aldemerdash A, Savitz ST, et al. "Contribution of medications and risk factors to QTc interval lengthening in the atherosclerosis risk in communities (ARIC) study." J Eval Clin Pract. 2017;23(6):1274-1280.
Patel S, Kwak L, Agarwal SK, Tereshchenko LG, Coresh JJ, Soliman EZ. "Counterclockwise and Clockwise Rotation of QRS Transitional Zone: Prospective Correlates of Change and Time-Varying Associations With Cardiovascular Outcomes." J Am Heart Assoc. 2017;6(11).
Nguyen KT, Vittinghoff E, Dewland TA, et al. "Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community." J Am Heart Assoc. 2017;6(8).
Aro AL, Reinier K, Rusinaru C, et al. "Electrical risk score beyond the left ventricular ejection fraction: prediction of sudden cardiac death in the Oregon Sudden Unexpected Death Study and the Atherosclerosis Risk in Communities Study." Eur Heart J. 2017;38(40):3017-3025.
Roberts JD, Soliman EZ, Alonso A, Vittinghoff E, Chen LYee, Loehr LR. "Electrocardiographic intervals associated with incident atrial fibrillation: Dissecting the QT interval." Heart Rhythm. 2017;14(5):654-660.
Zhang Z-M, Rautaharju PM, Prineas RJ, Tereshchenko L. "Electrocardiographic QRS-T angle and the risk of incident silent myocardial infarction in the Atherosclerosis Risk in Communities study." J Electrocardiol. 2017;50(5):661-666.
Avery CL, Wassel CL, Richard MA, et al. "Fine mapping of QT interval regions in global populations refines previously identified QT interval loci and identifies signals unique to African and Hispanic descent populations." Heart Rhythm. 2017;14(4):572-580.
Fashanu OE, Norby FL, Aguilar D, et al. "Galectin-3 and incidence of atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2017;192:19-25.
Smith JW, O'Neal WT, M Shoemaker B, Chen LYee, Alonso A, S Whalen P. "PR-Interval Components and Atrial Fibrillation Risk (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(3):466-472.
Maheshwari A, Norby FL, Soliman EZ, et al. "Relation of Prolonged P-Wave Duration to Risk of Sudden Cardiac Death in the General Population (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(9):1302-1306.
Soliman EZ, Zhang Z-M, Chen LYee, Tereshchenko LG, Arking D. "Usefulness of Maintaining a Normal Electrocardiogram Over Time for Predicting Cardiovascular Health." Am J Cardiol. 2017;119(2):249-255.
2016
O'Neal WT, Kamel H, Zhang Z-M, Chen LYee, Alonso A. "Advanced interatrial block and ischemic stroke: The Atherosclerosis Risk in Communities Study." Neurology. 2016;87(4):352-6.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Bundle branch blocks and the risk of mortality in the Atherosclerosis Risk in Communities study." J Cardiovasc Med (Hagerstown). 2016;17(6):411-7.
O'Neal WT, Zhang Z-M, Loehr LR, Chen LYee, Alonso A. "Electrocardiographic Advanced Interatrial Block and Atrial Fibrillation Risk in the General Population." Am J Cardiol. 2016;117(11):1755-9.
O'Neal WT, Wang YGrace, Wu H-T, et al. "Electrocardiographic J Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2016;118(6):811-815.
Evans DS, Avery CL, Nalls MA, et al. "Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans." Hum Mol Genet. 2016;25(19):4350-4368.
Waks JW, Sitlani CM, Soliman EZ, et al. "Global Electric Heterogeneity Risk Score for Prediction of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies." Circulation. 2016;133(23):2222-34.
Maheshwari A, Norby FL, Soliman EZ, Adabag S, Whitsel EA, Alonso A. "Low Heart Rate Variability in a 2-Minute Electrocardiogram Recording Is Associated with an Increased Risk of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities Study." PLoS One. 2016;11(8):e0161648.
Gori M, Gupta DK, Claggett B, et al. "Natriuretic Peptide and High-Sensitivity Troponin for Cardiovascular Risk Prediction in Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):677-85.
Kapoor A, Bakshy K, Xu L, et al. "Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
Verweij N, Mateo Leach I, Isaacs A, et al. "Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram." Hum Mol Genet. 2016;25(10):2093-2103.
2015
Soliman EZ, Norby FL, O'Neal WT, et al. "Atrial Fibrillation and Risk of ST-Segment-Elevation Versus Non-ST-Segment-Elevation Myocardial Infarction: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2015;131(21):1843-50.
Waks JW, Soliman EZ, Henrikson CA, et al. "Beat-to-beat spatiotemporal variability in the T vector is associated with sudden cardiac death in participants without left ventricular hypertrophy: the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2015;4(1):e001357.
Kamel H, O'Neal WT, Okin PM, Loehr LR, Alonso A. "Electrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities study." Ann Neurol. 2015;78(5):670-8.
Rautaharju PM, Zhang Z-M, Haisty WK, Kucharska-Newton AMaria, Rosamond WD. "Electrocardiographic repolarization-related predictors of coronary heart disease and sudden cardiac deaths in men and women with cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study." J Electrocardiol. 2015;48(1):101-11.
Okwuosa TM, Soliman EZ, Norby FL, Williams KA, Alonso A. "Left ventricular hypertrophy and cardiovascular disease risk prediction and reclassification in blacks and whites: the Atherosclerosis Risk in Communities Study." Am Heart J. 2015;169(1):155-61.e5.
Shah AM, Claggett B, Sweitzer NK, et al. "Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone." Circulation. 2015;132(5):402-14.
Magnani JW, Zhu L, Norby FL, et al. "P-wave indices and atrial fibrillation: cross-cohort assessments from the Framingham Heart Study (FHS) and Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2015;169(1):53-61.e1.
E Estes H, Zhang Z-M, Li Y, Tereschenko LG. "The Romhilt-Estes left ventricular hypertrophy score and its components predict all-cause mortality in the general population." Am Heart J. 2015;170(1):104-9.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Ventricular conduction defects and the risk of incident heart failure in the Atherosclerosis Risk in Communities (ARIC) Study." J Card Fail. 2015;21(4):307-12.
Zhang Z-M, Rautaharju PM, Prineas RJ, Whitsel EA, Tereshchenko L. "A wide QRS/T angle in bundle branch blocks is associated with increased risk for coronary heart disease and all-cause mortality in the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2015;48(4):672-7.
2014
Avery CL, Sitlani CM, Arking DE, et al. "Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval." Pharmacogenomics J. 2014;14(1):6-13.
Tereshchenko LG, Henrikson CA, Sotoodehnia N, et al. "Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the Atherosclerosis Risk in Communities (ARIC) study." J Am Heart Assoc. 2014;3(6):e001387.
Kapoor A, Sekar RB, Hansen NF, et al. "An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval." Am J Hum Genet. 2014;94(6):854-69.
Arking DE, Pulit SL, Crotti L, et al. "Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization." Nat Genet. 2014;46(8):826-36.
Rautaharju PM, Zhang Z-M, Haisty WK, et al. "Race- and sex-associated differences in rate-adjusted QT, QTpeak, ST elevation and other regional measures of repolarization: the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2014;47(3):342-50.
Qureshi W, Soliman EZ, Solomon SD, et al. "Risk factors for atrial fibrillation in patients with normal versus dilated left atrium (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2014;114(9):1368-72.
Gellert KS, Rautaharju P, Snyder ML, Whitsel EA, Matsushita K, Heiss G. "Short-term repeatability of electrocardiographic Tpeak-Tend and QT intervals." J Electrocardiol. 2014;47(3):356-61.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Usefulness of electrocardiographic QRS/T angles with versus without bundle branch blocks to predict heart failure (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2014;114(3):412-8.
2012
Avery CL, Sethupathy P, Buyske S, et al. "Fine-mapping and initial characterization of QT interval loci in African Americans." PLoS Genet. 2012;8(8):e1002870.
J Smith G, Avery CL, Evans DS, et al. "Impact of ancestry and common genetic variants on QT interval in African Americans." Circ Cardiovasc Genet. 2012;5(6):647-55.
Butler AM, Yin X, Evans DS, et al. "Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts." Circ Cardiovasc Genet. 2012;5(6):639-46.
Magnani JW, Lopez FL, Soliman EZ, Maclehose RF, Crow RS, Alonso A. "P wave indices, obesity, and the metabolic syndrome: the atherosclerosis risk in communities study." Obesity (Silver Spring). 2012;20(3):666-72.
Zhang Z-M, Prineas RJ, Soliman EZ, Baggett C. "Prognostic significance of serial Q/ST-T changes by the Minnesota Code and Novacode in the Atherosclerosis Risk in Communities (ARIC) study." Eur J Prev Cardiol. 2012;19(6):1430-6.
Agarwal SK, Simpson RJ, Rautaharju P, et al. "Relation of ventricular premature complexes to heart failure (from the Atherosclerosis Risk In Communities [ARIC] Study)." Am J Cardiol. 2012;109(1):105-9.
Hermida J, Norby FL, Montes R, Matsushita K, Astor BC. "Usefulness of high-sensitivity C-reactive protein to predict mortality in patients with atrial fibrillation (from the Atherosclerosis Risk In Communities [ARIC] Study)." Am J Cardiol. 2012;109(1):95-9.

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