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ARIC Publications

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Journal Article
Liu Y, Chen S, Li Z, Morrison AC, Boerwinkle E. "ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies." Am J Hum Genet. 2019;104(3):410-421.
Chambless LE, Davis V. "Analysis of associations with change in a multivariate outcome variable when baseline is subject to measurement error." Stat Med. 2003;22(7):1041-67.
Peloso GM, Lange LA, Varga TV, et al. "Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study." Circ Cardiovasc Genet. 2016;9(4):368-74.
Ray D, Li X, Pan W, Pankow JS. "A Bayesian Partitioning Model for the Detection of Multilocus Effects in Case-Control Studies." Hum Hered. 2015;79(2):69-79.
Avery CL, Sitlani CM, Arking DE, et al. "Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval." Pharmacogenomics J. 2014;14(1):6-13.
Li X, Li Z, Zhou H, et al. "Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale." Nat Genet. 2020;52(9):969-983.
Wu B, Guan W. "On Efficient and Accurate Calculation of Significance P-Values for Sequence Kernel Association Testing of Variant Set." Ann Hum Genet. 2016;80(2):123-35.
Barrett JK, Huille R, Parker R, Yano Y. "Estimating the association between blood pressure variability and cardiovascular disease: An application using the ARIC Study." Stat Med. 2019;38(10):1855-1868.
Huang J, Wang K, Wei P, et al. "FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics." Genetics. 2016;202(3):919-29.
Huang H, Chanda P, Alonso A, Bader JS, Arking DE. "Gene-based tests of association." PLoS Genet. 2011;7(7):e1002177.
Sitlani CM, Rice KM, Lumley T, et al. "Generalized estimating equations for genome-wide association studies using longitudinal phenotype data." Stat Med. 2015;34(1):118-30.
Cheng Y-C, Stanne TM, Giese A-K, et al. "Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2." Stroke. 2016;47(2):307-16.
Sennblad B, Basu S, Mazur J, et al. "Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels." Hum Mol Genet. 2017;26(3):637-649.
Bijari PB, Antiga L, Gallo D, Wasserman BA. "Improved prediction of disturbed flow via hemodynamically-inspired geometric variables." J Biomech. 2012;45(9):1632-7.
Kim S, Cai J. "Improving the efficiency of estimation in the additive hazards model for stratified case-cohort design with multiple diseases." Stat Med. 2016;35(2):282-93.
Wu C, Demerath EW, Pankow JS, et al. "Imputation of missing covariate values in epigenome-wide analysis of DNA methylation data." Epigenetics. 2016;11(2):132-9.
Liu J, Carnero-Montoro E, van Dongen J, et al. "An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis." Nat Commun. 2019;10(1):2581.
Kang S, Cai J. "Marginal additive hazards model for case-cohort studies with multiple disease outcomes: an application to the Atherosclerosis Risk in Communities (ARIC) study." Biostatistics. 2013;14(1):28-41.
Hu Y-J, Berndt SI, Gustafsson S, et al. "Meta-analysis of gene-level associations for rare variants based on single-variant statistics." Am J Hum Genet. 2013;93(2):236-48.
Shi G, Boerwinkle E, Morrison AC, Gu CC, Chakravarti A, Rao DC. "Mining gold dust under the genome wide significance level: a two-stage approach to analysis of GWAS." Genet Epidemiol. 2011;35(2):111-8.
Rawlings AMonica, Sang Y, Sharrett ARichey, et al. "Multiple imputation of cognitive performance as a repeatedly measured outcome." Eur J Epidemiol. 2017;32(1):55-66.
Keogh RH, Seaman SR, Bartlett JW. "Multiple imputation of missing data in nested case-control and case-cohort studies." Biometrics. 2018;74(4):1438-1449.
Zhou Q, Cai J. "Outcome-dependent sampling with interval-censored failure time data." Biometrics. 2018;74(1):58-67.
Zhao J, Zhu Y, Boerwinkle E. "Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
Wei P, Cao Y, Zhang Y, Xu Z, Kwak I-Y, Boerwinkle E. "On Robust Association Testing for Quantitative Traits and Rare Variants." G3 (Bethesda). 2016;6(12):3941-3950.
Wang W, Wang W, Mosley TH. "A SAS macro for the joint modeling of longitudinal outcomes and multiple competing risk dropouts." Comput Methods Programs Biomed. 2017;138:23-30.
Wu B, Pankow JS. "Sequence Kernel Association Analysis of Rare Variant Set Based on the Marginal Regression Model for Binary Traits." Genet Epidemiol. 2015;39(6):399-405.
Chambless LE, Cummiskey CP, Cui G. "Several methods to assess improvement in risk prediction models: extension to survival analysis." Stat Med. 2011;30(1):22-38.
Wu B. "Statistical methods for association tests of multiple continuous traits in genome-wide association studies." Ann Hum Genet. 2015;79(4):282-93.
Ray D, Pankow JS. "USAT: A Unified Score-Based Association Test for Multiple Phenotype-Genotype Analysis." Genet Epidemiol. 2016;40(1):20-34.