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ARIC Publications

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Zhou Z, Yu F, Buchanan A, et al. "Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts." PLoS One. 2014;9(1):e84810.
Zhao J, Zhu Y, Boerwinkle E. "Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
Zhao D, Post WS, Blasco-Colmenares E, et al. "Racial Differences in Sudden Cardiac Death." Circulation. 2019;139(14):1688-1697.
Zhang Z-M, Rautaharju PM, Prineas RJ, et al. "Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(22):2141-8.
Zakai NA, McClure LA, Judd SE, Safford MM, Folsom AR, Lutsey PL. "Racial and regional differences in venous thromboembolism in the United States in 3 cohorts." Circulation. 2014;129(14):1502-9.
Yu Z, Rebholz CM, Wong E, Chen Y, Matsushita K, Coresh JJ. "Association Between Hypertension and Kidney Function Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2019;74(3):310-319.
Yu B, Li AH, Muzny D, et al. "Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease." Circ Cardiovasc Genet. 2015;8(2):351-5.
Yu B, Pulit SL, Hwang S-J, et al. "Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk." Circ Cardiovasc Genet. 2016;9(1):64-70.
Yu B, Li AH, Metcalf GA, et al. "Loss-of-function variants influence the human serum metabolome." Sci Adv. 2016;2(8):e1600800.
Yoneyama S, Yao J, Guo X, et al. "Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations." Int J Obes (Lond). 2017;41(2):324-331.
Yoneyama S, Guo Y, Lanktree MB, et al. "Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations." Hum Mol Genet. 2014;23(9):2498-510.
Yao L, Folsom AR, Pankow JS, et al. "Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study." J Hypertens. 2016;34(2):196-203.
Yano Y, Griswold M, Wang W, et al. "Long-Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study." J Am Heart Assoc. 2018;7(15):e009578.
Wyss AB, Sofer T, Lee MKyeong, et al. "Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function." Nat Commun. 2018;9(1):2976.
Wuttke M, Li Y, Li M, et al. "A catalog of genetic loci associated with kidney function from analyses of a million individuals." Nat Genet. 2019;51(6):957-972.
Wood AR, Esko T, Yang J, et al. "Defining the role of common variation in the genomic and biological architecture of adult human height." Nat Genet. 2014;46(11):1173-86.
Winkler TW, Justice AE, Graff M, et al. "The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2015;11(10):e1005378.
B Windham G, Harrison KL, Lirette ST, et al. "Relationship Between Midlife Cardiovascular Health and Late-Life Physical Performance: The ARIC Study." J Am Geriatr Soc. 2017;65(5):1012-1018.
B Windham G, Griswold ME, Wang W, et al. "The Importance of Mid-to-Late-Life Body Mass Index Trajectories on Late-Life Gait Speed." J Gerontol A Biol Sci Med Sci. 2017;72(8):1130-1136.
Whitman IR, Vittinghoff E, Defilippi CR, et al. "NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure." J Am Heart Assoc. 2019;8(7):e010868.
West NA, Tingle JV, Simino J, Selvin E, Bressler J. "The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity." Alzheimer Dis Assoc Disord. 2018;32(2):131-136.
Wessel J, Chu AY, Willems SM, et al. "Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility." Nat Commun. 2015;6:5897.
Weng L-C, Cushman M, Pankow JS, Basu S, Boerwinkle E, Folsom AR. "A genetic association study of activated partial thromboplastin time in European Americans and African Americans: the ARIC Study." Hum Mol Genet. 2015;24(8):2401-8.
Wen CPang, Matsushita K, Coresh JJ, et al. "Relative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar." Kidney Int. 2014;86(4):819-27.
Wei GS, Coady SA, Reis JP, et al. "Duration and Degree of Weight Gain and Incident Diabetes in Younger Versus Middle-Aged Black and White Adults: ARIC, CARDIA, and the Framingham Heart Study." Diabetes Care. 2015;38(11):2042-9.
Wang S, Fashanu OE, Zhao D, et al. "Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20 Years (from the Atherosclerosis Risk in Communities [ARIC] Study)." Am J Cardiol. 2019;123(2):334-340.
Walker KA, Hoogeveen RC, Folsom AR, et al. "Midlife systemic inflammatory markers are associated with late-life brain volume: The ARIC study." Neurology. 2017;89(22):2262-2270.
Walker KA, Power MC, Hoogeveen RC, et al. "Midlife Systemic Inflammation, Late-Life White Matter Integrity, and Cerebral Small Vessel Disease: The Atherosclerosis Risk in Communities Study." Stroke. 2017;48(12):3196-3202.
Tragante V, Barnes MR, Ganesh SK, et al. "Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci." Am J Hum Genet. 2014;94(3):349-60.
Tin A, Grams ME, Maruthur NM, et al. "Hemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(5):784-90.
Tin A, Köttgen A, Folsom AR, et al. "Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study." BMC Genet. 2015;16:56.
Tin A, Balakrishnan P, Beaty TH, Boerwinkle E, Hoogeveen RC, Young JH. "GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2016;33(7):968-75.
Crosby J, Peloso GM, Auer PL, et al. "Loss-of-function mutations in APOC3, triglycerides, and coronary disease." N Engl J Med. 2014;371(1):22-31.
Teumer A, Chaker L, Groeneweg S, et al. "Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation." Nat Commun. 2018;9(1):4455.
Tang W, Cushman M, Green D, et al. "Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans." Am J Hematol. 2015;90(6):534-40.
Tang W, Yao L, Roetker NS, et al. "Lifetime Risk and Risk Factors for Abdominal Aortic Aneurysm in a 24-Year Prospective Study: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2016;36(12):2468-2477.
Takiar R, Lutsey PL, Zhao D, et al. "The associations of 25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms, and race with risk of incident fracture-related hospitalization: Twenty-year follow-up in a bi-ethnic cohort (the ARIC Study)." Bone. 2015;78:94-101.
Tabor HK, Auer PL, Jamal SM, et al. "Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results." Am J Hum Genet. 2014;95(2):183-93.
Sumida K, Kwak L, Grams ME, et al. "Lung Function and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2017;70(5):675-685.
Stevens J, Erber-Oakkar E, Cui Z, Cai J, Virani SS, Di Angelantonio E. "Cardiovascular disease risk by assigned treatment using the 2013 and 1998 obesity guidelines." Obesity (Silver Spring). 2016;24(7):1554-60.
Spracklen CN, Karaderi T, Yaghootkar H, et al. "Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.
Song J, Chen F, Campos M, et al. "Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects." PLoS One. 2015;10(8):e0132626.
Smith CE, Follis JL, Dashti HS, et al. "Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent." Mol Nutr Food Res. 2018;62(3).
Smith JW, O'Neal WT, M Shoemaker B, Chen LYee, Alonso A, S Whalen P. "PR-Interval Components and Atrial Fibrillation Risk (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(3):466-472.
Smith JA, Zhao W, Yasutake K, et al. "Gene-by-Psychosocial Factor Interactions Influence Diastolic Blood Pressure in European and African Ancestry Populations: Meta-Analysis of Four Cohort Studies." Int J Environ Res Public Health. 2017;14(12).
Simino J, Wang Z, Bressler J, et al. "Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study." PLoS One. 2017;12(7):e0180046.
Simino J, Kume R, Kraja AT, et al. "Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program." Atherosclerosis. 2014;235(1):84-93.
Sim X, Jensen RA, M Ikram K, et al. "Genetic loci for retinal arteriolar microcirculation." PLoS One. 2013;8(6):e65804.
Shah AM, Cheng S, Skali H, et al. "Rationale and design of a multicenter echocardiographic study to assess the relationship between cardiac structure and function and heart failure risk in a biracial cohort of community-dwelling elderly persons: the Atherosclerosis Risk in Communities stud." Circ Cardiovasc Imaging. 2014;7(1):173-81.
"Are There Clinical Implications of Racial Differences in HbA1c? A Difference, to Be a Difference, Must Make a Difference." Diabetes Care. 2016;39(8):1462-7.
Seidelmann SB, Feofanova E, Yu B, et al. "Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk." J Am Coll Cardiol. 2018;72(15):1763-1773.
Seidelmann SB, Vardeny O, Claggett B, et al. "An Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality." J Am Heart Assoc. 2017;6(4).
Scott RA, Scott LJ, Mägi R, et al. "An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans." Diabetes. 2017;66(11):2888-2902.
Schneider ALC, Lutsey PL, Selvin E, et al. "Vitamin D, vitamin D binding protein gene polymorphisms, race and risk of incident stroke: the Atherosclerosis Risk in Communities (ARIC) study." Eur J Neurol. 2015;22(8):1220-7.
Schneider ALC, Sharrett ARichey, Gottesman RF, et al. "Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study." Alzheimer Dis Assoc Disord. 2015;29(1):32-44.
Schneider ALC, Lutsey PL, Alonso A, et al. "Vitamin D and cognitive function and dementia risk in a biracial cohort: the ARIC Brain MRI Study." Eur J Neurol. 2014;21(9):1211-8, e69-70.
Schick UM, Auer PL, Bis JC, et al. "Association of exome sequences with plasma C-reactive protein levels in >9000 participants." Hum Mol Genet. 2015;24(2):559-71.
Scharpf RB, Mireles L, Yang Q, et al. "Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations." BMC Genet. 2014;15:81.
Savoca MR, Steffen LM, Bertoni AG. "From Neighborhood to Genome: Three Decades of Nutrition-Related Research from the Atherosclerosis Risk in Communities Study." J Acad Nutr Diet. 2017;117(12):1881-1886.e10.
Sanders AE, Divaris K, Naorungroj S, Heiss G. "Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study." J Clin Periodontol. 2015;42(1):12-20.
Salfati E, Morrison AC, Boerwinkle E. "Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC)." PLoS One. 2015;10(7):e0133031.
Sahli MW, Mares JA, Meyers KJ, et al. "Dietary Intake of Lutein and Diabetic Retinopathy in the Atherosclerosis Risk in Communities Study (ARIC)." Ophthalmic Epidemiol. 2016;23(2):99-108.
Saeed A, Sun W, Agarwala A, et al. "Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
Sabater-Lleal M, Huang J, Chasman D, et al. "Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease." Circulation. 2013;128(12):1310-24.
Rooney MR, Pankow JS, Sibley SD, Selvin E, Reis JP, Michos ED. "Serum calcium and incident type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Am J Clin Nutr. 2016;104(4):1023-1029.
Roetker NS, Armasu SM, Pankow JS, et al. "Taller height as a risk factor for venous thromboembolism: a Mendelian randomization meta-analysis." J Thromb Haemost. 2017;15(7):1334-1343.
Robinson-Cohen C, Bartz TM, Lai D, et al. "Genetic Variants Associated with Circulating Fibroblast Growth Factor 23." J Am Soc Nephrol. 2018;29(10):2583-2592.
Roberts JD, Hu D, Heckbert SR, et al. "Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals." JAMA Cardiol. 2016;1(4):442-50.
Reis JP, Selvin E, Pankow JS, Michos ED, Rebholz CM. "Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Metab. 2016;42(3):162-9.
Reis JP, Michos ED, Selvin E, Pankow JS. "Race, vitamin D-binding protein gene polymorphisms, 25-hydroxyvitamin D, and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2015;101(6):1232-40.
Rawlings AM, Sharrett ARichey, Schneider ALC, et al. "Diabetes in midlife and cognitive change over 20 years: a cohort study." Ann Intern Med. 2014;161(11):785-93.
Rautaharju PM, Zhang Z-M, Haisty WK, et al. "Race- and sex-associated differences in rate-adjusted QT, QTpeak, ST elevation and other regional measures of repolarization: the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2014;47(3):342-50.
Rapson IR, Michos ED, Alonso A, Hirsch AT, Matsushita K, Reis JP. "Serum 25-hydroxyvitamin D is associated with incident peripheral artery disease among white and black adults in the ARIC study cohort." Atherosclerosis. 2017;257:123-129.
Raffield LM, Iyengar AK, Wang B, et al. "Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts." Am J Hum Genet. 2020;106(1):112-120.
Qiao Y, Suri FK, Zhang Y, et al. "Racial Differences in Prevalence and Risk for Intracranial Atherosclerosis in a US Community-Based Population." JAMA Cardiol. 2017;2(12):1341-1348.
Qi Q, Kilpeläinen TO, Downer MK, et al. "FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals." Hum Mol Genet. 2014;23(25):6961-72.