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ARIC Publications

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Journal Article
Michos ED, Misialek JR, Selvin E, Folsom AR, Pankow JS, Post WS. "25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms and incident coronary heart disease among whites and blacks: The ARIC study." Atherosclerosis. 2015;241(1):12-7.
Nambi V, Boerwinkle E, Lawson K, et al. "The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2012;222(1):135-7.
Houston DK, Stevens J, Cai J. "Abdominal fat distribution and functional limitations and disability in a biracial cohort: the Atherosclerosis Risk in Communities Study." Int J Obes (Lond). 2005;29(12):1457-63.
Huxley RR, Lopez FL, Folsom AR, et al. "Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2011;123(14):1501-8.
Hozawa A, Folsom AR, A Sharrett R, Chambless LE. "Absolute and attributable risks of cardiovascular disease incidence in relation to optimal and borderline risk factors: comparison of African American with white subjects--Atherosclerosis Risk in Communities Study." Arch Intern Med. 2007;167(6):573-9.
Amendola LM, Dorschner MO, Robertson PD, et al. "Actionable exomic incidental findings in 6503 participants: challenges of variant classification." Genome Res. 2015;25(3):305-15.
Morrison AC, Bray MS, Folsom AR, Boerwinkle E. "ADD1 460W allele associated with cardiovascular disease in hypertensive individuals." Hypertension. 2002;39(6):1053-7.
Millen AE, Sahli MW, Nie J, et al. "Adequate vitamin D status is associated with the reduced odds of prevalent diabetic retinopathy in African Americans and Caucasians." Cardiovasc Diabetol. 2016;15(1):128.
Onyeaghala G, Lintelmann AK, Joshu CE, et al. "Adherence to the World Cancer Research Fund/American Institute for Cancer Research cancer prevention guidelines and colorectal cancer incidence among African Americans and whites: The Atherosclerosis Risk in Communities study." Cancer. 2020;126(5):1041-1050.
Duncan BB, Schmidt M I, Pankow JS, et al. "Adiponectin and the development of type 2 diabetes: the atherosclerosis risk in communities study." Diabetes. 2004;53(9):2473-8.
Cheng C-Y, Reich D, Coresh J, et al. "Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study." Obesity (Silver Spring). 2010;18(3):563-72.
Metcalf PA, Sharrett AR, Folsom AR, et al. "African American-white differences in lipids, lipoproteins, and apolipoproteins, by educational attainment, among middle-aged adults: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 1998;148(8):750-60.
Cheng C-Y, Reich D, Haiman CA, et al. "African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts." PLoS One. 2012;7(3):e32840.
Dreyfus JG, Lutsey PL, Huxley R, et al. "Age at menarche and risk of type 2 diabetes among African-American and white women in the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2012;55(9):2371-80.
Cheung N, Shankar A, Klein R, Folsom AR, Couper DJ, Wong T Y. "Age-related macular degeneration and cancer mortality in the atherosclerosis risk in communities study." Arch Ophthalmol. 2007;125(9):1241-7.
Li J, Agarwal SK, Alonso A, et al. "Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2014;129(9):971-80.
Eigenbrodt ML, Mosley TH, Hutchinson RG, Watson RL, Chambless LE, Szklo M. "Alcohol consumption with age: a cross-sectional and longitudinal study of the Atherosclerosis Risk in Communities (ARIC) study, 1987-1995." Am J Epidemiol. 2001;153(11):1102-11.
Ding J, Eigenbrodt ML, Mosley TH, et al. "Alcohol intake and cerebral abnormalities on magnetic resonance imaging in a community-based population of middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2004;35(1):16-21.
Raffield LM, Iyengar AK, Wang B, et al. "Allelic Heterogeneity at the CRP Locus Identified by Whole-Genome Sequencing in Multi-ancestry Cohorts." Am J Hum Genet. 2020;106(1):112-120.
Fu W, O'Connor TD, Jun G, et al. "Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants." Nature. 2013;493(7431):216-20.
Direk N, Williams S, Smith JA, et al. "An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype." Biol Psychiatry. 2017;82(5):322-329.
Kucharska-Newton AMaria, Williams JE, Chang PP, Stearns SC, Sueta CA, Blecker SB. "Anger proneness, gender, and the risk of heart failure." J Card Fail. 2014;20(12):1020-6.
Williams JE, Paton CC, Siegler IC, Eigenbrodt ML, Nieto FJ, Tyroler HA. "Anger proneness predicts coronary heart disease risk: prospective analysis from the atherosclerosis risk in communities (ARIC) study." Circulation. 2000;101(17):2034-9.
Kshirsagar AV, Coresh J, Brancati F, Colindres RE. "Ankle brachial index independently predicts early kidney disease." Ren Fail. 2004;26(4):433-43.
Tsai AW, Folsom AR, Rosamond WD, Jones DW. "Ankle-brachial index and 7-year ischemic stroke incidence: the ARIC study." Stroke. 2001;32(8):1721-4.
Iso H, Folsom AR, Koike KA, et al. "Antigens of tissue plasminogen activator and plasminogen activator inhibitor 1: correlates in nonsmoking Japanese and Caucasian men and women." Thromb Haemost. 1993;70(3):475-80.
Blair CK, Folsom AR, Knopman DS, Bray MS, Mosley TH, Boerwinkle E. "APOE genotype and cognitive decline in a middle-aged cohort." Neurology. 2005;64(2):268-76.
Maxwell TJ, Ballantyne CM, Cheverud JM, Guild CS, Ndumele CE. "APOE modulates the correlation between triglycerides, cholesterol, and CHD through pleiotropy, and gene-by-gene interactions." Genetics. 2013;195(4):1397-405.
Klos K, Shimmin L, Ballantyne C, et al. "APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels." Hum Mol Genet. 2008;17(13):2039-46.
Hsu CC, Kao LWH, Coresh J, et al. "Apolipoprotein E and progression of chronic kidney disease." JAMA. 2005;293(23):2892-9.
Liew G, Shankar A, Wang J J, et al. "Apolipoprotein E gene polymorphisms and retinal vascular signs: the atherosclerosis risk in communities (ARIC) study." Arch Ophthalmol. 2007;125(6):813-8.
Volcik KA, Barkley R A, Hutchinson RG, et al. "Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants." Am J Epidemiol. 2006;164(4):342-8.
Weitzman S, Wang C-H, Pankow JS, Schmidt MI, Brancati FL. "Are measures of height and leg length related to incident diabetes mellitus? The ARIC (Atherosclerosis Risk in Communities) study." Acta Diabetol. 2010;47(3):237-42.
Klein R, Sharrett AR, Klein BE, et al. "Are retinal arteriolar abnormalities related to atherosclerosis?: The Atherosclerosis Risk in Communities Study." Arterioscler Thromb Vasc Biol. 2000;20(6):1644-50.
"Are There Clinical Implications of Racial Differences in HbA1c? A Difference, to Be a Difference, Must Make a Difference." Diabetes Care. 2016;39(8):1462-7.
Diez-Roux AV, Kiefe CI, Jacobs DR, et al. "Area characteristics and individual-level socioeconomic position indicators in three population-based epidemiologic studies." Ann Epidemiol. 2001;11(6):395-405.
Merkin S S, Coresh J, Diez Roux AV, Taylor HA, Powe NR. "Area socioeconomic status and progressive CKD: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2005;46(2):203-13.
Matijevic N, Wu KK, Nidkarni N, Heiss G, Folsom AR. "The ARIC carotid MRI study of blood cellular markers: an inverse association of monocyte myeloperoxidase content with peripheral arterial disease." Angiology. 2011;62(3):237-44.
Schmitz KH, Arnett DK, Bank A, et al. "Arterial distensibility and physical activity in the ARIC study." Med Sci Sports Exerc. 2001;33(12):2065-71.
Din-Dzietham R, Couper D, Evans G, Arnett DK, Jones DW. "Arterial stiffness is greater in African Americans than in whites: evidence from the Forsyth County, North Carolina, ARIC cohort." Am J Hypertens. 2004;17(4):304-13.
Burke GL, Evans GW, Riley WA, et al. "Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults. The Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 1995;26(3):386-91.
Lindström S, Germain M, Crous-Bou M, et al. "Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study." Hum Genet. 2017;136(7):897-902.
Ellervik C, Roselli C, Christophersen IE, et al. "Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study." JAMA Cardiol. 2019;4(2):144-152.
Speliotes EK, Willer CJ, Berndt SI, et al. "Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index." Nat Genet. 2010;42(11):937-48.
Fuchs FD, Chambless LE, Folsom AR, et al. "Association between alcoholic beverage consumption and incidence of coronary heart disease in whites and blacks: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2004;160(5):466-74.
Yu Z, Rebholz CM, Wong E, Chen Y, Matsushita K, Coresh JJ. "Association Between Hypertension and Kidney Function Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2019;74(3):310-319.
Johnson EL, Krauss GL, Lee AK, et al. "Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study." JAMA Neurol. 2018;75(11):1375-1382.
Gottesman RF, Schneider ALC, Zhou Y, et al. "Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition." JAMA. 2017;317(14):1443-1450.
Oliver-Williams C, Vladutiu CJ, Loehr LR, Rosamond WD. "The Association Between Parity and Subsequent Cardiovascular Disease in Women: The Atherosclerosis Risk in Communities Study." J Womens Health (Larchmt). 2019;28(5):721-727.
Rasmussen-Torvik LJ, Li M, Kao WH, et al. "Association of a fasting glucose genetic risk score with subclinical atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) study." Diabetes. 2011;60(1):331-5.
Rasmussen-Torvik LJ, Cushman M, Tsai MY, et al. "The association of alpha-fibrinogen Thr312Ala polymorphism and venous thromboembolism in the LITE study." Thromb Res. 2007;121(1):1-7.
Huang T, Wang T, Zheng Y, et al. "Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study." JAMA Netw Open. 2019;2(9):e1910915.
Franceschini N, North KE, Arnett D, et al. "The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study." Am J Hypertens. 2009;22(5):552-8.
Dearborn-Tomazos JL, Wu A, Steffen LM, et al. "Association of Dietary Patterns in Midlife and Cognitive Function in Later Life in US Adults Without Dementia." JAMA Netw Open. 2019;2(12):e1916641.
Kubota Y, Heiss G, Maclehose RF, Roetker NS. "Association of Educational Attainment With Lifetime Risk of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Intern Med. 2017;177(8):1165-1172.
Schick UM, Auer PL, Bis JC, et al. "Association of exome sequences with plasma C-reactive protein levels in >9000 participants." Hum Mol Genet. 2015;24(2):559-71.
Zhang L, Spencer KL, V Voruganti S, et al. "Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study." Am J Epidemiol. 2013;177(9):923-32.
Yu B, Barbalic M, Brautbar A, et al. "Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies." Circ Cardiovasc Genet. 2013;6(1):82-8.
Smith NL, Felix JF, Morrison AC, et al. "Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium." Circ Cardiovasc Genet. 2010;3(3):256-66.
Hardy DS, Hoelscher DM, Aragaki C, et al. "Association of glycemic index and glycemic load with risk of incident coronary heart disease among Whites and African Americans with and without type 2 diabetes: the Atherosclerosis Risk in Communities study." Ann Epidemiol. 2010;20(8):610-6.
Kim Y, Matsushita K, Sang Y, et al. "Association of high-sensitivity cardiac troponin T and natriuretic peptide with incident ESRD: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(4):550-8.
Oyenuga AO, Folsom AR, Lutsey PL. "Association of Life's Simple 7 with reduced clinically manifest abdominal aortic aneurysm: The ARIC study." Vasc Med. 2019;24(3):224-229.
Peloso GM, Auer PL, Bis JC, et al. "Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks." Am J Hum Genet. 2014;94(2):223-32.
Ashar FN, Moes A, Moore AZ, et al. "Association of mitochondrial DNA levels with frailty and all-cause mortality." J Mol Med (Berl). 2015;93(2):177-186.
Kingah PL, Luu HN, Volcik KA, Morrison AC, Nettleton JA, Boerwinkle E. "Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study." Hypertens Res. 2010;33(2):165-9.
Dehghan A, Yang Q, Peters A, et al. "Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts." Circ Cardiovasc Genet. 2009;2(2):125-33.
Köttgen A, Hsu CC, Coresh J, et al. "The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults." Am J Kidney Dis. 2008;52(5):868-75.
Sharrett AR, Chambless LE, Heiss G, Paton CC, Patsch W. "Association of postprandial triglyceride and retinyl palmitate responses with asymptomatic carotid artery atherosclerosis in middle-aged men and women. The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb Vasc Biol. 1995;15(12):2122-9.
Yu B, Li AH, Muzny D, et al. "Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease." Circ Cardiovasc Genet. 2015;8(2):351-5.
Tamariz L, Agarwal S, Soliman EZ, et al. "Association of serum uric acid with incident atrial fibrillation (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2011;108(9):1272-6.
Gellert KS, Alonso A, Chen LYee, Meyer ML, Soliman EZ, Suzuki T. "Association of Sleep Apnea, Diagnosed by Self-Reported Physician Diagnosis or Hospital Discharge Codes, With Atrial Fibrillation and Ectopy Using Ambulatory Electrocardiogram in the ARIC Study." Circ Arrhythm Electrophysiol. 2020;13(4):e007574.
Vaidean GD, Rautaharju PM, Prineas RJ, et al. "The association of spatial T wave axis deviation with incident coronary events. The ARIC cohort." BMC Cardiovasc Disord. 2005;5(1):2.
Weatherley BD, Nelson JJ, Heiss G, et al. "The association of the ankle-brachial index with incident coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study, 1987-2001." BMC Cardiovasc Disord. 2007;7:3.
Volcik KA, Ballantyne CM, Braun MC, Coresh J, Mosley TH, Boerwinkle E. "Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study." Am J Hypertens. 2008;21(5):533-8.
Kucharska-Newton AM, Monda KL, Campbell S, et al. "Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2011;216(1):151-6.
Duncan BB, Chambless LE, Schmidt MI, et al. "Association of the waist-to-hip ratio is different with wine than with beer or hard liquor consumption. Atherosclerosis Risk in Communities Study Investigators." Am J Epidemiol. 1995;142(10):1034-8.
Simpson RJ, Cascio WE, Crow RS, Schreiner PJ, Rautaharju PM, Heiss G. "Association of ventricular premature complexes with electrocardiographic-estimated left ventricular mass in a population of African-American and white men and women (The Atherosclerosis Risk in Communities." Am J Cardiol. 2001;87(1):49-53.
Bello NA, Cheng S, Claggett B, et al. "Association of Weight and Body Composition on Cardiac Structure and Function in the ARIC Study (Atherosclerosis Risk in Communities)." Circ Heart Fail. 2016;9(8).
Nettleton JA, Steffen LM, Ballantyne CM, Boerwinkle E, Folsom AR. "Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modified by dietary fat intake in African American and White adults." Atherosclerosis. 2007;194(2):e131-40.
Carty CL, Bůžková P, Fornage M, et al. "Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study." Circ Cardiovasc Genet. 2012;5(2):210-6.