ARIC Publications
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Education and Cardiovascular Health as Effect Modifiers of APOE ε4 on Dementia: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2022;77(6):1199-1207.
" "ECG-AI: electrocardiographic artificial intelligence model for prediction of heart failure." Eur Heart J Digit Health. 2021;2(4):626-634.
"Echocardiographic measures and subsequent decline in kidney function in older adults: the Atherosclerosis Risk in Communities Study." Eur Heart J Cardiovasc Imaging. 2021.
"Effect modification of general and central obesity by sex and age on cardiovascular outcomes: Targeted maximum likelihood estimation in the atherosclerosis risk in communities study." Diabetes Metab Syndr. 2021;15(2):479-485.
"Electrophysiological ventricular substrate of stroke: a prospective cohort study in the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open. 2021;11(9):e048542.
"Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease." Hypertension. 2021;78(5):1555-1566.
"Epidemiology of Heart Failure Stages in Middle-Aged Black People in the Community: Prevalence and Prognosis in the Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2021;10(9):e016524.
"Epigenetically mediated electrocardiographic manifestations of sub-chronic exposures to ambient particulate matter air pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Res. 2021;198:111211.
"Epigenome-wide association study of mitochondrial genome copy number." Hum Mol Genet. 2021.
" "Effect of Magnesium Supplementation on Circulating Biomarkers of Cardiovascular Disease." Nutrients. 2020;12(6).
"Endodontic therapy and incident cardiovascular disease: The Atherosclerosis Risk in Communities (ARIC) study." J Public Health Dent. 2020;80(1):79-91.
"Epigenetic Age Acceleration and Cognitive Function in African American Adults in Midlife: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2020;75(3):473-480.
"Evaluation of mitochondrial DNA copy number estimation techniques." PLoS One. 2020;15(1):e0228166.
"Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death." J Am Heart Assoc. 2019;8(23):e013751.
"Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies." Am J Hum Genet. 2019;104(2):260-274.
"Epigenetic Loci of Blood Pressure." Circ Genom Precis Med. 2019;12(1):e002341.
"Estimating the association between blood pressure variability and cardiovascular disease: An application using the ARIC Study." Stat Med. 2019;38(10):1855-1868.
"Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls." Nature. 2019;570(7759):71-76.
"Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.
"Early versus late percutaneous revascularization in patients hospitalized with non ST-segment elevation myocardial infarction: The atherosclerosis risk in communities surveillance study." Catheter Cardiovasc Interv. 2018;91(2):253-259.
"Enhancing the Infrastructure of the Atherosclerosis Risk in Communities (ARIC) Study for Cancer Epidemiology Research: ARIC Cancer." Cancer Epidemiol Biomarkers Prev. 2018;27(3):295-305.
"An Epigenome-Wide Association Study of Obesity-Related Traits." Am J Epidemiol. 2018;187(8):1662-1669.
"An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression." Clin Epigenetics. 2018;10:3.
"Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol." Clin Chem. 2018;64(5):843-850.
"Evaluation of the relationship between plasma lipids and abdominal aortic aneurysm: A Mendelian randomization study." PLoS One. 2018;13(4):e0195719.
"Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging." Stroke. 2018;49(8):1812-1819.
"Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6." Genome Biol. 2018;19(1):87.
"ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals." Circ Genom Precis Med. 2018;11(1):e001758.
"Ectopy on a Single 12-Lead ECG, Incident Cardiac Myopathy, and Death in the Community." J Am Heart Assoc. 2017;6(8).
"Effects of Age and Functional Status on the Relationship of Systolic Blood Pressure With Mortality in Mid and Late Life: The ARIC Study." J Gerontol A Biol Sci Med Sci. 2017;72(1):89-94.
"Electrical risk score beyond the left ventricular ejection fraction: prediction of sudden cardiac death in the Oregon Sudden Unexpected Death Study and the Atherosclerosis Risk in Communities Study." Eur Heart J. 2017;38(40):3017-3025.
"Electrocardiographic intervals associated with incident atrial fibrillation: Dissecting the QT interval." Heart Rhythm. 2017;14(5):654-660.
"Electrocardiographic QRS-T angle and the risk of incident silent myocardial infarction in the Atherosclerosis Risk in Communities study." J Electrocardiol. 2017;50(5):661-666.
"Epigenome-wide association studies identify DNA methylation associated with kidney function." Nat Commun. 2017;8(1):1286.
"Evaluation of the modified FINDRISC to identify individuals at high risk for diabetes among middle-aged white and black ARIC study participants." Diabetes Obes Metab. 2017;19(9):1260-1266.
"Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index." Mol Psychiatry. 2017;22(2):192-201.
"Exome-wide association study of plasma lipids in >300,000 individuals." Nat Genet. 2017;49(12):1758-1766.
"An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans." Diabetes. 2017;66(11):2888-2902.
"Echocardiographic Predictors of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study and Cardiovascular Health Study." Circ Cardiovasc Imaging. 2016;9(8).
"On Efficient and Accurate Calculation of Significance P-Values for Sequence Kernel Association Testing of Variant Set." Ann Hum Genet. 2016;80(2):123-35.
"Electrocardiographic Advanced Interatrial Block and Atrial Fibrillation Risk in the General Population." Am J Cardiol. 2016;117(11):1755-9.
"Electrocardiographic J Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2016;118(6):811-815.
"An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group." Genet Epidemiol. 2016;40(5):404-15.
"Epigenetic Signatures of Cigarette Smoking." Circ Cardiovasc Genet. 2016;9(5):436-447.
"Estimating the Time-Varying Joint Effects of Obesity and Smoking on All-Cause Mortality Using Marginal Structural Models." Am J Epidemiol. 2016;183(2):122-9.
"An exome array study of the plasma metabolome." Nat Commun. 2016;7:12360.
"Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits." Am J Hum Genet. 2016;99(1):8-21.
"Electrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities study." Ann Neurol. 2015;78(5):670-8.
"Electrocardiographic repolarization-related predictors of coronary heart disease and sudden cardiac deaths in men and women with cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study." J Electrocardiol. 2015;48(1):101-11.
"Eligibility for statin therapy according to new cholesterol guidelines and prevalent use of medication to lower lipid levels in an older US Cohort: the Atherosclerosis Risk in Communities Study Cohort." JAMA Intern Med. 2015;175(1):138-40.
"Endogenous testosterone and its relationship to preclinical and clinical measures of cardiovascular disease in the atherosclerosis risk in communities study." J Clin Endocrinol Metab. 2015;100(4):1602-8.
"Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci." Hum Mol Genet. 2015;24(15):4464-79.
"Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference." Obesity (Silver Spring). 2015;23(7):1493-501.
"Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data." Lancet Diabetes Endocrinol. 2015;3(7):514-25.
"Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy." Cell Rep. 2015;12(7):1169-83.
"Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction." Nature. 2015;518(7537):102-6.
"Echocardiographic measures of cardiac structure and function are associated with risk of atrial fibrillation in blacks: the Atherosclerosis Risk in Communities (ARIC) study." PLoS One. 2014;9(10):e110111.
"Effect of genetic variants associated with plasma homocysteine levels on stroke risk." Stroke. 2014;45(7):1920-4.
"Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations." Am J Hum Genet. 2014;95(1):49-65.
"Electrocardiographic deep terminal negativity of the P wave in V(1) and risk of sudden cardiac death: the Atherosclerosis Risk in Communities (ARIC) study." J Am Heart Assoc. 2014;3(6):e001387.
"Elevated hepatic enzymes and incidence of venous thromboembolism: a prospective study." Ann Epidemiol. 2014;24(11):817-821.e2.
"An empirical comparison of meta-analysis and mega-analysis of individual participant data for identifying gene-environment interactions." Genet Epidemiol. 2014;38(4):369-78.
"An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval." Am J Hum Genet. 2014;94(6):854-69.
" "Effects of rare and common blood pressure gene variants on essential hypertension: results from the Family Blood Pressure Program, CLUE, and Atherosclerosis Risk in Communities studies." Circ Res. 2013;112(2):318-26.
"Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study." BMC Med Genet. 2013;14:6.
"Electrocardiographic predictors of coronary heart disease and sudden cardiac deaths in men and women free from cardiovascular disease in the Atherosclerosis Risk in Communities study." J Am Heart Assoc. 2013;2(3):e000061.
"Electrocardiographic predictors of incident heart failure in men and women free from manifest cardiovascular disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2013;112(6):843-9.
"Elevated high-sensitivity C-reactive protein as a risk marker of the attenuated relationship between serum cholesterol and cardiovascular events at older age. The ARIC Study." Am J Epidemiol. 2013;178(7):1076-84.
"Epidemiology and long-term clinical and biologic risk factors for pneumonia in community-dwelling older Americans: analysis of three cohorts." Chest. 2013;144(3):1008-1017.
"Estimated plasma stearoyl co-A desaturase-1 activity and risk of incident diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Metabolism. 2013;62(1):100-8.
"Estimating parsimonious models of longitudinal causal effects using regressions on propensity scores." Stat Med. 2013;32(22):3829-37.
"Exploring the genetic basis of chronic periodontitis: a genome-wide association study." Hum Mol Genet. 2013;22(11):2312-24.
"Education and cognitive change over 15 years: the atherosclerosis risk in communities study." J Am Geriatr Soc. 2012;60(10):1847-53.
"Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2012;224(2):435-9.
"Effect of correcting for long-term variation in major coronary heart disease risk factors: relative hazard estimation and risk prediction in the Atherosclerosis Risk in Communities Study." Ann Epidemiol. 2012;22(3):191-7.
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