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ARIC Publications

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Journal Article
Iribarren C, Sempos CT, Eckfeldt JH, Folsom AR. "Lack of association between ferritin level and measures of LDL oxidation: the ARIC study. Atherosclerosis Risk in Communities." Atherosclerosis. 1998;139(1):189-95.
Bielinski SJ, Pankow JS, Boerwinkle E, Bray MS, Kao LWH, Folsom AR. "Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study." Acta Diabetol. 2008;45(3):179-82.
Larson N, Hutchinson R, Boerwinkle E. "Lack of association of 3 functional gene variants with hypertension in African Americans." Hypertension. 2000;35(6):1297-300.
Folsom AR, George KM. "Lack of association of plasma factor XI with incident stroke and coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2015;243(1):181-5.
Yamagishi K, Cushman M, Heckbert SR, Tsai MY, Folsom AR. "Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study." Br J Haematol. 2009;145(2):221-6.
Zhang L, Bůžková P, Wassel CL, et al. "Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study." Atherosclerosis. 2013;228(2):390-9.
Juraschek SP, Shantha GPalamaner, Chu AY, et al. "Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study." PLoS One. 2013;8(1):e55113.
Ellis J, Lange EM, Li J, et al. "Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans." Hum Genet. 2014;133(8):985-95.
Sarnowski C, Cousminer DL, Franceschini N, et al. "Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche." Hum Reprod. 2021;36(7):1999-2010.
Christophersen IE, Rienstra M, Roselli C, et al. "Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation." Nat Genet. 2017;49(6):946-952.
Scott RA, Lagou V, Welch RP, et al. "Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways." Nat Genet. 2012;44(9):991-1005.
Morris AP, Voight BF, Teslovich TM, et al. "Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes." Nat Genet. 2012;44(9):981-90.
Lindström S, Brody JA, Turman C, et al. "A large-scale exome array analysis of venous thromboembolism." Genet Epidemiol. 2019;43(4):449-457.
Tajuddin SM, Schick UM, Eicher JD, et al. "Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases." Am J Hum Genet. 2016;99(1):22-39.
Asselbergs FW, Guo Y, van Iperen EPA, et al. "Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci." Am J Hum Genet. 2012;91(5):823-38.
Wild PS, Felix JF, Schillert A, et al. "Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function." J Clin Invest. 2017;127(5):1798-1812.
Tang W, Kowgier M, Loth DW, et al. "Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function." PLoS One. 2014;9(7):e100776.
Day FR, Ruth KS, Thompson DJ, et al. "Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair." Nat Genet. 2015;47(11):1294-1303.
Barbalic M, Dupuis J, Dehghan A, et al. "Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels." Hum Mol Genet. 2010;19(9):1863-72.
Sung YJ, Winkler TW, Fuentes Lde Las, et al. "A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure." Am J Hum Genet. 2018;102(3):375-400.
Tin A, Li Y, Brody JA, et al. "Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels." Nat Commun. 2018;9(1):4228.
M McDoom M, Palta P, Vart P, Juraschek SP, Kucharska-Newton AMaria, Diez Roux AV. "Late life socioeconomic status and hypertension in an aging cohort: the Atherosclerosis Risk in Communities Study." J Hypertens. 2018;36(6):1382-1390.
Johnson EL, Krauss GL, Walker KA, et al. "Late-onset epilepsy and 25-year cognitive change: The Atherosclerosis Risk in Communities (ARIC) study." Epilepsia. 2020;61(8):1764-1773.
Bianco F, De Caterina R, Chandra A, et al. "Left Atrial Remodeling and Stroke in Patients With Sinus Rhythm and Normal Ejection Fraction: ARIC-NCS." J Am Heart Assoc. 2022;11(9):e024292.
Gonçalves A, Hung C-L, Claggett B, et al. "Left Atrial Structure and Function Across the Spectrum of Cardiovascular Risk in the Elderly: The Atherosclerosis Risk in Communities Study." Circ Cardiovasc Imaging. 2016;9(2):e004010.
Minamisawa M, Inciardi RM, Claggett B, et al. "Left atrial structure and function of the amyloidogenic V122I transthyretin variant in elderly African Americans." Eur J Heart Fail. 2021;23(8):1290-1295.
Taylor HA, Penman AD, Han H, et al. "Left ventricular architecture and survival in African-Americans free of coronary heart disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2007;99(10):1413-20.
Blecker S, Matsushita K, Fox E, et al. "Left ventricular dysfunction as a risk factor for cardiovascular and noncardiovascular hospitalizations in African Americans." Am Heart J. 2010;160(3):488-95.
Okwuosa TM, Soliman EZ, Norby FL, Williams KA, Alonso A. "Left ventricular hypertrophy and cardiovascular disease risk prediction and reclassification in blacks and whites: the Atherosclerosis Risk in Communities Study." Am Heart J. 2015;169(1):155-61.e5.
Fox ER, Taylor HA, Benjamin EJ, et al. "Left ventricular mass indexed to height and prevalent MRI cerebrovascular disease in an African American cohort: the Atherosclerotic Risk in Communities study." Stroke. 2005;36(3):546-50.
Nkomo VT, Arnett DK, Benjamin EJ, Liebson PR, Hutchinson RG, Skelton TN. "Left ventricular structure and systolic function in African Americans: the Atherosclerosis Risk in Communities (ARIC) study." Ethn Dis. 2004;14(4):483-8.
Palta P, Sharrett ARichey, Deal JA, et al. "Leisure-time physical activity sustained since midlife and preservation of cognitive function: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2019;15(2):273-281.
Kats D, Evenson KR, Zeng D, Avery CL, Palta P, Kritchevsky SB. "Leisure-time physical activity volume, intensity, and duration from mid- to late-life in U.S. subpopulations by race and sex. The Atherosclerosis Risk In Communities (ARIC) Study." Aging (Albany NY). 2020;12(5):4592-4602.
Schmidt MI, Duncan BB, Vigo A, et al. "Leptin and incident type 2 diabetes: risk or protection?" Diabetologia. 2006;49(9):2086-96.
Eldomery MK, Coban-Akdemir Z, Harel T, et al. "Lessons learned from additional research analyses of unsolved clinical exome cases." Genome Med. 2017;9(1):26.
Nieto FJ, Szklo M, Folsom AR, Rock R, Mercuri M. "Leukocyte count correlates in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1992;136(5):525-37.
Gondalia R, Holliday KM, Baldassari A, et al. "Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
Aguilar D, Sun C, Hoogeveen RC, et al. "Levels and Change in Galectin-3 and Association With Cardiovascular Events: The ARIC Study." J Am Heart Assoc. 2020;9(13):e015405.
Andriankaja OM, Barros SP, Moss K, et al. "Levels of serum interleukin (IL)-6 and gingival crevicular fluid of IL-1beta and prostaglandin E(2) among non-smoking subjects with gingivitis and type 2 diabetes." J Periodontol. 2009;80(2):307-16.
Claussnitzer M, Dankel SN, Klocke B, et al. "Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms." Cell. 2014;156(1-2):343-58.
He KY, Li X, Kelly TN, et al. "Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data." Hum Genet. 2019;138(2):199-210.
Chichlowska KL, Rose KM, Diez-Roux AV, Golden SH, McNeill AM, Heiss G. "Life course socioeconomic conditions and metabolic syndrome in adults: the Atherosclerosis Risk in Communities (ARIC) Study." Ann Epidemiol. 2009;19(12):875-83.
Power MC, Schneider ALC, Wruck L, et al. "Life-course blood pressure in relation to brain volumes." Alzheimers Dement. 2016;12(8):890-9.
George KM, Lutsey PL, Kucharska-Newton AMaria, Palta P, Heiss G, Osypuk T. "Life-Course Individual and Neighborhood Socioeconomic Status and Risk of Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." Am J Epidemiol. 2020;189(10):1134-1142.
Xiao Q, Heiss G, Kucharska-Newton A, Bey G, Love S-AM, Whitsel EA. "Life-Course Neighborhood Socioeconomic Status and Cardiovascular Events in Black and White Adults in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2022;191(8):1470-1484.
Garg PK, O'Neal WT, Mok Y, Heiss G, Coresh JJ. "Life's Simple 7 and Peripheral Artery Disease Risk: The Atherosclerosis Risk in Communities Study." Am J Prev Med. 2018;55(5):642-649.
Commodore-Mensah Y, Mok Y, Gottesman RF, et al. "Life's Simple 7 at Midlife and Risk of Recurrent Cardiovascular Disease and Mortality after Stroke: The ARIC study." J Stroke Cerebrovasc Dis. 2022;31(7):106486.
Krishnappa D, Wang W, Rooney MR, et al. "Life's Simple 7 cardiovascular health score and premature atrial contractions: The atherosclerosis risk in communities (ARIC) study." Int J Cardiol. 2021.
Evans CR, Hong C-P, Folsom AR, et al. "Lifestyle Moderates Genetic Risk of Venous Thromboembolism: The ARIC Study." Arterioscler Thromb Vasc Biol. 2020;40(11):2756-2763.
Xu H, Schwander K, Brown MR, et al. "Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions." Eur J Hum Genet. 2021;29(5):839-850.
Carson A P, Carson A PL, Rose KM, et al. "Lifetime prevalence of migraine and other headaches lasting 4 or more hours: the Atherosclerosis Risk in Communities (ARIC) study." Headache. 2004;44(1):20-8.
Tang W, Yao L, Roetker NS, et al. "Lifetime Risk and Risk Factors for Abdominal Aortic Aneurysm in a 24-Year Prospective Study: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2016;36(12):2468-2477.
Mou L, Norby FL, Chen LYee, et al. "Lifetime Risk of Atrial Fibrillation by Race and Socioeconomic Status: ARIC Study (Atherosclerosis Risk in Communities)." Circ Arrhythm Electrophysiol. 2018;11(7):e006350.
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
Bell EJ, Lutsey PL, Basu S, Cushman M, Heckbert SR, Lloyd-Jones DM. "Lifetime Risk of Venous Thromboembolism in Two Cohort Studies." Am J Med. 2016;129(3):339.e19-26.
Barral S, Cheng R, Reitz C, et al. "Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease." Alzheimers Dement. 2015;11(12):1397-1406.
Simino J, Kume R, Kraja AT, et al. "Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program." Atherosclerosis. 2014;235(1):84-93.
Marrone MT, Mondul AM, Prizment AE, et al. "Lipid-Lowering Drug Use and Cancer Incidence and Mortality in the ARIC Study." JNCI Cancer Spectr. 2021;5(5).
Kitzmiller JP, Foraker RE, Rose KM. "Lipid-lowering pharmacotherapy and socioeconomic status: Atherosclerosis Risk In Communities (ARIC) surveillance study." BMC Public Health. 2013;13:488.
Rodriguez S, Gaunt TR, Guo Y, et al. "Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array." Eur J Hum Genet. 2016;24(1):106-12.
Pokharel Y, Sun W, Polfus LM, et al. "Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study." Atherosclerosis. 2015;241(2):641-8.
Ma Y, Tucker KL, Smith CE, et al. "Lipoprotein lipase variants interact with polyunsaturated fatty acids for obesity traits in women: replication in two populations." Nutr Metab Cardiovasc Dis. 2014;24(12):1323-9.
Kubota Y, Folsom AR, Ballantyne CM. "Lipoprotein(a) and abdominal aortic aneurysm risk: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2018;268:63-67.
Mehta A, Virani SS, Ayers CR, et al. "Lipoprotein(a) and Family History Predict Cardiovascular Disease Risk." J Am Coll Cardiol. 2020;76(7):781-793.
Ohira T, Schreiner PJ, Morrisett JD, Chambless LE, Rosamond WD, Folsom AR. "Lipoprotein(a) and incident ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2006;37(6):1407-12.
Iso H, Koike KA, Folsom AR, et al. "Lipoprotein(a) and its correlates in Japanese and U.S. population samples." Ann Epidemiol. 1996;6(4):324-30.
Obisesan OH, Kou M, Wang FM, et al. "Lipoprotein(a) and Subclinical Vascular and Valvular Calcification on Cardiac Computed Tomography: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(11):e024870.
Schreiner PJ, Chambless LE, Brown SA, Watson RL, Toole J, Heiss G. "Lipoprotein(a) as a correlate of stroke and transient ischemic attack prevalence in a biracial cohort: the ARIC Study. Atherosclerosis Risk in Communities." Ann Epidemiol. 1994;4(5):351-9.
Schreiner PJ, Morrisett JD, Sharrett AR, et al. "Lipoprotein[a] as a risk factor for preclinical atherosclerosis." Arterioscler Thromb. 1993;13(6):826-33.
Schreiner PJ. "Lipoprotein(a) as a risk factor for preclinical atherosclerotic disease in a biracial cohort: the Atherosclerosis Risk in Communities (ARIC) Study." Chem Phys Lipids. 1994;67-68:405-10.
Saeed A, Sun W, Agarwala A, et al. "Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
Garg PK, Norby FL, Polfus LM, et al. "Lipoprotein-associated phospholipase A and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC)." Atherosclerosis. 2018;268:12-18.
Nambi V, Hoogeveen RC, Chambless L, et al. "Lipoprotein-associated phospholipase A2 and high-sensitivity C-reactive protein improve the stratification of ischemic stroke risk in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2009;40(2):376-81.
Folsom AR, Lutsey PL, Roetker NS, Ballantyne CM, Hoogeveen RC, Rosamond WD. "Lipoprotein-associated phospholipase A2 and venous thromboembolism: a prospective study." Thromb Res. 2013;132(1):44-6.
Ballantyne CM, Hoogeveen RC, Bang H, et al. "Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study." Arch Intern Med. 2005;165(21):2479-84.
Ballantyne CM, Hoogeveen RC, Bang H, et al. "Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2004;109(7):837-42.
Ruban A, Daya N, Schneider ALC, et al. "Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study." J Stroke. 2020;22(3):357-368.
Schneider ALC, Lazo M, Ndumele CE, et al. "Liver enzymes, race, gender and diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study." Diabet Med. 2013;30(8):926-33.
"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Ganesh SK, Tragante V, Guo W, et al. "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.

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