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ARIC Publications

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Caughey MC, Vaduganathan M, Arora S, et al. "Racial Differences and Temporal Obesity Trends in Heart Failure with Preserved Ejection Fraction." J Am Geriatr Soc. 2021.
Hicks CW, Ding N, Kwak L, et al. "Risk of peripheral artery disease according to race and sex: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2021;324:52-57.
Rooney MR, Rawlings AM, Pankow JS, et al. "Risk of Progression to Diabetes Among Older Adults With Prediabetes." JAMA Intern Med. 2021;181(4):511-519.
Hicks CW, Daya NR, Black JH, Matsushita K. "Race and sex-based disparities associated with carotid endarterectomy in the Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2020;292:10-16.
Chen TK, Coresh JJ, Daya N, Ballew SH, Tin A, Crews DC. "Race, APOL1 Risk Variants, and Clinical Outcomes among Older Adults: The ARIC Study." J Am Geriatr Soc. 2020.
Lewis AA, Ayers CR, Selvin E, et al. "Racial Differences in Malignant Left Ventricular Hypertrophy and Incidence of Heart Failure: A Multicohort Study." Circulation. 2020;141(12):957-967.
Chunawala Z, Chang PP, DeFilippis AP, Hall ME, Matsushita K, Caughey MC. "Recurrent Admissions for Acute Decompensated Heart Failure Among Patients With and Without Peripheral Artery Disease: The ARIC Study." J Am Heart Assoc. 2020;9(21):e017174.
Gellert KS, Keil AP, Zeng D, et al. "Reducing the Population Burden of Coronary Heart Disease by Modifying Adiposity: Estimates From the ARIC Study." J Am Heart Assoc. 2020;9(4):e012214.
Deal JA, Power MC, Palta P, et al. "Relationship of Cigarette Smoking and Time of Quitting with Incident Dementia and Cognitive Decline." J Am Geriatr Soc. 2020;68(2):337-345.
Tang W, Saratzis A, Pattee J, et al. "Replication of Newly Identified Genetic Associations Between Abdominal Aortic Aneurysm and SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG." Eur J Vasc Endovasc Surg. 2020;59(1):92-97.
Folsom AR, Lutsey PL, Pope ZC, Fashanu OE, Misialek JR, Cushman M. "Resting heart rate and incidence of venous thromboembolism." Res Pract Thromb Haemost. 2020;4(2):238-246.
Yang C, Kwak L, Ballew SH, et al. "Retinal microvascular findings and risk of incident peripheral artery disease: An analysis from the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2020;294:62-71.
Surapaneni AL, Ballew SH, Coresh JJ, Ballantyne CM, Selvin E, Matsushita K. " Risk Alleles, Cardiac Markers, and Risk of ESKD in African Americans: The Atherosclerosis Risk in Communities Study." Kidney Med. 2020;2(4):502-504.
DeBoer MD, Filipp SL, Sims M, Musani SK. "Risk of Ischemic Stroke Increases Over the Spectrum of Metabolic Syndrome Severity." Stroke. 2020;51(8):2548-2552.
Lee AK, Woodward M, Wang D, et al. "The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE." J Clin Endocrinol Metab. 2020;105(1).
Wang Z, Chen H, Bartz TM, et al. "Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels." Circ Genom Precis Med. 2020;13(4):e002772.
Zhao D, Post WS, Blasco-Colmenares E, et al. "Racial Differences in Sudden Cardiac Death." Circulation. 2019;139(14):1688-1697.
Loomis SJ, Köttgen A, Li M, et al. "Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study." Sci Rep. 2019;9(1):5941.
Folsom AR, Basu S, Hong C-P, Heckbert SR, Lutsey PL, Rosamond WD. "Reasons for Differences in the Incidence of Venous Thromboembolism in Black Versus White Americans." Am J Med. 2019;132(8):970-976.
Maheshwari A, Norby FL, Roetker NS, et al. "Refining Prediction of Atrial Fibrillation-Related Stroke Using the P-CHADS-VASc Score." Circulation. 2019;139(2):180-191.
Wang S, Fashanu OE, Zhao D, et al. "Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20 Years (from the Atherosclerosis Risk in Communities [ARIC] Study)." Am J Cardiol. 2019;123(2):334-340.
Madan N, Lee AK, Matsushita K, Hoogeveen RC, Ballantyne CM, Selvin E. "Relation of Isolated Systolic Hypertension and Pulse Pressure to High-Sensitivity Cardiac Troponin-T and N-Terminal pro-B-Type Natriuretic Peptide in Older Adults (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2019;124(2):245-252.
Koene RJ, M Alraies C, Norby FL, et al. "Relation of the CHADS-VASc Score to Risk of Thrombotic and Embolic Stroke in Community-Dwelling Individuals Without Atrial Fibrillation (From The Atherosclerosis Risk in Communities [ARIC] Study)." Am J Cardiol. 2019;123(3):402-408.
Mamo SK, Reed NS, Sharrett ARichey, et al. "Relationship Between Domain-Specific Cognitive Function and Speech-in-Noise Performance in Older Adults: The Atherosclerosis Risk in Communities Hearing Pilot Study." Am J Audiol. 2019;28(4):1006-1014.
Inker LA, Grams ME, Levey AS, et al. "Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium." Am J Kidney Dis. 2019;73(2):206-217.
Tin A, Yu B, Ma J, et al. "Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay." J Appl Lab Med. 2019;4(1):30-39.
Deal JA, Sharrett ARichey, Albert M, et al. "Retinal signs and risk of incident dementia in the Atherosclerosis Risk in Communities study." Alzheimers Dement. 2019;15(3):477-486.
Rosenthal EA, Shirts BH, Amendola LM, et al. "Rare loss of function variants in candidate genes and risk of colorectal cancer." Hum Genet. 2018;137(10):795-806.
Caughey MC, Sueta CA, Stearns SC, Shah AM, Rosamond WD. "Recurrent Acute Decompensated Heart Failure Admissions for Patients With Reduced Versus Preserved Ejection Fraction (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2018;122(1):108-114.
Mahajan A, Wessel J, Willems SM, et al. "Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes." Nat Genet. 2018;50(4):559-571.
Ni A. "A regularized variable selection procedure in additive hazards model with stratified case-cohort design." Lifetime Data Anal. 2018;24(3):443-463.
Fretz A, McEvoy JW, Rebholz CM, et al. "Relation of Lifestyle Factors and Life's Simple 7 Score to Temporal Reduction in Troponin Levels Measured by a High-Sensitivity Assay (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2018;121(4):430-436.
Wang W, Alonso A, Soliman EZ, et al. "Relation of Resting Heart Rate to Incident Atrial Fibrillation (From ARIC [Atherosclerosis Risk in Communities] Study)." Am J Cardiol. 2018;121(10):1169-1176.
Aeschbacher S, O'Neal WT, Krisai P, et al. "Relationship between QRS duration and incident atrial fibrillation." Int J Cardiol. 2018;266:84-88.
Saeed A, Feofanova EV, Yu B, et al. "Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease." J Am Coll Cardiol. 2018;72(2):156-169.
Pirastu N, Joshi PK, de Vries PS, et al. "Reply to 'Misestimation of heritability and prediction accuracy of male-pattern baldness'." Nat Commun. 2018;9(1):2538.
Folsom AR, Lutsey PL, Klein R, Klein BE. "Retinal microvascular signs and incidence of abdominal aortic aneurysm: The Atherosclerosis Risk in Communities Study." Ophthalmic Epidemiol. 2018;25(3):246-249.
Deal JA, Sharrett ARichey, Rawlings AM, et al. "Retinal signs and 20-year cognitive decline in the Atherosclerosis Risk in Communities Study." Neurology. 2018;90(13):e1158-e1166.
Nochioka K, Roca GQuerejeta, Claggett B, et al. "Right Ventricular Function, Right Ventricular-Pulmonary Artery Coupling, and Heart Failure Risk in 4 US Communities: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2018;3(10):939-948.
Chen Y, Sang Y, Ballew SH, et al. "Race, Serum Potassium, and Associations With ESRD and Mortality." Am J Kidney Dis. 2017;70(2):244-251.
Fernandes-Silva MM, Shah AM, Hegde S, et al. "Race-Related Differences in Left Ventricular Structural and Functional Remodeling in Response to Increased Afterload: The ARIC Study." JACC Heart Fail. 2017;5(3):157-165.
Naorungroj S, Slade GD, Divaris K, Heiss G, Offenbacher S. "Racial differences in periodontal disease and 10-year self-reported tooth loss among late middle-aged and older adults: the dental ARIC study." J Public Health Dent. 2017;77(4):372-382.
Qiao Y, Suri FK, Zhang Y, et al. "Racial Differences in Prevalence and Risk for Intracranial Atherosclerosis in a US Community-Based Population." JAMA Cardiol. 2017;2(12):1341-1348.
Nadruz W, Claggett B, Henglin M, et al. "Racial Disparities in Risks of Stroke." N Engl J Med. 2017;376(21):2089-2090.
Deal JA, Albert MS, Arnold M, et al. "A randomized feasibility pilot trial of hearing treatment for reducing cognitive decline: Results from the Aging and Cognitive Health Evaluation in Elders Pilot Study." Alzheimers Dement (N Y). 2017;3(3):410-415.
Marouli E, Graff M, Medina-Gomez C, et al. "Rare and low-frequency coding variants alter human adult height." Nature. 2017;542(7640):186-190.
Nandakumar P, Lee D, Richard MA, et al. "Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry." J Hypertens. 2017;35(7):1381-1389.
Sims R, van der Lee SJ, Naj AC, et al. "Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease." Nat Genet. 2017;49(9):1373-1384.
Maheshwari A, Norby FL, Soliman EZ, et al. "Relation of Prolonged P-Wave Duration to Risk of Sudden Cardiac Death in the General Population (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(9):1302-1306.
Zewinger S, Kleber ME, Tragante V, et al. "Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study." Lancet Diabetes Endocrinol. 2017;5(7):534-543.
B Windham G, Harrison KL, Lirette ST, et al. "Relationship Between Midlife Cardiovascular Health and Late-Life Physical Performance: The ARIC Study." J Am Geriatr Soc. 2017;65(5):1012-1018.
Meyer ML, Soliman EZ, Wruck LM, et al. "Repeatability of ectopic beats from 48-hr ambulatory electrocardiography: The Atherosclerosis Risk in Communities (ARIC) Study." Ann Noninvasive Electrocardiol. 2017;22(4).
Jansen H, Willenborg C, Lieb W, et al. "Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation." J Rheumatol. 2017;44(1):4-10.
Lee AK, Lee CJ, Huang ES, Sharrett ARichey, Coresh JJ. "Risk Factors for Severe Hypoglycemia in Black and White Adults With Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2017;40(12):1661-1667.
Zhang Z-M, Rautaharju PM, Prineas RJ, et al. "Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(22):2141-8.
Parrinello CM, Sharrett ARichey, Maruthur NM, Bergenstal RM, Grams ME, Coresh JJ. "Racial Differences in and Prognostic Value of Biomarkers of Hyperglycemia." Diabetes Care. 2016;39(4):589-95.
Magnani JW, Norby FL, Agarwal SK, Soliman EZ, Chen LYee, Loehr LR. "Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2016;1(4):433-41.
Lacy ME, Wellenius GA, Carnethon MR, et al. "Racial Differences in the Performance of Existing Risk Prediction Models for Incident Type 2 Diabetes: The CARDIA Study." Diabetes Care. 2016;39(2):285-91.
Kapoor A, Bakshy K, Xu L, et al. "Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
Yu B, Pulit SL, Hwang S-J, et al. "Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk." Circ Cardiovasc Genet. 2016;9(1):64-70.
Olfson E, Saccone NL, Johnson EO, et al. "Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans." Mol Psychiatry. 2016;21(5):601-7.
Kan M, Auer PL, Wang GT, et al. "Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
Zanoni P, Khetarpal SA, Larach DB, et al. "Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease." Science. 2016;351(6278):1166-71.
Lalani SR, Liu P, Rosenfeld JA, et al. "Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations." Am J Hum Genet. 2016;98(2):347-57.
Waikar SS, Sabbisetti V, rnlöv JÄ, et al. "Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies." Nephrol Dial Transplant. 2016;31(9):1460-70.
Rebholz CM, Anderson CAM, Grams ME, et al. "Relationship of the American Heart Association's Impact Goals (Life's Simple 7) With Risk of Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Cohort Study." J Am Heart Assoc. 2016;5(4):e003192.
Meyer ML, Tanaka H, Palta P, et al. "Repeatability of Central and Peripheral Pulse Wave Velocity Measures: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(4):470-5.
Folsom AR, Tang W, Weng L-C, Roetker NS, Cushman M, Basu S. "Replication of a genetic risk score for venous thromboembolism in whites but not in African Americans." J Thromb Haemost. 2016;14(1):83-8.
Seidelmann SB, Claggett B, Bravo PE, et al. "Retinal Vessel Calibers in Predicting Long-Term Cardiovascular Outcomes: The Atherosclerosis Risk in Communities Study." Circulation. 2016;134(18):1328-1338.
Lubin JH, Couper DJ, Lutsey PL, Woodward M, Yatsuya H. "Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
Parrinello CM, Matsushita K, Woodward M, Wagenknecht LE, Coresh JJ. "Risk prediction of major complications in individuals with diabetes: the Atherosclerosis Risk in Communities Study." Diabetes Obes Metab. 2016;18(9):899-906.
Wei P, Cao Y, Zhang Y, Xu Z, Kwak I-Y, Boerwinkle E. "On Robust Association Testing for Quantitative Traits and Rare Variants." G3 (Bethesda). 2016;6(12):3941-3950.
Lutsey PL, Michos ED, Misialek JR, et al. "Race and Vitamin D Binding Protein Gene Polymorphisms Modify the Association of 25-Hydroxyvitamin D and Incident Heart Failure: The ARIC (Atherosclerosis Risk in Communities) Study." JACC Heart Fail. 2015;3(5):347-356.
Reis JP, Michos ED, Selvin E, Pankow JS. "Race, vitamin D-binding protein gene polymorphisms, 25-hydroxyvitamin D, and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2015;101(6):1232-40.
Gupta DK, Claggett B, Wells Q, et al. "Racial differences in circulating natriuretic peptide levels: the atherosclerosis risk in communities study." J Am Heart Assoc. 2015;4(5).
Auer PL, Nalls M, Meschia JF, et al. "Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project." JAMA Neurol. 2015;72(7):781-8.
Huffman JE, de Vries PS, Morrison AC, et al. "Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF." Blood. 2015;126(11):e19-29.
Lunetta KL, Day FR, Sulem P, et al. "Rare coding variants and X-linked loci associated with age at menarche." Nat Commun. 2015;6:7756.
Yazdani A, Yazdani A. "Rare variants analysis using penalization methods for whole genome sequence data." BMC Bioinformatics. 2015;16:405.
Parrinello CM, Grams ME, Couper DJ, et al. "Recalibration of blood analytes over 25 years in the atherosclerosis risk in communities study: impact of recalibration on chronic kidney disease prevalence and incidence." Clin Chem. 2015;61(7):938-47.