ARIC Publications
Heart Failure Risk Associated With Severity of Modifiable Heart Failure Risk Factors: The ARIC Study." J Am Heart Assoc. 2022;11(4):e021583.
"Identification of novel susceptibility methylation loci for pancreatic cancer in a two-phase epigenome-wide association study." Epigenetics. 2022:1-16.
"Impact of Socioeconomic Status on Mortality and Readmission in Patients With Heart Failure With Reduced Ejection Fraction: The ARIC Study." J Am Heart Assoc. 2022;11(18):e024057.
"Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV." Sci Rep. 2022;12(1):577.
"Individual Life-Course Socioeconomic Position and Hearing Aid Use in the Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2022;77(3):645-653.
"Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension." Hypertension. 2022;79(8):1656-1667.
"Integrative analysis of clinical and epigenetic biomarkers of mortality." Aging Cell. 2022;21(6):e13608.
"Kidney Function and Lipid Levels in Older Adults: The Atherosclerosis Risk in Communities Study." Kidney Med. 2022;4(7):100494.
" Kidney Risk Variants and Proteomics." Clin J Am Soc Nephrol. 2022;17(5):684-692.
"A large-scale transcriptome-wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine-mapping." Genet Epidemiol. 2022;46(1):3-16.
"Left Atrial Remodeling and Stroke in Patients With Sinus Rhythm and Normal Ejection Fraction: ARIC-NCS." J Am Heart Assoc. 2022;11(9):e024292.
"Life-Course Neighborhood Socioeconomic Status and Cardiovascular Events in Black and White Adults in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2022;191(8):1470-1484.
"Life's Simple 7 at Midlife and Risk of Recurrent Cardiovascular Disease and Mortality after Stroke: The ARIC study." J Stroke Cerebrovasc Dis. 2022;31(7):106486.
"Life's Simple 7 Cardiovascular Health Score in Relation to Arrhythmias on Extended Ambulatory Electrocardiographic Monitoring (from the Multi-Ethnic Study of Atherosclerosis)." Am J Cardiol. 2022;170:63-70.
"Lipoprotein(a) and Subclinical Vascular and Valvular Calcification on Cardiac Computed Tomography: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(11):e024870.
"Long-term changes in plasma proteomic profiles in premenopausal and postmenopausal Black and White women: the Atherosclerosis Risk in Communities study." Menopause. 2022;29(10):1150-1160.
"Machine Learning-Based Models Incorporating Social Determinants of Health vs Traditional Models for Predicting In-Hospital Mortality in Patients With Heart Failure." JAMA Cardiol. 2022;7(8):844-854.
"Mediation effects of diabetes and inflammation on the relationship of obesity to cognitive impairment in African Americans." J Am Geriatr Soc. 2022.
"Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential." Sci Adv. 2022;8(14):eabl6579.
"Menopausal hormone therapy and risk of cardiovascular events in women with prediabetes or type 2 diabetes: A pooled analysis of 2917 postmenopausal women." Atherosclerosis. 2022;344:13-19.
"Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels." Commun Biol. 2022;5(1):336.
"Metabolite profiling of CKD progression in the chronic renal insufficiency cohort (CRIC) study." JCI Insight. 2022.
"Methods for stroke severity assessment by chart review in the Atherosclerosis Risk in Communities study." Sci Rep. 2022;12(1):12338.
"Midlife Cardiovascular Health and Robust Versus Frail Late-Life Status: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2022;77(6):1222-1229.
"Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2022;350:82-89.
"Migraine and atrial fibrillation: a systematic review." Eur J Neurol. 2022;29(3):910-920.
"Monogenic and Polygenic Contributions to QTc Prolongation in the Population." Circulation. 2022;145(20):1524-1533.
"Is an MRI-derived anatomical measure of dementia risk also a measure of brain aging?" Geroscience. 2022.
"Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation." Nat Genet. 2022;54(5):560-572.
"Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study." Diabetologia. 2022;65(3):477-489.
"The Neuroanatomic Correlates of Olfactory Identification Impairment in Healthy Older Adults and in Persons with Mild Cognitive Impairment." J Alzheimers Dis. 2022;89(1):233-245.
"New insights into the genetic etiology of Alzheimer's disease and related dementias." Nat Genet. 2022;54(4):412-436.
"NT-pro B-type natriuretic peptide, early menopause, and incident heart failure in postmenopausal women of the ARIC study." Menopause. 2022;29(3):309-316.
"Obesity, Galectin-3, and Incident Heart Failure: The ARIC Study." J Am Heart Assoc. 2022;11(9):e023238.
"P Wave Parameters and Indices: A Critical Appraisal of Clinical Utility, Challenges, and Future Research-A Consensus Document Endorsed by the International Society of Electrocardiology and the International Society for Holter and Noninvasive Electrocardio." Circ Arrhythm Electrophysiol. 2022;15(4):e010435.
"Periodontal and other oral bacteria and risk of lung cancer in the Atherosclerosis Risk in Communities (ARIC) Study." Cancer Epidemiol Biomarkers Prev. 2022.
"Periodontal disease measures and risk of incident peripheral artery disease: The Atherosclerosis Risk in Communities (ARIC) Study." J Periodontol. 2022;93(7):943-953.
"Periodontal Status, C-Reactive Protein, NT-proBNP, and Incident Heart Failure: The ARIC Study." JACC Heart Fail. 2022;10(10):731-741.
"Physical Frailty and Brain White Matter Abnormalities: The ARIC Study." J Gerontol A Biol Sci Med Sci. 2022.
"Physical Function and Subsequent Risk of Cardiovascular Events in Older Adults: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(17):e025780.
"Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition." Alzheimers Dement. 2022.
"Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies." Nat Genet. 2022;54(5):593-602.
"Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke." J Am Heart Assoc. 2022;11(15):e025703.
"Polygenic transcriptome risk scores for COPD and lung function improve cross-ethnic portability of prediction in the NHLBI TOPMed program." Am J Hum Genet. 2022;109(5):857-870.
"Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits." Am J Hum Genet. 2022;109(4):669-679.
"Prediction of Incident Heart Failure in CKD: The CRIC Study." Kidney Int Rep. 2022;7(4):708-719.
"Prevalence and outcomes of dehydration in adults with sickle cell trait: the Atherosclerosis Risk in Communities (ARIC) study." Br J Haematol. 2022;198(2):397-400.
"Prevalence and Prognostic Significance of Polyvascular Disease in Patients Hospitalized With Acute Decompensated Heart Failure: The ARIC Study." J Card Fail. 2022;28(8):1267-1277.
"Prognostic significance of obstructive coronary artery disease in patients admitted with acute decompensated heart failure: the ARIC study community surveillance." Eur J Heart Fail. 2022.
"The prospective association between periodontal disease and brain imaging outcomes: The Atherosclerosis Risk in Communities study." J Clin Periodontol. 2022;49(4):322-334.
"Proteomic analysis of diabetes genetic risk scores identifies complement C2 and neuropilin-2 as predictors of type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Diabetologia. 2022.
"Proteomic profiling identifies novel proteins for genetic risk of severe COVID-19: the Atherosclerosis Risk in Communities Study." Hum Mol Genet. 2022;31(14):2452-2461.
"Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis." Am J Respir Crit Care Med. 2022;206(3):321-336.
"Quantifying Individual-Level Inaccuracy in Glomerular Filtration Rate Estimation : A Cross-Sectional Study." Ann Intern Med. 2022;175(8):1073-1082.
"Race- and Gender-Based Differences in Cardiac Structure and Function and Risk of Heart Failure." J Am Coll Cardiol. 2022;79(4):355-368.
"Racial and Ethnic Differences in the Association Between Classical Cardiovascular Risk Factors and Common Carotid Intima-Media Thickness: An Individual Participant Data Meta-Analysis." J Am Heart Assoc. 2022;11(15):e023704.
"Racial Differences in Trends and Prognosis of Guideline-Directed Medical Therapy for Heart Failure with Reduced Ejection Fraction: the Atherosclerosis Risk in Communities (ARIC) Surveillance Study." J Racial Ethn Health Disparities. 2022.
"Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes." Am J Hum Genet. 2022;109(1):81-96.
"Rare coding variants in RCN3 are associated with blood pressure." BMC Genomics. 2022;23(1):148.
"Relation of Diabetes Mellitus to Incident Dementia in Patients With Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2022;165:51-57.
"Relation of Electrocardiographic Abnormal P-Wave Axis With Stroke Mortality in the General Population." Am J Cardiol. 2022;180:59-64.
"Relationship Between Age at Menopause, Obesity, and Incident Heart Failure: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(8):e024461.
"The Relationship Between Atrial Fibrillation, Mitral Regurgitation, and Heart Failure Subtype: The ARIC Study." J Card Fail. 2022;28(6):883-892.
"Relationships of Cerebral Perfusion with Gait Speed across Systolic Blood Pressure Levels and Age: a Cohort Study." J Gerontol A Biol Sci Med Sci. 2022.
"Renin: Measurements, Correlates, and Associations with Long-Term Adverse Kidney Outcomes." Am J Hypertens. 2022.
"Resting heart rate and incident atrial fibrillation: A stratified Mendelian randomization in the AFGen consortium." PLoS One. 2022;17(5):e0268768.
"Risk Factors for Dementia in Patients With Atrial Fibrillation." Am J Cardiol. 2022;174:48-52.
"Risk of Dementia Associated With Atrial Cardiopathy: The ARIC Study." J Am Heart Assoc. 2022;11(16):e025646.
"A semiparametric Gumbel regression model for analyzing longitudinal data with non-normal tails." Stat Med. 2022;41(4):736-750.
"SEMIPARAMETRIC LATENT-CLASS MODELS FOR MULTIVARIATE LONGITUDINAL AND SURVIVAL DATA." Ann Stat. 2022;50(1):487-510.
"Serum Metabolites and Kidney Outcomes: The Atherosclerosis Risk in Communities Study." Kidney Med. 2022;4(9):100522.
"Serum metabolomic signatures of plant-based diets and incident chronic kidney disease." Am J Clin Nutr. 2022;116(1):151-164.
"Serum Metabolomics of Incident Diabetes and Glycemic Changes in a Population With High Diabetes Burden: The Hispanic Community Health Study/Study of Latinos." Diabetes. 2022;71(6):1338-1349.
"Sex and Race Differences in N-Terminal Pro-B-type Natriuretic Peptide Concentration and Absolute Risk of Heart Failure in the Community." JAMA Cardiol. 2022;7(6):623-631.
"Sex-and race-specific burden of aortic valve calcification among older adults without overt coronary heart disease: The Atherosclerosis Risk in Communities Study." Atherosclerosis. 2022;355:68-75.
"STABILITY OF SERUM BONE-MINERAL, KIDNEY, AND CARDIAC BIOMARKERS AFTER A FREEZE-THAW CYCLE: THE ARIC STUDY." Am J Epidemiol. 2022;191(3):534-537.
"Subclinical cardiovascular disease and frailty risk: the atherosclerosis risk in communities study." BMC Geriatr. 2022;22(1):321.
"Targeted Genome Sequencing Identifies Multiple Rare Variants in Caveolin-1 Associated with Obstructive Sleep Apnea." Am J Respir Crit Care Med. 2022.
"Thirty-Year Trends in the Incidence of Atrial Fibrillation: The ARIC Study." J Am Heart Assoc. 2022;11(8):e023583.
"Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts." Diabetes Care. 2022;45(3):674-683.
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