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ARIC Publications

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Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. "Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study." Clin Pharmacol Ther. 2008;83(1):52-60.
Lei HH, Coresh J, Shuldiner AR, Boerwinkle E, Brancati FL. "Variants of the insulin receptor substrate-1 and fatty acid binding protein 2 genes and the risk of type 2 diabetes, obesity, and hyperinsulinemia in African-Americans: the Atherosclerosis Risk in Communities Study." Diabetes. 1999;48(9):1868-72.
Lemaitre RN, Johnson CO, Hesselson S, et al. "Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest." Heart Rhythm. 2014;11(3):471-7.
Li R, Boerwinkle E, Olshan AF, et al. "Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease." Atherosclerosis. 2000;149(2):451-62.
Liang J, Le TH, Edwards DRVelez, et al. "Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations." PLoS Genet. 2017;13(5):e1006728.
Liao D, Cai J, Rosamond WD, et al. "Cardiac autonomic function and incident coronary heart disease: a population-based case-cohort study. The ARIC Study. Atherosclerosis Risk in Communities Study." Am J Epidemiol. 1997;145(8):696-706.
Lieb W, Jansen H, Loley C, et al. "Genetic predisposition to higher blood pressure increases coronary artery disease risk." Hypertension. 2013;61(5):995-1001.
Liese AD, Mayer-Davis EJ, Tyroler HA, et al. "Familial components of the multiple metabolic syndrome: the ARIC study." Diabetologia. 1997;40(8):963-70.
Lindström S, Brody JA, Turman C, et al. "A large-scale exome array analysis of venous thromboembolism." Genet Epidemiol. 2019;43(4):449-457.
Lindström S, Germain M, Crous-Bou M, et al. "Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study." Hum Genet. 2017;136(7):897-902.
Luft VC, Duncan BB, Schmidt MI, et al. "Carboxymethyl lysine, an advanced glycation end product, and incident diabetes: a case-cohort analysis of the ARIC Study." Diabet Med. 2016;33(10):1392-8.
Lutsey PL, Folsom AR, Heckbert SR, Cushman M. "Peak thrombin generation and subsequent venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE) study." J Thromb Haemost. 2009;7(10):1639-48.
Malinow MR, Nieto FJ, Szklo M, Chambless LE, Bond G. "Carotid artery intimal-medial wall thickening and plasma homocyst(e)ine in asymptomatic adults. The Atherosclerosis Risk in Communities Study." Circulation. 1993;87(4):1107-13.
Marrone MT, Selvin E, Barber JR, Platz EA. "Hyperglycemia, Classified with Multiple Biomarkers Simultaneously in Men without Diabetes, and Risk of Fatal Prostate Cancer." Cancer Prev Res (Phila). 2019;12(2):103-112.
McMahon GM, Hwang S-J, Clish CB, et al. "Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease." Kidney Int. 2017;91(6):1426-1435.
McPherson R, Pertsemlidis A, Kavaslar N, et al. "A common allele on chromosome 9 associated with coronary heart disease." Science. 2007;316(5830):1488-91.
Melnick SL, Shahar E, Folsom AR, et al. "Past infection by Chlamydia pneumoniae strain TWAR and asymptomatic carotid atherosclerosis. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Am J Med. 1993;95(5):499-504.
Monda KL, Chen GK, Taylor KC, et al. "A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry." Nat Genet. 2013;45(6):690-6.
Moore M, Folsom AR, Barnes RW, Eckfeldt JH. "No association between serum ferritin and asymptomatic carotid atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1995;141(8):719-23.
Morris AP, Voight BF, Teslovich TM, et al. "Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes." Nat Genet. 2012;44(9):981-90.
Morrison AC, Bray MS, Folsom AR, Boerwinkle E. "ADD1 460W allele associated with cardiovascular disease in hypertensive individuals." Hypertension. 2002;39(6):1053-7.
Morrison AC, Doris PA, Folsom AR, Nieto FJ, Boerwinkle E. "G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke." Stroke. 2001;32(4):822-9.
Patel RS, Schmidt AF, Tragante V, et al. "Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events." Circ Genom Precis Med. 2019;12(4):e002471.
Perry JRB, Voight BF, Yengo L, et al. "Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases." PLoS Genet. 2012;8(5):e1002741.
Rasmussen-Torvik LJ, Cushman M, Tsai MY, et al. "The association of alpha-fibrinogen Thr312Ala polymorphism and venous thromboembolism in the LITE study." Thromb Res. 2007;121(1):1-7.
Rawlings AM, Sharrett ARichey, Golden SH, Windham BG. "Prevalence and correlates of depressive symptoms in older adults across the glycaemic spectrum: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2018;35(5):583-587.
Ray D, Li X, Pan W, Pankow JS. "A Bayesian Partitioning Model for the Detection of Multilocus Effects in Case-Control Studies." Hum Hered. 2015;79(2):69-79.
Raynor LA, Pankow JS, Duncan BB, et al. "Novel risk factors and the prediction of type 2 diabetes in the Atherosclerosis Risk in Communities (ARIC) study." Diabetes Care. 2013;36(1):70-6.
Rebholz CM, Coresh JJ, Ballew SH, McMahon B, Whelton SP, Selvin E. "Kidney Failure and ESRD in the Atherosclerosis Risk in Communities (ARIC) Study: Comparing Ascertainment of Treated and Untreated Kidney Failure in a Cohort Study." Am J Kidney Dis. 2015;66(2):231-9.
Rebholz CM, Astor BC, Grams ME, et al. "Association of plasma levels of soluble receptor for advanced glycation end products and risk of kidney disease: the Atherosclerosis Risk in Communities study." Nephrol Dial Transplant. 2015;30(1):77-83.
Rebholz CM, Grams ME, Lutsey PL, et al. "Biomarkers of Vitamin D Status and Risk of ESRD." Am J Kidney Dis. 2016;67(2):235-42.
Reich D, Nalls MA, Kao LWH, et al. "Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene." PLoS Genet. 2009;5(1):e1000360.
Roselli C, Chaffin MD, Weng L-C, et al. "Multi-ethnic genome-wide association study for atrial fibrillation." Nat Genet. 2018;50(9):1225-1233.
Runchey SS, Folsom AR, Tsai MY, Cushman M, McGovern PD. "Anticardiolipin antibodies as a risk factor for venous thromboembolism in a population-based prospective study." Br J Haematol. 2002;119(4):1005-10.
Sakornsakolpat P, Prokopenko D, Lamontagne M, et al. "Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations." Nat Genet. 2019;51(3):494-505.
Salomaa V, Matei C, Aleksic N, et al. "Soluble thrombomodulin as a predictor of incident coronary heart disease and symptomless carotid artery atherosclerosis in the Atherosclerosis Risk in Communities (ARIC) Study: a case-cohort study." Lancet. 1999;353(9166):1729-34.
Salomaa V, Stinson V, Kark JD, Folsom AR, Davis CE, Wu KK. "Association of fibrinolytic parameters with early atherosclerosis. The ARIC Study. Atherosclerosis Risk in Communities Study." Circulation. 1995;91(2):284-90.
Sanders AE, Divaris K, Naorungroj S, Heiss G. "Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study." J Clin Periodontol. 2015;42(1):12-20.
Schmidt MI, Duncan BB, Vigo A, et al. "Leptin and incident type 2 diabetes: risk or protection?" Diabetologia. 2006;49(9):2086-96.
Selvin E, Coresh J, Golden SH, Brancati FL, Folsom AR, Steffes MW. "Glycemic control and coronary heart disease risk in persons with and without diabetes: the atherosclerosis risk in communities study." Arch Intern Med. 2005;165(16):1910-6.
Shah S, Henry A, Roselli C, et al. "Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure." Nat Commun. 2020;11(1):163.
Shahar E, Heiss G, Rosamond WD, Szklo M. "Baldness and myocardial infarction in men: the atherosclerosis risk in communities study." Am J Epidemiol. 2008;167(6):676-83.
Shimakawa T, Nieto FJ, Malinow MR, Chambless LE, Schreiner PJ, Szklo M. "Vitamin intake: a possible determinant of plasma homocyst(e)ine among middle-aged adults." Ann Epidemiol. 1997;7(4):285-93.
Simone B, De Stefano V, Leoncini E, et al. "Risk of venous thromboembolism associated with single and combined effects of Factor V Leiden, Prothrombin 20210A and Methylenetethraydrofolate reductase C677T: a meta-analysis involving over 11,000 cases and 21,000 controls." Eur J Epidemiol. 2013;28(8):621-47.
Sims R, van der Lee SJ, Naj AC, et al. "Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease." Nat Genet. 2017;49(9):1373-1384.
Sorlie PD, Nieto FJ, Adam E, Folsom AR, Shahar E, Massing M. "A prospective study of cytomegalovirus, herpes simplex virus 1, and coronary heart disease: the atherosclerosis risk in communities (ARIC) study." Arch Intern Med. 2000;160(13):2027-32.
Sorlie PD, Adam E, Melnick SL, et al. "Cytomegalovirus/herpesvirus and carotid atherosclerosis: the ARIC Study." J Med Virol. 1994;42(1):33-7.
Sotoodehnia N, Siscovick DS, Vatta M, et al. "Beta2-adrenergic receptor genetic variants and risk of sudden cardiac death." Circulation. 2006;113(15):1842-8.
Stitziel NO, Khera AV, Wang X, et al. "ANGPTL3 Deficiency and Protection Against Coronary Artery Disease." J Am Coll Cardiol. 2017;69(16):2054-2063.
Suri FMK, Yamagishi K, Aleksic N, Hannan PJ, Folsom AR. "Novel hemostatic factor levels and risk of ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study." Cerebrovasc Dis. 2010;29(5):497-502.
Tandon A, Chen CJ, Penman A, et al. "African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans." Invest Ophthalmol Vis Sci. 2015;56(6):3999-4005.
Tang W, Yao L, Hoogeveen RC, et al. "The Association of Biomarkers of Inflammation and Extracellular Matrix Degradation With the Risk of Abdominal Aortic Aneurysm: The ARIC Study." Angiology. 2019;70(2):130-140.
Tang W, Teichert M, Chasman DI, et al. "A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium." Genet Epidemiol. 2013;37(5):512-521.
Taylor HA, Penman AD, Han H, et al. "Left ventricular architecture and survival in African-Americans free of coronary heart disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2007;99(10):1413-20.
Terry JG, Hinson WH, Evans GW, Schreiner PJ, Hagaman AP, Crouse JR. "Evaluation of magnetic resonance imaging for quantification of intraabdominal fat in human beings by spin-echo and inversion-recovery protocols." Am J Clin Nutr. 1995;62(2):297-301.
Thyagarajan B, Brott M, Mink P, et al. "CYP1B1 and CYP19 gene polymorphisms and breast cancer incidence: no association in the ARIC study." Cancer Lett. 2004;207(2):183-9.
Travis RC, Perez-Cornago A, Appleby PN, et al. "A Collaborative Analysis of Individual Participant Data from 19 Prospective Studies Assesses Circulating Vitamin D and Prostate Cancer Risk." Cancer Res. 2019;79(1):274-285.
Tsai AW, Cushman M, Tsai MY, et al. "Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2003;72(3):192-200.
Zakai NA, Lutsey PL, Folsom AR, Heckbert SR, Cushman M. "Total tissue factor pathway inhibitor and venous thrombosis. The Longitudinal Investigation of Thromboembolism Etiology." Thromb Haemost. 2010;104(2):207-12.
Zhao J, Zhu Y, Boerwinkle E. "Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.