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ARIC Publications

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Berndt SI, Gustafsson S, Mägi R, et al. "Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture." Nat Genet. 2013;45(5):501-12.
Mahajan A, Go MJin, Zhang W, et al. "Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility." Nat Genet. 2014;46(3):234-44.
Golden S H, Ding J, Szklo M, Schmidt M I, Duncan BB, Dobs A. "Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the atherosclerosis risk in communities study." Am J Epidemiol. 2004;160(6):540-8.
Li R, Boerwinkle E, Olshan AF, et al. "Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease." Atherosclerosis. 2000;149(2):451-62.
Selvin E, Coresh J, Golden SH, Brancati FL, Folsom AR, Steffes MW. "Glycemic control and coronary heart disease risk in persons with and without diabetes: the atherosclerosis risk in communities study." Arch Intern Med. 2005;165(16):1910-6.
Vitelli LL, Shahar E, Heiss G, et al. "Glycosylated hemoglobin level and carotid intimal-medial thickening in nondiabetic individuals. The Atherosclerosis Risk in Communities Study." Diabetes Care. 1997;20(9):1454-8.
Morrison AC, Doris PA, Folsom AR, Nieto FJ, Boerwinkle E. "G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke." Stroke. 2001;32(4):822-9.
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Gottesman RF, Cummiskey C, Chambless L, et al. "Hemostatic factors and subclinical brain infarction in a community-based sample: the ARIC study." Cerebrovasc Dis. 2009;28(6):589-94.
Zhu N, Pankow JS, Ballantyne CM, et al. "High-molecular-weight adiponectin and the risk of type 2 diabetes in the ARIC study." J Clin Endocrinol Metab. 2010;95(11):5097-104.
Cowan LT, Alonso A, Pankow JS, Folsom AR, Rosamond WD, Gottesman RF. "Hospitalized Infection as a Trigger for Acute Ischemic Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1612-7.
Marrone MT, Selvin E, Barber JR, Platz EA. "Hyperglycemia, Classified with Multiple Biomarkers Simultaneously in Men without Diabetes, and Risk of Fatal Prostate Cancer." Cancer Prev Res (Phila). 2019;12(2):103-112.
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Xu H, Zhang H, Yang W, et al. "Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children." Nat Commun. 2015;6:7553.
Cowan LT, Lutsey PL, Pankow JS, Matsushita K, Ishigami J. "Inpatient and Outpatient Infection as a Trigger of Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2018;7(22):e009683.
Bressler J, Fornage M, Hanis CL, et al. "The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts." BMC Med Genet. 2009;10:56.
Wu KK, Aleksic N, Ballantyne CM, Ahn C, Juneja H, Boerwinkle E. "Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease." Circulation. 2003;107(13):1729-32.
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Yamagishi K, Cushman M, Heckbert SR, Tsai MY, Folsom AR. "Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study." Br J Haematol. 2009;145(2):221-6.
Juraschek SP, Shantha GPalamaner, Chu AY, et al. "Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study." PLoS One. 2013;8(1):e55113.
Morris AP, Voight BF, Teslovich TM, et al. "Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes." Nat Genet. 2012;44(9):981-90.
Lindström S, Brody JA, Turman C, et al. "A large-scale exome array analysis of venous thromboembolism." Genet Epidemiol. 2019;43(4):449-457.
Taylor HA, Penman AD, Han H, et al. "Left ventricular architecture and survival in African-Americans free of coronary heart disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2007;99(10):1413-20.
Schmidt MI, Duncan BB, Vigo A, et al. "Leptin and incident type 2 diabetes: risk or protection?" Diabetologia. 2006;49(9):2086-96.
"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Dekker JM, Crow RS, Folsom AR, et al. "Low heart rate variability in a 2-minute rhythm strip predicts risk of coronary heart disease and mortality from several causes: the ARIC Study. Atherosclerosis Risk In Communities." Circulation. 2000;102(11):1239-44.
Duncan BB, Schmidt M I, Pankow JS, et al. "Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study." Diabetes. 2003;52(7):1799-805.
Oelsner EC, Balte PP, Bhatt SP, et al. "Lung function decline in former smokers and low-intensity current smokers: a secondary data analysis of the NHLBI Pooled Cohorts Study." Lancet Respir Med. 2020;8(1):34-44.
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Melnick SL, Shahar E, Folsom AR, et al. "Past infection by Chlamydia pneumoniae strain TWAR and asymptomatic carotid atherosclerosis. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Am J Med. 1993;95(5):499-504.
Zhao J, Zhu Y, Boerwinkle E. "Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
Lutsey PL, Folsom AR, Heckbert SR, Cushman M. "Peak thrombin generation and subsequent venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE) study." J Thromb Haemost. 2009;7(10):1639-48.
Xing C, Dupuis J. "Performance of statistical methods on CHARGE targeted sequencing data." BMC Genet. 2014;15:104.
Folsom AR, Tang W, Basu S, Misialek JR, Couper DJ, Heckbert SR. "Plasma Concentrations of High Molecular Weight Kininogen and Prekallikrein and Venous Thromboembolism Incidence in the General Population." Thromb Haemost. 2019;119(5):834-843.
Voight BF, Peloso GM, Orho-Melander M, et al. "Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study." Lancet. 2012;380(9841):572-80.
Aleksic N, Juneja H, Folsom AR, et al. "Platelet Pl(A2) allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study." Circulation. 2000;102(16):1901-5.
Ibrahim-Verbaas CA, Fornage M, Bis JC, et al. "Predicting stroke through genetic risk functions: the CHARGE Risk Score Project." Stroke. 2014;45(2):403-12.
Rawlings AM, Sharrett ARichey, Golden SH, Windham BG. "Prevalence and correlates of depressive symptoms in older adults across the glycaemic spectrum: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2018;35(5):583-587.
Sorlie PD, Nieto FJ, Adam E, Folsom AR, Shahar E, Massing M. "A prospective study of cytomegalovirus, herpes simplex virus 1, and coronary heart disease: the atherosclerosis risk in communities (ARIC) study." Arch Intern Med. 2000;160(13):2027-32.
Folsom AR, Cushman M, Heckbert SR, Rosamond WD, Aleksic N. "Prospective study of fibrinolytic markers and venous thromboembolism." J Clin Epidemiol. 2003;56(6):598-603.
Jehn ML, Guallar E, Clark JM, et al. "A prospective study of plasma ferritin level and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 2007;165(9):1047-54.
Folsom AR, Cushman M, Rasmussen-Torvik LJ, Heckbert SR, Tsai MY. "Prospective study of polymorphisms of the protein Z-dependent protease inhibitor and risk of venous thromboembolism." Thromb Haemost. 2007;97(3):493-4.
Aleksic N, Folsom AR, Cushman M, Heckbert SR, Tsai MY, Wu KK. "Prospective study of the A455V polymorphism in the thrombomodulin gene, plasma thrombomodulin, and incidence of venous thromboembolism: the LITE Study." J Thromb Haemost. 2003;1(1):88-94.
Folsom AR, Cushman M, Tsai MY, Heckbert SR, Aleksic N. "Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism." Am J Hematol. 2002;71(4):285-90.
Justice AE, Karaderi T, Highland HM, et al. "Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution." Nat Genet. 2019;51(3):452-469.
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Yatsuya H, Folsom AR, Yamagishi K, North KE, Brancati FL, Stevens J. "Race- and sex-specific associations of obesity measures with ischemic stroke incidence in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2010;41(3):417-25.
Sims R, van der Lee SJ, Naj AC, et al. "Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease." Nat Genet. 2017;49(9):1373-1384.
Reich D, Nalls MA, Kao LWH, et al. "Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene." PLoS Genet. 2009;5(1):e1000360.
Brown SA, Morrisett JD, Boerwinkle E, Hutchinson R, Patsch W. "The relation of lipoprotein[a] concentrations and apolipoprotein[a] phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb. 1993;13(11):1558-66.
Hallman MD, Brown SA, Ballantyne CM, A Sharrett R, Boerwinkle E. "Relationship between low-density lipoprotein subclasses and asymptomatic atherosclerosis in subjects from the Atherosclerosis Risk in Communities (ARIC) Study." Biomarkers. 2004;9(2):190-202.
Deal JA, Power MC, Palta P, et al. "Relationship of Cigarette Smoking and Time of Quitting with Incident Dementia and Cognitive Decline." J Am Geriatr Soc. 2020;68(2):337-345.
de Andrade M, Thandi I, Brown S, Gotto A, Patsch W, Boerwinkle E. "Relationship of the apolipoprotein E polymorphism with carotid artery atherosclerosis." Am J Hum Genet. 1995;56(6):1379-90.
He C, Chasman DI, Dreyfus J, et al. "Reproductive aging-associated common genetic variants and the risk of breast cancer." Breast Cancer Res. 2012;14(2):R54.
Simone B, De Stefano V, Leoncini E, et al. "Risk of venous thromboembolism associated with single and combined effects of Factor V Leiden, Prothrombin 20210A and Methylenetethraydrofolate reductase C677T: a meta-analysis involving over 11,000 cases and 21,000 controls." Eur J Epidemiol. 2013;28(8):621-47.
Elbein SC, Wang X, Karim MA, et al. "Role of a proline insertion in the insulin promoter factor 1 (IPF1) gene in African Americans with type 2 diabetes." Diabetes. 2006;55(10):2909-14.
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de Haan HG, A Vlieg vanHylckama, Lotta LA, et al. "Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes." J Thromb Haemost. 2018;16(12):2432-2441.
Sanders AE, Divaris K, Naorungroj S, Heiss G. "Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study." J Clin Periodontol. 2015;42(1):12-20.
Zakai NA, Lutsey PL, Folsom AR, Heckbert SR, Cushman M. "Total tissue factor pathway inhibitor and venous thrombosis. The Longitudinal Investigation of Thromboembolism Etiology." Thromb Haemost. 2010;104(2):207-12.
C Y Ng M, Saxena R, Li J, et al. "Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study." Diabetes. 2013;62(3):965-76.
Astor BC, Köttgen A, Hwang S-J, Bhavsar N, Fox CS, Coresh J. "Trefoil factor 3 predicts incident chronic kidney disease: a case-control study nested within the Atherosclerosis Risk in Communities (ARIC) study." Am J Nephrol. 2011;34(4):291-7.
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Nieto FJ, Iribarren C, Gross MD, Comstock GW, Cutler RG. "Uric acid and serum antioxidant capacity: a reaction to atherosclerosis?" Atherosclerosis. 2000;148(1):131-9.
Foster MC, Coresh JJ, Bonventre JV, et al. "Urinary Biomarkers and Risk of ESRD in the Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(11):1956-63.
McMahon GM, Hwang S-J, Clish CB, et al. "Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease." Kidney Int. 2017;91(6):1426-1435.
Köttgen A, Hwang S-J, Larson MG, et al. "Uromodulin levels associate with a common UMOD variant and risk for incident CKD." J Am Soc Nephrol. 2010;21(2):337-44.

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