ARIC Publications
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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture." Nat Genet. 2013;45(5):501-12.
"Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility." Nat Genet. 2014;46(3):234-44.
"Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the atherosclerosis risk in communities study." Am J Epidemiol. 2004;160(6):540-8.
"Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease." Atherosclerosis. 2000;149(2):451-62.
"Glycemic control and coronary heart disease risk in persons with and without diabetes: the atherosclerosis risk in communities study." Arch Intern Med. 2005;165(16):1910-6.
"Glycosylated hemoglobin level and carotid intimal-medial thickening in nondiabetic individuals. The Atherosclerosis Risk in Communities Study." Diabetes Care. 1997;20(9):1454-8.
"G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke." Stroke. 2001;32(4):822-9.
"Hemostatic factors and subclinical brain infarction in a community-based sample: the ARIC study." Cerebrovasc Dis. 2009;28(6):589-94.
"High-molecular-weight adiponectin and the risk of type 2 diabetes in the ARIC study." J Clin Endocrinol Metab. 2010;95(11):5097-104.
"Hospitalized Infection as a Trigger for Acute Ischemic Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1612-7.
"Hyperglycemia, Classified with Multiple Biomarkers Simultaneously in Men without Diabetes, and Risk of Fatal Prostate Cancer." Cancer Prev Res (Phila). 2019;12(2):103-112.
"Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV." Sci Rep. 2022;12(1):577.
"Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children." Nat Commun. 2015;6:7553.
"Inpatient and Outpatient Infection as a Trigger of Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2018;7(22):e009683.
"The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts." BMC Med Genet. 2009;10:56.
"Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease." Circulation. 2003;107(13):1729-32.
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Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study." Br J Haematol. 2009;145(2):221-6.
"Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study." PLoS One. 2013;8(1):e55113.
"Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes." Nat Genet. 2012;44(9):981-90.
"A large-scale exome array analysis of venous thromboembolism." Genet Epidemiol. 2019;43(4):449-457.
"Left ventricular architecture and survival in African-Americans free of coronary heart disease (from the Atherosclerosis Risk in Communities [ARIC] study)." Am J Cardiol. 2007;99(10):1413-20.
"Leptin and incident type 2 diabetes: risk or protection?" Diabetologia. 2006;49(9):2086-96.
""Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Low heart rate variability in a 2-minute rhythm strip predicts risk of coronary heart disease and mortality from several causes: the ARIC Study. Atherosclerosis Risk In Communities." Circulation. 2000;102(11):1239-44.
"Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study." Diabetes. 2003;52(7):1799-805.
"Lung function decline in former smokers and low-intensity current smokers: a secondary data analysis of the NHLBI Pooled Cohorts Study." Lancet Respir Med. 2020;8(1):34-44.
"Marginal additive hazards model for case-cohort studies with multiple disease outcomes: an application to the Atherosclerosis Risk in Communities (ARIC) study." Biostatistics. 2013;14(1):28-41.
"Matrix metalloproteinase-1 and tissue inhibitors do not predict incident coronary artery disease in the atherosclerosis risk in communities (ARIC) study." Tex Heart Inst J. 2008;35(4):388-94.
"Mendelian randomization of blood lipids for coronary heart disease." Eur Heart J. 2015;36(9):539-50.
"A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry." Nat Genet. 2013;45(6):690-6.
"Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans." Stroke. 2015;46(8):2063-8.
"Multi-ethnic genome-wide association study for atrial fibrillation." Nat Genet. 2018;50(9):1225-1233.
"Multiple imputation of missing data in nested case-control and case-cohort studies." Biometrics. 2018;74(4):1438-1449.
"Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule 1 (KIM-1) as predictors of incident CKD stage 3: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2012;60(2):233-40.
"No association between serum ferritin and asymptomatic carotid atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1995;141(8):719-23.
"Novel association between plasma matrix metalloproteinase-9 and risk of incident atrial fibrillation in a case-cohort study: the Atherosclerosis Risk in Communities study." PLoS One. 2013;8(3):e59052.
"Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels." Circ Cardiovasc Genet. 2014;7(2):144-50.
"Novel hemostatic factor levels and risk of ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) Study." Cerebrovasc Dis. 2010;29(5):497-502.
"Novel risk factors and the prediction of type 2 diabetes in the Atherosclerosis Risk in Communities (ARIC) study." Diabetes Care. 2013;36(1):70-6.
"Past infection by Chlamydia pneumoniae strain TWAR and asymptomatic carotid atherosclerosis. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Am J Med. 1993;95(5):499-504.
"Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
"Peak thrombin generation and subsequent venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE) study." J Thromb Haemost. 2009;7(10):1639-48.
"Performance of statistical methods on CHARGE targeted sequencing data." BMC Genet. 2014;15:104.
"Plasma Concentrations of High Molecular Weight Kininogen and Prekallikrein and Venous Thromboembolism Incidence in the General Population." Thromb Haemost. 2019;119(5):834-843.
"Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study." Lancet. 2012;380(9841):572-80.
"Platelet Pl(A2) allele and incidence of coronary heart disease: results from the Atherosclerosis Risk In Communities (ARIC) Study." Circulation. 2000;102(16):1901-5.
"Predicting stroke through genetic risk functions: the CHARGE Risk Score Project." Stroke. 2014;45(2):403-12.
"Prevalence and correlates of depressive symptoms in older adults across the glycaemic spectrum: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2018;35(5):583-587.
"A prospective study of cytomegalovirus, herpes simplex virus 1, and coronary heart disease: the atherosclerosis risk in communities (ARIC) study." Arch Intern Med. 2000;160(13):2027-32.
"Prospective study of fibrinolytic markers and venous thromboembolism." J Clin Epidemiol. 2003;56(6):598-603.
"A prospective study of plasma ferritin level and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 2007;165(9):1047-54.
"Prospective study of polymorphisms of the protein Z-dependent protease inhibitor and risk of venous thromboembolism." Thromb Haemost. 2007;97(3):493-4.
"Prospective study of the A455V polymorphism in the thrombomodulin gene, plasma thrombomodulin, and incidence of venous thromboembolism: the LITE Study." J Thromb Haemost. 2003;1(1):88-94.
"Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism." Am J Hematol. 2002;71(4):285-90.
"Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution." Nat Genet. 2019;51(3):452-469.
"Race- and sex-specific associations of obesity measures with ischemic stroke incidence in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2010;41(3):417-25.
"Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes." Am J Hum Genet. 2022;109(1):81-96.
"Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease." Nat Genet. 2017;49(9):1373-1384.
"Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene." PLoS Genet. 2009;5(1):e1000360.
"The relation of lipoprotein[a] concentrations and apolipoprotein[a] phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb. 1993;13(11):1558-66.
"Relationship between low-density lipoprotein subclasses and asymptomatic atherosclerosis in subjects from the Atherosclerosis Risk in Communities (ARIC) Study." Biomarkers. 2004;9(2):190-202.
"Relationship of Cigarette Smoking and Time of Quitting with Incident Dementia and Cognitive Decline." J Am Geriatr Soc. 2020;68(2):337-345.
"Relationship of the apolipoprotein E polymorphism with carotid artery atherosclerosis." Am J Hum Genet. 1995;56(6):1379-90.
"Reproductive aging-associated common genetic variants and the risk of breast cancer." Breast Cancer Res. 2012;14(2):R54.
"Risk of venous thromboembolism associated with single and combined effects of Factor V Leiden, Prothrombin 20210A and Methylenetethraydrofolate reductase C677T: a meta-analysis involving over 11,000 cases and 21,000 controls." Eur J Epidemiol. 2013;28(8):621-47.
"Role of a proline insertion in the insulin promoter factor 1 (IPF1) gene in African Americans with type 2 diabetes." Diabetes. 2006;55(10):2909-14.
"Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2003;72(3):192-200.
"Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations." PLoS Genet. 2017;13(5):e1006728.
"Soluble thrombomodulin as a predictor of incident coronary heart disease and symptomless carotid artery atherosclerosis in the Atherosclerosis Risk in Communities (ARIC) Study: a case-cohort study." Lancet. 1999;353(9166):1729-34.
"Stochastic curtailing and conditional power in matched case-control studies." Stat Med. 1994;13(5-7):663-70.
" "Targeted sequencing to identify novel genetic risk factors for deep vein thrombosis: a study of 734 genes." J Thromb Haemost. 2018;16(12):2432-2441.
"Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study." J Clin Periodontol. 2015;42(1):12-20.
"Total tissue factor pathway inhibitor and venous thrombosis. The Longitudinal Investigation of Thromboembolism Etiology." Thromb Haemost. 2010;104(2):207-12.
" " "Uric acid and serum antioxidant capacity: a reaction to atherosclerosis?" Atherosclerosis. 2000;148(1):131-9.
"Urinary Biomarkers and Risk of ESRD in the Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(11):1956-63.
"Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease." Kidney Int. 2017;91(6):1426-1435.
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