ARIC Publications
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Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition." JAMA. 2017;317(14):1443-1450.
"The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE." Neurology. 2016;87(5):473-80.
"Impact of differential attrition on the association of education with cognitive change over 20 years of follow-up: the ARIC neurocognitive study." Am J Epidemiol. 2014;179(8):956-66.
"Brain Aging in African-Americans: The Atherosclerosis Risk in Communities (ARIC) Experience." Curr Alzheimer Res. 2015;12(7):607-13.
"The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study." Diabetes. 2013;62(5):1763-7.
"Neuroimaging Correlates of Cerebral Microbleeds: The ARIC Study (Atherosclerosis Risk in Communities)." Stroke. 2017;48(11):2964-2972.
"Application of Latent Variable Methods to the Study of Cognitive Decline When Tests Change over Time." Epidemiology. 2015;26(6):878-87.
"Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium." Circ Cardiovasc Genet. 2014;7(3):321-331.
"Visual Function, Physical Function, and Activities of Daily Living in Two Aging Communities." Transl Vis Sci Technol. 2021;10(14):15.
" "Association between kidney disease measures and intracranial atherosclerosis: The ARIC study." Neurology. 2020;94(22):e2361-e2372.
"Associations of Left Atrial Function and Structure With Supraventricular Ectopy: The Multi-Ethnic Study of Atherosclerosis." J Am Heart Assoc. 2021;10(4):e018093.
"A genome-wide association study of depressive symptoms." Biol Psychiatry. 2013;73(7):667-78.
"Novel genetic loci associated with hippocampal volume." Nat Commun. 2017;8:13624.
"Associations of Peripheral Neuropathy Defined by Monofilament Insensitivity with Mild Cognitive Impairment and Dementia in Older Adults." Dement Geriatr Cogn Disord. 2022;51(2):150-158.
"Associations of Cardiac, Kidney, and Diabetes Biomarkers With Peripheral Neuropathy among Older Adults in the Atherosclerosis Risk in Communities (ARIC) Study." Clin Chem. 2020;66(5):686-696.
"Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nat Genet. 2017;49(3):426-432.
"Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults." Nat Commun. 2020;11(1):4796.
"Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
" " "Predicting stroke through genetic risk functions: the CHARGE Risk Score Project." Stroke. 2014;45(2):403-12.
"Age-related macular degeneration and long-term risk of stroke subtypes." Stroke. 2012;43(6):1681-3.
"A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans." J Cardiovasc Electrophysiol. 2014;25(11):1150-7.
"Long-chain monounsaturated Fatty acids and incidence of congestive heart failure in 2 prospective cohorts." Circulation. 2013;127(14):1512-21, 1521e1-18.
"Cardiac Structure and Function and Diabetes-Related Risk of Death or Heart Failure in Older Adults." J Am Heart Assoc. 2022;11(6):e022308.
"Association of Left Atrial Structure and Function With Heart Failure in Older Adults." J Am Coll Cardiol. 2022;79(16):1549-1561.
" "Incidence of and risk factors for sick sinus syndrome in the general population." J Am Coll Cardiol. 2014;64(6):531-8.
"Novel Genetic Loci Associated With Retinal Microvascular Diameter." Circ Cardiovasc Genet. 2016;9(1):45-54.
"Genome-wide association study of retinopathy in individuals without diabetes." PLoS One. 2013;8(2):e54232.
"Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2022;350:82-89.
"Relation of Diabetes Mellitus to Incident Dementia in Patients With Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2022;165:51-57.
"Associations of Echocardiography Markers and Vascular Brain Lesions: The ARIC Study." J Am Heart Assoc. 2018;7(24):e008992.
"Associations Between Left Ventricular Structure, Function, and Cerebral Amyloid: The ARIC-PET Study." Stroke. 2019;50(12):3622-3624.
"Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study." JAMA Neurol. 2018;75(11):1375-1382.
"Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
"Performance of non-traditional hyperglycemia biomarkers by chronic kidney disease status in older adults with diabetes: Results from the Atherosclerosis Risk in Communities Study." J Diabetes. 2018;10(4):276-285.
"Subclinical Cardiovascular Disease and Fall Risk in Older Adults: Results From the Atherosclerosis Risk in Communities Study." J Am Geriatr Soc. 2019;67(9):1795-1802.
"Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
"Are Trends in Hospitalization Prior to Hospice Use Associated With Hospice Episode Characteristics?" Am J Hosp Palliat Care. 2017;34(9):860-868.
"Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
"Short-Term Prognostic Impact of Arterial Stiffness in Older Adults Without Prevalent Cardiovascular Disease." Hypertension. 2019;74(6):1373-1382.
"Associations Between Kidney Disease Measures and Regional Pulse Wave Velocity in a Large Community-Based Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(5):682-690.
"Association of common genetic variants with brain microbleeds: A genome-wide association study." Neurology. 2020;95(24):e3331-e3343.
"Midlife vascular risk factors and midlife cognitive status in relation to prevalence of mild cognitive impairment and dementia in later life: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2018;14(11):1406-1415.
"Vascular imaging abnormalities and cognition: mediation by cortical volume in nondemented individuals: atherosclerosis risk in communities-neurocognitive study." Stroke. 2015;46(2):433-40.
"Temporal Trends and Prognosis of Physical Examination Findings in Patients With Acute Decompensated Heart Failure: The ARIC Study Community Surveillance." Circ Heart Fail. 2021;14(12):e008403.
"Uromodulin levels associate with a common UMOD variant and risk for incident CKD." J Am Soc Nephrol. 2010;21(2):337-44.
"Conventional and Novel Lipid Measures and Risk of Peripheral Artery Disease." Arterioscler Thromb Vasc Biol. 2021;41(3):1229-1238.
"Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations." PLoS Genet. 2019;15(12):e1008500.
"Homocysteine and Incident Atrial Fibrillation: The Atherosclerosis Risk in Communities Study and the Multi-Ethnic Study of Atherosclerosis." Heart Lung Circ. 2019;28(4):615-622.
"Association of Educational Attainment With Lifetime Risk of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Intern Med. 2017;177(8):1165-1172.
"Loneliness and its predictors among older adults prior to and during the COVID-19 pandemic: cross-sectional and longitudinal survey findings from participants of the Atherosclerosis Risk in Communities (ARIC) Study cohort in the USA." BMJ Open. 2021;11(12):e053542.
"Operationalizing Frailty in the Atherosclerosis Risk in Communities Study Cohort." J Gerontol A Biol Sci Med Sci. 2017;72(3):382-388.
"Association of Influenza-like Illness Activity With Hospitalizations for Heart Failure: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(4):363-369.
"Severe Hypoglycemia and Elevated High-Sensitivity Cardiac Troponin T in Older Adults With Diabetes: The ARIC Study." J Am Coll Cardiol. 2016;68(12):1370-1.
"Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS)." Int J Mol Sci. 2019;20(7).
"Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders." Am J Hum Genet. 2018;103(5):691-706.
"Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):335-43.
"Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource." Diabetologia. 2012;55(11):2970-84.
"Central and peripheral pulse wave velocity and subclinical myocardial stress and damage in older adults." PLoS One. 2019;14(2):e0212892.
"An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis." Nat Commun. 2019;10(1):2581.
"Prediabetes and Diabetes Are Associated With Arterial Stiffness in Older Adults: The ARIC Study." Am J Hypertens. 2016;29(9):1038-45.
"ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):350-8.
"Nine-Year Ethanol Intake Trajectories and Their Association With 15-Year Cognitive Decline Among Black and White Adults." Am J Epidemiol. 2020;189(8):788-800.
"SES and correlated factors do not explain the association between periodontal disease, edentulism, and cancer risk." Ann Epidemiol. 2019;38:35-41.
"Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
"Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese." J Am Coll Cardiol. 2014;63(12):1200-1210.
"Independent susceptibility markers for atrial fibrillation on chromosome 4q25." Circulation. 2010;122(10):976-84.
"The genomics of heart failure: design and rationale of the HERMES consortium." ESC Heart Fail. 2021;8(6):5531-5541.
"Short-term Variability of Vitamin D-Related Biomarkers." Clin Chem. 2016;62(12):1647-1653.
" "Biological knowledge-driven analysis of epistasis in human GWAS with application to lipid traits." Methods Mol Biol. 2015;1253:35-45.
"Lipoprotein lipase variants interact with polyunsaturated fatty acids for obesity traits in women: replication in two populations." Nutr Metab Cardiovasc Dis. 2014;24(12):1323-9.
"Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium." Circ Cardiovasc Genet. 2014;7(3):365-73.
"Refining Prediction of Atrial Fibrillation-Related Stroke Using the P-CHADS-VASc Score." Circulation. 2019;139(2):180-191.
"Relationship Between Domain-Specific Cognitive Function and Speech-in-Noise Performance in Older Adults: The Atherosclerosis Risk in Communities Hearing Pilot Study." Am J Audiol. 2019;28(4):1006-1014.
"Meta-analysis of epigenome-wide association studies of cognitive abilities." Mol Psychiatry. 2018;23(11):2133-2144.
"Ankle-brachial index and physical function in older individuals: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2017;257:208-215.
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