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ARIC Publications

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Journal Article
Fowkes FGR, Murray GD, Butcher I, et al. "Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events." Eur J Prev Cardiol. 2014;21(3):310-20.
Schneider ALC, Kalyani RR, Golden S, et al. "Diabetes and Prediabetes and Risk of Hospitalization: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):772-9.
Mongraw-Chaffin ML, Matsushita K, Brancati FL, et al. "Diabetes medication use and blood lactate level among participants with type 2 diabetes: the atherosclerosis risk in communities carotid MRI study." PLoS One. 2012;7(12):e51237.
Cheng S, Gupta DK, Claggett B, et al. "Differential influence of distinct components of increased blood pressure on cardiovascular outcomes: from the atherosclerosis risk in communities study." Hypertension. 2013;62(3):492-8.
Bhatt SP, Balte PP, Schwartz JE, et al. "Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality." JAMA. 2019;321(24):2438-2447.
Soliman EZ, Prineas RJ, Case DL, et al. "Electrocardiographic and clinical predictors separating atherosclerotic sudden cardiac death from incident coronary heart disease." Heart. 2011;97(19):1597-601.
Miedema MD, Norby FL, Blaha MJ, Virani SS, Coresh JJ, Ballantyne CM. "Eligibility for statin therapy according to new cholesterol guidelines and prevalent use of medication to lower lipid levels in an older US Cohort: the Atherosclerosis Risk in Communities Study Cohort." JAMA Intern Med. 2015;175(1):138-40.
Yende S, Alvarez K, Loehr LR, et al. "Epidemiology and long-term clinical and biologic risk factors for pneumonia in community-dwelling older Americans: analysis of three cohorts." Chest. 2013;144(3):1008-1017.
Yeung EH, Saudek CD, Jahren HA, et al. "Evaluation of a novel isotope biomarker for dietary consumption of sweets." Am J Epidemiol. 2010;172(9):1045-52.
Weng L-C, Roetker NS, Lutsey PL, et al. "Evaluation of the relationship between plasma lipids and abdominal aortic aneurysm: A Mendelian randomization study." PLoS One. 2018;13(4):e0195719.
Spracklen CN, Karaderi T, Yaghootkar H, et al. "Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.
Rawlings AM, Bandeen-Roche K, Gross AL, et al. "Factor structure of the ARIC-NCS Neuropsychological Battery: An evaluation of invariance across vascular factors and demographic characteristics." Psychol Assess. 2016;28(12):1674-1683.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Fifteen-Year Trends in Management and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Among Black and White Patients: The ARIC Community Surveillance Study, 2000-2014." J Am Heart Assoc. 2018;7(19):e010203.
Gong J, Schumacher F, Lim U, et al. "Fine Mapping and Identification of BMI Loci in African Americans." Am J Hum Genet. 2013;93(4):661-71.
Boerwinkle E. "Following-up genome-wide association study signals: lessons learned from Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):332-4.
Rooney MR, Norby FL, Maheshwari A, et al. "Frequent Premature Atrial Contractions Are Associated With Poorer Cognitive Function in the Atherosclerosis Risk in Communities (ARIC) Study." Mayo Clin Proc. 2021;96(5):1147-1156.
Yoneyama S, Guo Y, Lanktree MB, et al. "Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations." Hum Mol Genet. 2014;23(9):2498-510.
Evangelou E, Warren HR, Mosen-Ansorena D, et al. "Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
Davies G, Armstrong N, Bis JC, et al. "Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949)." Mol Psychiatry. 2015;20(2):183-92.
Hofer E, Roshchupkin GV, Adams HHH, et al. "Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults." Nat Commun. 2020;11(1):4796.
Hobbs BD, de Jong K, Lamontagne M, et al. "Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nat Genet. 2017;49(3):426-432.
Sim X, Jensen RA, M Ikram K, et al. "Genetic loci for retinal arteriolar microcirculation." PLoS One. 2013;8(6):e65804.
Traylor M, Malik R, Nalls MA, et al. "Genetic variation at 16q24.2 is associated with small vessel stroke." Ann Neurol. 2017;81(3):383-394.
Blue EE, Bis JC, Dorschner MO, et al. "Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project." Dement Geriatr Cogn Disord. 2018;45(1-2):1-17.
Ligthart S, Vaez A, Võsa U, et al. "Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders." Am J Hum Genet. 2018;103(5):691-706.
van Loon J, Dehghan A, Weihong T, et al. "Genome-wide association studies identify genetic loci for low von Willebrand factor levels." Eur J Hum Genet. 2016;24(7):1035-40.
Fornage M, Debette S, Bis JC, et al. "Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium." Ann Neurol. 2011;69(6):928-39.
Hek K, Demirkan A, Lahti J, et al. "A genome-wide association study of depressive symptoms." Biol Psychiatry. 2013;73(7):667-78.
Guan W, Steffen BT, Lemaitre RN, et al. "Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium." Circ Cardiovasc Genet. 2014;7(3):321-331.
Jensen RA, Sim X, Li X, et al. "Genome-wide association study of retinopathy in individuals without diabetes." PLoS One. 2013;8(2):e54232.
Jones G, Trajanoska K, Santanasto AJ, et al. "Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
Debette S, Verbaas CAIbrahim, Bressler J, et al. "Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium." Biol Psychiatry. 2015;77(8):749-63.
Morrison AC, Felix JF, L Cupples A, et al. "Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium." Circ Cardiovasc Genet. 2010;3(3):248-55.
Waks JW, Sitlani CM, Soliman EZ, et al. "Global Electric Heterogeneity Risk Score for Prediction of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies." Circulation. 2016;133(23):2222-34.
"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017." Lancet. 2018;392(10159):1789-1858.
Bell EJ, Selvin E, Lutsey PL, Nambi V, Cushman M. "Glycemia (hemoglobin A1c) and incident venous thromboembolism in the Atherosclerosis Risk in Communities cohort study." Vasc Med. 2013;18(5):245-50.
Tanaka H, Palta P, Folsom AR, et al. "Habitual physical activity and central artery stiffening in older adults: the Atherosclerosis Risk in Communities study." J Hypertens. 2018;36(9):1889-1894.
Oelsner EC, Balte PP, Cassano PA, et al. "Harmonization of Respiratory Data From 9 US Population-Based Cohorts: The NHLBI Pooled Cohorts Study." Am J Epidemiol. 2018;187(11):2265-2278.
Deal JA, Sharrett ARichey, Albert MS, et al. "Hearing impairment and cognitive decline: a pilot study conducted within the atherosclerosis risk in communities neurocognitive study." Am J Epidemiol. 2015;181(9):680-90.
Deal JA, Sharrett ARichey, Bandeen-Roche K, Kritchevsky SB, Pompeii LA, B Windham G. "Hearing Impairment and Physical Function and Falls in the Atherosclerosis Risk in Communities Hearing Pilot Study." J Am Geriatr Soc. 2016;64(4):906-8.
Witt LS, Rotter J, Stearns SC, et al. "Heart Failure and Cognitive Impairment in the Atherosclerosis Risk in Communities (ARIC) Study." J Gen Intern Med. 2018;33(10):1721-1728.
Shah AM, Claggett B, Loehr LR, et al. "Heart Failure Stages Among Older Adults in the Community: The Atherosclerosis Risk in Communities Study." Circulation. 2017;135(3):224-240.
Fyfe-Johnson AL, Muller CJ, Alonso A, et al. "Heart Rate Variability and Incident Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1452-8.
Tanaka H, Heiss G, McCabe EL, et al. "Hemodynamic Correlates of Blood Pressure in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." J Clin Hypertens (Greenwich). 2016;18(12):1222-1227.
Ebong IA, Wilson MD, Bertoni AG, et al. "High-sensitivity cardiac troponin T and the risk of heart failure in postmenopausal women of the ARIC Study." Menopause. 2021;28(3):284-291.
Kubota Y, Alonso A, Heckbert SR, Norby FL. "Homocysteine and Incident Atrial Fibrillation: The Atherosclerosis Risk in Communities Study and the Multi-Ethnic Study of Atherosclerosis." Heart Lung Circ. 2019;28(4):615-622.
Wong E, Ballew SH, Daya N, et al. "Hospitalization Risk among Older Adults with Chronic Kidney Disease." Am J Nephrol. 2019;50(3):212-220.
Cowan LT, Alonso A, Pankow JS, Folsom AR, Rosamond WD, Gottesman RF. "Hospitalized Infection as a Trigger for Acute Ischemic Stroke: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1612-7.
Ong Y-T, Wong TY, Klein R, et al. "Hypertensive retinopathy and risk of stroke." Hypertension. 2013;62(4):706-11.
Sengeløv M, Cheng S, Biering-Sørensen T, et al. "Ideal Cardiovascular Health and the Prevalence and Severity of Aortic Stenosis in Elderly Patients." J Am Heart Assoc. 2018;7(3).
Shah AM, Claggett B, Folsom AR, Lutsey PL, Ballantyne CM, Heiss G. "Ideal Cardiovascular Health During Adult Life and Cardiovascular Structure and Function Among the Elderly." Circulation. 2015;132(21):1979-89.
"Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies." Lancet Neurol. 2016;15(7):695-707.
Corona G, Rastrelli G, Silverii A, et al. "The identification of prediabetes condition with ARIC algorithm predicts long-term CV events in patients with erectile dysfunction." J Sex Med. 2013;10(4):1114-23.
Gottesman RF, Rawlings AM, Sharrett ARichey, et al. "Impact of differential attrition on the association of education with cognitive change over 20 years of follow-up: the ARIC neurocognitive study." Am J Epidemiol. 2014;179(8):956-66.
Miedema MD, Norby FL, Blaha MJ, Virani SS, Coresh JJ, Ballantyne CM. "Implications of the Eighth Joint National Committee Guidelines for the Management of High Blood Pressure for Aging Adults: Atherosclerosis Risk in Communities Study." Hypertension. 2015;66(3):474-80.
Jensen PN, Gronroos NN, Chen LYee, Folsom AR, deFilippi C, Heckbert SR. "Incidence of and risk factors for sick sinus syndrome in the general population." J Am Coll Cardiol. 2014;64(6):531-8.
Gurka MJ, Golden SH, Musani SK, et al. "Independent associations between a metabolic syndrome severity score and future diabetes by sex and race: the Atherosclerosis Risk In Communities Study and Jackson Heart Study." Diabetologia. 2017;60(7):1261-1270.
Lubitz SA, Sinner MF, Lunetta KL, et al. "Independent susceptibility markers for atrial fibrillation on chromosome 4q25." Circulation. 2010;122(10):976-84.
Graff M, Gordon-Larsen P, Lim U, et al. "The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study." Diabetes. 2013;62(5):1763-7.
Bick AG, Weinstock JS, Nandakumar SK, et al. "Inherited causes of clonal haematopoiesis in 97,691 whole genomes." Nature. 2020;586(7831):763-768.
Liu J, Carnero-Montoro E, van Dongen J, et al. "An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis." Nat Commun. 2019;10(1):2581.
Rosenthal EA, Ranchalis J, Crosslin DR, et al. "Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia." Am J Hum Genet. 2013;93(6):1035-45.
Matsushita K, Kwak L, Sang Y, et al. "Kidney Disease Measures and Left Ventricular Structure and Function: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2017;6(9).
Secora A, G Alexander C, Ballew SH, Coresh JJ. "Kidney Function, Polypharmacy, and Potentially Inappropriate Medication Use in a Community-Based Cohort of Older Adults." Drugs Aging. 2018;35(8):735-750.
Gonçalves A, Hung C-L, Claggett B, et al. "Left Atrial Structure and Function Across the Spectrum of Cardiovascular Risk in the Elderly: The Atherosclerosis Risk in Communities Study." Circ Cardiovasc Imaging. 2016;9(2):e004010.
Power MC, Schneider ALC, Wruck L, et al. "Life-course blood pressure in relation to brain volumes." Alzheimers Dement. 2016;12(8):890-9.
Tang W, Yao L, Roetker NS, et al. "Lifetime Risk and Risk Factors for Abdominal Aortic Aneurysm in a 24-Year Prospective Study: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2016;36(12):2468-2477.
Mou L, Norby FL, Chen LYee, et al. "Lifetime Risk of Atrial Fibrillation by Race and Socioeconomic Status: ARIC Study (Atherosclerosis Risk in Communities)." Circ Arrhythm Electrophysiol. 2018;11(7):e006350.
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
Barral S, Cheng R, Reitz C, et al. "Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease." Alzheimers Dement. 2015;11(12):1397-1406.
Ma Y, Tucker KL, Smith CE, et al. "Lipoprotein lipase variants interact with polyunsaturated fatty acids for obesity traits in women: replication in two populations." Nutr Metab Cardiovasc Dis. 2014;24(12):1323-9.
"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Imamura F, Lemaitre RN, King IB, et al. "Long-chain monounsaturated Fatty acids and incidence of congestive heart failure in 2 prospective cohorts." Circulation. 2013;127(14):1512-21, 1521e1-18.
Wu A, Coresh JJ, Selvin E, et al. "Lower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community." J Am Heart Assoc. 2017;6(1).
Yong F, Heiss G, Couper DJ, Meyer ML, Cheng S. "Measurement Repeatability of Central and Peripheral Blood Pressures: The ARIC Study." Am J Hypertens. 2017;30(10):978-984.
Ellinor PT, Lunetta KL, Albert CM, et al. "Meta-analysis identifies six new susceptibility loci for atrial fibrillation." Nat Genet. 2012;44(6):670-5.
de Vries PS, Chasman DI, Sabater-Lleal M, et al. "A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration." Hum Mol Genet. 2016;25(2):358-70.
Marioni RE, McRae AF, Bressler J, et al. "Meta-analysis of epigenome-wide association studies of cognitive abilities." Mol Psychiatry. 2018;23(11):2133-2144.
Walker KA, Power MC, Hoogeveen RC, et al. "Midlife Systemic Inflammation, Late-Life White Matter Integrity, and Cerebral Small Vessel Disease: The Atherosclerosis Risk in Communities Study." Stroke. 2017;48(12):3196-3202.
Knopman DS, Gottesman RF, Sharrett ARichey, et al. "Midlife vascular risk factors and midlife cognitive status in relation to prevalence of mild cognitive impairment and dementia in later life: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2018;14(11):1406-1415.

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