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ARIC Publications

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Tang O, Matsushita K, Coresh JJ, et al. "Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
Knopman DS, Gottesman RF, Sharrett ARichey, et al. "Midlife vascular risk factors and midlife cognitive status in relation to prevalence of mild cognitive impairment and dementia in later life: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2018;14(11):1406-1415.
Jia X, Sun C, Nambi V, et al. "Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2022;350:82-89.
Palta P, Griswold M, Ranadive R, et al. "Midlife Cardiovascular Health and Robust Versus Frail Late-Life Status: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2022;77(6):1222-1229.
Ballantyne CM, Hoogeveen RC, McNeill AM, et al. "Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study." Int J Obes (Lond). 2008;32 Suppl 2(Suppl 2):S21-4.
Dehghan A, Dupuis J, Barbalic M, et al. "Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels." Circulation. 2011;123(7):731-8.
Yoshida Y, Chen Z, Baudier RL, et al. "Menopausal hormone therapy and risk of cardiovascular events in women with prediabetes or type 2 diabetes: A pooled analysis of 2917 postmenopausal women." Atherosclerosis. 2022;344:13-19.
Yong F, Heiss G, Couper DJ, Meyer ML, Cheng S. "Measurement Repeatability of Central and Peripheral Blood Pressures: The ARIC Study." Am J Hypertens. 2017;30(10):978-984.
van der Velde M, Matsushita K, Coresh J, et al. "Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts." Kidney Int. 2011;79(12):1341-52.
Folsom AR, Ma J, Eckfeldt JH, Nieto FJ, Metcalf PA, Barnes RW. "Low serum albumin. Association with diabetes mellitus and other cardiovascular risk factors but not with prevalent cardiovascular disease or carotid artery intima-media thickness. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Ann Epidemiol. 1995;5(3):186-91.
Aggarwal V, Schneider ALC, Selvin E. "Low hemoglobin A(1c) in nondiabetic adults: an elevated risk state?" Diabetes Care. 2012;35(10):2055-60.
Petruski-Ivleva N, Viera AJ, Shimbo D, et al. "Longitudinal Patterns of Change in Systolic Blood Pressure and Incidence of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." Hypertension. 2016;67(6):1150-6.
Folsom AR, Lutsey PL, Heckbert SR, et al. "Longitudinal increases in blood biomarkers of inflammation or cardiovascular disease and the incidence of venous thromboembolism." J Thromb Haemost. 2018;16(10):1964-1972.
Monda KL, Ballantyne CM, North KE. "Longitudinal impact of physical activity on lipid profiles in middle-aged adults: the Atherosclerosis Risk in Communities Study." J Lipid Res. 2009;50(8):1685-91.
Wang SY, Tan ASL, Claggett B, et al. "Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(12):1203-1212.
Ganesh SK, Tragante V, Guo W, et al. "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.
Saeed A, Sun W, Agarwala A, et al. "Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
Pokharel Y, Sun W, Polfus LM, et al. "Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study." Atherosclerosis. 2015;241(2):641-8.
Ma Y, Floyd JS, Austin TR, et al. "Life's Simple 7 Cardiovascular Health Score in Relation to Arrhythmias on Extended Ambulatory Electrocardiographic Monitoring (from the Multi-Ethnic Study of Atherosclerosis)." Am J Cardiol. 2022;170:63-70.
Commodore-Mensah Y, Mok Y, Gottesman RF, et al. "Life's Simple 7 at Midlife and Risk of Recurrent Cardiovascular Disease and Mortality after Stroke: The ARIC study." J Stroke Cerebrovasc Dis. 2022;31(7):106486.
Xiao Q, Heiss G, Kucharska-Newton A, Bey G, Love S-AM, Whitsel EA. "Life-Course Neighborhood Socioeconomic Status and Cardiovascular Events in Black and White Adults in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2022;191(8):1470-1484.
Gondalia R, Holliday KM, Baldassari A, et al. "Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
Gonçalves A, Hung C-L, Claggett B, et al. "Left Atrial Structure and Function Across the Spectrum of Cardiovascular Risk in the Elderly: The Atherosclerosis Risk in Communities Study." Circ Cardiovasc Imaging. 2016;9(2):e004010.
Ellis J, Lange EM, Li J, et al. "Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans." Hum Genet. 2014;133(8):985-95.
Grams ME, Surapaneni A, Ballew SH, et al. " Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis." J Am Soc Nephrol. 2019;30(10):2027-2036.
Alexander N, Matsushita K, Sang Y, Ballew S, Mahmoodi BK, Astor BC. "Kidney measures with diabetes and hypertension on cardiovascular disease: the Atherosclerosis Risk in Communities Study." Am J Nephrol. 2015;41(4-5):409-17.
Mok Y, Ballew SH, Bash LD, et al. "International Validation of the Thrombolysis in Myocardial Infarction (TIMI) Risk Score for Secondary Prevention in Post-MI Patients: A Collaborative Analysis of the Chronic Kidney Disease Prognosis Consortium and the Risk Validation Scientific Committee." J Am Heart Assoc. 2018;7(14).
Huan T, Nguyen S, Colicino E, et al. "Integrative analysis of clinical and epigenetic biomarkers of mortality." Aging Cell. 2022;21(6):e13608.
Cowan LT, Lutsey PL, Pankow JS, Matsushita K, Ishigami J. "Inpatient and Outpatient Infection as a Trigger of Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2018;7(22):e009683.
E Estes H, Zhang Z-M, Li Y, Tereshchenko LG. "Individual components of the Romhilt-Estes left ventricular hypertrophy score differ in their prediction of cardiovascular events: The Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2015;170(6):1220-6.
Ishigami J, Cowan LT, Demmer RT, et al. "Incident Hospitalization with Major Cardiovascular Diseases and Subsequent Risk of ESKD: Implications for Cardiorenal Syndrome." J Am Soc Nephrol. 2020;31(2):405-414.
Adeniyi A, Folsom AR, Brancati FL, Desvorieux M, Pankow JS, Taylor H. "Incidence and risk factors for cardiovascular disease in African Americans with diabetes: the Atherosclerosis Risk in Communities (ARIC) study." J Natl Med Assoc. 2002;94(12):1025-35.
Rywik SL, Williams OD, Pajak A, et al. "Incidence and correlates of hypertension in the Atherosclerosis Risk in Communities (ARIC) study and the Monitoring Trends and Determinants of Cardiovascular Disease (POL-MONICA) project." J Hypertens. 2000;18(8):999-1006.
Folsom AR, Burke GL, Byers CL, et al. "Implications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies." Am J Clin Nutr. 1991;53(6 Suppl):1604S-1611S.
Han E, Truesdale KP, Taber DR, Cai J, Juhaeri J, Stevens J. "Impact of overweight and obesity on hospitalization: race and gender differences." Int J Obes (Lond). 2009;33(2):249-56.
Ogunwale AN, Morrison AC, Sun W, et al. "The impact of multiple single day blood pressure readings on cardiovascular risk estimation: The Atherosclerosis Risk in Communities study." Eur J Prev Cardiol. 2016;23(14):1529-36.
Huxley RR, Yatsuya H, Lutsey PL, Woodward M, Alonso A, Folsom AR. "Impact of age at smoking initiation, dosage, and time since quitting on cardiovascular disease in african americans and whites: the atherosclerosis risk in communities study." Am J Epidemiol. 2012;175(8):816-26.
Corona G, Rastrelli G, Silverii A, et al. "The identification of prediabetes condition with ARIC algorithm predicts long-term CV events in patients with erectile dysfunction." J Sex Med. 2013;10(4):1114-23.
Rasmussen-Torvik LJ, Shay CM, Abramson JG, et al. "Ideal cardiovascular health is inversely associated with incident cancer: the Atherosclerosis Risk In Communities study." Circulation. 2013;127(12):1270-5.
Shah AM, Claggett B, Folsom AR, Lutsey PL, Ballantyne CM, Heiss G. "Ideal Cardiovascular Health During Adult Life and Cardiovascular Structure and Function Among the Elderly." Circulation. 2015;132(21):1979-89.
Oyenuga AO, Folsom AR, Cheng S, Tanaka H. "Greater Adherence to Life's Simple 7 Is Associated With Less Arterial Stiffness: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2019;32(8):769-776.
Selvin E, Coresh J, Golden SH, Boland LL, Brancati FL, Steffes MW. "Glycemic control, atherosclerosis, and risk factors for cardiovascular disease in individuals with diabetes: the atherosclerosis risk in communities study." Diabetes Care. 2005;28(8):1965-73.
Selvin E, Steffes MW, Zhu H, et al. "Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults." N Engl J Med. 2010;362(9):800-11.
Huan T, Joehanes R, Song C, et al. "Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease." Nat Commun. 2019;10(1):4267.
Köttgen A, Kao W HL, Hwang S-J, et al. "Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies." BMC Med Genet. 2008;9:49.
Maruthur NM, Li M, Halushka MK, et al. "Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study." PLoS One. 2015;10(6):e0128452.
Schunk SJ, Kleber ME, März W, et al. "Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality." Eur Heart J. 2021;42(18):1742-1756.
Seidelmann SB, Feofanova E, Yu B, et al. "Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk." J Am Coll Cardiol. 2018;72(15):1763-1773.
Ehret GB, Munroe PB, Rice KM, et al. "Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk." Nature. 2011;478(7367):103-9.
Li C, Grove ML, Yu B, Jones BC, Morrison A, Boerwinkle E. "Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population." Hum Genet. 2018;137(1):85-94.
Allen NB, Lloyd-Jones D, Hwang S-J, et al. "Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies." Am Heart J. 2016;175:112-20.
Weng L-C, Tang W, Rich SS, et al. "A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups." Thromb Res. 2014;134(2):462-7.
Evangelou E, Warren HR, Mosen-Ansorena D, et al. "Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
Yazdani A, Yazdani A, Samiei A. "Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data." J Biomed Inform. 2016;60:114-9.
Sitlani CM, Rice KM, Lumley T, et al. "Generalized estimating equations for genome-wide association studies using longitudinal phenotype data." Stat Med. 2015;34(1):118-30.
Savoca MR, Steffen LM, Bertoni AG. "From Neighborhood to Genome: Three Decades of Nutrition-Related Research from the Atherosclerosis Risk in Communities Study." J Acad Nutr Diet. 2017;117(12):1881-1886.e10.
Rapsomaniki E, White IR, Wood AM, Thompson SG. "A framework for quantifying net benefits of alternative prognostic models." Stat Med. 2012;31(2):114-30.
Evans DS, Avery CL, Nalls MA, et al. "Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans." Hum Mol Genet. 2016;25(19):4350-4368.
Honda Y, Mok Y, Ishigami J, et al. "The Fifth-Generation Cardiac Troponin T and Cardiovascular Disease in the Community." J Am Coll Cardiol. 2021;78(20):2019-2021.
Lutsey PL, Alonso A, Selvin E, et al. "Fibroblast growth factor-23 and incident coronary heart disease, heart failure, and cardiovascular mortality: the Atherosclerosis Risk in Communities study." J Am Heart Assoc. 2014;3(3):e000936.
Nabulsi AA, Folsom AR, Heiss G, et al. "Fasting hyperinsulinemia and cardiovascular disease risk factors in nondiabetic adults: stronger associations in lean versus obese subjects. Atherosclerosis Risk in Communities Study Investigators." Metabolism. 1995;44(7):914-22.
George KM, Folsom AR, Kucharska-Newton AMaria, Mosley TH. "Factors Related to Differences in Retention among African American and White Participants in the Atherosclerosis Risk in Communities Study (ARIC) Prospective Cohort: 1987-2013." Ethn Dis. 2017;27(1):31-38.
Buyske S, Wu Y, Carty CL, et al. "Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study." PLoS One. 2012;7(4):e35651.
Barrett JK, Huille R, Parker R, Yano Y. "Estimating the association between blood pressure variability and cardiovascular disease: An application using the ARIC Study." Stat Med. 2019;38(10):1855-1868.
Matsushita K, Coresh JJ, Sang Y, et al. "Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data." Lancet Diabetes Endocrinol. 2015;3(7):514-25.
Srinath R, Golden SHill, Carson KA. "Endogenous testosterone and its relationship to preclinical and clinical measures of cardiovascular disease in the atherosclerosis risk in communities study." J Clin Endocrinol Metab. 2015;100(4):1602-8.
Cowan LT, Lakshminarayan K, Lutsey PL, Beck J, Offenbacher S. "Endodontic therapy and incident cardiovascular disease: The Atherosclerosis Risk in Communities (ARIC) study." J Public Health Dent. 2020;80(1):79-91.
Rautaharju PM, Zhang Z-M, Warren J, et al. "Electrocardiographic predictors of coronary heart disease and sudden cardiac deaths in men and women free from cardiovascular disease in the Atherosclerosis Risk in Communities study." J Am Heart Assoc. 2013;2(3):e000061.
O'Neal WT, Wang YGrace, Wu H-T, et al. "Electrocardiographic J Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2016;118(6):811-815.
Shahar E, Folsom AR, Jackson R. "The effect of nonresponse on prevalence estimates for a referent population: insights from a population-based cohort study. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Ann Epidemiol. 1996;6(6):498-506.
Pollitt RA, Kaufman JS, Rose KM, Diez-Roux AV, Zeng D, Heiss G. "Early-life and adult socioeconomic status and inflammatory risk markers in adulthood." Eur J Epidemiol. 2007;22(1):55-66.