ARIC Publications
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Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
"New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders." Nat Hum Behav. 2019;3(9):950-961.
"Prevalence of Chronic Disease in Laboratory-Confirmed COVID-19 Cases and U.S. Adults (2017-2018)." Diabetes Care. 2020;43(10):e127-e128.
"Whole-Exome Sequencing in Familial Parkinson Disease." JAMA Neurol. 2016;73(1):68-75.
"Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries." PLoS One. 2018;13(6):e0198166.
"Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study." BMC Med Genet. 2013;14:98.
"Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study." BMC Med Genet. 2013;14:6.
"Cardiovascular Disease Risk Among Cancer Survivors: The Atherosclerosis Risk In Communities (ARIC) Study." J Am Coll Cardiol. 2022;80(1):22-32.
"Implications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies." Am J Clin Nutr. 1991;53(6 Suppl):1604S-1611S.
"Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based study." Arterioscler Thromb Vasc Biol. 2002;22(6):1018-22.
"Prospective associations of fasting insulin, body fat distribution, and diabetes with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Diabetes Care. 1999;22(7):1077-83.
"Is fasting insulin concentration inversely associated with rate of weight gain? Contrasting findings from the CARDIA and ARIC study cohorts." Int J Obes Relat Metab Disord. 1998;22(1):48-54.
"Neighborhood socioeconomic disparities and 1-year case fatality after incident myocardial infarction: the Atherosclerosis Risk in Communities (ARIC) Community Surveillance (1992-2002)." Am Heart J. 2013;165(1):102-7.
"Variation in rates of fatal coronary heart disease by neighborhood socioeconomic status: the atherosclerosis risk in communities surveillance (1992-2002)." Ann Epidemiol. 2011;21(8):580-8.
"Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7." Stroke. 2014;45(11):3194-9.
"Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events." Eur J Prev Cardiol. 2014;21(3):310-20.
"Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort." JAMA Cardiol. 2016;1(1):15-25.
"Discovery and fine mapping of serum protein loci through transethnic meta-analysis." Am J Hum Genet. 2012;91(4):744-53.
" "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.
"Association of Changes in Cardiovascular Health Metrics and Risk of Subsequent Cardiovascular Disease and Mortality." J Am Heart Assoc. 2020;9(19):e017458.
""Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017." Lancet. 2018;392(10159):1789-1858.
Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals." Circ Res. 2019;125(8):773-782.
"Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey: 1985-2015 vs The Atherosclerosis Risk in Communities Study Cohort: 1987-2015." Ethn Dis. 2019;29(1):47-52.
"Novel associations between blood DNA methylation and body mass index in middle-aged and older adults." Int J Obes (Lond). 2018;42(4):887-896.
"Association of apolipoprotein A1 and B with kidney function and chronic kidney disease in two multiethnic population samples." Nephrol Dial Transplant. 2012;27(7):2839-47.
"Trends in severity of hospitalized myocardial infarction: the atherosclerosis risk in communities (ARIC) study, 1987-1994." Am Heart J. 2000;139(5):874-80.
"Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation." Environ Int. 2019;132:104723.
"Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
"Fine Mapping and Identification of BMI Loci in African Americans." Am J Hum Genet. 2013;93(4):661-71.
"Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes." Nat Commun. 2021;12(1):3505.
"Age- and sex-dependent upper reference limits for the high-sensitivity cardiac troponin T assay." J Am Coll Cardiol. 2014;63(14):1441-8.
"Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort." JAMA Neurol. 2017;74(10):1246-1254.
"Does snoring predict sleepiness independently of apnea and hypopnea frequency?" Am J Respir Crit Care Med. 2000;162(4 Pt 1):1512-7.
"The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study." Diabetes. 2013;62(5):1763-7.
"Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate." N Engl J Med. 2016;374(5):411-21.
"A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):591-601.
"Genetic invalidation of Lp-PLA as a therapeutic target: Large-scale study of five functional Lp-PLA-lowering alleles." Eur J Prev Cardiol. 2017;24(5):492-504.
"Cardiovascular Risk Factors Associated With Venous Thromboembolism." JAMA Cardiol. 2019;4(2):163-173.
"Gene-environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities study." Int J Obes (Lond). 2007;31(6):919-26.
"Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium." Circ Cardiovasc Genet. 2014;7(3):321-331.
"CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis." J Clin Invest. 2018;128(3):1106-1124.
" "Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies." Lancet Diabetes Endocrinol. 2017;5(12):965-974.
"Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu." Circ Cardiovasc Genet. 2013;6(2):171-83.
"Dietary Protein Sources and Risk for Incident Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study." J Ren Nutr. 2017;27(4):233-242.
"Molecular genetic contributions to self-rated health." Int J Epidemiol. 2017;46(3):994-1009.
"Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers." Arch Gen Psychiatry. 2012;69(8):854-60.
"Metabolites Associated with Coffee Consumption and Incident Chronic Kidney Disease." Clin J Am Soc Nephrol. 2021;16(11):1620-1629.
"Reproductive aging-associated common genetic variants and the risk of breast cancer." Breast Cancer Res. 2012;14(2):R54.
"Novel genetic loci associated with hippocampal volume." Nat Commun. 2017;8:13624.
"Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nat Genet. 2017;49(3):426-432.
"White Matter Lesion Progression: Genome-Wide Search for Genetic Influences." Stroke. 2015;46(11):3048-57.
"Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults." Nat Commun. 2020;11(1):4796.
"Association of cigarette smoking with albuminuria in the United States: the third National Health and Nutrition Examination Survey." Ren Fail. 2007;29(2):133-42.
"Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index." PLoS Genet. 2014;10(7):e1004508.
"Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of U.S. adults." Environ Res. 2022;212(Pt C):113360.
"Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
"Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data." BMJ. 2014;349:g4164.
"Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations." J Clin Endocrinol Metab. 2018;103(4):1380-1392.
"Overweight and obesity in young and middle age and early retirement: the ARIC study." Obesity (Silver Spring). 2009;17(1):143-9.
"Dairy, fruit, and vegetable intakes and functional limitations and disability in a biracial cohort: the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2005;81(2):515-22.
"Role of weight history on functional limitations and disability in late adulthood: the ARIC study." Obes Res. 2005;13(10):1793-802.
"Polysomnography performed in the unattended home versus the attended laboratory setting--Sleep Heart Health Study methodology." Sleep. 2004;27(3):536-40.
"A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans." J Cardiovasc Electrophysiol. 2014;25(11):1150-7.
"Genome-wide association study of lung function decline in adults with and without asthma." J Allergy Clin Immunol. 2012;129(5):1218-28.
"Filtration Markers as Predictors of ESRD and Mortality: Individual Participant Data Meta-Analysis." Clin J Am Soc Nephrol. 2017;12(1):69-78.
"Lack of association between ferritin level and measures of LDL oxidation: the ARIC study. Atherosclerosis Risk in Communities." Atherosclerosis. 1998;139(1):189-95.
" "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Diabetes Mellitus, and Hypertension With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):602-12.
"Novel Genetic Loci Associated With Retinal Microvascular Diameter." Circ Cardiovasc Genet. 2016;9(1):45-54.
"Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium." Hum Mol Genet. 2017;26(11):2156-2163.
"A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
"Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project." Blood. 2013;122(4):590-7.
"Electrophysiological ventricular substrate of stroke: a prospective cohort study in the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open. 2021;11(9):e048542.
"Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies." Gastroenterology. 2016;151(2):351-363.e28.
"Plasma lactate and diabetes risk in 8045 participants of the atherosclerosis risk in communities study." Ann Epidemiol. 2013;23(12):791-796.e4.
" "A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction." J Clin Endocrinol Metab. 2021;106(2):372-387.
"Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
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