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ARIC Publications

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Fesinmeyer MD, North KE, Lim U, et al. "Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study." BMC Med Genet. 2013;14:6.
Folsom AR, Burke GL, Byers CL, et al. "Implications of obesity for cardiovascular disease in blacks: the CARDIA and ARIC studies." Am J Clin Nutr. 1991;53(6 Suppl):1604S-1611S.
Folsom AR, Aleksic N, Wang L, Cushman M, Wu KK, White RH. "Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based study." Arterioscler Thromb Vasc Biol. 2002;22(6):1018-22.
Folsom AR, Rasmussen ML, Chambless LE, et al. "Prospective associations of fasting insulin, body fat distribution, and diabetes with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Diabetes Care. 1999;22(7):1077-83.
Folsom AR, Vitelli LL, Lewis CE, Schreiner PJ, Watson RL, Wagenknecht LE. "Is fasting insulin concentration inversely associated with rate of weight gain? Contrasting findings from the CARDIA and ARIC study cohorts." Int J Obes Relat Metab Disord. 1998;22(1):48-54.
Foraker RE, Rose KM, Kucharska-Newton AM, Ni H, Suchindran CM, Whitsel EA. "Variation in rates of fatal coronary heart disease by neighborhood socioeconomic status: the atherosclerosis risk in communities surveillance (1992-2002)." Ann Epidemiol. 2011;21(8):580-8.
Foraker RE, Patel MD, Whitsel EA, Suchindran CM, Heiss G. "Neighborhood socioeconomic disparities and 1-year case fatality after incident myocardial infarction: the Atherosclerosis Risk in Communities (ARIC) Community Surveillance (1992-2002)." Am Heart J. 2013;165(1):102-7.
Foroud T, Lai D, Koller D, et al. "Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7." Stroke. 2014;45(11):3194-9.
Fowkes FGR, Murray GD, Butcher I, et al. "Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events." Eur J Prev Cardiol. 2014;21(3):310-20.
Fox ER, Samdarshi TE, Musani SK, et al. "Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort." JAMA Cardiol. 2016;1(1):15-25.
Franceschini N, van Rooij FJA, Prins BP, et al. "Discovery and fine mapping of serum protein loci through transethnic meta-analysis." Am J Hum Genet. 2012;91(4):744-53.
Franceschini N, North KE, Arnett D, et al. "The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study." Am J Hypertens. 2009;22(5):552-8.
Ganesh SK, Tragante V, Guo W, et al. "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.
Gaye B, Tajeu GS, Vasan RS, et al. "Association of Changes in Cardiovascular Health Metrics and Risk of Subsequent Cardiovascular Disease and Mortality." J Am Heart Assoc. 2020;9(19):e017458.
"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017." Lancet. 2018;392(10159):1789-1858.
Georgakis MK, Malik R, Björkbacka H, et al. "Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals." Circ Res. 2019;125(8):773-782.
George KM, Folsom AR, Steffen LM, Wagenknecht LE. "Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey: 1985-2015 vs The Atherosclerosis Risk in Communities Study Cohort: 1987-2015." Ethn Dis. 2019;29(1):47-52.
Geurts YM, Dugué P-A, Joo JE, et al. "Novel associations between blood DNA methylation and body mass index in middle-aged and older adults." Int J Obes (Lond). 2018;42(4):887-896.
Goek O-N, Köttgen A, Hoogeveen RC, Ballantyne CM, Coresh JJ. "Association of apolipoprotein A1 and B with kidney function and chronic kidney disease in two multiethnic population samples." Nephrol Dial Transplant. 2012;27(7):2839-47.
Goff DC, Howard G, Wang CH, et al. "Trends in severity of hospitalized myocardial infarction: the atherosclerosis risk in communities (ARIC) study, 1987-1994." Am Heart J. 2000;139(5):874-80.
Gondalia R, Holliday KM, Baldassari A, et al. "Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
Gondalia R, Baldassari A, Holliday KM, et al. "Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation." Environ Int. 2019;132:104723.
Gong J, Schumacher F, Lim U, et al. "Fine Mapping and Identification of BMI Loci in African Americans." Am J Hum Genet. 2013;93(4):661-71.
Goodrich JK, Singer-Berk M, Son R, et al. "Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes." Nat Commun. 2021;12(1):3505.
M Gore O, Seliger SL, Defilippi CR, et al. "Age- and sex-dependent upper reference limits for the high-sensitivity cardiac troponin T assay." J Am Coll Cardiol. 2014;63(14):1441-8.
Gottesman RF, Albert MS, Alonso A, et al. "Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort." JAMA Neurol. 2017;74(10):1246-1254.
Gottlieb DJ, Yao Q, Redline S, Ali T, Mahowald MW. "Does snoring predict sleepiness independently of apnea and hypopnea frequency?" Am J Respir Crit Care Med. 2000;162(4 Pt 1):1512-7.
Graff M, Gordon-Larsen P, Lim U, et al. "The influence of obesity-related single nucleotide polymorphisms on BMI across the life course: the PAGE study." Diabetes. 2013;62(5):1763-7.
Grams ME, Sang Y, Levey AS, et al. "Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate." N Engl J Med. 2016;374(5):411-21.
Grams ME, Sang Y, Ballew SH, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):591-601.
Gregson JM, Freitag DF, Surendran P, et al. "Genetic invalidation of Lp-PLA as a therapeutic target: Large-scale study of five functional Lp-PLA-lowering alleles." Eur J Prev Cardiol. 2017;24(5):492-504.
Gregson J, Kaptoge S, Bolton T, et al. "Cardiovascular Risk Factors Associated With Venous Thromboembolism." JAMA Cardiol. 2019;4(2):163-173.
Grove ML, Morrison A, Folsom AR, Boerwinkle E, Hoelscher DM, Bray MS. "Gene-environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities study." Int J Obes (Lond). 2007;31(6):919-26.
Guan W, Steffen BT, Lemaitre RN, et al. "Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium." Circ Cardiovasc Genet. 2014;7(3):321-331.
Guo L, Akahori H, Harari E, et al. "CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis." J Clin Invest. 2018;128(3):1106-1124.
Gurka MJ, Golden SH, Musani SK, et al. "Independent associations between a metabolic syndrome severity score and future diabetes by sex and race: the Atherosclerosis Risk In Communities Study and Jackson Heart Study." Diabetologia. 2017;60(7):1261-1270.
H Y Wu J, Lemaitre RN, Manichaikul A, et al. "Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu." Circ Cardiovasc Genet. 2013;6(2):171-83.
H Y Wu J, Marklund M, Imamura F, et al. "Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies." Lancet Diabetes Endocrinol. 2017;5(12):965-974.
Haring B, Selvin E, Liang M, et al. "Dietary Protein Sources and Risk for Incident Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study." J Ren Nutr. 2017;27(4):233-242.
Harris SE, Hagenaars SP, Davies G, et al. "Molecular genetic contributions to self-rated health." Int J Epidemiol. 2017;46(3):994-1009.
Hartz SM, Short SE, Saccone NL, et al. "Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers." Arch Gen Psychiatry. 2012;69(8):854-60.
He C, Chasman DI, Dreyfus J, et al. "Reproductive aging-associated common genetic variants and the risk of breast cancer." Breast Cancer Res. 2012;14(2):R54.
Hibar DP, Adams HHH, Jahanshad N, et al. "Novel genetic loci associated with hippocampal volume." Nat Commun. 2017;8:13624.
Hobbs BD, de Jong K, Lamontagne M, et al. "Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nat Genet. 2017;49(3):426-432.
Hofer E, Cavalieri M, Bis JC, et al. "White Matter Lesion Progression: Genome-Wide Search for Genetic Influences." Stroke. 2015;46(11):3048-57.
Hofer E, Roshchupkin GV, Adams HHH, et al. "Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults." Nat Commun. 2020;11(1):4796.
Hogan SL, Vupputuri S, Guo X, et al. "Association of cigarette smoking with albuminuria in the United States: the third National Health and Nutrition Examination Survey." Ren Fail. 2007;29(2):133-42.
Hoggart CJ, Venturini G, Mangino M, et al. "Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index." PLoS Genet. 2014;10(7):e1004508.
Holmes MV, Lange LA, Palmer T, et al. "Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
Holmes MV, Dale CE, Zuccolo L, et al. "Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data." BMJ. 2014;349:g4164.
Hong J, Hatchell KE, Bradfield JP, et al. "Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations." J Clin Endocrinol Metab. 2018;103(4):1380-1392.
Houston DK, Cai J, Stevens J. "Overweight and obesity in young and middle age and early retirement: the ARIC study." Obesity (Silver Spring). 2009;17(1):143-9.
Houston DK, Stevens J, Cai J, Haines PS. "Dairy, fruit, and vegetable intakes and functional limitations and disability in a biracial cohort: the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2005;81(2):515-22.
Houston DK, Stevens J, Cai J, Morey MC. "Role of weight history on functional limitations and disability in late adulthood: the ARIC study." Obes Res. 2005;13(10):1793-802.
Iber C, Redline S, Kaplan Gilpin AM, et al. "Polysomnography performed in the unattended home versus the attended laboratory setting--Sleep Heart Health Study methodology." Sleep. 2004;27(3):536-40.
Ilkhanoff L, Arking DE, Lemaitre RN, et al. "A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans." J Cardiovasc Electrophysiol. 2014;25(11):1150-7.
Imboden M, Bouzigon E, Curjuric I, et al. "Genome-wide association study of lung function decline in adults with and without asthma." J Allergy Clin Immunol. 2012;129(5):1218-28.
Inker LA, Coresh JJ, Sang Y, et al. "Filtration Markers as Predictors of ESRD and Mortality: Individual Participant Data Meta-Analysis." Clin J Am Soc Nephrol. 2017;12(1):69-78.
Iribarren C, Sempos CT, Eckfeldt JH, Folsom AR. "Lack of association between ferritin level and measures of LDL oxidation: the ARIC study. Atherosclerosis Risk in Communities." Atherosclerosis. 1998;139(1):189-95.
James MT, Grams ME, Woodward M, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Diabetes Mellitus, and Hypertension With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):602-12.
Jensen MK, Jensen RA, Mukamal KJ, et al. "Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium." Hum Mol Genet. 2017;26(11):2156-2163.
Jensen RA, Sim X, Smith A V, et al. "Novel Genetic Loci Associated With Retinal Microvascular Diameter." Circ Cardiovasc Genet. 2016;9(1):45-54.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Johnsen JM, Auer PL, Morrison AC, et al. "Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project." Blood. 2013;122(4):590-7.
Johnson JA, Haq KT, Lutz KJ, et al. "Electrophysiological ventricular substrate of stroke: a prospective cohort study in the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open. 2021;11(9):e048542.
Joshi AD, Andersson C, Buch S, et al. "Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies." Gastroenterology. 2016;151(2):351-363.e28.
Juraschek SP, Selvin E, Miller ER, Brancati FL. "Plasma lactate and diabetes risk in 8045 participants of the atherosclerosis risk in communities study." Ann Epidemiol. 2013;23(12):791-796.e4.
Justice AE, Winkler TW, Feitosa MF, et al. "Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits." Nat Commun. 2017;8:14977.
Kahali B, Chen Y, Feitosa MF, et al. "A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction." J Clin Endocrinol Metab. 2021;106(2):372-387.
Kan H, Stevens J, Heiss G, Rose KM, London SJ. "Dietary fiber, lung function, and chronic obstructive pulmonary disease in the atherosclerosis risk in communities study." Am J Epidemiol. 2008;167(5):570-8.
Kan M, Auer PL, Wang GT, et al. "Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
Kan H, Heiss G, Rose KM, Whitsel EA, Lurmann F, London SJ. "Prospective analysis of traffic exposure as a risk factor for incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study." Environ Health Perspect. 2008;116(11):1463-8.
Kao WH, Folsom AR, Nieto FJ, Mo JP, Watson RL, Brancati FL. "Serum and dietary magnesium and the risk for type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study." Arch Intern Med. 1999;159(18):2151-9.
Katz EG, Stevens J, Truesdale KP, Cai J, North KE. "Associations of body mass index with incident hypertension in American white, American black and Chinese Asian adults in early and middle adulthood: the Coronary Artery Risk Development in Young Adults (CARDIA) study, the Atherosclerosis Risk in Communiti." Asia Pac J Clin Nutr. 2013;22(4):626-34.
Keaton JM, Gao C, Guan M, et al. "Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans." Genet Epidemiol. 2018;42(6):559-570.
Keaton JM, Hellwege JN, C Y Ng M, et al. "Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans." PLoS One. 2016;11(7):e0159977.
Kessler MD, Loesch DP, Perry JA, et al. "De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population." Proc Natl Acad Sci U S A. 2020;117(5):2560-2569.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
Klimentidis YC, Raichlen DA, Bea J, et al. "Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE." Int J Obes (Lond). 2018;42(6):1161-1176.
Klos K, Shimmin L, Ballantyne C, et al. "APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels." Hum Mol Genet. 2008;17(13):2039-46.