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ARIC Publications

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Journal Article
Assimes TL, Knowles JW, Priest JR, et al. "Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease." Hum Genet. 2008;123(4):399-408.
Ilkhanoff L, Arking DE, Lemaitre RN, et al. "A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans." J Cardiovasc Electrophysiol. 2014;25(11):1150-7.
Soranzo N, Sanna S, Wheeler E, et al. "Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways." Diabetes. 2010;59(12):3229-39.
Ellinor PT, Lunetta KL, Glazer NL, et al. "Common variants in KCNN3 are associated with lone atrial fibrillation." Nat Genet. 2010;42(3):240-4.
White AD, Folsom AR, Chambless LE, et al. "Community surveillance of coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) Study: methods and initial two years' experience." J Clin Epidemiol. 1996;49(2):223-33.
Saito I, Folsom AR, Aono H, Ozawa H, Ikebe T, Yamashita T. "Comparison of fatal coronary heart disease occurrence based on population surveys in Japan and the USA." Int J Epidemiol. 2000;29(5):837-44.
Rosamond W, Broda G, Kawalec E, et al. "Comparison of medical care and survival of hospitalized patients with acute myocardial infarction in Poland and the United States." Am J Cardiol. 1999;83(8):1180-5.
Sikdar S, Joehanes R, Joubert BR, et al. "Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking." Epigenomics. 2019;11(13):1487-1500.
Yu B, Zanetti KA, Temprosa M, et al. "The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies." Am J Epidemiol. 2019;188(6):991-1012.
Rosamond WD, Folsom AR, Chambless LE, Wang CH. "Coronary heart disease trends in four United States communities. The Atherosclerosis Risk in Communities (ARIC) study 1987-1996." Int J Epidemiol. 2001;30 Suppl 1:S17-22.
Kaptoge S, Di Angelantonio E, Pennells L, et al. "C-reactive protein, fibrinogen, and cardiovascular disease prediction." N Engl J Med. 2012;367(14):1310-20.
Pollitt RA, Kaufman JS, Rose KM, Diez-Roux AV, Zeng D, Heiss G. "Cumulative life course and adult socioeconomic status and markers of inflammation in adulthood." J Epidemiol Community Health. 2008;62(6):484-91.
"Dairy Consumption and Body Mass Index Among Adults: Mendelian Randomization Analysis of 184802 Individuals from 25 Studies." Clin Chem. 2018;64(1):183-191.
Houston DK, Stevens J, Cai J, Haines PS. "Dairy, fruit, and vegetable intakes and functional limitations and disability in a biracial cohort: the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2005;81(2):515-22.
Kessler MD, Loesch DP, Perry JA, et al. "De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population." Proc Natl Acad Sci U S A. 2020;117(5):2560-2569.
Coresh JJ, Turin TChowdhury, Matsushita K, et al. "Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality." JAMA. 2014;311(24):2518-2531.
Myerson M, Coady S, Taylor H, Rosamond WD, Goff DC. "Declining severity of myocardial infarction from 1987 to 2002: the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2009;119(4):503-14.
Wood AR, Esko T, Yang J, et al. "Defining the role of common variation in the genomic and biological architecture of adult human height." Nat Genet. 2014;46(11):1173-86.
Jensen MK, Jensen RA, Mukamal KJ, et al. "Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium." Hum Mol Genet. 2017;26(11):2156-2163.
Rubin J, Matsushita K, Lazo M, et al. "Determinants of minimal elevation in high-sensitivity cardiac troponin T in the general population." Clin Biochem. 2016;49(9):657-662.
Goodrich JK, Singer-Berk M, Son R, et al. "Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes." Nat Commun. 2021;12(1):3505.
Butler KR, Penman AD, Minor DS. "Determinants of pulse pressure and annual rates of change in the Atherosclerosis Risk in Communities study." J Hypertens. 2015;33(12):2463-70.
Deo R, Norby FL, Katz R, et al. "Development and Validation of a Sudden Cardiac Death Prediction Model for the General Population." Circulation. 2016;134(11):806-16.
Fowkes FGR, Murray GD, Butcher I, et al. "Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events." Eur J Prev Cardiol. 2014;21(3):310-20.
Fox ER, Samdarshi TE, Musani SK, et al. "Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort." JAMA Cardiol. 2016;1(1):15-25.
Schneider ALC, Kalyani RR, Golden S, et al. "Diabetes and Prediabetes and Risk of Hospitalization: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):772-9.
Echouffo-Tcheugui JB, Daya N, Ndumele CE, et al. "Diabetes, GDF-15 and incident heart failure: the atherosclerosis risk in communities study." Diabetologia. 2022;65(6):955-963.
Rebholz CM, Coresh JJ, Grams ME, Steffen LM, Anderson CAM, Appel LJ. "Dietary Acid Load and Incident Chronic Kidney Disease: Results from the ARIC Study." Am J Nephrol. 2015;42(6):427-35.
Stevens J, Ahn K, Houston D, Steffan L, Couper D. "Dietary fiber intake and glycemic index and incidence of diabetes in African-American and white adults: the ARIC study." Diabetes Care. 2002;25(10):1715-21.
Kan H, Stevens J, Heiss G, Rose KM, London SJ. "Dietary fiber, lung function, and chronic obstructive pulmonary disease in the atherosclerosis risk in communities study." Am J Epidemiol. 2008;167(5):570-8.
Haring B, Selvin E, Liang M, et al. "Dietary Protein Sources and Risk for Incident Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study." J Ren Nutr. 2017;27(4):233-242.
George KM, Folsom AR, Steffen LM, Wagenknecht LE. "Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey: 1985-2015 vs The Atherosclerosis Risk in Communities Study Cohort: 1987-2015." Ethn Dis. 2019;29(1):47-52.
Islek D, Alonso A, Rosamond W, et al. "Differences in incident and recurrent myocardial infarction among White and Black individuals aged 35 to 84: Findings from the ARIC community surveillance study." Am Heart J. 2022;253:67-75.
Franceschini N, van Rooij FJA, Prins BP, et al. "Discovery and fine mapping of serum protein loci through transethnic meta-analysis." Am J Hum Genet. 2012;91(4):744-53.
van den Berg ME, Warren HR, Cabrera CP, et al. "Discovery of novel heart rate-associated loci using the Exome Chip." Hum Mol Genet. 2017;26(12):2346-2363.
Liu C, Marioni RE, Hedman ÅK, et al. "A DNA methylation biomarker of alcohol consumption." Mol Psychiatry. 2018;23(2):422-433.
Gottlieb DJ, Yao Q, Redline S, Ali T, Mahowald MW. "Does snoring predict sleepiness independently of apnea and hypopnea frequency?" Am J Respir Crit Care Med. 2000;162(4 Pt 1):1512-7.
Wei GS, Coady SA, Reis JP, et al. "Duration and Degree of Weight Gain and Incident Diabetes in Younger Versus Middle-Aged Black and White Adults: ARIC, CARDIA, and the Framingham Heart Study." Diabetes Care. 2015;38(11):2042-9.
Arora S, Matsushita K, Qamar A, R Stacey B. "Early versus late percutaneous revascularization in patients hospitalized with non ST-segment elevation myocardial infarction: The atherosclerosis risk in communities surveillance study." Catheter Cardiovasc Interv. 2018;91(2):253-259.
Fesinmeyer MD, North KE, Lim U, et al. "Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study." BMC Med Genet. 2013;14:6.
Soliman EZ, Prineas RJ, Case DL, et al. "Electrocardiographic and clinical predictors separating atherosclerotic sudden cardiac death from incident coronary heart disease." Heart. 2011;97(19):1597-601.
Johnson JA, Haq KT, Lutz KJ, et al. "Electrophysiological ventricular substrate of stroke: a prospective cohort study in the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open. 2021;11(9):e048542.
Arbes SJ, Agústsdóttir H, Slade GD. "Environmental tobacco smoke and periodontal disease in the United States." Am J Public Health. 2001;91(2):253-7.
Syme C, Shin J, Richer L, Gaudet D, Fornage M, Paus T. "Epigenetic Loci of Blood Pressure." Circ Genom Precis Med. 2019;12(1):e002341.
Wang X, Pan Y, Zhu H, et al. "An epigenome-wide study of obesity in African American youth and young adults: novel findings, replication in neutrophils, and relationship with gene expression." Clin Epigenetics. 2018;10:3.
Matsushita K, Coresh JJ, Sang Y, et al. "Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data." Lancet Diabetes Endocrinol. 2015;3(7):514-25.
Spracklen CN, Karaderi T, Yaghootkar H, et al. "Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.
Riveros-Mckay F, Roberts D, Di Angelantonio E, et al. "An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript." Diabetes. 2022;71(2):359-364.
Divaris K, Monda KL, North KE, et al. "Exploring the genetic basis of chronic periodontitis: a genome-wide association study." Hum Mol Genet. 2013;22(11):2312-24.
Knowles JW, Assimes TL, Boerwinkle E, et al. "Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD." BMC Med Genet. 2008;9:23.
Pereira MA, Schreiner PJ, Pankow JS, et al. "The Family Risk Score for coronary heart disease: associations with lipids, lipoproteins, and body habitus in a middle-aged bi-racial cohort: The ARIC study." Ann Epidemiol. 2000;10(4):239-45.
Folsom AR, Vitelli LL, Lewis CE, Schreiner PJ, Watson RL, Wagenknecht LE. "Is fasting insulin concentration inversely associated with rate of weight gain? Contrasting findings from the CARDIA and ARIC study cohorts." Int J Obes Relat Metab Disord. 1998;22(1):48-54.
Beck TF, Campeau PM, Jhangiani SN, et al. "FBN1 contributing to familial congenital diaphragmatic hernia." Am J Med Genet A. 2015;167A(4):831-6.
Arora S, Stouffer GA, Kucharska-Newton AMaria, et al. "Fifteen-Year Trends in Management and Outcomes of Non-ST-Segment-Elevation Myocardial Infarction Among Black and White Patients: The ARIC Community Surveillance Study, 2000-2014." J Am Heart Assoc. 2018;7(19):e010203.
Inker LA, Coresh JJ, Sang Y, et al. "Filtration Markers as Predictors of ESRD and Mortality: Individual Participant Data Meta-Analysis." Clin J Am Soc Nephrol. 2017;12(1):69-78.
Gong J, Schumacher F, Lim U, et al. "Fine Mapping and Identification of BMI Loci in African Americans." Am J Hum Genet. 2013;93(4):661-71.
Boerwinkle E. "Following-up genome-wide association study signals: lessons learned from Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):332-4.
Joshi AD, Andersson C, Buch S, et al. "Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies." Gastroenterology. 2016;151(2):351-363.e28.
Watkins S, Thiemann D, Coresh J, Powe N, Folsom AR, Rosamond W. "Fourteen-year (1987 to 2000) trends in the attack rates of, therapy for, and mortality from non-ST-elevation acute coronary syndromes in four United States communities." Am J Cardiol. 2005;96(10):1349-55.
Qi Q, Kilpeläinen TO, Downer MK, et al. "FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals." Hum Mol Genet. 2014;23(25):6961-72.
Petty LE, Highland HM, Gamazon ER, et al. "Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample." Hum Mol Genet. 2019;28(7):1212-1224.
Holliday KM, Gondalia R, Baldassari A, et al. "Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of U.S. adults." Environ Res. 2022;212(Pt C):113360.
Weitzman S, Cooper L, Chambless L, et al. "Gender, racial, and geographic differences in the performance of cardiac diagnostic and therapeutic procedures for hospitalized acute myocardial infarction in four states." Am J Cardiol. 1997;79(6):722-6.
Nettleton JA, Follis JL, Ngwa JS, et al. "Gene × dietary pattern interactions in obesity: analysis of up to 68 317 adults of European ancestry." Hum Mol Genet. 2015;24(16):4728-38.
Simino J, Shi G, Bis JC, et al. "Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia." Am J Hum Genet. 2014;95(1):24-38.
Tang W, Cushman M, Green D, et al. "Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans." Am J Hematol. 2015;90(6):534-40.
Yoneyama S, Guo Y, Lanktree MB, et al. "Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations." Hum Mol Genet. 2014;23(9):2498-510.
Grove ML, Morrison A, Folsom AR, Boerwinkle E, Hoelscher DM, Bray MS. "Gene-environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities study." Int J Obes (Lond). 2007;31(6):919-26.
Yoneyama S, Yao J, Guo X, et al. "Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations." Int J Obes (Lond). 2017;41(2):324-331.
Evangelou E, Warren HR, Mosen-Ansorena D, et al. "Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
Satizabal CL, Adams HHH, Hibar DP, et al. "Genetic architecture of subcortical brain structures in 38,851 individuals." Nat Genet. 2019;51(11):1624-1636.
Weng L-C, Tang W, Rich SS, et al. "A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups." Thromb Res. 2014;134(2):462-7.
Arking DE, Pulit SL, Crotti L, et al. "Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization." Nat Genet. 2014;46(8):826-36.
Hofer E, Roshchupkin GV, Adams HHH, et al. "Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults." Nat Commun. 2020;11(1):4796.
Wassel CL, Lamina C, Nambi V, et al. "Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium." Atherosclerosis. 2012;222(1):138-47.
Gregson JM, Freitag DF, Surendran P, et al. "Genetic invalidation of Lp-PLA as a therapeutic target: Large-scale study of five functional Lp-PLA-lowering alleles." Eur J Prev Cardiol. 2017;24(5):492-504.
Sakornsakolpat P, Prokopenko D, Lamontagne M, et al. "Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations." Nat Genet. 2019;51(3):494-505.
Hobbs BD, de Jong K, Lamontagne M, et al. "Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nat Genet. 2017;49(3):426-432.
Lieb W, Jansen H, Loley C, et al. "Genetic predisposition to higher blood pressure increases coronary artery disease risk." Hypertension. 2013;61(5):995-1001.
Robinson-Cohen C, Lutsey PL, Kleber ME, et al. "Genetic Variants Associated with Circulating Parathyroid Hormone." J Am Soc Nephrol. 2017;28(5):1553-1565.