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ARIC Publications

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Journal Article
Shuldiner AR, Nguyen W, Kao WH, et al. "Pro115Gln peroxisome proliferator-activated receptor-gamma and obesity." Diabetes Care. 2000;23(1):126-7.
Toole JF, Chambless LE, Heiss G, Tyroler HA, Paton CC. "Prevalence of stroke and transient ischemic attacks in the Atherosclerosis Risk in Communities (ARIC) study." Ann Epidemiol. 1993;3(5):500-3.
Fang M, Wang D, Tang O, Selvin E. "Prevalence of Chronic Disease in Laboratory-Confirmed COVID-19 Cases and U.S. Adults (2017-2018)." Diabetes Care. 2020;43(10):e127-e128.
Dumitrescu L, Carty CL, Franceschini N, et al. "Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study." Ann Hum Genet. 2013;77(5):416-25.
Iber C, Redline S, Kaplan Gilpin AM, et al. "Polysomnography performed in the unattended home versus the attended laboratory setting--Sleep Heart Health Study methodology." Sleep. 2004;27(3):536-40.
Winkelman JW, Redline S, Baldwin CM, Resnick HE, Newman AB, Gottlieb DJ. "Polysomnographic and health-related quality of life correlates of restless legs syndrome in the Sleep Heart Health Study." Sleep. 2009;32(6):772-8.
Surguchov AP, Page GP, Smith L, Patsch W, Boerwinkle E. "Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia." Arterioscler Thromb Vasc Biol. 1996;16(8):941-7.
White J, Beck CR, Harel T, et al. "POGZ truncating alleles cause syndromic intellectual disability." Genome Med. 2016;8(1):3.
S Park L, Fesinmeyer MD, Timofeeva M, et al. "Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia." J Natl Cancer Inst. 2014;106(4):dju061.
Juraschek SP, Selvin E, Miller ER, Brancati FL. "Plasma lactate and diabetes risk in 8045 participants of the atherosclerosis risk in communities study." Ann Epidemiol. 2013;23(12):791-796.e4.
Seyerle AA, Sitlani CM, Noordam R, et al. "Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology." Pharmacogenomics J. 2018;18(2):215-226.
Morelli T, Moss KL, Preisser JS, Beck JD, Divaris K, Wu D. "Periodontal profile classes predict periodontal disease progression and tooth loss." J Periodontol. 2018;89(2):148-156.
Lutsey PL, Folsom AR, Heckbert SR, Cushman M. "Peak thrombin generation and subsequent venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE) study." J Thromb Haemost. 2009;7(10):1639-48.
Reis JP, Selvin E, Pankow JS, Michos ED, Rebholz CM. "Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Metab. 2016;42(3):162-9.
Houston DK, Cai J, Stevens J. "Overweight and obesity in young and middle age and early retirement: the ARIC study." Obesity (Silver Spring). 2009;17(1):143-9.
Olden M, Teumer A, Bochud M, et al. "Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium." Am J Kidney Dis. 2013;61(6):889-98.
H Y Wu J, Marklund M, Imamura F, et al. "Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39 740 adults from 20 prospective cohort studies." Lancet Diabetes Endocrinol. 2017;5(12):965-974.
Ndumele CE, Matsushita K, Lazo M, et al. "Obesity and Subtypes of Incident Cardiovascular Disease." J Am Heart Assoc. 2016;5(8).
Matsushita K, Sang Y, Chen J, et al. "Novel "Predictor Patch" Method for Adding Predictors Using Estimates From Outside Datasets - A Proof-of-Concept Study Adding Kidney Measures to Cardiovascular Mortality Prediction." Circ J. 2019;83(9):1876-1882.
Blumenthal JB, Andersen RE, Mitchell BD, et al. "Novel neuropeptide Y1 and Y5 receptor gene variants: associations with serum triglyceride and high-density lipoprotein cholesterol levels." Clin Genet. 2002;62(3):196-202.
Butler AM, Yin X, Evans DS, et al. "Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts." Circ Cardiovasc Genet. 2012;5(6):639-46.
Lubitz SA, Lunetta KL, Lin H, et al. "Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese." J Am Coll Cardiol. 2014;63(12):1200-1210.
Jensen RA, Sim X, Smith A V, et al. "Novel Genetic Loci Associated With Retinal Microvascular Diameter." Circ Cardiovasc Genet. 2016;9(1):45-54.
Hibar DP, Adams HHH, Jahanshad N, et al. "Novel genetic loci associated with hippocampal volume." Nat Commun. 2017;8:13624.
Feitosa MF, Kraja AT, Chasman DI, et al. "Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries." PLoS One. 2018;13(6):e0198166.
Smith NL, Chen M-H, Dehghan A, et al. "Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium." Circulation. 2010;121(12):1382-92.
Geurts YM, Dugué P-A, Joo JE, et al. "Novel associations between blood DNA methylation and body mass index in middle-aged and older adults." Int J Obes (Lond). 2018;42(4):887-896.
Hoggart CJ, Venturini G, Mangino M, et al. "Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index." PLoS Genet. 2014;10(7):e1004508.
Chu AY, Coresh J, Arking DE, et al. "NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2010;53(3):510-6.
Kahali B, Chen Y, Feitosa MF, et al. "A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction." J Clin Endocrinol Metab. 2021;106(2):372-387.
Evangelou E, Gao H, Chu C, et al. "New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders." Nat Hum Behav. 2019;3(9):950-961.
van Lenthe FJ, Borrell LN, Costa G, et al. "Neighbourhood unemployment and all cause mortality: a comparison of six countries." J Epidemiol Community Health. 2005;59(3):231-7.
Foraker RE, Patel MD, Whitsel EA, Suchindran CM, Heiss G. "Neighborhood socioeconomic disparities and 1-year case fatality after incident myocardial infarction: the Atherosclerosis Risk in Communities (ARIC) Community Surveillance (1992-2002)." Am Heart J. 2013;165(1):102-7.
Rose KM, Foraker RE, Heiss G, Rosamond WD, Suchindran CM. "Neighborhood socioeconomic and racial disparities in angiography and coronary revascularization: the ARIC surveillance study." Ann Epidemiol. 2012;22(9):623-9.
Rose KM, Suchindran CM, Foraker RE, et al. "Neighborhood disparities in incident hospitalized myocardial infarction in four U.S. communities: the ARIC surveillance study." Ann Epidemiol. 2009;19(12):867-74.
Arking DE, Khera A, Xing C, et al. "Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population." PLoS One. 2009;4(1):e4333.
Sabater-Lleal M, Huang J, Chasman D, et al. "Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease." Circulation. 2013;128(12):1310-24.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
Noordam R, Bos MM, Wang H, et al. "Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration." Nat Commun. 2019;10(1):5121.
Bentley AR, Sung YJ, Brown MR, et al. "Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids." Nat Genet. 2019;51(4):636-648.
de Vries PS, Brown MR, Bentley AR, et al. "Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions." Am J Epidemiol. 2019;188(6):1033-1054.
Kocarnik JM, Pendergrass SA, Carty CL, et al. "Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study." Circ Cardiovasc Genet. 2014;7(2):178-88.
Harris SE, Hagenaars SP, Davies G, et al. "Molecular genetic contributions to self-rated health." Int J Epidemiol. 2017;46(3):994-1009.
Rose KM, Carson AP, Sanford CP, et al. "Migraine and other headaches: associations with Rose angina and coronary heart disease." Neurology. 2004;63(12):2233-9.
Power MC, Tingle JV, Reid RI, et al. "Midlife and Late-Life Vascular Risk Factors and White Matter Microstructural Integrity: The Atherosclerosis Risk in Communities Neurocognitive Study." J Am Heart Assoc. 2017;6(5).
Gondalia R, Baldassari A, Holliday KM, et al. "Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation." Environ Int. 2019;132:104723.
Chamberlain AM, Agarwal SK, Ambrose M, Folsom AR, Soliman EZ, Alonso A. "Metabolic syndrome and incidence of atrial fibrillation among blacks and whites in the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2010;159(5):850-6.
McGeechan K, Liew G, Macaskill P, et al. "Meta-analysis: retinal vessel caliber and risk for coronary heart disease." Ann Intern Med. 2009;151(6):404-13.
James MT, Grams ME, Woodward M, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Diabetes Mellitus, and Hypertension With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):602-12.
Grams ME, Sang Y, Ballew SH, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):591-601.
Bis JC, Kavousi M, Franceschini N, et al. "Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque." Nat Genet. 2011;43(10):940-7.
Marioni RE, McRae AF, Bressler J, et al. "Meta-analysis of epigenome-wide association studies of cognitive abilities." Mol Psychiatry. 2018;23(11):2133-2144.
de Vries PS, Chasman DI, Sabater-Lleal M, et al. "A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration." Hum Mol Genet. 2016;25(2):358-70.
Ellinor PT, Lunetta KL, Albert CM, et al. "Meta-analysis identifies six new susceptibility loci for atrial fibrillation." Nat Genet. 2012;44(6):670-5.
Qayyum R, Snively BM, Ziv E, et al. "A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans." PLoS Genet. 2012;8(3):e1002491.
Xu J, Bartz TM, Chittoor G, et al. "Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function." Br J Nutr. 2018;120(10):1159-1170.
O'Brien EC, Rose KM, Suchindran CM, et al. "Medication, reperfusion therapy and survival in a community-based setting of hospitalised myocardial infarction." Heart. 2013;99(11):767-73.
Mundt KA, Chambless LE, Burnham CB, Heiss G. "Measuring ankle systolic blood pressure: validation of the Dinamap 1846 SX." Angiology. 1992;43(7):555-66.
Matsushita K, Ballew SH, Coresh JJ, et al. "Measures of chronic kidney disease and risk of incident peripheral artery disease: a collaborative meta-analysis of individual participant data." Lancet Diabetes Endocrinol. 2017;5(9):718-728.
Oelsner EC, Balte PP, Bhatt SP, et al. "Lung function decline in former smokers and low-intensity current smokers: a secondary data analysis of the NHLBI Pooled Cohorts Study." Lancet Respir Med. 2020;8(1):34-44.
van der Velde M, Matsushita K, Coresh J, et al. "Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts." Kidney Int. 2011;79(12):1341-52.
Aggarwal V, Schneider ALC. "Low hemoglobin A(1c) in nondiabetic adults: an elevated risk state?" Diabetes Care. 2012;35(10):2055-60.
Lutsey PL, Cushman M, Heckbert SR, Tang W, Folsom AR. "Longer legs are associated with greater risk of incident venous thromboembolism independent of total body height. The Longitudinal Study of Thromboembolism Etiology (LITE)." Thromb Haemost. 2011;106(1):113-20.
Stevens J, Erber E, Truesdale KP, Wang C-H. "Long- and short-term weight change and incident coronary heart disease and ischemic stroke: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2013;178(2):239-48.
Ganesh SK, Tragante V, Guo W, et al. "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.
"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Schneider ALC, Lazo M, Ndumele CE, Pankow JS, Coresh JJ, Clark JM. "Liver enzymes, race, gender and diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study." Diabet Med. 2013;30(8):926-33.
Nambi V, Hoogeveen RC, Chambless L, et al. "Lipoprotein-associated phospholipase A2 and high-sensitivity C-reactive protein improve the stratification of ischemic stroke risk in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2009;40(2):376-81.
Rodriguez S, Gaunt TR, Guo Y, et al. "Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array." Eur J Hum Genet. 2016;24(1):106-12.
Simino J, Kume R, Kraja AT, et al. "Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program." Atherosclerosis. 2014;235(1):84-93.
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
Gondalia R, Holliday KM, Baldassari A, et al. "Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
Day FR, Ruth KS, Thompson DJ, et al. "Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair." Nat Genet. 2015;47(11):1294-1303.
Tang W, Kowgier M, Loth DW, et al. "Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function." PLoS One. 2014;9(7):e100776.
Scott RA, Lagou V, Welch RP, et al. "Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways." Nat Genet. 2012;44(9):991-1005.
Ellis J, Lange EM, Li J, et al. "Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans." Hum Genet. 2014;133(8):985-95.
Iribarren C, Sempos CT, Eckfeldt JH, Folsom AR. "Lack of association between ferritin level and measures of LDL oxidation: the ARIC study. Atherosclerosis Risk in Communities." Atherosclerosis. 1998;139(1):189-95.
Grams ME, Sang Y, Levey AS, et al. "Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate." N Engl J Med. 2016;374(5):411-21.
Rosenthal EA, Ranchalis J, Crosslin DR, et al. "Joint linkage and association analysis with exome sequence data implicates SLC25A40 in hypertriglyceridemia." Am J Hum Genet. 2013;93(6):1035-45.

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