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ARIC Publications

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Yazdani A, Yazdani A, Samiei A. "Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study." J Biomed Inform. 2016;63:337-343.
Yazdani A, Yazdani A, Saniei A. "A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels." Metabolomics. 2016;12:104.
Yazdani A, Yazdani A. "Rare variants analysis using penalization methods for whole genome sequence data." BMC Bioinformatics. 2015;16:405.
Yatsuya H, Folsom AR, Yamagishi K, North KE, Brancati FL, Stevens J. "Race- and sex-specific associations of obesity measures with ischemic stroke incidence in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2010;41(3):417-25.
Yatsuya H, Yamagishi K, North KE, Brancati FL, Stevens J, Folsom AR. "Associations of obesity measures with subtypes of ischemic stroke in the ARIC Study." J Epidemiol. 2010;20(5):347-54.
Yatsuya H, Folsom AR. "Risk of incident cardiovascular disease among users of smokeless tobacco in the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2010;172(5):600-5.
Yatsuya H, Folsom AR, Wong TY, Klein R, Klein BEK, A Sharrett R. "Retinal microvascular abnormalities and risk of lacunar stroke: Atherosclerosis Risk in Communities Study." Stroke. 2010;41(7):1349-55.
Yatsuya H, Folsom AR, Alonso A, Gottesman RF, Rose KM. "Postural changes in blood pressure and incidence of ischemic stroke subtypes: the ARIC study." Hypertension. 2011;57(2):167-73.
Yao L, Folsom AR, Pankow JS, et al. "Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study." J Hypertens. 2016;34(2):196-203.
Yao L, Folsom AR, Alonso A, et al. "Association of carotid atherosclerosis and stiffness with abdominal aortic aneurysm: The atherosclerosis risk in communities (ARIC) study." Atherosclerosis. 2018;270:110-116.
Yano Y, Griswold M, Wang W, et al. "Long-Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study." J Am Heart Assoc. 2018;7(15):e009578.
Yang EY, Chambless L, A Sharrett R, et al. "Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2012;43(1):103-8.
Yang EY, Nambi V, Tang Z, et al. "Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study." J Am Coll Cardiol. 2009;54(25):2388-95.
Yang J, Loos RJF, Powell JE, et al. "FTO genotype is associated with phenotypic variability of body mass index." Nature. 2012;490(7419):267-72.
Yang C, Kwak L, Ballew SH, et al. "Kidney function, bone-mineral metabolism markers, and future risk of peripheral artery disease." Atherosclerosis. 2017;267:167-174.
Yang C, Kwak L, Ballew SH, et al. "Retinal microvascular findings and risk of incident peripheral artery disease: An analysis from the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2020;294:62-71.
Yan Y, Klein R, Heiss G, et al. "The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study." BMC Endocr Disord. 2010;10:9.
Yan Y, North KE, Ballantyne CM, et al. "Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: the Atherosclerosis Risk in Communities study." Diabetes. 2009;58(1):285-9.
Yamagishi K, Cushman M, Heckbert SR, Tsai MY, Folsom AR. "Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study." Br J Haematol. 2009;145(2):221-6.
Yamagishi K, Folsom AR. "Plasma fatty acid composition and incident ischemic stroke in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Cerebrovasc Dis. 2013;36(1):38-46.
Yamagishi K, Aleksic N, Hannan PJ, Folsom AR. "Coagulation factors II, V, IX, X, XI, and XII, plasminogen, and alpha-2 antiplasmin and risk of coronary heart disease." J Atheroscler Thromb. 2010;17(4):402-9.
Yamagishi K, Folsom AR, Rosamond WD, Boerwinkle E. "A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study." Eur Heart J. 2009;30(10):1222-8.
Yamagishi K, Nettleton JA, Folsom AR. "Plasma fatty acid composition and incident heart failure in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2008;156(5):965-74.
Yaghootkar H, Scott RA, White CC, et al. "Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes." Diabetes. 2014;63(12):4369-77.
Yaghootkar H, Lamina C, Scott RA, et al. "Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes." Diabetes. 2013;62(10):3589-98.
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Xu H, Schwander K, Brown MR, et al. "Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions." Eur J Hum Genet. 2021;29(5):839-850.
Xu Z, Steffen LM, Selvin E. "Diet quality, change in diet quality and risk of incident CVD and diabetes." Public Health Nutr. 2020;23(2):329-338.
Xu H, Zhang H, Yang W, et al. "Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children." Nat Commun. 2015;6:7553.
Xu J, Bartz TM, Chittoor G, et al. "Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function." Br J Nutr. 2018;120(10):1159-1170.
Xu J, Liu G, Hegde SM, et al. "Physical Activity-Related Metabolites Are Associated with Mortality: Findings from the Atherosclerosis Risk in Communities (ARIC) Study." Metabolites. 2021;11(1).
Xu J, Gaddis NC, Bartz TM, et al. "Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association." Am J Respir Crit Care Med. 2019;199(5):631-642.
Xing C, Dupuis J. "Performance of statistical methods on CHARGE targeted sequencing data." BMC Genet. 2014;15:104.
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Wyss AB, Sofer T, Lee MKyeong, et al. "Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function." Nat Commun. 2018;9(1):2976.
Wuttke M, Li Y, Li M, et al. "A catalog of genetic loci associated with kidney function from analyses of a million individuals." Nat Genet. 2019;51(6):957-972.
Wu C, Zhang K, Odden MC, et al. "Subclinical Vascular Disease Burden and Premature Mortality Among Middle-aged Adults: the Atherosclerosis Risk in Communities Study." J Gen Intern Med. 2021.
Wu B. "Fast and Accurate Genome-Wide Association Test of Multiple Quantitative Traits." Comput Math Methods Med. 2018;2018:2564531.
Wu B. "Genome-wide association test of multiple continuous traits using imputed SNPs." Stat Interface. 2017;10(3):379-386.
Wu KK, Aleksic N, Ahn C, Boerwinkle E, Folsom AR, Juneja H. "Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease." Circulation. 2001;103(10):1386-9.
Wu KK, Aleksic N, Ballantyne CM, Ahn C, Juneja H, Boerwinkle E. "Interaction between soluble thrombomodulin and intercellular adhesion molecule-1 in predicting risk of coronary heart disease." Circulation. 2003;107(13):1729-32.
Wu B, Guan W. "On Efficient and Accurate Calculation of Significance P-Values for Sequence Kernel Association Testing of Variant Set." Ann Hum Genet. 2016;80(2):123-35.
Wu Y, Waite LL, Jackson AU, et al. "Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained." PLoS Genet. 2013;9(3):e1003379.
Wu A, Coresh JJ, Selvin E, et al. "Lower Extremity Peripheral Artery Disease and Quality of Life Among Older Individuals in the Community." J Am Heart Assoc. 2017;6(1).
Wu KK, Folsom AR, Heiss G, Davis CE, Conlan MG, Barnes R. "Association of coagulation factors and inhibitors with carotid artery atherosclerosis. Early results of the Atherosclerosis Risk in Communities (ARIC) Study." Ann Epidemiol. 1992;2(4):471-80.
Wu C, Demerath EW, Pankow JS, et al. "Imputation of missing covariate values in epigenome-wide analysis of DNA methylation data." Epigenetics. 2016;11(2):132-9.
Wu B, Pankow JS. "Sequence Kernel Association Analysis of Rare Variant Set Based on the Marginal Regression Model for Binary Traits." Genet Epidemiol. 2015;39(6):399-405.
Wu KK, Papp AC, Patsch W, Rock R, Eckfeldt J, Sharrett R. "ARIC hemostasis study--II. Organizational plan and feasibility study." Thromb Haemost. 1990;64(4):521-5.
Wu B. "Statistical methods for association tests of multiple continuous traits in genome-wide association studies." Ann Hum Genet. 2015;79(4):282-93.
Wu B. "Sequence Kernel Association Test of Multiple Continuous Phenotypes." Genet Epidemiol. 2016;40(2):91-100.
Wu A, Sharrett ARichey, Gottesman RF, et al. "Association of Brain Magnetic Resonance Imaging Signs With Cognitive Outcomes in Persons With Nonimpaired Cognition and Mild Cognitive Impairment." JAMA Netw Open. 2019;2(5):e193359.
Wright JD, Folsom AR, Coresh J, et al. "The ARIC (Atherosclerosis Risk In Communities) Study: JACC Focus Seminar 3/8." J Am Coll Cardiol. 2021;77(23):2939-2959.
Wormser D, White IR, Thompson SG. "Within-person variability in calculated risk factors: comparing the aetiological association of adiposity ratios with risk of coronary heart disease." Int J Epidemiol. 2013;42(3):849-59.
Wood AR, Esko T, Yang J, et al. "Defining the role of common variation in the genomic and biological architecture of adult human height." Nat Genet. 2014;46(11):1173-86.
Wong TY, Klein R, Couper DJ, et al. "Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study." Lancet. 2001;358(9288):1134-40.
Wong T Y, Coresh J, Klein R, et al. "Retinal microvascular abnormalities and renal dysfunction: the atherosclerosis risk in communities study." J Am Soc Nephrol. 2004;15(9):2469-76.
Wong T Y, Tikellis G, Sun C, Klein R, Couper DJ, A Sharrett R. "Age-related macular degeneration and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study." Ophthalmology. 2007;114(1):86-91.
Wong TY, Mosley TH, Klein R, et al. "Retinal microvascular changes and MRI signs of cerebral atrophy in healthy, middle-aged people." Neurology. 2003;61(6):806-11.
Wong T Y, Klein R, A Sharrett R, et al. "Retinal arteriolar narrowing and risk of coronary heart disease in men and women. The Atherosclerosis Risk in Communities Study." JAMA. 2002;287(9):1153-9.
Wong T Y, Klein R, A Sharrett R, et al. "Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons." JAMA. 2002;287(19):2528-33.
Wong T Y, Klein R, Duncan BB, et al. "Racial differences in the prevalence of hypertensive retinopathy." Hypertension. 2003;41(5):1086-91.
Wong ND, Zhao Y, Patel R, et al. "Cardiovascular Risk Factor Targets and Cardiovascular Disease Event Risk in Diabetes: A Pooling Project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study." Diabetes Care. 2016;39(5):668-76.
Wong T Y, Shankar A, Klein R, et al. "Apolipoprotein E gene and early age-related maculopathy: the Atherosclerosis Risk in Communities Study." Ophthalmology. 2006;113(2):255-9.
Wong T Y, Klein R, A Sharrett R, et al. "Retinal microvascular abnormalities and cognitive impairment in middle-aged persons: the Atherosclerosis Risk in Communities Study." Stroke. 2002;33(6):1487-92.
Wong T Y, Duncan BB, Golden S H, et al. "Associations between the metabolic syndrome and retinal microvascular signs: the Atherosclerosis Risk In Communities study." Invest Ophthalmol Vis Sci. 2004;45(9):2949-54.
Wong TY, Rosamond W, Chang PP, et al. "Retinopathy and risk of congestive heart failure." JAMA. 2005;293(1):63-9.
Wong T Y, Klein R, A Sharrett R, et al. "Retinal arteriolar diameter and risk for hypertension." Ann Intern Med. 2004;140(4):248-55.
Wong E, Ballew SH, Daya N, et al. "Hospitalization Risk among Older Adults with Chronic Kidney Disease." Am J Nephrol. 2019;50(3):212-220.
Wong T Y, Klein R, Sun C, et al. "Age-related macular degeneration and risk for stroke." Ann Intern Med. 2006;145(2):98-106.
Wong T Y, Klein R, Nieto JF, et al. "Is early age-related maculopathy related to cognitive function? The Atherosclerosis Risk in Communities Study." Am J Ophthalmol. 2002;134(6):828-35.
Wong TY, Klein R, Amirul Islam FM, et al. "Three-year incidence and cumulative prevalence of retinopathy: the atherosclerosis risk in communities study." Am J Ophthalmol. 2007;143(6):970-6.
Wong T Y, Klein R, A Sharrett R, et al. "Cerebral white matter lesions, retinopathy, and incident clinical stroke." JAMA. 2002;288(1):67-74.
Wojcik GL, Graff M, Nishimura KK, et al. "Genetic analyses of diverse populations improves discovery for complex traits." Nature. 2019;570(7762):514-518.
Wofford MR, Andrew ME, Brown A, et al. "Obesity Hypertension in the Atherosclerosis Risk in Communities Cohort: Implications of Obesity Guidelines." J Clin Hypertens (Greenwich). 1999;1(1):27-32.
Witt LS, Rotter J, Stearns SC, et al. "Heart Failure and Cognitive Impairment in the Atherosclerosis Risk in Communities (ARIC) Study." J Gen Intern Med. 2018;33(10):1721-1728.
Wirka RC, Gore S, Van Wagoner DR, et al. "A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation." Circ Arrhythm Electrophysiol. 2011;4(1):87-93.
Winkler TW, Justice AE, Graff M, et al. "The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2015;11(10):e1005378.
Winkler TW, Justice AE, Graff M, et al. "Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2016;12(6):e1006166.
Winkler TW, Day FR, Croteau-Chonka DC, et al. "Quality control and conduct of genome-wide association meta-analyses." Nat Protoc. 2014;9(5):1192-212.
Winkelman JW, Redline S, Baldwin CM, Resnick HE, Newman AB, Gottlieb DJ. "Polysomnographic and health-related quality of life correlates of restless legs syndrome in the Sleep Heart Health Study." Sleep. 2009;32(6):772-8.
Winkelman JW, Shahar E, Sharief I, Gottlieb DJ. "Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study." Neurology. 2008;70(1):35-42.
B Windham G, Griswold ME, Wang W, et al. "The Importance of Mid-to-Late-Life Body Mass Index Trajectories on Late-Life Gait Speed." J Gerontol A Biol Sci Med Sci. 2017;72(8):1130-1136.

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