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ARIC Publications

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2021
McCartney DL, Min JL, Richmond RC, et al. "Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging." Genome Biol. 2021;22(1):194.
McCartney DL, Min JL, Richmond RC, et al. "Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging." Genome Biol. 2021;22(1):194.
McCartney DL, Min JL, Richmond RC, et al. "Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging." Genome Biol. 2021;22(1):194.
Ahluwalia TS, Prins BP, Abdollahi M, et al. "Genome-wide association study of circulating interleukin 6 levels identifies novel loci." Hum Mol Genet. 2021;30(5):393-409.
Ahluwalia TS, Prins BP, Abdollahi M, et al. "Genome-wide association study of circulating interleukin 6 levels identifies novel loci." Hum Mol Genet. 2021;30(5):393-409.
Ahluwalia TS, Prins BP, Abdollahi M, et al. "Genome-wide association study of circulating interleukin 6 levels identifies novel loci." Hum Mol Genet. 2021;30(5):393-409.
Ahluwalia TS, Prins BP, Abdollahi M, et al. "Genome-wide association study of circulating interleukin 6 levels identifies novel loci." Hum Mol Genet. 2021;30(5):393-409.
Jones G, Trajanoska K, Santanasto AJ, et al. "Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
Jones G, Trajanoska K, Santanasto AJ, et al. "Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
Jones G, Trajanoska K, Santanasto AJ, et al. "Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
Jones G, Trajanoska K, Santanasto AJ, et al. "Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
Selvin E, Wang D, Tang O, Minotti M, Echouffo-Tcheugui JB, Coresh J. "Glucose Patterns in Very Old Adults: A Pilot Study in a Community-Based Population." Diabetes Technol Ther. 2021.
Echouffo-Tcheugui JB, Daya N, Matsushita K, et al. "Growth Differentiation Factor (GDF)-15 and Cardiometabolic Outcomes among Older Adults: The Atherosclerosis Risk in Communities Study." Clin Chem. 2021;67(4):653-661.
Commodore-Mensah Y, Lazo M, Tang O, et al. "High Burden of Subclinical and Cardiovascular Disease Risk in Adults with Metabolically Healthy Obesity: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2021.
Ebong IA, Wilson MD, Bertoni AG, et al. "High-sensitivity cardiac troponin T and the risk of heart failure in postmenopausal women of the ARIC Study." Menopause. 2021;28(3):284-291.
Qi Q, Li J, Yu B, et al. "Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies." Gut. 2021.
Qi Q, Li J, Yu B, et al. "Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies." Gut. 2021.
Qi Q, Li J, Yu B, et al. "Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies." Gut. 2021.
Qi Q, Li J, Yu B, et al. "Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies." Gut. 2021.
Zhao Y, Malik S, Budoff MJ, et al. "Identification and Predictors for Cardiovascular Disease Risk Equivalents among Adults With Diabetes Mellitus." Diabetes Care. 2021.
Zhao Y, Malik S, Budoff MJ, et al. "Identification and Predictors for Cardiovascular Disease Risk Equivalents among Adults With Diabetes Mellitus." Diabetes Care. 2021.
Sarnowski C, Chen H, Biggs ML, et al. "Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program." PLoS One. 2021;16(7):e0253611.
Sarnowski C, Chen H, Biggs ML, et al. "Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program." PLoS One. 2021;16(7):e0253611.
Sullivan KJ, Ranadive R, Su D, et al. "Imaging-based indices of Neuropathology and gait speed decline in older adults: the atherosclerosis risk in communities study." Brain Imaging Behav. 2021.
Sullivan KJ, Ranadive R, Su D, et al. "Imaging-based indices of Neuropathology and gait speed decline in older adults: the atherosclerosis risk in communities study." Brain Imaging Behav. 2021.
Sarnowski C, Cousminer DL, Franceschini N, et al. "Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche." Hum Reprod. 2021;36(7):1999-2010.
Sarnowski C, Cousminer DL, Franceschini N, et al. "Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche." Hum Reprod. 2021;36(7):1999-2010.
Krishnappa D, Wang W, Rooney MR, et al. "Life's Simple 7 cardiovascular health score and premature atrial contractions: The atherosclerosis risk in communities (ARIC) study." Int J Cardiol. 2021.
Xu H, Schwander K, Brown MR, et al. "Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions." Eur J Hum Genet. 2021;29(5):839-850.
Xu H, Schwander K, Brown MR, et al. "Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions." Eur J Hum Genet. 2021;29(5):839-850.
Metcalf PA, Meyer ML, Tanaka H, et al. "Longitudinal associations of blood pressure with aortic stiffness and pulsatility: the Atherosclerosis Risk in Communities Study." J Hypertens. 2021;39(5):987-993.
Ting J, Jiang K, Du S, et al. "Longitudinal Blood Pressure Patterns from Mid-to-Late Life and Late-life Hearing Loss in the Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2021.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Gorski M, Jung B, Li Y, et al. "Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline." Kidney Int. 2021;99(4):926-939.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Wang H, Noordam R, Cade BE, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Mol Psychiatry. 2021.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Madrid L, Moreno-Grau S, Ahmad S, et al. "Multiomics integrative analysis identifies allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis." Aging (Albany NY). 2021;13(7):9277-9329.
Walker KA, Chawla S, Nogueras-Ortiz C, et al. "Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study." Neurobiol Aging. 2021;97:65-72.
Walker KA, Chawla S, Nogueras-Ortiz C, et al. "Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study." Neurobiol Aging. 2021;97:65-72.
Kahali B, Chen Y, Feitosa MF, et al. "A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction." J Clin Endocrinol Metab. 2021;106(2):372-387.
Fang M, Tcheugui JBEchouffo, Pankow JS, B Windham G, Selvin E. "Patient-reported preventive care practices in older adults with diabetes." Diabet Med. 2021;38(3):e14508.
Pandey A, Mehta A, Paluch A, et al. "Performance of the American Heart Association/American College of Cardiology Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Self-reported Physical Activity Levels." JAMA Cardiol. 2021;6(6):690-696.
Zhang S, Philips KH, Moss K, et al. "Periodontitis and Risk of Diabetes in the Atherosclerosis Risk In Communities (ARIC) Study: A BMI-modified Association." J Clin Endocrinol Metab. 2021.
Damotte V, van der Lee SJ, Chouraki V, et al. "Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants." Alzheimers Dement. 2021.
Lindbohm JV, Mars N, Walker KA, et al. "Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies." Alzheimers Dement. 2021.
Lindbohm JV, Mars N, Walker KA, et al. "Plasma proteins, cognitive decline, and 20-year risk of dementia in the Whitehall II and Atherosclerosis Risk in Communities studies." Alzheimers Dement. 2021.
Seplyarskiy VB, Soldatov RA, Koch E, et al. "Population sequencing data reveal a compendium of mutational processes in the human germ line." Science. 2021;373(6558):1030-1035.
Seplyarskiy VB, Soldatov RA, Koch E, et al. "Population sequencing data reveal a compendium of mutational processes in the human germ line." Science. 2021;373(6558):1030-1035.
Briceño EM, Gross AL, Giordani BJ, et al. "Pre-Statistical Considerations for Harmonization of Cognitive Instruments: Harmonization of ARIC, CARDIA, CHS, FHS, MESA, and NOMAS." J Alzheimers Dis. 2021.
Schneider ALC, Wang D, Gottesman RF, Selvin E. "Prevalence of Disability Associated With Head Injury With Loss of Consciousness in Adults in the United States: A Population-Based Study." Neurology. 2021;97(2):e124-e135.
Hicks CW, Wang D, B Windham G, Matsushita K, Selvin E. "Prevalence of peripheral neuropathy defined by monofilament insensitivity in middle-aged and older adults in two US cohorts." Sci Rep. 2021;11(1):19159.
Hicks CW, Wang D, B Windham G, Matsushita K, Selvin E. "Prevalence of peripheral neuropathy defined by monofilament insensitivity in middle-aged and older adults in two US cohorts." Sci Rep. 2021;11(1):19159.
Grams ME, Surapaneni A, Chen J, et al. "Proteins Associated with Risk of Kidney Function Decline in the General Population." J Am Soc Nephrol. 2021;32(9):2291-2302.
Choi SHoan, Jurgens SJ, Haggerty CM, et al. "Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis." Circ Genom Precis Med. 2021;14(4):e003300.
Choi SHoan, Jurgens SJ, Haggerty CM, et al. "Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis." Circ Genom Precis Med. 2021;14(4):e003300.
Choi SHoan, Jurgens SJ, Haggerty CM, et al. "Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis." Circ Genom Precis Med. 2021;14(4):e003300.
Griswold ME, Talluri R, Zhu X, et al. "Reflection on modern methods: shared-parameter models for longitudinal studies with missing data." Int J Epidemiol. 2021;50(4):1384-1393.
Caughey MC, Qiao Y, Meyer ML, et al. "Relationship Between Central Artery Stiffness, Brain Arterial Dilation, and White Matter Hyperintensities in Older Adults: The ARIC Study-Brief Report." Arterioscler Thromb Vasc Biol. 2021;41(6):2109-2116.
Quispe R, Martin SS, Michos ED, et al. "Remnant cholesterol predicts cardiovascular disease beyond LDL and ApoB: a primary prevention study." Eur Heart J. 2021.

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