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ARIC Publications

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Adams HHH, Hibar DP, Chouraki V, et al. "Novel genetic loci underlying human intracranial volume identified through genome-wide association." Nat Neurosci. 2016;19(12):1569-1582.
Jensen RA, Sim X, Smith A V, et al. "Novel Genetic Loci Associated With Retinal Microvascular Diameter." Circ Cardiovasc Genet. 2016;9(1):45-54.
Hibar DP, Adams HHH, Jahanshad N, et al. "Novel genetic loci associated with hippocampal volume." Nat Commun. 2017;8:13624.
Feitosa MF, Kraja AT, Chasman DI, et al. "Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries." PLoS One. 2018;13(6):e0198166.
Holmes MV, Exeter HJ, Folkersen L, et al. "Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels." Circ Cardiovasc Genet. 2014;7(2):144-50.
Smith NL, Chen M-H, Dehghan A, et al. "Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium." Circulation. 2010;121(12):1382-92.
Geurts YM, Dugué P-A, Joo JE, et al. "Novel associations between blood DNA methylation and body mass index in middle-aged and older adults." Int J Obes (Lond). 2018;42(4):887-896.
Huxley RR, Lopez FL, Maclehose RF, et al. "Novel association between plasma matrix metalloproteinase-9 and risk of incident atrial fibrillation in a case-cohort study: the Atherosclerosis Risk in Communities study." PLoS One. 2013;8(3):e59052.
Hoggart CJ, Venturini G, Mangino M, et al. "Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index." PLoS Genet. 2014;10(7):e1004508.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, et al. "A novel Alzheimer disease locus located near the gene encoding tau protein." Mol Psychiatry. 2016;21(1):108-17.
Lee CR, North KE, Bray MS, et al. "NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study." Pharmacogenet Genomics. 2006;16(12):891-9.
Chu AY, Coresh J, Arking DE, et al. "NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2010;53(3):510-6.
Schneider ALC, Sharrett ARichey, Gottesman RF, et al. "Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study." Alzheimer Dis Assoc Disord. 2015;29(1):32-44.
Saito I, Folsom AR, Brancati FL, Duncan BB, Chambless LE, McGovern PG. "Nontraditional risk factors for coronary heart disease incidence among persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Ann Intern Med. 2000;133(2):81-91.
Chatterjee R, Brancati FL, Shafi T, et al. "Non-traditional risk factors are important contributors to the racial disparity in diabetes risk: the atherosclerosis risk in communities study." J Gen Intern Med. 2014;29(2):290-7.
Selvin E, Francis LMA, Ballantyne CM, et al. "Nontraditional markers of glycemia: associations with microvascular conditions." Diabetes Care. 2011;34(4):960-7.
Salomaa V, Riley W, Kark JD, Nardo C, Folsom AR. "Non-insulin-dependent diabetes mellitus and fasting glucose and insulin concentrations are associated with arterial stiffness indexes. The ARIC Study. Atherosclerosis Risk in Communities Study." Circulation. 1995;91(5):1432-43.
Kahali B, Chen Y, Feitosa MF, et al. "A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction." J Clin Endocrinol Metab. 2021;106(2):372-387.
McGovern PG, Shahar E, Folsom AR, Rosamond WD. "No relation between excess fatigue and asymptomatic carotid atherosclerosis." Epidemiology. 1996;7(6):638-40.
Selvin E, Rawlings AM, Bergenstal RM, Coresh J, Brancati FL. "No racial differences in the association of glycated hemoglobin with kidney disease and cardiovascular outcomes." Diabetes Care. 2013;36(10):2995-3001.
Folsom AR, de Vries PS, Cushman M. "No prospective association of a polygenic risk score for coronary artery disease with venous thromboembolism incidence." J Thromb Haemost. 2021.
Scott RA, Chu AY, Grarup N, et al. "No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels." Diabetes. 2012;61(5):1291-6.
Dumitrescu L, Carty CL, Franceschini N, et al. "No evidence of interaction between known lipid-associated genetic variants and smoking in the multi-ethnic PAGE population." Hum Genet. 2013;132(12):1427-31.
Nabulsi AA, Folsom AR, Szklo M, White A, Higgins M, Heiss G. "No association of menopause and hormone replacement therapy with carotid artery intima-media thickness. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Circulation. 1996;94(8):1857-63.
Carrejo MH, Sharrett R, Patsch W, Boerwinkle E. "No association of apolipoprotein A-IV codon 347 and 360 variation with atherosclerosis and lipid transport in a sample of mixed hyperlipidemics." Genet Epidemiol. 1995;12(4):371-80.
George KM, Folsom AR, Norby FL. "No Association Found Between Midlife Seropositivity for Infection and Subsequent Cognitive Decline: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Geriatr Psychiatry Neurol. 2020;33(1):15-21.
Moore M, Folsom AR, Barnes RW, Eckfeldt JH. "No association between serum ferritin and asymptomatic carotid atherosclerosis. The Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1995;141(8):719-23.
Love S-AM, North KE, Zeng D, et al. "Nine-Year Ethanol Intake Trajectories and Their Association With 15-Year Cognitive Decline Among Black and White Adults." Am J Epidemiol. 2020;189(8):788-800.
Truesdale KP, Stevens J, Cai J. "Nine-year changes in cardiovascular disease risk factors with weight maintenance in the atherosclerosis risk in communities cohort." Am J Epidemiol. 2007;165(8):890-900.
Lazo M, Young HJ, Brancati FL, et al. "NH2-terminal pro-brain natriuretic peptide and risk of diabetes." Diabetes. 2013;62(9):3189-93.
Preisser JS, Marks SJ, Sanders AE, Akinkugbe AA. "A new way to estimate disease prevalence from random partial-mouth samples." J Clin Periodontol. 2017;44(3):283-289.
Folsom AR. ""New" risk factors for atherosclerotic diseases." Exp Gerontol. 1999;34(4):483-90.
Lu Y, Day FR, Gustafsson S, et al. "New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk." Nat Commun. 2016;7:10495.
Köttgen A, Pattaro C, Böger CA, et al. "New loci associated with kidney function and chronic kidney disease." Nat Genet. 2010;42(5):376-84.
Shungin D, Winkler TW, Croteau-Chonka DC, et al. "New genetic loci link adipose and insulin biology to body fat distribution." Nature. 2015;518(7538):187-196.
Kraja AT, Cook JP, Warren HR, et al. "New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals." Circ Cardiovasc Genet. 2017;10(5).
Gogoshin G, Boerwinkle E. "New Algorithm and Software (BNOmics) for Inferring and Visualizing Bayesian Networks from Heterogeneous Big Biological and Genetic Data." J Comput Biol. 2017;24(4):340-356.
Evangelou E, Gao H, Chu C, et al. "New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders." Nat Hum Behav. 2019;3(9):950-961.
Bhavsar NA, Köttgen A, Coresh J, Astor BC. "Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule 1 (KIM-1) as predictors of incident CKD stage 3: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2012;60(2):233-40.
Walker KA, Chawla S, Nogueras-Ortiz C, et al. "Neuronal insulin signaling and brain structure in nondemented older adults: the Atherosclerosis Risk in Communities Study." Neurobiol Aging. 2021;97:65-72.
West NA, B Windham G, Knopman DS, Shibata DK, Coker LH. "Neuroimaging findings in midlife and risk of late-life dementia over 20 years of follow-up." Neurology. 2019;92(9):e917-e923.
Graff-Radford J, Simino J, Kantarci K, et al. "Neuroimaging Correlates of Cerebral Microbleeds: The ARIC Study (Atherosclerosis Risk in Communities)." Stroke. 2017;48(11):2964-2972.
Schneider ALC, Senjem ML, Wu A, et al. "Neural correlates of domain-specific cognitive decline: The ARIC-NCS Study." Neurology. 2019;92(10):e1051-e1063.
Kummer AE, Grams M, Lutsey PL, et al. "Nephrolithiasis as a Risk Factor for CKD: The Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(11):2023-9.
van Lenthe FJ, Borrell LN, Costa G, et al. "Neighbourhood unemployment and all cause mortality: a comparison of six countries." J Epidemiol Community Health. 2005;59(3):231-7.
Diez-Roux AV, Nieto FJ, Caulfield L, Tyroler HA, Watson RL, Szklo M. "Neighbourhood differences in diet: the Atherosclerosis Risk in Communities (ARIC) Study." J Epidemiol Community Health. 1999;53(1):55-63.
Borrell LN, Diez Roux AV, Rose K, Catellier D, Clark BL. "Neighbourhood characteristics and mortality in the Atherosclerosis Risk in Communities Study." Int J Epidemiol. 2004;33(2):398-407.
Foraker RE, Rose KM, Whitsel EA, Suchindran CM, Wood JL, Rosamond WD. "Neighborhood socioeconomic status, Medicaid coverage and medical management of myocardial infarction: atherosclerosis risk in communities (ARIC) community surveillance." BMC Public Health. 2010;10:632.
Foraker RE, Patel MD, Whitsel EA, Suchindran CM, Heiss G, Rose KM. "Neighborhood socioeconomic disparities and 1-year case fatality after incident myocardial infarction: the Atherosclerosis Risk in Communities (ARIC) Community Surveillance (1992-2002)." Am Heart J. 2013;165(1):102-7.
Rose KM, Foraker RE, Heiss G, Rosamond WD, Suchindran CM, Whitsel EA. "Neighborhood socioeconomic and racial disparities in angiography and coronary revascularization: the ARIC surveillance study." Ann Epidemiol. 2012;22(9):623-9.
Diez Roux AV, Merkin SS, Arnett D, et al. "Neighborhood of residence and incidence of coronary heart disease." N Engl J Med. 2001;345(2):99-106.
Foraker RE, Rose KM, McGinn AP, et al. "Neighborhood income, health insurance, and prehospital delay for myocardial infarction: the atherosclerosis risk in communities study." Arch Intern Med. 2008;168(17):1874-9.
Diez-Roux AV, Nieto FJ, Muntaner C, et al. "Neighborhood environments and coronary heart disease: a multilevel analysis." Am J Epidemiol. 1997;146(1):48-63.
Rose KM, Suchindran CM, Foraker RE, et al. "Neighborhood disparities in incident hospitalized myocardial infarction in four U.S. communities: the ARIC surveillance study." Ann Epidemiol. 2009;19(12):867-74.
Morland K, Wing S, Roux ADiez, Poole C. "Neighborhood characteristics associated with the location of food stores and food service places." Am J Prev Med. 2002;22(1):23-9.
Assimes TL, Knowles JW, Priest JR, et al. "A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease." Atherosclerosis. 2008;198(1):136-44.
Willeit P, Kaptoge S, Welsh P, et al. "Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis." Lancet Diabetes Endocrinol. 2016;4(10):840-9.
Gori M, Gupta DK, Claggett B, et al. "Natriuretic Peptide and High-Sensitivity Troponin for Cardiovascular Risk Prediction in Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):677-85.
Beydoun MA, Kaufman JS, Sloane PD, Heiss G, Ibrahim J. "n-3 Fatty acids, hypertension and risk of cognitive decline among older adults in the Atherosclerosis Risk in Communities (ARIC) study." Public Health Nutr. 2008;11(1):17-29.
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Pokharel Y, Sun W, Virani SS, et al. "Myocardial Injury, Obesity, and the Obesity Paradox: The ARIC Study." JACC Heart Fail. 2017;5(1):56-63.
O'Seaghdha CM, Parekh RS, Hwang S-J, et al. "The MYH9/APOL1 region and chronic kidney disease in European-Americans." Hum Mol Genet. 2011;20(12):2450-6.
Kapoor A, Lee D, Zhu L, et al. "Multiple variant enhancers modulate its cardiac gene expression and the QT interval." Proc Natl Acad Sci U S A. 2019;116(22):10636-10645.
Liao D, Sloan RP, Cascio WE, et al. "Multiple metabolic syndrome is associated with lower heart rate variability. The Atherosclerosis Risk in Communities Study." Diabetes Care. 1998;21(12):2116-22.
Ganesh SK, Zakai NA, van Rooij FJA, et al. "Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium." Nat Genet. 2009;41(11):1191-8.
Köttgen A, Glazer NL, Dehghan A, et al. "Multiple loci associated with indices of renal function and chronic kidney disease." Nat Genet. 2009;41(6):712-7.
Nalls MA, Couper DJ, Tanaka T, et al. "Multiple loci are associated with white blood cell phenotypes." PLoS Genet. 2011;7(6):e1002113.
Everett CJ, Mainous AG, Koopman RJ, Diaz VA. "Multiple lipid scoring system for prediction of coronary heart disease risk: application to African Americans." J Natl Med Assoc. 2006;98(11):1740-5.
Arking DE, Khera A, Xing C, et al. "Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population." PLoS One. 2009;4(1):e4333.
Keogh RH, Seaman SR, Bartlett JW. "Multiple imputation of missing data in nested case-control and case-cohort studies." Biometrics. 2018;74(4):1438-1449.
Rawlings AMonica, Sang Y, Sharrett ARichey, et al. "Multiple imputation of cognitive performance as a repeatedly measured outcome." Eur J Epidemiol. 2017;32(1):55-66.
Madrid L, Moreno-Grau S, Ahmad S, et al. "Multiomics integrative analysis identifies allele-specific blood biomarkers associated to Alzheimer's disease etiopathogenesis." Aging (Albany NY). 2021;13(7):9277-9329.
Tangri N, Grams ME, Levey AS, et al. "Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis." JAMA. 2016;315(2):164-74.
Sabater-Lleal M, Huang J, Chasman D, et al. "Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease." Circulation. 2013;128(12):1310-24.
Wyss AB, Sofer T, Lee MKyeong, et al. "Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function." Nat Commun. 2018;9(1):2976.
Baldassari AR, Sitlani CM, Highland HM, et al. "Multi-Ethnic Genome-Wide Association Study of Decomposed Cardioelectric Phenotypes Illustrates Strategies to Identify and Characterize Evidence of Shared Genetic Effects for Complex Traits." Circ Genom Precis Med. 2020;13(4):e002680.
Verhaaren BFJ, Debette S, Bis JC, et al. "Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI." Circ Cardiovasc Genet. 2015;8(2):398-409.
Roselli C, Chaffin MD, Weng L-C, et al. "Multi-ethnic genome-wide association study for atrial fibrillation." Nat Genet. 2018;50(9):1225-1233.
Liu C-T, Buchkovich ML, Winkler TW, et al. "Multi-ethnic fine-mapping of 14 central adiposity loci." Hum Mol Genet. 2014;23(17):4738-44.
Natarajan P, Bis JC, Bielak LF, et al. "Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis." Circ Cardiovasc Genet. 2016;9(6):511-520.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.

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