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ARIC Publications

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Hu EA, Steffen LM, Coresh JJ, Appel LJ. "Adherence to the Healthy Eating Index-2015 and Other Dietary Patterns May Reduce Risk of Cardiovascular Disease, Cardiovascular Mortality, and All-Cause Mortality." J Nutr. 2020;150(2):312-321.
Hu Y-J, Berndt SI, Gustafsson S, et al. "Meta-analysis of gene-level associations for rare variants based on single-variant statistics." Am J Hum Genet. 2013;93(2):236-48.
Hu EA, Selvin E, Grams ME, Steffen LM, Coresh JJ. "Coffee Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2018;72(2):214-222.
Hu Y, Stilp AM, McHugh CP, et al. "Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program." Am J Hum Genet. 2021;108(6):1165.
Hu EA, Wu A, Dearborn JL, et al. "Adherence to Dietary Patterns and Risk of Incident Dementia: Findings from the Atherosclerosis Risk in Communities Study." J Alzheimers Dis. 2020;78(2):827-835.
Hu EA, Lazo M, Rosenberg SD, Grams ME, Steffen LM, Coresh JJ. "Alcohol Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities Study." J Ren Nutr. 2020;30(1):22-30.
Hu EA, Steffen LM, Grams ME, Crews DC, Coresh JJ, Appel LJ. "Dietary patterns and risk of incident chronic kidney disease: the Atherosclerosis Risk in Communities study." Am J Clin Nutr. 2019;110(3):713-721.
Hu EA, Lazo M, Selvin E, et al. "Coffee consumption and liver-related hospitalizations and deaths in the ARIC study." Eur J Clin Nutr. 2019;73(8):1133-1140.
Hua S, Loehr LR, Tanaka H, Heiss G, Coresh JJ, Selvin E. "Ankle-brachial index and incident diabetes mellitus: the atherosclerosis risk in communities (ARIC) study." Cardiovasc Diabetol. 2016;15(1):163.
Huan T, Joehanes R, Song C, et al. "Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease." Nat Commun. 2019;10(1):4267.
Huang Z, Rustagi N, Veeraraghavan N, et al. "A hybrid computational strategy to address WGS variant analysis in >5000 samples." BMC Bioinformatics. 2016;17(1):361.
Huang J, Wang K, Wei P, et al. "FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics." Genetics. 2016;202(3):919-29.
Huang X, Alonso A, Guo X, et al. "Statins, plasma cholesterol, and risk of Parkinson's disease: a prospective study." Mov Disord. 2015;30(4):552-9.
Huang H, Chanda P, Alonso A, Bader JS, Arking DE. "Gene-based tests of association." PLoS Genet. 2011;7(7):e1002177.
Huang J, Sabater-Lleal M, Asselbergs FW, et al. "Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation." Blood. 2012;120(24):4873-81.
Huang M, Matsushita K, Sang Y, Ballew SH, Astor BC. "Association of kidney function and albuminuria with prevalent and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(1):58-66.
Huang J, Huffman JE, Yamakuchi M, et al. "Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2." Arterioscler Thromb Vasc Biol. 2014;34(5):1093-101.
Hubbard LD, Brothers RJ, King WN, et al. "Methods for evaluation of retinal microvascular abnormalities associated with hypertension/sclerosis in the Atherosclerosis Risk in Communities Study." Ophthalmology. 1999;106(12):2269-80.
Huffman JE, de Vries PS, Morrison AC, et al. "Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF." Blood. 2015;126(11):e19-29.
Huffman JE, Albrecht E, Teumer A, et al. "Modulation of genetic associations with serum urate levels by body-mass-index in humans." PLoS One. 2015;10(3):e0119752.
Hughes TM, Wagenknecht LE, Craft S, et al. "Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study." Neurology. 2018;90(14):e1248-e1256.
Hui X, Matsushita K, Sang Y, Ballew SH, Fulop T. "CKD and cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study: interactions with age, sex, and race." Am J Kidney Dis. 2013;62(4):691-702.
Hung C-L, Gonçalves A, Shah AM, Cheng S, Kitzman D. "Age- and Sex-Related Influences on Left Ventricular Mechanics in Elderly Individuals Free of Prevalent Heart Failure: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Cardiovasc Imaging. 2017;10(1).
Hunsberger S, Sorlie P, Geller NL. "Stochastic curtailing and conditional power in matched case-control studies." Stat Med. 1994;13(5-7):663-70.
Hunt KJ, Pankow JS, Offenbacher S, et al. "B-mode ultrasound-detected carotid artery lesions with and without acoustic shadowing and their association with markers of inflammation and endothelial activation: the atherosclerosis risk in communities study." Atherosclerosis. 2002;162(1):145-55.
Hunt KJ, Evans GW, Folsom AR, et al. "Acoustic shadowing on B-mode ultrasound of the carotid artery predicts ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2001;32(5):1120-6.
Hunt KJ, Sharrett AR, Chambless LE, Folsom AR, Evans GW, Heiss G. "Acoustic shadowing on B-mode ultrasound of the carotid artery predicts CHD." Ultrasound Med Biol. 2001;27(3):357-65.
Hurwitz LM, Joshu CE, Barber JR, et al. "Aspirin and Non-Aspirin NSAID Use and Prostate Cancer Incidence, Mortality, and Case Fatality in the Atherosclerosis Risk in Communities Study." Cancer Epidemiol Biomarkers Prev. 2019;28(3):563-569.
Hussain A, Sun C, Selvin E, et al. "Triglyceride-rich lipoproteins, apolipoprotein C-III, angiopoietin-like protein 3, and cardiovascular events in older adults: Atherosclerosis Risk in Communities (ARIC) study." Eur J Prev Cardiol. 2021.
Hussain A, Sun W, Deswal A, et al. "Association of NT-ProBNP, Blood Pressure, and Cardiovascular Events: The ARIC Study." J Am Coll Cardiol. 2021;77(5):559-571.
Hussain A, Tang O, Sun C, et al. "Soluble Angiotensin-Converting Enzyme 2, Cardiac Biomarkers, Structure, and Function, and Cardiovascular Events (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2021;146:15-21.
Hutchinson RG, Watson RL, Davis CE, et al. "Racial differences in risk factors for atherosclerosis. The ARIC Study. Atherosclerosis Risk in Communities." Angiology. 1997;48(4):279-90.
Huxley RR, Misialek JR, Agarwal SK, Loehr LR, Soliman EZ, Chen LYee. "Physical activity, obesity, weight change, and risk of atrial fibrillation: the Atherosclerosis Risk in Communities study." Circ Arrhythm Electrophysiol. 2014;7(4):620-5.
Huxley RR, Yatsuya H, Lutsey PL, Woodward M, Alonso A, Folsom AR. "Impact of age at smoking initiation, dosage, and time since quitting on cardiovascular disease in african americans and whites: the atherosclerosis risk in communities study." Am J Epidemiol. 2012;175(8):816-26.
Huxley RR, Alonso A, Lopez FL, et al. "Type 2 diabetes, glucose homeostasis and incident atrial fibrillation: the Atherosclerosis Risk in Communities study." Heart. 2012;98(2):133-8.
Huxley RR, Lopez FL, Maclehose RF, et al. "Novel association between plasma matrix metalloproteinase-9 and risk of incident atrial fibrillation in a case-cohort study: the Atherosclerosis Risk in Communities study." PLoS One. 2013;8(3):e59052.
Huxley RR, Lopez FL, Folsom AR, et al. "Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2011;123(14):1501-8.
Huxley RR, Bell EJ, Lutsey PL, et al. "A comparative analysis of risk factors for stroke in blacks and whites: the Atherosclerosis Risk in Communities study." Ethn Health. 2014;19(6):601-16.
Hwang SJ, Ballantyne CM, Sharrett AR, et al. "Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study." Circulation. 1997;96(12):4219-25.
Hyacinth HI, Franceschini N, Seals SR, et al. "Association of Sickle Cell Trait With Incidence of Coronary Heart Disease Among African American Individuals." JAMA Netw Open. 2021;4(1):e2030435.
Iber C, Redline S, Kaplan Gilpin AM, et al. "Polysomnography performed in the unattended home versus the attended laboratory setting--Sleep Heart Health Study methodology." Sleep. 2004;27(3):536-40.
Ibrahim-Verbaas CA, Fornage M, Bis JC, et al. "Predicting stroke through genetic risk functions: the CHARGE Risk Score Project." Stroke. 2014;45(2):403-12.
M Ikram K, Mitchell P, Klein R, A Sharrett R, Couper DJ, Wong TY. "Age-related macular degeneration and long-term risk of stroke subtypes." Stroke. 2012;43(6):1681-3.
M Ikram A, Seshadri S, Bis JC, et al. "Genomewide association studies of stroke." N Engl J Med. 2009;360(17):1718-28.
Ilkhanoff L, Arking DE, Lemaitre RN, et al. "A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans." J Cardiovasc Electrophysiol. 2014;25(11):1150-7.
Imamura F, Lemaitre RN, King IB, et al. "Long-chain monounsaturated Fatty acids and incidence of congestive heart failure in 2 prospective cohorts." Circulation. 2013;127(14):1512-21, 1521e1-18.
Imboden M, Bouzigon E, Curjuric I, et al. "Genome-wide association study of lung function decline in adults with and without asthma." J Allergy Clin Immunol. 2012;129(5):1218-28.
Inker LA, Grams ME, Levey AS, et al. "Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium." Am J Kidney Dis. 2019;73(2):206-217.
Inker LA, Coresh JJ, Sang Y, et al. "Filtration Markers as Predictors of ESRD and Mortality: Individual Participant Data Meta-Analysis." Clin J Am Soc Nephrol. 2017;12(1):69-78.
"Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis." Lancet Diabetes Endocrinol. 2015;3(4):243-53.
Ehret GB, Munroe PB, Rice KM, et al. "Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk." Nature. 2011;478(7367):103-9.
"Convergent genetic and expression data implicate immunity in Alzheimer's disease." Alzheimers Dement. 2015;11(6):658-71.
Iribarren C, Folsom AR, Jacobs DR, Gross MD, Belcher JD, Eckfeldt JH. "Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. A case-control study. The ARIC Study Investigators. Atherosclerosis Risk in Communities." Arterioscler Thromb Vasc Biol. 1997;17(6):1171-7.
Iribarren C, Sempos CT, Eckfeldt JH, Folsom AR. "Lack of association between ferritin level and measures of LDL oxidation: the ARIC study. Atherosclerosis Risk in Communities." Atherosclerosis. 1998;139(1):189-95.
Iribarren C, Folsom AR, Eckfeldt JH, McGovern PG, Nieto FJ. "Correlates of uric acid and its association with asymptomatic carotid atherosclerosis: the ARIC Study. Atherosclerosis Risk in Communities." Ann Epidemiol. 1996;6(4):331-40.
Irvin MR, Sitlani CM, Floyd JS, et al. "Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group." Am J Hypertens. 2019;32(12):1146-1153.
Irvin MR, Sitlani CM, Noordam R, et al. "Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry." Pharmacogenomics J. 2019;19(1):97-108.
Ishigami J, Mathews L, Hishida M, et al. "Echocardiographic measures and subsequent decline in kidney function in older adults: the Atherosclerosis Risk in Communities Study." Eur Heart J Cardiovasc Imaging. 2021.
Ishigami J, Grams ME, Michos ED, Lutsey PL, Matsushita K. "25-hydroxyvitamin D, Fibroblast Growth Factor 23, and Risk of Acute Kidney Injury Over 20 Years of Follow-Up." Kidney Int Rep. 2021;6(5):1299-1308.
Ishigami J, Grams ME, Naik RP, Coresh JJ. "Chronic Kidney Disease and Risk for Gastrointestinal Bleeding in the Community: The Atherosclerosis Risk in Communities (ARIC) Study." Clin J Am Soc Nephrol. 2016;11(10):1735-1743.
Ishigami J, Padula WV, Grams ME, et al. "Cost-effectiveness of Pneumococcal Vaccination Among Patients With CKD in the United States." Am J Kidney Dis. 2019;74(1):23-35.
Ishigami J, Jaar BG, Rebholz CM, et al. "Biomarkers of Mineral and Bone Metabolism and 20-Year Risk of Hospitalization With Infection: The Atherosclerosis Risk in Communities Study." J Clin Endocrinol Metab. 2017;102(12):4648-4657.
Ishigami J, Cowan LT, Demmer RT, et al. "Incident Hospitalization with Major Cardiovascular Diseases and Subsequent Risk of ESKD: Implications for Cardiorenal Syndrome." J Am Soc Nephrol. 2020;31(2):405-414.
Ishigami J, Kim Y, Sang Y, et al. "High-Sensitivity Cardiac Troponin, Natriuretic Peptide, and Long-Term Risk of Acute Kidney Injury: The Atherosclerosis Risk in Communities (ARIC) Study." Clin Chem. 2021;67(1):298-307.
Ishigami J, Grams ME, Naik RP, et al. "Hemoglobin, Albuminuria, and Kidney Function in Cardiovascular Risk: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(2).
Ishigami J, Karger AB, Lutsey PL, Coresh J, Matsushita K. "Stability of Serum Bone-mineral, Kidney, and Cardiac Biomarkers After a Freeze-thaw Cycle: The ARIC Study." Am J Epidemiol. 2021.
Ishigami J, Cowan LT, Demmer RT, Grams ME, Lutsey PL, Coresh JJ. "Hospitalization With Major Infection and Incidence of End-Stage Renal Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Mayo Clin Proc. 2020;95(9):1928-1939.
Ishigami J, Hoogeveen RC, Ballantyne CM, Folsom AR, Coresh JJ, Selvin E. "Associations of High-Sensitivity Cardiac Troponin and Natriuretic Peptide With Subsequent Risk of Infection in Persons Without Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2019;188(12):2146-2155.
Iso H, Koike KA, Folsom AR, et al. "Lipoprotein(a) and its correlates in Japanese and U.S. population samples." Ann Epidemiol. 1996;6(4):324-30.
Iso H, Folsom AR, Koike KA, et al. "Antigens of tissue plasminogen activator and plasminogen activator inhibitor 1: correlates in nonsmoking Japanese and Caucasian men and women." Thromb Haemost. 1993;70(3):475-80.
Iso H, Harada S, Shimamoto T, et al. "Polymorphism of the apolipoprotein B gene and blood lipid concentrations in Japanese and Caucasian population samples." Atherosclerosis. 1996;126(2):233-41.
Iso H, Folsom AR, Sato S, et al. "Plasma fibrinogen and its correlates in Japanese and US population samples." Arterioscler Thromb. 1993;13(6):783-90.
Jackson VE, Latourelle JC, Wain LV, et al. "Meta-analysis of exome array data identifies six novel genetic loci for lung function." Wellcome Open Res. 2018;3:4.
Jackson R, Chambless LE, Yang K, et al. "Differences between respondents and nonrespondents in a multicenter community-based study vary by gender ethnicity. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." J Clin Epidemiol. 1996;49(12):1441-46.
James MT, Grams ME, Woodward M, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Diabetes Mellitus, and Hypertension With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):602-12.
Jansen H, Willenborg C, Lieb W, et al. "Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation." J Rheumatol. 2017;44(1):4-10.
Jansen H, Loley C, Lieb W, et al. "Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk." Atherosclerosis. 2015;241(2):419-26.
Jaspers NEM, Blaha MJ, Matsushita K, et al. "Prediction of individualized lifetime benefit from cholesterol lowering, blood pressure lowering, antithrombotic therapy, and smoking cessation in apparently healthy people." Eur Heart J. 2020;41(11):1190-1199.
Jehn ML, Guallar E, Clark JM, et al. "A prospective study of plasma ferritin level and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 2007;165(9):1047-54.
Jensen PN, Gronroos NN, Chen LYee, Folsom AR, deFilippi C, Heckbert SR. "Incidence of and risk factors for sick sinus syndrome in the general population." J Am Coll Cardiol. 2014;64(6):531-8.