ARIC Publications
Genome-wide association study of retinopathy in individuals without diabetes." PLoS One. 2013;8(2):e54232.
"Association of Left Ventricular Systolic Function With Incident Heart Failure in Late Life." JAMA Cardiol. 2021.
"Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium." Hum Mol Genet. 2017;26(11):2156-2163.
"A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
"Response by Jia et al to Letter Regarding Article, "High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study"." Circulation. 2019;140(20):e772-e773.
"Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women." J Clin Endocrinol Metab. 2020;105(12).
"Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2022;350:82-89.
" "Subclinical cardiovascular disease and frailty risk: the atherosclerosis risk in communities study." BMC Geriatr. 2022;22(1):321.
"High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study." Circulation. 2019;139(23):2642-2653.
"Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos." Transl Psychiatry. 2020;10(1):245.
"Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging." Stroke. 2018;49(8):1812-1819.
"Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels." Nat Commun. 2018;9(1):260.
"Relation of Diabetes Mellitus to Incident Dementia in Patients With Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2022;165:51-57.
"Epigenetic Signatures of Cigarette Smoking." Circ Cardiovasc Genet. 2016;9(5):436-447.
"Associations Between Left Ventricular Structure, Function, and Cerebral Amyloid: The ARIC-PET Study." Stroke. 2019;50(12):3622-3624.
"Cerebral Small-Vessel Disease in Individuals with a Family History of Coronary Heart Disease: The Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2021;55(4):316-322.
"Associations Between Atrial Cardiopathy and Cerebral Amyloid: The ARIC-PET Study." J Am Heart Assoc. 2020;9(24):e018399.
"Associations Between Atrial Arrhythmias and Brain Amyloid Deposition: The ARIC-PET Study." J Alzheimers Dis. 2022;86(1):43-48.
"Risk of Dementia Associated With Atrial Cardiopathy: The ARIC Study." J Am Heart Assoc. 2022;11(16):e025646.
"Associations of Echocardiography Markers and Vascular Brain Lesions: The ARIC Study." J Am Heart Assoc. 2018;7(24):e008992.
"Coronary Artery Disease and Heart Failure With Preserved Ejection Fraction: The ARIC Study." J Am Heart Assoc. 2022;11(17):e021660.
"Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project." Blood. 2013;122(4):590-7.
"Late-onset epilepsy and 25-year cognitive change: The Atherosclerosis Risk in Communities (ARIC) study." Epilepsia. 2020;61(8):1764-1773.
"Mortality in Patients With Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study." Neurology. 2021.
"Military combat and burden of subclinical atherosclerosis in middle aged men: the ARIC study." Prev Med. 2010;50(5-6):277-81.
"Dementia in late-onset epilepsy: The Atherosclerosis Risk in Communities study." Neurology. 2020;95(24):e3248-e3256.
"Military combat and risk of coronary heart disease and ischemic stroke in aging men: The Atherosclerosis Risk in Communities (ARIC) study." Ann Epidemiol. 2010;20(2):143-50.
"Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals." Hypertension. 2011;57(5):903-10.
"Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study." JAMA Neurol. 2018;75(11):1375-1382.
"Association between white matter hyperintensities, cortical volumes, and late-onset epilepsy." Neurology. 2019;92(9):e988-e995.
"Electrophysiological ventricular substrate of stroke: a prospective cohort study in the Atherosclerosis Risk in Communities (ARIC) study." BMJ Open. 2021;11(9):e048542.
"Validity of hospital discharge diagnosis codes for stroke: the Atherosclerosis Risk in Communities Study." Stroke. 2014;45(11):3219-25.
"Orthostatic hypotension as a risk factor for incident heart failure: the atherosclerosis risk in communities study." Hypertension. 2012;59(5):913-8.
"Midlife Alcohol Consumption and the Risk of Stroke in the Atherosclerosis Risk in Communities Study." Stroke. 2015;46(11):3124-30.
"Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women." Nat Commun. 2021;12(1):654.
"Risk factors for coronary heart disease in African Americans: the atherosclerosis risk in communities study, 1987-1997." Arch Intern Med. 2002;162(22):2565-71.
"Poststroke outcomes vary by pathogenic stroke subtype in the Atherosclerosis Risk in Communities Study." Stroke. 2013;44(8):2307-10.
"Directional dominance on stature and cognition in diverse human populations." Nature. 2015;523(7561):459-462.
"Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity." Nat Commun. 2017;8(1):910.
"Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies." Gastroenterology. 2016;151(2):351-363.e28.
"Enhancing the Infrastructure of the Atherosclerosis Risk in Communities (ARIC) Study for Cancer Epidemiology Research: ARIC Cancer." Cancer Epidemiol Biomarkers Prev. 2018;27(3):295-305.
"Glycated hemoglobin and cancer incidence and mortality in the Atherosclerosis in Communities (ARIC) Study, 1990-2006." Int J Cancer. 2012;131(7):1667-77.
"DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies." JAMA Psychiatry. 2018;75(9):949-959.
"Association of Carotenoid Intake with Pulmonary Function." J Am Coll Nutr. 2021;40(8):708-712.
"A novel Alzheimer disease locus located near the gene encoding tau protein." Mol Psychiatry. 2016;21(1):108-17.
"Performance of non-traditional hyperglycemia biomarkers by chronic kidney disease status in older adults with diabetes: Results from the Atherosclerosis Risk in Communities Study." J Diabetes. 2018;10(4):276-285.
"Plasma lactate and incident hypertension in the atherosclerosis risk in communities study." Am J Hypertens. 2015;28(2):216-24.
"Orthostatic Hypotension and Risk of Clinical and Subclinical Cardiovascular Disease in Middle-Aged Adults." J Am Heart Assoc. 2018;7(10).
"Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults." JAMA Intern Med. 2017;177(9):1316-1323.
"Plasma lactate and diabetes risk in 8045 participants of the atherosclerosis risk in communities study." Ann Epidemiol. 2013;23(12):791-796.e4.
"Temporal relationship between uric acid concentration and risk of diabetes in a community-based study population." Am J Epidemiol. 2014;179(6):684-91.
"Alternative markers of hyperglycemia and risk of diabetes." Diabetes Care. 2012;35(11):2265-70.
"Orthostatic Hypotension in Middle-Age and Risk of Falls." Am J Hypertens. 2017;30(2):188-195.
"Lactate and risk of incident diabetes in a case-cohort of the atherosclerosis risk in communities (ARIC) study." PLoS One. 2013;8(1):e55113.
"Subclinical Cardiovascular Disease and Fall Risk in Older Adults: Results From the Atherosclerosis Risk in Communities Study." J Am Geriatr Soc. 2019;67(9):1795-1802.
"Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution." Nat Genet. 2019;51(3):452-469.
"Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits." Nat Commun. 2017;8:14977.
"Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems." Epigenomics. 2020;12(17):1483-1499.
"A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction." J Clin Endocrinol Metab. 2021;106(2):372-387.
"Frequency of Care and Mortality Following an Incident Diagnosis of Peripheral Artery Disease in the Inpatient or Outpatient Setting: The ARIC (Atherosclerosis Risk in Communities) Study." J Am Heart Assoc. 2018;7(8).
"Peripheral Artery Disease Prevalence and Incidence Estimated From Both Outpatient and Inpatient Settings Among Medicare Fee-for-Service Beneficiaries in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2017;6(5).
"The Neuroanatomic Correlates of Olfactory Identification Impairment in Healthy Older Adults and in Persons with Mild Cognitive Impairment." J Alzheimers Dis. 2022;89(1):233-245.
"Electrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities study." Ann Neurol. 2015;78(5):670-8.
"Dietary fiber, lung function, and chronic obstructive pulmonary disease in the atherosclerosis risk in communities study." Am J Epidemiol. 2008;167(5):570-8.
"Prospective analysis of traffic exposure as a risk factor for incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study." Environ Health Perspect. 2008;116(11):1463-8.
"Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
"Traffic exposure and incident venous thromboembolism in the Atherosclerosis Risk in Communities (ARIC) Study." J Thromb Haemost. 2011;9(4):672-8.
"Traffic exposure and lung function in adults: the Atherosclerosis Risk in Communities study." Thorax. 2007;62(10):873-9.
"Marginal additive hazards model for case-cohort studies with multiple disease outcomes: an application to the Atherosclerosis Risk in Communities (ARIC) study." Biostatistics. 2013;14(1):28-41.
"Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis." Diabetes. 2011;60(9):2407-16.
"Replication and fine mapping of asthma-associated loci in individuals of African ancestry." Hum Genet. 2013;132(9):1039-47.
"Alcohol consumption and the risk of type 2 diabetes mellitus: atherosclerosis risk in communities study." Am J Epidemiol. 2001;154(8):748-57.
"Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study." Diabetes. 2003;52(6):1568-72.
"Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations." Circulation. 2009;119(7):940-51.
"Serum and dietary magnesium and the risk for type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study." Arch Intern Med. 1999;159(18):2151-9.
"An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval." Am J Hum Genet. 2014;94(6):854-69.
"Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
"Multiple variant enhancers modulate its cardiac gene expression and the QT interval." Proc Natl Acad Sci U S A. 2019;116(22):10636-10645.
"Sleepiness in patients with moderate to severe sleep-disordered breathing." Sleep. 2005;28(4):472-7.
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