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ARIC Publications

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van der Velde M, Matsushita K, Coresh J, et al. "Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts." Kidney Int. 2011;79(12):1341-52.
Gansevoort RT, Matsushita K, van der Velde M, et al. "Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts." Kidney Int. 2011;80(1):93-104.
Chamberlain AM, Folsom AR, Schreiner PJ, Boerwinkle E, Ballantyne CM. "Low-density lipoprotein and high-density lipoprotein cholesterol levels in relation to genetic polymorphisms and menopausal status: the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2008;200(2):322-8.
Alam AB, Lutsey PL, Gottesman RF, Tin A, Alonso A. "Low Serum Magnesium is Associated with Incident Dementia in the ARIC-NCS Cohort." Nutrients. 2020;12(10).
Folsom AR, Ma J, Eckfeldt JH, Nieto FJ, Metcalf PA, Barnes RW. "Low serum albumin. Association with diabetes mellitus and other cardiovascular risk factors but not with prevalent cardiovascular disease or carotid artery intima-media thickness. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Ann Epidemiol. 1995;5(3):186-91.
Folsom AR, Ohira T, Yamagishi K, Cushman M. "Low protein C and incidence of ischemic stroke and coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study." J Thromb Haemost. 2009;7(11):1774-8.
Liao F, Folsom AR, Brancati FL. "Is low magnesium concentration a risk factor for coronary heart disease? The Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 1998;136(3):480-90.
Lu Y, Pike JR, Selvin E, et al. "Low Liver Enzymes and Risk of Dementia: The Atherosclerosis Risk in Communities (ARIC) Study." J Alzheimers Dis. 2021;79(4):1775-1784.
Aggarwal V, Schneider ALC, Selvin E. "Low hemoglobin A(1c) in nondiabetic adults: an elevated risk state?" Diabetes Care. 2012;35(10):2055-60.
Dekker JM, Crow RS, Folsom AR, et al. "Low heart rate variability in a 2-minute rhythm strip predicts risk of coronary heart disease and mortality from several causes: the ARIC Study. Atherosclerosis Risk In Communities." Circulation. 2000;102(11):1239-44.
Maheshwari A, Norby FL, Soliman EZ, Adabag S, Whitsel EA, Alonso A. "Low Heart Rate Variability in a 2-Minute Electrocardiogram Recording Is Associated with an Increased Risk of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities Study." PLoS One. 2016;11(8):e0161648.
Franceschini N, Muallem H, Rose KM, Boerwinkle E, Maeda N. "Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2009;7(3):496-8.
Liew G, Wang J J, Duncan BB, et al. "Low birthweight is associated with narrower arterioles in adults." Hypertension. 2008;51(4):933-8.
Pellanda LC, Duncan BB, Vigo A, Rose K, Folsom AR, Erlinger TP. "Low birth weight and markers of inflammation and endothelial activation in adulthood: the ARIC study." Int J Cardiol. 2009;134(3):371-7.
Yu B, Li AH, Metcalf GA, et al. "Loss-of-function variants influence the human serum metabolome." Sci Adv. 2016;2(8):e1600800.
Crosby J, Peloso GM, Auer PL, et al. "Loss-of-function mutations in APOC3, triglycerides, and coronary disease." N Engl J Med. 2014;371(1):22-31.
Bainbridge MN, Davis EE, Choi W-Y, et al. "Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction." Circ Cardiovasc Genet. 2015;8(4):544-52.
Tin A, Scharpf R, Estrella MM, et al. "The Loss of Associates with Kidney Failure and Heart Failure." J Am Soc Nephrol. 2017;28(11):3345-3352.
Olson KA, Viera AJ, Soliman EZ, Crow RS, Rosamond WD. "Long-term prognosis associated with J-point elevation in a large middle-aged biracial cohort: the ARIC study." Eur Heart J. 2011;32(24):3098-106.
Yano Y, Griswold M, Wang W, et al. "Long-Term Blood Pressure Level and Variability From Midlife to Later Life and Subsequent Cognitive Change: The ARIC Neurocognitive Study." J Am Heart Assoc. 2018;7(15):e009578.
Lutsey PL, B Windham G, Misialek JR, Cushman M, Kucharska-Newton AMaria, Basu S. "Long-Term Association of Venous Thromboembolism With Frailty, Physical Functioning, and Quality of Life: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2020;9(12):e015656.
Avery CL, Mills KT, Chambless LE, et al. "Long-term association between self-reported signs and symptoms and heart failure hospitalizations: the Atherosclerosis Risk In Communities (ARIC) Study." Eur J Heart Fail. 2010;12(3):232-8.
Petruski-Ivleva N, Viera AJ, Shimbo D, et al. "Longitudinal Patterns of Change in Systolic Blood Pressure and Incidence of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." Hypertension. 2016;67(6):1150-6.
Harding BN, Norby FL, Heckbert SR, et al. "Longitudinal Measures of Blood Pressure and Subclinical Atrial Arrhythmias: The MESA and the ARIC Study." J Am Heart Assoc. 2021;10(11):e020260.
Folsom AR, Lutsey PL, Heckbert SR, et al. "Longitudinal increases in blood biomarkers of inflammation or cardiovascular disease and the incidence of venous thromboembolism." J Thromb Haemost. 2018;16(10):1964-1972.
Monda KL, Ballantyne CM, North KE. "Longitudinal impact of physical activity on lipid profiles in middle-aged adults: the Atherosclerosis Risk in Communities Study." J Lipid Res. 2009;50(8):1685-91.
Silva GE, An M-W, Goodwin JL, et al. "Longitudinal evaluation of sleep-disordered breathing and sleep symptoms with change in quality of life: the Sleep Heart Health Study (SHHS)." Sleep. 2009;32(8):1049-57.
Nettleton JA, Volcik KA, Demerath EW, Boerwinkle E, Folsom AR. "Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study." Ann Epidemiol. 2008;18(11):842-6.
Keshawarz A, Joehanes R, Guan W, et al. "Longitudinal change in blood DNA epigenetic signature after smoking cessation." Epigenetics. 2021:1-12.
Ting J, Jiang K, Du S, et al. "Longitudinal Blood Pressure Patterns from Mid-to-Late Life and Late-life Hearing Loss in the Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2021.
Metcalf PA, Meyer ML, Tanaka H, et al. "Longitudinal associations of blood pressure with aortic stiffness and pulsatility: the Atherosclerosis Risk in Communities Study." J Hypertens. 2021;39(5):987-993.
Wang SY, Tan ASL, Claggett B, et al. "Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(12):1203-1212.
Lamichhane AP, Couper DJ, Jenkins GP. "Longitudinal Associations Between Body Mass Index During Young Adulthood, Subsequent Weight Change, and Incident Diabetes During Mid- and Older-Adulthood in Non-Hispanic White and African American Populations: The Atherosclerosis Risk in Communities Study." Metab Syndr Relat Disord. 2020;18(7):313-320.
Mondul AM, Joshu CE, Barber JR, et al. "Longer-term Lipid-lowering Drug Use and Risk of Incident and Fatal Prostate Cancer in Black and White Men in the ARIC Study." Cancer Prev Res (Phila). 2018;11(12):779-788.
Lutsey PL, Cushman M, Heckbert SR, Tang W, Folsom AR. "Longer legs are associated with greater risk of incident venous thromboembolism independent of total body height. The Longitudinal Study of Thromboembolism Etiology (LITE)." Thromb Haemost. 2011;106(1):113-20.
Imamura F, Lemaitre RN, King IB, et al. "Long-chain monounsaturated Fatty acids and incidence of congestive heart failure in 2 prospective cohorts." Circulation. 2013;127(14):1512-21, 1521e1-18.
Stevens J, Erber E, Truesdale KP, Wang C-H, Cai J. "Long- and short-term weight change and incident coronary heart disease and ischemic stroke: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2013;178(2):239-48.
Kucharska-Newton A, Matsushita K, Mok Y, et al. "Loneliness and its predictors among older adults prior to and during the COVID-19 pandemic: cross-sectional and longitudinal survey findings from participants of the Atherosclerosis Risk in Communities (ARIC) Study cohort in the USA." BMJ Open. 2021;11(12):e053542.
Ganesh SK, Tragante V, Guo W, et al. "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.
"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Schneider ALC, Lazo M, Ndumele CE, et al. "Liver enzymes, race, gender and diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study." Diabet Med. 2013;30(8):926-33.
Ruban A, Daya N, Schneider ALC, et al. "Liver Enzymes and Risk of Stroke: The Atherosclerosis Risk in Communities (ARIC) Study." J Stroke. 2020;22(3):357-368.
Ballantyne CM, Hoogeveen RC, Bang H, et al. "Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study." Arch Intern Med. 2005;165(21):2479-84.
Ballantyne CM, Hoogeveen RC, Bang H, et al. "Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2004;109(7):837-42.
Folsom AR, Lutsey PL, Roetker NS, Ballantyne CM, Hoogeveen RC, Rosamond WD. "Lipoprotein-associated phospholipase A2 and venous thromboembolism: a prospective study." Thromb Res. 2013;132(1):44-6.
Nambi V, Hoogeveen RC, Chambless L, et al. "Lipoprotein-associated phospholipase A2 and high-sensitivity C-reactive protein improve the stratification of ischemic stroke risk in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2009;40(2):376-81.
Garg PK, Norby FL, Polfus LM, et al. "Lipoprotein-associated phospholipase A and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC)." Atherosclerosis. 2018;268:12-18.
Saeed A, Sun W, Agarwala A, et al. "Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
Schreiner PJ. "Lipoprotein(a) as a risk factor for preclinical atherosclerotic disease in a biracial cohort: the Atherosclerosis Risk in Communities (ARIC) Study." Chem Phys Lipids. 1994;67-68:405-10.
Schreiner PJ, Morrisett JD, Sharrett AR, et al. "Lipoprotein[a] as a risk factor for preclinical atherosclerosis." Arterioscler Thromb. 1993;13(6):826-33.
Schreiner PJ, Chambless LE, Brown SA, Watson RL, Toole J, Heiss G. "Lipoprotein(a) as a correlate of stroke and transient ischemic attack prevalence in a biracial cohort: the ARIC Study. Atherosclerosis Risk in Communities." Ann Epidemiol. 1994;4(5):351-9.
Obisesan OH, Kou M, Wang FM, et al. "Lipoprotein(a) and Subclinical Vascular and Valvular Calcification on Cardiac Computed Tomography: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(11):e024870.
Iso H, Koike KA, Folsom AR, et al. "Lipoprotein(a) and its correlates in Japanese and U.S. population samples." Ann Epidemiol. 1996;6(4):324-30.
Ohira T, Schreiner PJ, Morrisett JD, Chambless LE, Rosamond WD, Folsom AR. "Lipoprotein(a) and incident ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2006;37(6):1407-12.
Mehta A, Virani SS, Ayers CR, et al. "Lipoprotein(a) and Family History Predict Cardiovascular Disease Risk." J Am Coll Cardiol. 2020;76(7):781-793.
Kubota Y, Folsom AR, Ballantyne CM. "Lipoprotein(a) and abdominal aortic aneurysm risk: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2018;268:63-67.
Ma Y, Tucker KL, Smith CE, et al. "Lipoprotein lipase variants interact with polyunsaturated fatty acids for obesity traits in women: replication in two populations." Nutr Metab Cardiovasc Dis. 2014;24(12):1323-9.
Pokharel Y, Sun W, Polfus LM, et al. "Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study." Atherosclerosis. 2015;241(2):641-8.
Rodriguez S, Gaunt TR, Guo Y, et al. "Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array." Eur J Hum Genet. 2016;24(1):106-12.
Kitzmiller JP, Foraker RE, Rose KM. "Lipid-lowering pharmacotherapy and socioeconomic status: Atherosclerosis Risk In Communities (ARIC) surveillance study." BMC Public Health. 2013;13:488.
Marrone MT, Mondul AM, Prizment AE, et al. "Lipid-Lowering Drug Use and Cancer Incidence and Mortality in the ARIC Study." JNCI Cancer Spectr. 2021;5(5).
Simino J, Kume R, Kraja AT, et al. "Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program." Atherosclerosis. 2014;235(1):84-93.
Barral S, Cheng R, Reitz C, et al. "Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease." Alzheimers Dement. 2015;11(12):1397-1406.
Bell EJ, Lutsey PL, Basu S, Cushman M, Heckbert SR, Lloyd-Jones DM. "Lifetime Risk of Venous Thromboembolism in Two Cohort Studies." Am J Med. 2016;129(3):339.e19-26.
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
Mou L, Norby FL, Chen LYee, et al. "Lifetime Risk of Atrial Fibrillation by Race and Socioeconomic Status: ARIC Study (Atherosclerosis Risk in Communities)." Circ Arrhythm Electrophysiol. 2018;11(7):e006350.
Tang W, Yao L, Roetker NS, et al. "Lifetime Risk and Risk Factors for Abdominal Aortic Aneurysm in a 24-Year Prospective Study: The ARIC Study (Atherosclerosis Risk in Communities)." Arterioscler Thromb Vasc Biol. 2016;36(12):2468-2477.
Carson A P, Carson A PL, Rose KM, et al. "Lifetime prevalence of migraine and other headaches lasting 4 or more hours: the Atherosclerosis Risk in Communities (ARIC) study." Headache. 2004;44(1):20-8.
Xu H, Schwander K, Brown MR, et al. "Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions." Eur J Hum Genet. 2021;29(5):839-850.
Evans CR, Hong C-P, Folsom AR, et al. "Lifestyle Moderates Genetic Risk of Venous Thromboembolism: The ARIC Study." Arterioscler Thromb Vasc Biol. 2020;40(11):2756-2763.
Krishnappa D, Wang W, Rooney MR, et al. "Life's Simple 7 cardiovascular health score and premature atrial contractions: The atherosclerosis risk in communities (ARIC) study." Int J Cardiol. 2021.
Commodore-Mensah Y, Mok Y, Gottesman RF, et al. "Life's Simple 7 at Midlife and Risk of Recurrent Cardiovascular Disease and Mortality after Stroke: The ARIC study." J Stroke Cerebrovasc Dis. 2022;31(7):106486.
Garg PK, O'Neal WT, Mok Y, Heiss G, Coresh JJ. "Life's Simple 7 and Peripheral Artery Disease Risk: The Atherosclerosis Risk in Communities Study." Am J Prev Med. 2018;55(5):642-649.
Xiao Q, Heiss G, Kucharska-Newton A, Bey G, Love S-AM, Whitsel EA. "Life-Course Neighborhood Socioeconomic Status and Cardiovascular Events in Black and White Adults in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2022;191(8):1470-1484.
George KM, Lutsey PL, Kucharska-Newton AMaria, Palta P, Heiss G, Osypuk T. "Life-Course Individual and Neighborhood Socioeconomic Status and Risk of Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." Am J Epidemiol. 2020;189(10):1134-1142.
Power MC, Schneider ALC, Wruck L, et al. "Life-course blood pressure in relation to brain volumes." Alzheimers Dement. 2016;12(8):890-9.
Chichlowska KL, Rose KM, Diez-Roux AV, Golden SH, McNeill AM, Heiss G. "Life course socioeconomic conditions and metabolic syndrome in adults: the Atherosclerosis Risk in Communities (ARIC) Study." Ann Epidemiol. 2009;19(12):875-83.
He KY, Li X, Kelly TN, et al. "Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data." Hum Genet. 2019;138(2):199-210.
Claussnitzer M, Dankel SN, Klocke B, et al. "Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms." Cell. 2014;156(1-2):343-58.
Andriankaja OM, Barros SP, Moss K, et al. "Levels of serum interleukin (IL)-6 and gingival crevicular fluid of IL-1beta and prostaglandin E(2) among non-smoking subjects with gingivitis and type 2 diabetes." J Periodontol. 2009;80(2):307-16.

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