ARIC Publications
"Genetic studies of body mass index yield new insights for obesity biology." Nature. 2015;518(7538):197-206.
"Genetic susceptibility, obesity and lifetime risk of type 2 diabetes: The ARIC study and Rotterdam Study." Diabet Med. 2021;38(10):e14639.
"The genetic underpinnings of variation in ages at menarche and natural menopause among women from the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) Study: A trans-ethnic meta-analysis." PLoS One. 2018;13(7):e0200486.
"Genetic variability of smoking persistence in African Americans." Cancer Prev Res (Phila). 2011;4(5):729-34.
"A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study." Eur Heart J. 2009;30(10):1222-8.
"Genetic Variants Associated with Circulating Fibroblast Growth Factor 23." J Am Soc Nephrol. 2018;29(10):2583-2592.
"Genetic Variants Associated with Circulating Parathyroid Hormone." J Am Soc Nephrol. 2017;28(5):1553-1565.
"Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study." BMC Med Genet. 2013;14:98.
"Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study." Am J Med Genet B Neuropsychiatr Genet. 2017;174(3):269-282.
"Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study." Am J Epidemiol. 2010;171(1):14-23.
"Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections." Am J Hum Genet. 2016;99(3):762-769.
"Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population." Hum Genet. 2018;137(1):85-94.
"Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk." Nature. 2011;478(7367):103-9.
"Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk." J Am Coll Cardiol. 2018;72(15):1763-1773.
"Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the Atherosclerosis Risk in Communities MRI Study." Hum Genet. 2011;129(6):655-62.
"Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk." Atherosclerosis. 2015;241(2):419-26.
"Genetic variation and decreased risk for obesity in the Atherosclerosis Risk in Communities Study." Diabetes Obes Metab. 2007;9(4):548-57.
"Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study." PLoS One. 2013;8(2):e55258.
"Genetic variation associated with circulating monocyte count in the eMERGE Network." Hum Mol Genet. 2013;22(10):2119-27.
"Genetic variation at 16q24.2 is associated with small vessel stroke." Ann Neurol. 2017;81(3):383-394.
"Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project." Dement Geriatr Cogn Disord. 2018;45(1-2):1-17.
"Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study." Hum Mol Genet. 2006;15(10):1640-9.
"Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study." BMC Med Genet. 2011;12:16.
"Genetic variation of the renin-angiotensin system and chronic kidney disease progression in black individuals in the atherosclerosis risk in communities study." J Am Soc Nephrol. 2006;17(2):504-12.
"Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations." Circulation. 2009;119(7):940-51.
"Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality." Eur Heart J. 2021;42(18):1742-1756.
"The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals." Nat Genet. 2016;48(10):1171-1184.
"Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study." Front Genet. 2019;10:494.
"Genetics of Obesity in Diverse Populations." Curr Diab Rep. 2018;18(12):145.
"Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study." PLoS One. 2015;10(6):e0128452.
"Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease." PLoS One. 2014;9(6):e94661.
"Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders." Am J Hum Genet. 2018;103(5):691-706.
"Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation." Nat Commun. 2018;9(1):4455.
"Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data." Nat Commun. 2019;10(1):2773.
"A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance." Nat Genet. 2012;44(6):659-69.
"Genome-wide association analyses identify 18 new loci associated with serum urate concentrations." Nat Genet. 2013;45(2):145-54.
"Genome-wide association analysis identifies multiple loci related to resting heart rate." Hum Mol Genet. 2010;19(19):3885-94.
"Genome-wide association analysis identifies six new loci associated with forced vital capacity." Nat Genet. 2014;46(7):669-77.
"Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations." Am J Hum Genet. 2013;93(3):545-54.
"Genome-wide association analysis of incident coronary heart disease (CHD) in African Americans: a short report." PLoS Genet. 2011;7(8):e1002199.
"Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network." Hum Mol Genet. 2013;22(12):2529-38.
"Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans." Mol Neurobiol. 2017;54(10):8021-8032.
"Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2." Stroke. 2016;47(2):307-16.
"Genome-wide association and functional follow-up reveals new loci for kidney function." PLoS Genet. 2012;8(3):e1002584.
"Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function." Nat Genet. 2011;43(11):1082-90.
"Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure." Nat Commun. 2020;11(1):163.
"Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria." Nat Commun. 2019;10(1):4130.
"Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits." Eur J Hum Genet. 2019;27(6):952-962.
"Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium." PLoS One. 2018;13(5):e0196951.
"Genome-wide association meta-analysis of fish and EPA+DHA consumption in 17 US and European cohorts." PLoS One. 2017;12(12):e0186456.
"Genome-wide association of body fat distribution in African ancestry populations suggests new loci." PLoS Genet. 2013;9(8):e1003681.
"Genome-Wide Association of Copy Number Polymorphisms and Kidney Function." PLoS One. 2017;12(1):e0170815.
"Genome-Wide Association of Kidney Traits in Hispanics/Latinos Using Dense Imputed Whole-Genome Sequencing Data: The Hispanic Community Health Study/Study of Latinos." Circ Genom Precis Med. 2020;13(4):e002891.
"Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging." Genome Biol. 2021;22(1):194.
"Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes." Diabetes. 2016;65(3):803-17.
"Genome-wide association studies identify genetic loci for low von Willebrand factor levels." Eur J Hum Genet. 2016;24(7):1035-40.
"Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium." Ann Neurol. 2011;69(6):928-39.
"Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels." PLoS Genet. 2010;6(8).
"Genomewide association studies of stroke." N Engl J Med. 2009;360(17):1718-28.
"Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy." Sci Rep. 2018;8(1):5675.
"A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos." Am J Hum Genet. 2020;107(5):849-863.
"Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation." Blood. 2012;120(24):4873-81.
"Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2." Arterioscler Thromb Vasc Biol. 2014;34(5):1093-101.
"Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium." PLoS One. 2016;11(3):e0144997.
"Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies." BMC Med Genet. 2008;9:49.
"Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele." Hum Mol Genet. 2011;20(20):4056-68.
"A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium." Genet Epidemiol. 2013;37(5):512-521.
"Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin." Hum Genet. 2013;132(6):619-27.
"Genome-wide association study identifies common loci influencing circulating glycated hemoglobin (HbA1c) levels in non-diabetic subjects: the Long Life Family Study (LLFS)." Metabolism. 2014;63(4):461-8.
"Genome-wide association study identifies GPC5 as a novel genetic locus protective against sudden cardiac arrest." PLoS One. 2010;5(3):e9879.
"A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology." Blood. 2019;133(9):967-977.
"Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu." Circ Cardiovasc Genet. 2013;6(2):171-83.
"Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study." Blood. 2010;116(23):5032-6.
"Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans." Hum Genomics. 2019;13(1):21.
"Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure." Nat Genet. 2011;43(10):1005-11.
"Genome-wide association study identifies three novel loci for type 2 diabetes." Hum Mol Genet. 2014;23(1):239-46.
"Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels." Nat Commun. 2018;9(1):260.