ARIC Publications
Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals." Hum Mol Genet. 2013;22(1):184-201.
"Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci." Am J Hum Genet. 2014;94(3):349-60.
"Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci." Mol Psychiatry. 2020.
"Gene-environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities study." Int J Obes (Lond). 2007;31(6):919-26.
"Gene-gene Interaction Analyses for Atrial Fibrillation." Sci Rep. 2016;6:35371.
"Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate." Brain. 2022;145(6):1992-2007.
"A general framework for integrative analysis of incomplete multiomics data." Genet Epidemiol. 2020;44(7):646-664.
"Generalizability of findings from a clinical sample to a community-based sample: A comparison of ADNI and ARIC." Alzheimers Dement. 2021.
"Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study." PLoS Biol. 2013;11(9):e1001661.
"Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations." Int J Obes (Lond). 2017;41(2):324-331.
"Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study." Am J Hematol. 2018.
"Generalized estimating equations for genome-wide association studies using longitudinal phenotype data." Stat Med. 2015;34(1):118-30.
"Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data." J Biomed Inform. 2016;60:114-9.
"Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease." Neuron. 2015;88(3):499-513.
"Genetic analyses of diverse populations improves discovery for complex traits." Nature. 2019;570(7762):514-518.
"Genetic analysis of a population heavy drinking phenotype identifies risk variants in whites." J Clin Psychopharmacol. 2013;33(2):206-10.
"Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits." Nat Genet. 2018;50(10):1412-1425.
"Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting." Neurology. 2019.
"Genetic architecture of subcortical brain structures in 38,851 individuals." Nat Genet. 2019;51(11):1624-1636.
"The genetic architecture of the human cerebral cortex." Science. 2020;367(6484).
"A genetic association study of activated partial thromboplastin time in European Americans and African Americans: the ARIC Study." Hum Mol Genet. 2015;24(8):2401-8.
"A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups." Thromb Res. 2014;134(2):462-7.
"Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization." Nat Genet. 2014;46(8):826-36.
"Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function." Nat Commun. 2016;7:10023.
"Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease." Am J Hum Genet. 2012;91(1):152-62.
"The Genetic Contribution of West-African Ancestry to Protection against Central Obesity in African-American Men but Not Women: Results from the ARIC and MESA Studies." Front Genet. 2016;7:89.
"Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949)." Mol Psychiatry. 2015;20(2):183-92.
"Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults." Nat Commun. 2020;11(1):4796.
"Genetic determinants influencing human serum metabolome among African Americans." PLoS Genet. 2014;10(3):e1004212.
"Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation." Circ Genom Precis Med. 2020;13(5):387-395.
"Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort." Blood. 2011;117(19):5224-30.
"Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed." Cell Genom. 2022;2(1).
"Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium." Atherosclerosis. 2012;222(1):138-47.
"Genetic diversity is a predictor of mortality in humans." BMC Genet. 2014;15:159.
"Genetic evidence for a normal-weight "metabolically obese" phenotype linking insulin resistance, hypertension, coronary artery disease, and type 2 diabetes." Diabetes. 2014;63(12):4369-77.
"Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci." Nat Genet. 2015;47(12):1415-25.
"Genetic insights into biological mechanisms governing human ovarian ageing." Nature. 2021;596(7872):393-397.
"Genetic invalidation of Lp-PLA as a therapeutic target: Large-scale study of five functional Lp-PLA-lowering alleles." Eur J Prev Cardiol. 2017;24(5):492-504.
"Genetic Investigation Into the Differential Risk of Atrial Fibrillation Among Black and White Individuals." JAMA Cardiol. 2016;1(4):442-50.
"Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations." Nat Genet. 2019;51(3):494-505.
"Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies." Kidney Int. 2022;102(3):624-639.
"Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis." Nat Genet. 2017;49(3):426-432.
"Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies." Am Heart J. 2016;175:112-20.
"Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium." PLoS Genet. 2011;7(7):e1002193.
"Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium." PLoS One. 2020;15(11):e0230035.
"Genetic loci for retinal arteriolar microcirculation." PLoS One. 2013;8(6):e65804.
"Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study." BMC Genet. 2015;16:56.
"Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) study." Genet Epidemiol. 2014;38(8):709-13.
"Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing." Nat Genet. 2019;51(3):414-430.
"Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization." Circulation. 2017;135(8):741-754.
"Genetic overlap between diagnostic subtypes of ischemic stroke." Stroke. 2015;46(3):615-9.
"Genetic predisposition to higher blood pressure increases coronary artery disease risk." Hypertension. 2013;61(5):995-1001.
"Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease." N Engl J Med. 2016;375(24):2349-2358.
"Genetic risk factors for BMI and obesity in an ethnically diverse population: results from the population architecture using genomics and epidemiology (PAGE) study." Obesity (Silver Spring). 2013;21(4):835-46.
"Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies." Lancet Neurol. 2012;11(11):951-62.
"Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study." Neurology. 2022.
"A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies." Atherosclerosis. 2012;223(2):421-6.
"A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations." J Clin Endocrinol Metab. 2015;100(5):E799-807.
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