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ARIC Publications

2017
Fernández-Rhodes L, Gong J, Haessler J, et al. "Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci." Hum Genet. 2017;136(6):771-800.
Bien SA, Pankow JS, Haessler J, et al. "Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium." Diabetologia. 2017;60(12):2384-2398.
Rusu V, Hoch E, Mercader JM, et al. "Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms." Cell. 2017;170(1):199-212.e20.
McMahon GM, Hwang S-J, Clish CB, et al. "Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease." Kidney Int. 2017;91(6):1426-1435.
Soliman EZ, Zhang Z-M, Chen LYee, Tereshchenko LG, Arking D. "Usefulness of Maintaining a Normal Electrocardiogram Over Time for Predicting Cardiovascular Health." Am J Cardiol. 2017;119(2):249-255.
Millen AE, Nie J, Sahli MW, et al. "Vitamin D Status and Prevalent Early Age-Related Macular Degeneration in African Americans and Caucasians: The Atherosclerosis Risk in Communities (ARIC) Study." J Nutr Health Aging. 2017;21(7):772-780.
Simino J, Wang Z, Bressler J, et al. "Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study." PLoS One. 2017;12(7):e0180046.
de Vries PS, Yu B, Feofanova EV, et al. "Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study." Hum Mol Genet. 2017;26(17):3442-3450.
Kubota Y, Alonso A. "β-Thromboglobulin and incident cardiovascular disease risk: The Atherosclerosis Risk in Communities study." Thromb Res. 2017;155:116-120.
2016
Michos ED, Selvin E, Misialek JR, et al. "25-Hydroxyvitamin D Levels and Markers of Subclinical Myocardial Damage and Wall Stress: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2016;5(11).
van der Harst P, van Setten J, Verweij N, et al. "52 Genetic Loci Influencing Myocardial Mass." J Am Coll Cardiol. 2016;68(13):1435-1448.
Millen AE, Sahli MW, Nie J, et al. "Adequate vitamin D status is associated with the reduced odds of prevalent diabetic retinopathy in African Americans and Caucasians." Cardiovasc Diabetol. 2016;15(1):128.
Shakiba M, Soori H, Mansournia MAli, Nazari SSaeed Hash. "Adjusting for reverse causation to estimate the effect of obesity on mortality after incident heart failure in the Atherosclerosis Risk in Communities (ARIC) study." Epidemiol Health. 2016;38:e2016025.
O'Neal WT, Kamel H, Zhang Z-M, Chen LYee, Alonso A. "Advanced interatrial block and ischemic stroke: The Atherosclerosis Risk in Communities Study." Neurology. 2016;87(4):352-6.
Lazo M, Chen Y, McEvoy JW, et al. "Alcohol Consumption and Cardiac Biomarkers: The Atherosclerosis Risk in Communities (ARIC) Study." Clin Chem. 2016;62(9):1202-10.
Hua S, Loehr LR, Tanaka H, Heiss G, Coresh JJ, Selvin E. "Ankle-brachial index and incident diabetes mellitus: the atherosclerosis risk in communities (ARIC) study." Cardiovasc Diabetol. 2016;15(1):163.
"Are There Clinical Implications of Racial Differences in HbA1c? A Difference, to Be a Difference, Must Make a Difference." Diabetes Care. 2016;39(8):1462-7.
Gottesman RF, Schneider ALC, Zhou Y, et al. "The ARIC-PET amyloid imaging study: Brain amyloid differences by age, race, sex, and APOE." Neurology. 2016;87(5):473-80.
Marioni RE, Yang J, Dykiert D, et al. "Assessing the genetic overlap between BMI and cognitive function." Mol Psychiatry. 2016;21(10):1477-82.
Rosenthal EA, Makaryan V, Burt AA, et al. "Association Between Absolute Neutrophil Count and Variation at TCIRG1: The NHLBI Exome Sequencing Project." Genet Epidemiol. 2016;40(6):470-4.
Srinath R, Gottesman RF, Golden SHill, Carson KA. "Association Between Endogenous Testosterone and Cerebrovascular Disease in the ARIC Study (Atherosclerosis Risk in Communities)." Stroke. 2016;47(11):2682-2688.
Tin A, Grams ME, Ashar FN, et al. "Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study." J Am Soc Nephrol. 2016;27(8):2467-73.
Selvin E, Rawlings A, Lutsey PL, Maruthur N, Pankow JS, Steffes M. "Association of 1,5-Anhydroglucitol With Cardiovascular Disease and Mortality." Diabetes. 2016;65(1):201-8.
Liang M, McEvoy JWilliam, Chen Y, Sharrett ARichey. "Association of a Biomarker of Glucose Peaks, 1,5-Anhydroglucitol, With Subclinical Cardiovascular Disease." Diabetes Care. 2016;39(10):1752-9.
Appiah D, Schreiner PJ, Demerath EW, Loehr LR, Chang PP. "Association of Age at Menopause With Incident Heart Failure: A Prospective Cohort Study and Meta-Analysis." J Am Heart Assoc. 2016;5(8).
Peloso GM, Lange LA, Varga TV, et al. "Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study." Circ Cardiovasc Genet. 2016;9(4):368-74.
Norby FL, Eryd SAdamsson, Niemeijer MN, et al. "Association of Lipid-Related Genetic Variants with the Incidence of Atrial Fibrillation: The AFGen Consortium." PLoS One. 2016;11(3):e0151932.
Mirzaa GM, Campbell CD, Solovieff N, et al. "Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism." JAMA Neurol. 2016;73(7):836-845.
Colantonio LD, Bittner V, Reynolds K, et al. "Association of Serum Lipids and Coronary Heart Disease in Contemporary Observational Studies." Circulation. 2016;133(3):256-64.
Song J, Xue C, Preisser JS, et al. "Association of Single Nucleotide Polymorphisms in the ST3GAL4 Gene with VWF Antigen and Factor VIII Activity." PLoS One. 2016;11(9):e0160757.
Kwon Y, Norby FL, Jensen PN, et al. "Association of Smoking, Alcohol, and Obesity with Cardiovascular Death and Ischemic Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study and Cardiovascular Health Study (CHS)." PLoS One. 2016;11(1):e0147065.
Fretz A, Schneider ALC, McEvoy JW, Hoogeveen RC, Ballantyne CM, Coresh JJ. "The Association of Socioeconomic Status With Subclinical Myocardial Damage, Incident Cardiovascular Events, and Mortality in the ARIC Study." Am J Epidemiol. 2016;183(5):452-61.
Willems SM, Cornes BK, Brody JA, et al. "Association of the IGF1 gene with fasting insulin levels." Eur J Hum Genet. 2016;24(9):1337-43.
Seaman CD, George KM, Ragni M. "Association of von Willebrand factor deficiency with prevalent cardiovascular disease and asymptomatic carotid atherosclerosis: The Atherosclerosis Risk in Communities Study." Thromb Res. 2016;144:236-8.
Bello NA, Cheng S, Claggett B, et al. "Association of Weight and Body Composition on Cardiac Structure and Function in the ARIC Study (Atherosclerosis Risk in Communities)." Circ Heart Fail. 2016;9(8).
Yu B, Heiss G, Alexander D, Grams ME. "Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 2016;183(7):650-6.
Agarwala A, Virani S, Couper DJ, et al. "Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study." Atherosclerosis. 2016;253:156-163.
Rebholz CM, Grams ME, Lutsey PL, et al. "Biomarkers of Vitamin D Status and Risk of ESRD." Am J Kidney Dis. 2016;67(2):235-42.
Cushman M, O'Meara ES, Heckbert SR, Zakai NA, Rosamond WD. "Body size measures, hemostatic and inflammatory markers and risk of venous thrombosis: The Longitudinal Investigation of Thromboembolism Etiology." Thromb Res. 2016;144:127-32.
Di Angelantonio E, Bhupathiraju S, Wormser D, et al. "Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents." Lancet. 2016;388(10046):776-86.
Zhang Z-M, Rautaharju PM, Prineas RJ, Loehr LR, Rosamond WD. "Bundle branch blocks and the risk of mortality in the Atherosclerosis Risk in Communities study." J Cardiovasc Med (Hagerstown). 2016;17(6):411-7.
Luft VC, Duncan BB, Schmidt MI, et al. "Carboxymethyl lysine, an advanced glycation end product, and incident diabetes: a case-cohort analysis of the ARIC Study." Diabet Med. 2016;33(10):1392-8.
Hegde SM, Gonçalves A, Claggett B, et al. "Cardiac structure and function and leisure-time physical activity in the elderly: The Atherosclerosis Risk in Communities Study." Eur Heart J. 2016;37(32):2544-51.
Stevens J, Erber-Oakkar E, Cui Z, Cai J, Virani SS, Di Angelantonio E. "Cardiovascular disease risk by assigned treatment using the 2013 and 1998 obesity guidelines." Obesity (Silver Spring). 2016;24(7):1554-60.
Wong ND, Zhao Y, Patel R, et al. "Cardiovascular Risk Factor Targets and Cardiovascular Disease Event Risk in Diabetes: A Pooling Project of the Atherosclerosis Risk in Communities Study, Multi-Ethnic Study of Atherosclerosis, and Jackson Heart Study." Diabetes Care. 2016;39(5):668-76.
Bekwelem W, Jensen PN, Norby FL, et al. "Carotid Atherosclerosis and Stroke in Atrial Fibrillation: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(6):1643-6.
Chen LYee, Leening MJG, Norby FL, et al. "Carotid Intima-Media Thickness and Arterial Stiffness and the Risk of Atrial Fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study, Multi-Ethnic Study of Atherosclerosis (MESA), and the Rotterdam Study." J Am Heart Assoc. 2016;5(5).
Pang Y, Sang Y, Ballew SH, Grams ME, Heiss G, Coresh JJ. "Carotid Intima-Media Thickness and Incident ESRD: The Atherosclerosis Risk in Communities (ARIC) Study." Clin J Am Soc Nephrol. 2016;11(7):1197-205.
Yazdani A, Yazdani A, Saniei A. "A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels." Metabolomics. 2016;12:104.
Yazdani A, Yazdani A. "A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate." OMICS. 2016;20(8):480-4.
Vu KN, Ballantyne CM, Hoogeveen RC, Nambi V, Volcik KA, Boerwinkle E. "Causal Role of Alcohol Consumption in an Improved Lipid Profile: The Atherosclerosis Risk in Communities (ARIC) Study." PLoS One. 2016;11(2):e0148765.
Cobb LK, McAdams-Demarco MA, Gudzune KA, et al. "Changes in Body Mass Index and Obesity Risk in Married Couples Over 25 Years: The ARIC Cohort Study." Am J Epidemiol. 2016;183(5):435-43.
Ishigami J, Grams ME, Naik RP, Coresh JJ. "Chronic Kidney Disease and Risk for Gastrointestinal Bleeding in the Community: The Atherosclerosis Risk in Communities (ARIC) Study." Clin J Am Soc Nephrol. 2016;11(10):1735-1743.
Prizment AE, Linabery AM, Lutsey PL, et al. "Circulating Beta-2 Microglobulin and Risk of Cancer: The Atherosclerosis Risk in Communities Study (ARIC)." Cancer Epidemiol Biomarkers Prev. 2016;25(4):657-64.
Winkler TW, Justice AE, Graff M, et al. "Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2016;12(6):e1006166.
Meyer ML, Tanaka H, Palta P, Cheng S, Gouskova N, Aguilar D. "Correlates of Segmental Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(1):114-22.
van der Laan SW, Fall T, Soumaré A, et al. "Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study." J Am Coll Cardiol. 2016;68(9):934-45.
Rebholz CM, Crews DC, Grams ME, et al. "DASH (Dietary Approaches to Stop Hypertension) Diet and Risk of Subsequent Kidney Disease." Am J Kidney Dis. 2016;68(6):853-861.
Liu X, Wu C, Li C. "dbNSFP v3.0: A One-Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice-Site SNVs." Hum Mutat. 2016;37(3):235-41.
Rubin J, Matsushita K, Lazo M, et al. "Determinants of minimal elevation in high-sensitivity cardiac troponin T in the general population." Clin Biochem. 2016;49(9):657-662.
Deo R, Norby FL, Katz R, et al. "Development and Validation of a Sudden Cardiac Death Prediction Model for the General Population." Circulation. 2016;134(11):806-16.
Fox ER, Samdarshi TE, Musani SK, et al. "Development and Validation of Risk Prediction Models for Cardiovascular Events in Black Adults: The Jackson Heart Study Cohort." JAMA Cardiol. 2016;1(1):15-25.
Schneider ALC, Kalyani RR, Golden S, et al. "Diabetes and Prediabetes and Risk of Hospitalization: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):772-9.
Bell EJ, Folsom AR, Lutsey PL, Selvin E, Zakai NA, Cushman M. "Diabetes mellitus and venous thromboembolism: A systematic review and meta-analysis." Diabetes Res Clin Pract. 2016;111:10-8.
Khera AV, Won H-H, Peloso GM, et al. "Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia." J Am Coll Cardiol. 2016;67(22):2578-89.
McEvoy JW, Chen Y, Rawlings A, et al. "Diastolic Blood Pressure, Subclinical Myocardial Damage, and Cardiac Events: Implications for Blood Pressure Control." J Am Coll Cardiol. 2016;68(16):1713-1722.
Sahli MW, Mares JA, Meyers KJ, et al. "Dietary Intake of Lutein and Diabetic Retinopathy in the Atherosclerosis Risk in Communities Study (ARIC)." Ophthalmic Epidemiol. 2016;23(2):99-108.
J Smith G, Felix JF, Morrison AC, et al. "Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure." PLoS Genet. 2016;12(5):e1006034.
Ligthart S, Marzi C, Aslibekyan S, et al. "DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases." Genome Biol. 2016;17(1):255.
Chen BH, Marioni RE, Colicino E, et al. "DNA methylation-based measures of biological age: meta-analysis predicting time to death." Aging (Albany NY). 2016;8(9):1844-1865.
Konety S, Koene RJ, Norby FL, et al. "Echocardiographic Predictors of Sudden Cardiac Death: The Atherosclerosis Risk in Communities Study and Cardiovascular Health Study." Circ Cardiovasc Imaging. 2016;9(8).
Wu B, Guan W. "On Efficient and Accurate Calculation of Significance P-Values for Sequence Kernel Association Testing of Variant Set." Ann Hum Genet. 2016;80(2):123-35.
O'Neal WT, Zhang Z-M, Loehr LR, Chen LYee, Alonso A. "Electrocardiographic Advanced Interatrial Block and Atrial Fibrillation Risk in the General Population." Am J Cardiol. 2016;117(11):1755-9.
O'Neal WT, Wang YGrace, Wu H-T, et al. "Electrocardiographic J Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk In Communities Study)." Am J Cardiol. 2016;118(6):811-815.
Sung YJu, Winkler TW, Manning AK, et al. "An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group." Genet Epidemiol. 2016;40(5):404-15.
Joehanes R, Just AC, Marioni RE, et al. "Epigenetic Signatures of Cigarette Smoking." Circ Cardiovasc Genet. 2016;9(5):436-447.
Banack HR. "Estimating the Time-Varying Joint Effects of Obesity and Smoking on All-Cause Mortality Using Marginal Structural Models." Am J Epidemiol. 2016;183(2):122-9.
Rhee EP, Yang Q, Yu B, et al. "An exome array study of the plasma metabolome." Nat Commun. 2016;7:12360.
Chami N, Chen M-H, Slater AJ, et al. "Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits." Am J Hum Genet. 2016;99(1):8-21.
Rawlings AM, Bandeen-Roche K, Gross AL, et al. "Factor structure of the ARIC-NCS Neuropsychological Battery: An evaluation of invariance across vascular factors and demographic characteristics." Psychol Assess. 2016;28(12):1674-1683.

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