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ARIC Publications

2016
Maheshwari A, Norby FL, Soliman EZ, Adabag S, Whitsel EA, Alonso A. "Low Heart Rate Variability in a 2-Minute Electrocardiogram Recording Is Associated with an Increased Risk of Sudden Cardiac Death in the General Population: The Atherosclerosis Risk in Communities Study." PLoS One. 2016;11(8):e0161648.
Mirabelli MC, Preisser JS, Loehr LR, et al. "Lung function decline over 25 years of follow-up among black and white adults in the ARIC study cohort." Respir Med. 2016;113:57-64.
Kubota Y, London SJ, Cushman M, et al. "Lung function, respiratory symptoms and venous thromboembolism risk: the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2016;14(12):2394-2401.
Henderson CM, Lutsey PL, Misialek JR, Laha TJ, Selvin E, Eckfeldt JH. "Measurement by a Novel LC-MS/MS Methodology Reveals Similar Serum Concentrations of Vitamin D-Binding Protein in Blacks and Whites." Clin Chem. 2016;62(1):179-87.
Liu C, Kraja AT, Smith JA, et al. "Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci." Nat Genet. 2016;48(10):1162-70.
de Vries PS, Chasman DI, Sabater-Lleal M, et al. "A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration." Hum Mol Genet. 2016;25(2):358-70.
van Leeuwen EM, Sabo A, Bis JC, et al. "Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels." J Med Genet. 2016;53(7):441-9.
Postmus I, Warren HR, Trompet S, et al. "Meta-analysis of genome-wide association studies of HDL cholesterol response to statins." J Med Genet. 2016;53(12):835-845.
"Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits." Nat Genet. 2016;48(8):867-76.
Knopman DS, Gottesman RF, Sharrett ARichey, et al. "Mild Cognitive Impairment and Dementia Prevalence: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." Alzheimers Dement (Amst). 2016;2:1-11.
Bayram Y, Karaca E, Akdemir ZCoban, et al. "Molecular etiology of arthrogryposis in multiple families of mostly Turkish origin." J Clin Invest. 2016;126(2):762-78.
Hill WD, Davies G, Harris SE, et al. "Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions." Transl Psychiatry. 2016;6(12):e980.
Harel T, Yesil G, Bayram Y, et al. "Monoallelic and Biallelic Variants in EMC1 Identified in Individuals with Global Developmental Delay, Hypotonia, Scoliosis, and Cerebellar Atrophy." Am J Hum Genet. 2016;98(3):562-570.
Qiao Y, Guallar E, Suri FK, et al. "MR Imaging Measures of Intracranial Atherosclerosis in a Population-based Study." Radiology. 2016;280(3):860-8.
Natarajan P, Bis JC, Bielak LF, et al. "Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis." Circ Cardiovasc Genet. 2016;9(6):511-520.
Tangri N, Grams ME, Levey AS, et al. "Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis." JAMA. 2016;315(2):164-74.
Gori M, Gupta DK, Claggett B, et al. "Natriuretic Peptide and High-Sensitivity Troponin for Cardiovascular Risk Prediction in Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):677-85.
Willeit P, Kaptoge S, Welsh P, et al. "Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis." Lancet Diabetes Endocrinol. 2016;4(10):840-9.
Lu Y, Day FR, Gustafsson S, et al. "New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk." Nat Commun. 2016;7:10495.
Jun G, Ibrahim-Verbaas CA, Vronskaya M, et al. "A novel Alzheimer disease locus located near the gene encoding tau protein." Mol Psychiatry. 2016;21(1):108-17.
Jensen RA, Sim X, Smith A V, et al. "Novel Genetic Loci Associated With Retinal Microvascular Diameter." Circ Cardiovasc Genet. 2016;9(1):45-54.
Adams HHH, Hibar DP, Chouraki V, et al. "Novel genetic loci underlying human intracranial volume identified through genome-wide association." Nat Neurosci. 2016;19(12):1569-1582.
Zhang S, Divaris K, Moss K, et al. "The Novel Locus is Associated with Severe Gingival Inflammation." JDR Clin Trans Res. 2016;1(2):163-170.
Ndumele CE, Matsushita K, Sang Y, et al. "N-Terminal Pro-Brain Natriuretic Peptide and Heart Failure Risk Among Individuals With and Without Obesity: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(7):631-8.
Ndumele CE, Matsushita K, Lazo M, et al. "Obesity and Subtypes of Incident Cardiovascular Disease." J Am Heart Assoc. 2016;5(8).
Lutsey PL, Bengtson LGS, Punjabi NM, et al. "Obstructive Sleep Apnea and 15-Year Cognitive Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Sleep. 2016;39(2):309-16.
Nagayoshi M, Punjabi NM, Selvin E, et al. "Obstructive sleep apnea and incident type 2 diabetes." Sleep Med. 2016;25:156-161.
Bell EJ, Agarwal SK, Cushman M, Heckbert SR, Lutsey PL. "Orthostatic Hypotension and Risk of Venous Thromboembolism in 2 Cohort Studies." Am J Hypertens. 2016;29(5):634-40.
Korada SKrishna C, Zhao D, Gottesman RF, et al. "Parathyroid Hormone and Subclinical Cerebrovascular Disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study." J Stroke Cerebrovasc Dis. 2016;25(4):883-93.
Yao L, Folsom AR, Pankow JS, et al. "Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study." J Hypertens. 2016;34(2):196-203.
Reis JP, Selvin E, Pankow JS, Michos ED, Rebholz CM. "Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Metab. 2016;42(3):162-9.
Kovesdy CP, Coresh JJ, Ballew SH, et al. "Past Decline Versus Current eGFR and Subsequent ESRD Risk." J Am Soc Nephrol. 2016;27(8):2447-55.
Naimark DMJ, Grams ME, Matsushita K, et al. "Past Decline Versus Current eGFR and Subsequent Mortality Risk." J Am Soc Nephrol. 2016;27(8):2456-66.
Florido R, Zhao D, Ndumele CE, et al. "Physical Activity, Parental History of Premature Coronary Heart Disease, and Incident Atherosclerotic Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2016;5(9).
Folsom AR, Gottesman RF, Appiah D, Shahar E. "Plasma d-Dimer and Incident Ischemic Stroke and Coronary Heart Disease: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(1):18-23.
Li D, Misialek JR, Boerwinkle E, et al. "Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive Study (ARIC-NCS)." Alzheimers Dement (Amst). 2016;3:73-82.
Eicher JD, Chami N, Kacprowski T, et al. "Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals." Am J Hum Genet. 2016;99(1):40-55.
White J, Beck CR, Harel T, et al. "POGZ truncating alleles cause syndromic intellectual disability." Genome Med. 2016;8(1):3.
Dearborn JL, Qiao Y, Guallar E, Steffen LM, Gottesman RF, Zhang Y. "Polyunsaturated fats, carbohydrates and carotid disease: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI study." Atherosclerosis. 2016;251:361-366.
Loehr LR, Meyer ML, Poon AK, et al. "Prediabetes and Diabetes Are Associated With Arterial Stiffness in Older Adults: The ARIC Study." Am J Hypertens. 2016;29(9):1038-45.
Campbell W, Ganna A, Ingelsson E. "Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models." J Clin Epidemiol. 2016;69:89-95.
Santos ABS, Gupta DK, Bello NA, et al. "Prehypertension is Associated With Abnormalities of Cardiac Structure and Function in the Atherosclerosis Risk in Communities Study." Am J Hypertens. 2016;29(5):568-74.
Suri MFareed K, Qiao Y, Ma X, et al. "Prevalence of Intracranial Atherosclerotic Stenosis Using High-Resolution Magnetic Resonance Angiography in the General Population: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(5):1187-93.
Ried JS, M JJeff, Chu AY, et al. "A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape." Nat Commun. 2016;7:13357.
Santos M, Kitzman DW, Matsushita K, Loehr LR, Sueta CA. "Prognostic Importance of Dyspnea for Cardiovascular Outcomes and Mortality in Persons without Prevalent Cardiopulmonary Disease: The Atherosclerosis Risk in Communities Study." PLoS One. 2016;11(10):e0165111.
Gurka MJ, Vishnu A, Santen RJ. "Progression of Metabolic Syndrome Severity During the Menopausal Transition." J Am Heart Assoc. 2016;5(8).
Folsom AR, Tang W, George KM, Heckbert SR, Maclehose RF, Cushman M. "Prospective study of γ' fibrinogen and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Thromb Res. 2016;139:44-9.
Lazarus B, Chen Y, Wilson FP, Sang Y, Chang AR, Coresh JJ. "Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease." JAMA Intern Med. 2016;176(2):238-46.
Beyhaghi H, Reeve BB, Rodgers JE. "Psychometric Properties of the Four-Item Morisky Green Levine Medication Adherence Scale among Atherosclerosis Risk in Communities (ARIC) Study Participants." Value Health. 2016;19(8):996-1001.
Zhang Z-M, Rautaharju PM, Prineas RJ, et al. "Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(22):2141-8.
Parrinello CM, Sharrett ARichey, Maruthur NM, Bergenstal RM, Grams ME, Coresh JJ. "Racial Differences in and Prognostic Value of Biomarkers of Hyperglycemia." Diabetes Care. 2016;39(4):589-95.
Magnani JW, Norby FL, Agarwal SK, Soliman EZ, Chen LYee, Loehr LR. "Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2016;1(4):433-41.
Lacy ME, Wellenius GA, Carnethon MR, et al. "Racial Differences in the Performance of Existing Risk Prediction Models for Incident Type 2 Diabetes: The CARDIA Study." Diabetes Care. 2016;39(2):285-91.
Kapoor A, Bakshy K, Xu L, et al. "Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
Yu B, Pulit SL, Hwang S-J, et al. "Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk." Circ Cardiovasc Genet. 2016;9(1):64-70.
Olfson E, Saccone NL, Johnson EO, et al. "Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans." Mol Psychiatry. 2016;21(5):601-7.
Kan M, Auer PL, Wang GT, et al. "Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
Zanoni P, Khetarpal SA, Larach DB, et al. "Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease." Science. 2016;351(6278):1166-71.
Lalani SR, Liu P, Rosenfeld JA, et al. "Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations." Am J Hum Genet. 2016;98(2):347-57.
Waikar SS, Sabbisetti V, rnlöv JÄ, et al. "Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies." Nephrol Dial Transplant. 2016;31(9):1460-70.
Rebholz CM, Anderson CAM, Grams ME, et al. "Relationship of the American Heart Association's Impact Goals (Life's Simple 7) With Risk of Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Cohort Study." J Am Heart Assoc. 2016;5(4):e003192.
Meyer ML, Tanaka H, Palta P, et al. "Repeatability of Central and Peripheral Pulse Wave Velocity Measures: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(4):470-5.
Folsom AR, Tang W, Weng L-C, Roetker NS, Cushman M, Basu S. "Replication of a genetic risk score for venous thromboembolism in whites but not in African Americans." J Thromb Haemost. 2016;14(1):83-8.
Seidelmann SB, Claggett B, Bravo PE, et al. "Retinal Vessel Calibers in Predicting Long-Term Cardiovascular Outcomes: The Atherosclerosis Risk in Communities Study." Circulation. 2016;134(18):1328-1338.
Lubin JH, Couper DJ, Lutsey PL, Woodward M, Yatsuya H. "Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
Parrinello CM, Matsushita K, Woodward M, Wagenknecht LE, Coresh JJ. "Risk prediction of major complications in individuals with diabetes: the Atherosclerosis Risk in Communities Study." Diabetes Obes Metab. 2016;18(9):899-906.
Wei P, Cao Y, Zhang Y, Xu Z, Kwak I-Y, Boerwinkle E. "On Robust Association Testing for Quantitative Traits and Rare Variants." G3 (Bethesda). 2016;6(12):3941-3950.
Wu B. "Sequence Kernel Association Test of Multiple Continuous Phenotypes." Genet Epidemiol. 2016;40(2):91-100.
Alonso A, Misialek JR, Michos ED, et al. "Serum 25-hydroxyvitamin D and the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Europace. 2016;18(8):1143-9.
Shrestha S, Lutsey PL, Alonso A, Huang X, Mosley TH. "Serum 25-hydroxyvitamin D concentrations in Mid-adulthood and Parkinson's disease risk." Mov Disord. 2016;31(7):972-8.
Rooney MR, Pankow JS, Sibley SD, Selvin E, Reis JP, Michos ED. "Serum calcium and incident type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Am J Clin Nutr. 2016;104(4):1023-1029.
Fyfe-Johnson AL, Alonso A, Selvin E, Bower JK, Pankow JS, Agarwal SK. "Serum fibroblast growth factor-23 and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) Study." J Hypertens. 2016;34(7):1266-72.
Chen Y, Chang AR, McAdams DeMarco MA, et al. "Serum Potassium, Mortality, and Kidney Outcomes in the Atherosclerosis Risk in Communities Study." Mayo Clin Proc. 2016;91(10):1403-1412.
Kubota Y, McAdams-DeMarco M. "Serum uric acid, gout, and venous thromboembolism: The atherosclerosis risk in communities study." Thromb Res. 2016;144:144-8.
Lee AK, McEvoy JW, Hoogeveen RC, Ballantyne CM. "Severe Hypoglycemia and Elevated High-Sensitivity Cardiac Troponin T in Older Adults With Diabetes: The ARIC Study." J Am Coll Cardiol. 2016;68(12):1370-1.
Lutsey PL, Parrinello CM, Misialek JR, et al. "Short-term Variability of Vitamin D-Related Biomarkers." Clin Chem. 2016;62(12):1647-1653.
McEvoy JW, Chen Y, Ndumele CE, et al. "Six-Year Change in High-Sensitivity Cardiac Troponin T and Risk of Subsequent Coronary Heart Disease, Heart Failure, and Death." JAMA Cardiol. 2016;1(5):519-28.
Lutsey PL, Norby FL, Gottesman RF, et al. "Sleep Apnea, Sleep Duration and Brain MRI Markers of Cerebral Vascular Disease and Alzheimer's Disease: The Atherosclerosis Risk in Communities Study (ARIC)." PLoS One. 2016;11(7):e0158758.
Nadruz W, Claggett B, Gonçalves A, et al. "Smoking and Cardiac Structure and Function in the Elderly: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Cardiovasc Imaging. 2016;9(9):e004950.
Camplain R, Meyer ML, Tanaka H, et al. "Smoking Behaviors and Arterial Stiffness Measured by Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(11):1268-1275.

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