ARIC Publications
NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study." Pharmacogenet Genomics. 2006;16(12):891-9.
"Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study." Hum Mol Genet. 2006;15(10):1640-9.
"The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE." J Clin Endocrinol Metab. 2020;105(1).
"Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study." Clin Pharmacol Ther. 2008;83(1):52-60.
"Severe hypoglycaemia, mild cognitive impairment, dementia and brain volumes in older adults with type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) cohort study." Diabetologia. 2018;61(9):1956-1965.
"The Association of Severe Hypoglycemia With Incident Cardiovascular Events and Mortality in Adults With Type 2 Diabetes." Diabetes Care. 2018;41(1):104-111.
"White blood cell count and incidence of coronary heart disease and ischemic stroke and mortality from cardiovascular disease in African-American and White men and women: atherosclerosis risk in communities study." Am J Epidemiol. 2001;154(8):758-64.
"Severe Hypoglycemia and Risk of Falls in Type 2 Diabetes: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2020;43(9):2060-2065.
"Variants of the insulin receptor substrate-1 and fatty acid binding protein 2 genes and the risk of type 2 diabetes, obesity, and hyperinsulinemia in African-Americans: the Atherosclerosis Risk in Communities Study." Diabetes. 1999;48(9):1868-72.
"Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest." Heart Rhythm. 2014;11(3):471-7.
"Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium." PLoS Genet. 2011;7(7):e1002193.
"Neighbourhood unemployment and all cause mortality: a comparison of six countries." J Epidemiol Community Health. 2005;59(3):231-7.
"Retinal microvascular abnormalities and cognitive decline: the ARIC 14-year follow-up study." Neurology. 2009;73(11):862-8.
"Sex Differences in Cognitive Decline Among US Adults." JAMA Netw Open. 2021;4(2):e210169.
"Association Between Blood Pressure and Later-Life Cognition Among Black and White Individuals." JAMA Neurol. 2020;77(7):810-819.
"Genome-wide association study of blood pressure and hypertension." Nat Genet. 2009;41(6):677-87.
"Racial Differences in Malignant Left Ventricular Hypertrophy and Incidence of Heart Failure: A Multicohort Study." Circulation. 2020;141(12):957-967.
"Reproducibility of extracranial carotid atherosclerotic lesions assessed by B-mode ultrasound: the Atherosclerosis Risk in Communities Study." Ultrasound Med Biol. 1996;22(7):791-9.
"Interaction of the glutathione S-transferase genes and cigarette smoking on risk of lower extremity arterial disease: the Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2001;154(3):729-38.
"Association of N-terminal pro B-type natriuretic peptide (NT-proBNP) change with the risk of atrial fibrillation in the ARIC cohort." Am Heart J. 2018;204:119-127.
"Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale." Nat Genet. 2020;52(9):969-983.
" and Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function." J Am Soc Nephrol. 2017;28(3):981-994.
"Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive Study (ARIC-NCS)." Alzheimers Dement (Amst). 2016;3:73-82.
"Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2014;129(9):971-80.
"Germline Cancer Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group." J Natl Cancer Inst. 2021;113(7):875-883.
"Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole-Genome Sequencing Studies." Am J Hum Genet. 2019;104(5):802-814.
"Prospective associations of plasma phospholipids and mild cognitive impairment/dementia among African Americans in the ARIC Neurocognitive Study." Alzheimers Dement (Amst). 2017;6:1-10.
"Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease." Atherosclerosis. 2000;149(2):451-62.
"Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population." Hum Genet. 2018;137(1):85-94.
"Genome-Wide Association of Copy Number Polymorphisms and Kidney Function." PLoS One. 2017;12(1):e0170815.
"Sphingolipids and physical function in the Atherosclerosis Risk in Communities (ARIC) study." Sci Rep. 2021;11(1):1169.
"dbMTS: A comprehensive database of putative human microRNA target site SNVs and their functional predictions." Hum Mutat. 2020;41(6):1123-1130.
"Family risk score of coronary heart disease (CHD) as a predictor of CHD: the Atherosclerosis Risk in Communities (ARIC) study and the NHLBI family heart study." Genet Epidemiol. 2000;18(3):236-50.
"Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease." Nat Genet. 2015;47(6):640-2.
"Independent Association of Plasma Hydroxysphingomyelins With Physical Function in the Atherosclerosis Risk in Communities (ARIC) Study." J Gerontol A Biol Sci Med Sci. 2018;73(8):1103-1110.
"Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS)." Int J Mol Sci. 2019;20(7).
"Plasma phospholipid very-long-chain SFAs in midlife and 20-year cognitive change in the Atherosclerosis Risk in Communities (ARIC): a cohort study." Am J Clin Nutr. 2020;111(6):1252-1258.
"B-mode-detected carotid artery plaque in a general population. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Stroke. 1994;25(12):2377-83.
"6-year change in high sensitivity cardiac troponin T and the risk of atrial fibrillation in the Atherosclerosis Risk in Communities cohort." Clin Cardiol. 2021;44(11):1594-1601.
"Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism." Sci Rep. 2017;7(1):2812.
"Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level." Am J Hum Genet. 2019;105(5):1057-1068.
"Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations." PLoS Genet. 2018;14(5):e1007345.
"Association of a Biomarker of Glucose Peaks, 1,5-Anhydroglucitol, With Subclinical Cardiovascular Disease." Diabetes Care. 2016;39(10):1752-9.
"Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations." PLoS Genet. 2017;13(5):e1006728.
"Association of cardiac autonomic function and the development of hypertension: the ARIC study." Am J Hypertens. 1996;9(12 Pt 1):1147-56.
"Arterial stiffness and the development of hypertension. The ARIC study." Hypertension. 1999;34(2):201-6.
"Lower pulmonary function and cerebral subclinical abnormalities detected by MRI: the Atherosclerosis Risk in Communities study." Chest. 1999;116(1):150-6.
"Association of criteria pollutants with plasma hemostatic/inflammatory markers: a population-based study." J Expo Anal Environ Epidemiol. 2005;15(4):319-28.
"Is low magnesium concentration a risk factor for coronary heart disease? The Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 1998;136(3):480-90.
"A computer algorithm to impute interrupted heart rate data for the spectral analysis of heart rate variability--the ARIC study." Comput Biomed Res. 1996;29(2):140-51.
"Presence and severity of cerebral white matter lesions and hypertension, its treatment, and its control. The ARIC Study. Atherosclerosis Risk in Communities Study." Stroke. 1996;27(12):2262-70.
"Age, race, and sex differences in autonomic cardiac function measured by spectral analysis of heart rate variability--the ARIC study. Atherosclerosis Risk in Communities." Am J Cardiol. 1995;76(12):906-12.
"Multiple metabolic syndrome is associated with lower heart rate variability. The Atherosclerosis Risk in Communities Study." Diabetes Care. 1998;21(12):2116-22.
"Cardiac autonomic function and incident coronary heart disease: a population-based case-cohort study. The ARIC Study. Atherosclerosis Risk in Communities Study." Am J Epidemiol. 1997;145(8):696-706.
"Association of higher levels of ambient criteria pollutants with impaired cardiac autonomic control: a population-based study." Am J Epidemiol. 2004;159(8):768-77.
"Association of vagal tone with serum insulin, glucose, and diabetes mellitus--The ARIC Study." Diabetes Res Clin Pract. 1995;30(3):211-21.
"Lower heart rate variability is associated with the development of coronary heart disease in individuals with diabetes: the atherosclerosis risk in communities (ARIC) study." Diabetes. 2002;51(12):3524-31.
"Population-based study of heart rate variability and prevalent myocardial infarction. The Atherosclerosis Risk in Communities Study." J Electrocardiol. 1996;29(3):189-98.
"The prevalence and severity of white matter lesions, their relationship with age, ethnicity, gender, and cardiovascular disease risk factors: the ARIC Study." Neuroepidemiology. 1997;16(3):149-62.
"Genetic predisposition to higher blood pressure increases coronary artery disease risk." Hypertension. 2013;61(5):995-1001.
"Elevated fasting insulin predicts incident hypertension: the ARIC study. Atherosclerosis Risk in Communities Study Investigators." J Hypertens. 1999;17(8):1169-77.
"Development of the multiple metabolic syndrome in the ARIC cohort: joint contribution of insulin, BMI, and WHR. Atherosclerosis risk in communities." Ann Epidemiol. 1997;7(6):407-16.
"Familial components of the multiple metabolic syndrome: the ARIC study." Diabetologia. 1997;40(8):963-70.
"The relationship between birthweight and early age-related maculopathy: the atherosclerosis risk in communities study." Ophthalmic Epidemiol. 2008;15(1):56-61.
"Apolipoprotein E gene polymorphisms and retinal vascular signs: the atherosclerosis risk in communities (ARIC) study." Arch Ophthalmol. 2007;125(6):813-8.
"Relative importance of systemic determinants of retinal arteriolar and venular caliber: the atherosclerosis risk in communities study." Arch Ophthalmol. 2008;126(10):1404-10.
"Ten-year longitudinal changes in retinal microvascular lesions: the atherosclerosis risk in communities study." Ophthalmology. 2011;118(8):1612-8.
"Low birthweight is associated with narrower arterioles in adults." Hypertension. 2008;51(4):933-8.
"Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders." Am J Hum Genet. 2018;103(5):691-706.
"Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein." PLoS One. 2015;10(3):e0118859.
"Genetic susceptibility, obesity and lifetime risk of type 2 diabetes: The ARIC study and Rotterdam Study." Diabet Med. 2021;38(10):e14639.
"DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases." Genome Biol. 2016;17(1):255.
"Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study." Front Genet. 2019;10:494.
"Association between Dietary Xanthophyll (Lutein and Zeaxanthin) Intake and Early Age-Related Macular Degeneration: The Atherosclerosis Risk in Communities Study." Ophthalmic Epidemiol. 2017;24(5):311-322.
"In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study." Psychoneuroendocrinology. 2018;96:179-187.
"Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study." Heart Rhythm. 2014;11(3):452-7.
"A general framework for integrative analysis of incomplete multiomics data." Genet Epidemiol. 2020;44(7):646-664.
"Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):335-43.
"Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval." Circ Genom Precis Med. 2018;11(5):e002037.
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