ARIC Publications
Obesity and Subtypes of Incident Cardiovascular Disease." J Am Heart Assoc. 2016;5(8).
"Obstructive Sleep Apnea and 15-Year Cognitive Decline: The Atherosclerosis Risk in Communities (ARIC) Study." Sleep. 2016;39(2):309-16.
"Obstructive sleep apnea and incident type 2 diabetes." Sleep Med. 2016;25:156-161.
"Orthostatic Hypotension and Risk of Venous Thromboembolism in 2 Cohort Studies." Am J Hypertens. 2016;29(5):634-40.
"Parathyroid Hormone and Subclinical Cerebrovascular Disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study." J Stroke Cerebrovasc Dis. 2016;25(4):883-93.
"Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study." J Hypertens. 2016;34(2):196-203.
"Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Metab. 2016;42(3):162-9.
"Past Decline Versus Current eGFR and Subsequent ESRD Risk." J Am Soc Nephrol. 2016;27(8):2447-55.
"Past Decline Versus Current eGFR and Subsequent Mortality Risk." J Am Soc Nephrol. 2016;27(8):2456-66.
"Physical Activity, Parental History of Premature Coronary Heart Disease, and Incident Atherosclerotic Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2016;5(9).
"Plasma d-Dimer and Incident Ischemic Stroke and Coronary Heart Disease: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(1):18-23.
"Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive Study (ARIC-NCS)." Alzheimers Dement (Amst). 2016;3:73-82.
"Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals." Am J Hum Genet. 2016;99(1):40-55.
"POGZ truncating alleles cause syndromic intellectual disability." Genome Med. 2016;8(1):3.
"Polyunsaturated fats, carbohydrates and carotid disease: The Atherosclerosis Risk in Communities (ARIC) Carotid MRI study." Atherosclerosis. 2016;251:361-366.
"Prediabetes and Diabetes Are Associated With Arterial Stiffness in Older Adults: The ARIC Study." Am J Hypertens. 2016;29(9):1038-45.
"Prediction impact curve is a new measure integrating intervention effects in the evaluation of risk models." J Clin Epidemiol. 2016;69:89-95.
"Prehypertension is Associated With Abnormalities of Cardiac Structure and Function in the Atherosclerosis Risk in Communities Study." Am J Hypertens. 2016;29(5):568-74.
"Prevalence of Intracranial Atherosclerotic Stenosis Using High-Resolution Magnetic Resonance Angiography in the General Population: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(5):1187-93.
"A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape." Nat Commun. 2016;7:13357.
"Prognostic Importance of Dyspnea for Cardiovascular Outcomes and Mortality in Persons without Prevalent Cardiopulmonary Disease: The Atherosclerosis Risk in Communities Study." PLoS One. 2016;11(10):e0165111.
"Progression of Metabolic Syndrome Severity During the Menopausal Transition." J Am Heart Assoc. 2016;5(8).
"Prospective study of γ' fibrinogen and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Thromb Res. 2016;139:44-9.
"Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease." JAMA Intern Med. 2016;176(2):238-46.
"Psychometric Properties of the Four-Item Morisky Green Levine Medication Adherence Scale among Atherosclerosis Risk in Communities (ARIC) Study Participants." Value Health. 2016;19(8):996-1001.
"Race and Sex Differences in the Incidence and Prognostic Significance of Silent Myocardial Infarction in the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(22):2141-8.
"Racial Differences in and Prognostic Value of Biomarkers of Hyperglycemia." Diabetes Care. 2016;39(4):589-95.
"Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2016;1(4):433-41.
"Racial Differences in the Performance of Existing Risk Prediction Models for Incident Type 2 Diabetes: The CARDIA Study." Diabetes Care. 2016;39(2):285-91.
"Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
"Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk." Circ Cardiovasc Genet. 2016;9(1):64-70.
"Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans." Mol Psychiatry. 2016;21(5):601-7.
"Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
"Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease." Science. 2016;351(6278):1166-71.
"Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations." Am J Hum Genet. 2016;98(2):347-57.
"Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies." Nephrol Dial Transplant. 2016;31(9):1460-70.
"Relationship of the American Heart Association's Impact Goals (Life's Simple 7) With Risk of Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Cohort Study." J Am Heart Assoc. 2016;5(4):e003192.
"Repeatability of Central and Peripheral Pulse Wave Velocity Measures: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(4):470-5.
"Replication of a genetic risk score for venous thromboembolism in whites but not in African Americans." J Thromb Haemost. 2016;14(1):83-8.
"Retinal Vessel Calibers in Predicting Long-Term Cardiovascular Outcomes: The Atherosclerosis Risk in Communities Study." Circulation. 2016;134(18):1328-1338.
"Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
"Risk prediction of major complications in individuals with diabetes: the Atherosclerosis Risk in Communities Study." Diabetes Obes Metab. 2016;18(9):899-906.
"On Robust Association Testing for Quantitative Traits and Rare Variants." G3 (Bethesda). 2016;6(12):3941-3950.
"Sequence Kernel Association Test of Multiple Continuous Phenotypes." Genet Epidemiol. 2016;40(2):91-100.
"Serum 25-hydroxyvitamin D and the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Europace. 2016;18(8):1143-9.
"Serum 25-hydroxyvitamin D concentrations in Mid-adulthood and Parkinson's disease risk." Mov Disord. 2016;31(7):972-8.
"Serum calcium and incident type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) study." Am J Clin Nutr. 2016;104(4):1023-1029.
"Serum fibroblast growth factor-23 and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) Study." J Hypertens. 2016;34(7):1266-72.
"Serum Potassium, Mortality, and Kidney Outcomes in the Atherosclerosis Risk in Communities Study." Mayo Clin Proc. 2016;91(10):1403-1412.
"Serum uric acid, gout, and venous thromboembolism: The atherosclerosis risk in communities study." Thromb Res. 2016;144:144-8.
"Severe Hypoglycemia and Elevated High-Sensitivity Cardiac Troponin T in Older Adults With Diabetes: The ARIC Study." J Am Coll Cardiol. 2016;68(12):1370-1.
"Short-term Variability of Vitamin D-Related Biomarkers." Clin Chem. 2016;62(12):1647-1653.
"Six-Year Change in High-Sensitivity Cardiac Troponin T and Risk of Subsequent Coronary Heart Disease, Heart Failure, and Death." JAMA Cardiol. 2016;1(5):519-28.
"Sleep Apnea, Sleep Duration and Brain MRI Markers of Cerebral Vascular Disease and Alzheimer's Disease: The Atherosclerosis Risk in Communities Study (ARIC)." PLoS One. 2016;11(7):e0158758.
"Smoking and Cardiac Structure and Function in the Elderly: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Cardiovasc Imaging. 2016;9(9):e004950.
"Smoking Behaviors and Arterial Stiffness Measured by Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(11):1268-1275.
"Social support and cognition in a community-based cohort: the Atherosclerosis Risk in Communities (ARIC) study." Age Ageing. 2016;45(4):475-80.
"Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies." Psychol Med. 2016;46(8):1613-23.
"Spousal Influence on Physical Activity in Middle-Aged and Older Adults: The ARIC Study." Am J Epidemiol. 2016;183(5):444-51.
"Temporal Trends in Hospitalization for Acute Decompensated Heart Failure in the United States, 1998-2011." Am J Epidemiol. 2016;183(5):462-70.
"Trajectories of Cardiovascular Risk Factors and Incidence of Atrial Fibrillation Over a 25-Year Follow-Up: The ARIC Study (Atherosclerosis Risk in Communities)." Circulation. 2016;134(8):599-610.
"Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin." Am J Hum Genet. 2016;99(1):56-75.
"Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram." Hum Mol Genet. 2016;25(10):2093-2103.
"USAT: A Unified Score-Based Association Test for Multiple Phenotype-Genotype Analysis." Genet Epidemiol. 2016;40(1):20-34.
"WGSA: an annotation pipeline for human genome sequencing studies." J Med Genet. 2016;53(2):111-2.
"Whole Exome Sequencing in Atrial Fibrillation." PLoS Genet. 2016;12(9):e1006284.
"Whole genome sequence analysis of serum amino acid levels." Genome Biol. 2016;17(1):237.
"Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis." Am J Hum Genet. 2016;99(2):481-8.
"Whole-Exome Sequencing in Familial Parkinson Disease." JAMA Neurol. 2016;73(1):68-75.
"25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms and incident coronary heart disease among whites and blacks: The ARIC study." Atherosclerosis. 2015;241(1):12-7.
"The 25-hydroxyvitamin D3 C-3 epimer: distribution, correlates, and reclassification of 25-hydroxyvitamin D status in the population-based Atherosclerosis Risk in Communities Study (ARIC)." Clin Chim Acta. 2015;442:75-81.
"Actionable exomic incidental findings in 6503 participants: challenges of variant classification." Genome Res. 2015;25(3):305-15.
"African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans." Invest Ophthalmol Vis Sci. 2015;56(6):3999-4005.
"Alcohol consumption and risk of heart failure: the Atherosclerosis Risk in Communities Study." Eur Heart J. 2015;36(15):939-45.
"American Heart Association's Life's Simple 7 and incidence of venous thromboembolism." Am J Hematol. 2015;90(5):E92.
"American Heart Association's Life's Simple 7: Avoiding Heart Failure and Preserving Cardiac Structure and Function." Am J Med. 2015;128(9):970-6.e2.
"The amyloidogenic V122I transthyretin variant in elderly black Americans." N Engl J Med. 2015;372(1):21-9.
"Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease." Nat Genet. 2015;47(6):640-2.
"Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling." J Am Stat Assoc. 2015;110(510):560-572.
"Application of Latent Variable Methods to the Study of Cognitive Decline When Tests Change over Time." Epidemiology. 2015;26(6):878-87.
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