ARIC Publications
Individual components of the Romhilt-Estes left ventricular hypertrophy score differ in their prediction of cardiovascular events: The Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2015;170(6):1220-6.
"The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2015;11(10):e1005378.
"Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children." Nat Commun. 2015;6:7553.
"Integrative pathway genomics of lung function and airflow obstruction." Hum Mol Genet. 2015;24(23):6836-48.
"Kidney Failure and ESRD in the Atherosclerosis Risk in Communities (ARIC) Study: Comparing Ascertainment of Treated and Untreated Kidney Failure in a Cohort Study." Am J Kidney Dis. 2015;66(2):231-9.
"Kidney measures with diabetes and hypertension on cardiovascular disease: the Atherosclerosis Risk in Communities Study." Am J Nephrol. 2015;41(4-5):409-17.
"Lack of association of plasma factor XI with incident stroke and coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2015;243(1):181-5.
"Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair." Nat Genet. 2015;47(11):1294-1303.
"Left ventricular hypertrophy and cardiovascular disease risk prediction and reclassification in blacks and whites: the Atherosclerosis Risk in Communities Study." Am Heart J. 2015;169(1):155-61.e5.
"Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease." Alzheimers Dement. 2015;11(12):1397-1406.
"Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study." Atherosclerosis. 2015;241(2):641-8.
"Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction." Circ Cardiovasc Genet. 2015;8(4):544-52.
"Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility." Nat Commun. 2015;6:5897.
"Medication Adherence Based on Part D Claims for Patients With Heart Failure After Hospitalization (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2015;116(3):413-9.
"Mendelian randomization of blood lipids for coronary heart disease." Eur Heart J. 2015;36(9):539-50.
"Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism." Am J Hum Genet. 2015;96(4):532-42.
"Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans." Stroke. 2015;46(8):2063-8.
"A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):591-601.
"A Meta-analysis of the Association of Estimated GFR, Albuminuria, Diabetes Mellitus, and Hypertension With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):602-12.
"Metabolomics and Incidence of Atrial Fibrillation in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study." PLoS One. 2015;10(11):e0142610.
"Midlife Alcohol Consumption and the Risk of Stroke in the Atherosclerosis Risk in Communities Study." Stroke. 2015;46(11):3124-30.
"Modulation of genetic associations with serum urate levels by body-mass-index in humans." PLoS One. 2015;10(3):e0119752.
"Molecular mechanisms underlying variations in lung function: a systems genetics analysis." Lancet Respir Med. 2015;3(10):782-95.
"Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI." Circ Cardiovasc Genet. 2015;8(2):398-409.
"Nephrolithiasis as a Risk Factor for CKD: The Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(11):2023-9.
"New genetic loci link adipose and insulin biology to body fat distribution." Nature. 2015;518(7538):187-196.
"Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study." Alzheimer Dis Assoc Disord. 2015;29(1):32-44.
"N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) and Risk of Hypertension in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2015;28(10):1262-6.
"Obesity, Insulin Resistance, and Incident Small Vessel Disease on Magnetic Resonance Imaging: Atherosclerosis Risk in Communities Study." Stroke. 2015;46(11):3131-6.
"Obesity related risk of sudden cardiac death in the atherosclerosis risk in communities study." Heart. 2015;101(3):215-21.
"Oxidative Stress and IgG Antibody Modify Periodontitis-CRP Association." J Dent Res. 2015;94(12):1698-705.
"Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
"Patterns and determinants of temporal change in high-sensitivity cardiac troponin-T: The Atherosclerosis Risk in Communities Cohort Study." Int J Cardiol. 2015;187:651-7.
"Periodontitis and retinal microcirculation in the Atherosclerosis Risk in Communities study." J Clin Periodontol. 2015;42(4):342-9.
"Physical Function, Hyperuricemia, and Gout in Older Adults." Arthritis Care Res (Hoboken). 2015;67(12):1730-8.
"Plasma lactate and incident hypertension in the atherosclerosis risk in communities study." Am J Hypertens. 2015;28(2):216-24.
"Plasma Urate and Risk of a Hospital Stay with AKI: The Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(5):776-83.
"PLD3 variants in population studies." Nature. 2015;520(7545):E2-3.
"Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein." PLoS One. 2015;10(3):e0118859.
"Population genomic analysis of 962 whole genome sequences of humans reveals natural selection in non-coding regions." PLoS One. 2015;10(3):e0121644.
"Prevalence of and Racial Disparities in Risk Factor Control in Older Adults With Diabetes: The Atherosclerosis Risk in Communities Study." Diabetes Care. 2015;38(7):1290-8.
"Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone." Circulation. 2015;132(5):402-14.
"Prognostic Significance of High-Sensitivity Cardiac Troponin T Concentrations between the Limit of Blank and Limit of Detection in Community-Dwelling Adults: A Metaanalysis." Clin Chem. 2015;61(12):1524-31.
"Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2015;90(11):1047-51.
"Prospective study of plasma D-dimer and incident venous thromboembolism: The Atherosclerosis Risk in Communities (ARIC) Study." Thromb Res. 2015;136(4):781-5.
"Prospective study of sickle cell trait and venous thromboembolism incidence." J Thromb Haemost. 2015;13(1):2-9.
"P-wave indices and atrial fibrillation: cross-cohort assessments from the Framingham Heart Study (FHS) and Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2015;169(1):53-61.e1.
"Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects." PLoS One. 2015;10(8):e0132626.
"Race and Vitamin D Binding Protein Gene Polymorphisms Modify the Association of 25-Hydroxyvitamin D and Incident Heart Failure: The ARIC (Atherosclerosis Risk in Communities) Study." JACC Heart Fail. 2015;3(5):347-356.
"Race, vitamin D-binding protein gene polymorphisms, 25-hydroxyvitamin D, and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2015;101(6):1232-40.
"Racial differences in circulating natriuretic peptide levels: the atherosclerosis risk in communities study." J Am Heart Assoc. 2015;4(5).
"Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project." JAMA Neurol. 2015;72(7):781-8.
"Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF." Blood. 2015;126(11):e19-29.
"Rare coding variants and X-linked loci associated with age at menarche." Nat Commun. 2015;6:7756.
"Rare variants analysis using penalization methods for whole genome sequence data." BMC Bioinformatics. 2015;16:405.
"Recalibration of blood analytes over 25 years in the atherosclerosis risk in communities study: impact of recalibration on chronic kidney disease prevalence and incidence." Clin Chem. 2015;61(7):938-47.
"Reducing the Blood Pressure-Related Burden of Cardiovascular Disease: Impact of Achievable Improvements in Blood Pressure Prevention and Control." J Am Heart Assoc. 2015;4(10):e002276.
"Relationship between alcohol consumption and cardiac structure and function in the elderly: the Atherosclerosis Risk In Communities Study." Circ Cardiovasc Imaging. 2015;8(6).
"Results from the Atherosclerosis Risk in Communities study suggest that low serum magnesium is associated with incident kidney disease." Kidney Int. 2015;87(4):820-7.
"Retinal microvascular calibre and risk of diabetes mellitus: a systematic review and participant-level meta-analysis." Diabetologia. 2015;58(11):2476-85.
"The Romhilt-Estes left ventricular hypertrophy score and its components predict all-cause mortality in the general population." Am Heart J. 2015;170(1):104-9.
"Secondary findings and carrier test frequencies in a large multiethnic sample." Genome Med. 2015;7(1):54.
"Sequence Kernel Association Analysis of Rare Variant Set Based on the Marginal Regression Model for Binary Traits." Genet Epidemiol. 2015;39(6):399-405.
"Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study." BMC Med Genet. 2015;16:52.
"Serum fibroblast growth factor-23 is associated with incident kidney disease." J Am Soc Nephrol. 2015;26(1):192-200.
"The severity of the metabolic syndrome increases over time within individuals, independent of baseline metabolic syndrome status and medication use: The Atherosclerosis Risk in Communities Study." Atherosclerosis. 2015;243(1):278-85.
"The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1·2 million participants." Lancet Diabetes Endocrinol. 2015;3(6):437-449.
"Sex-Specific Association of Sleep Apnea Severity With Subclinical Myocardial Injury, Ventricular Hypertrophy, and Heart Failure Risk in a Community-Dwelling Cohort: The Atherosclerosis Risk in Communities-Sleep Heart Health Study." Circulation. 2015;132(14):1329-37.
"Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants." Neurology. 2015;84(21):2132-45.
"Six-year change in high-sensitivity C-reactive protein and risk of diabetes, cardiovascular disease, and mortality." Am Heart J. 2015;170(2):380-9.
"Small Brain Lesions and Incident Stroke and Mortality: A Cohort Study." Ann Intern Med. 2015;163(1):22-31.
"Smoking and white matter hyperintensity progression: the ARIC-MRI Study." Neurology. 2015;84(8):841-8.
"Soluble receptor for advanced glycation end products and the risk for incident heart failure: The Atherosclerosis Risk in Communities Study." Am Heart J. 2015;170(5):961-7.
"sRAGE, inflammation, and risk of atrial fibrillation: results from the Atherosclerosis Risk in Communities (ARIC) Study." J Diabetes Complications. 2015;29(2):180-5.
"Statins, plasma cholesterol, and risk of Parkinson's disease: a prospective study." Mov Disord. 2015;30(4):552-9.
"Statistical methods for association tests of multiple continuous traits in genome-wide association studies." Ann Hum Genet. 2015;79(4):282-93.
"Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities." Twin Res Hum Genet. 2015;18(6):738-45.
"Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study." J Clin Periodontol. 2015;42(1):12-20.
"Three-year weight change and cardiometabolic risk factors in obese and normal weight adults who are metabolically healthy: the atherosclerosis risk in communities study." Int J Obes (Lond). 2015;39(8):1203-8.
"Tooth loss, periodontal disease, and cognitive decline in the Atherosclerosis Risk in Communities (ARIC) study." Community Dent Oral Epidemiol. 2015;43(1):47-57.
"