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ARIC Publications

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Journal Article
Tang O, Matsushita K, Coresh JJ, et al. "Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
Bentley AR, Sung YJ, Brown MR, et al. "Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids." Nat Genet. 2019;51(4):636-648.
Noordam R, Bos MM, Wang H, et al. "Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration." Nat Commun. 2019;10(1):5121.
Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
Verhaaren BFJ, Debette S, Bis JC, et al. "Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI." Circ Cardiovasc Genet. 2015;8(2):398-409.
Sabater-Lleal M, Huang J, Chasman D, et al. "Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease." Circulation. 2013;128(12):1310-24.
Graff-Radford J, Simino J, Kantarci K, et al. "Neuroimaging Correlates of Cerebral Microbleeds: The ARIC Study (Atherosclerosis Risk in Communities)." Stroke. 2017;48(11):2964-2972.
West NA, B Windham G, Knopman DS, Shibata DK, Coker LH. "Neuroimaging findings in midlife and risk of late-life dementia over 20 years of follow-up." Neurology. 2019;92(9):e917-e923.
Love S-AM, North KE, Zeng D, et al. "Nine-Year Ethanol Intake Trajectories and Their Association With 15-Year Cognitive Decline Among Black and White Adults." Am J Epidemiol. 2020;189(8):788-800.
Selvin E, Francis LMA, Ballantyne CM, et al. "Nontraditional markers of glycemia: associations with microvascular conditions." Diabetes Care. 2011;34(4):960-7.
Schneider ALC, Sharrett ARichey, Gottesman RF, et al. "Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study." Alzheimer Dis Assoc Disord. 2015;29(1):32-44.
Feitosa MF, Kraja AT, Chasman DI, et al. "Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries." PLoS One. 2018;13(6):e0198166.
Hibar DP, Adams HHH, Jahanshad N, et al. "Novel genetic loci associated with hippocampal volume." Nat Commun. 2017;8:13624.
Jensen RA, Sim X, Smith A V, et al. "Novel Genetic Loci Associated With Retinal Microvascular Diameter." Circ Cardiovasc Genet. 2016;9(1):45-54.
Lubitz SA, Lunetta KL, Lin H, et al. "Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese." J Am Coll Cardiol. 2014;63(12):1200-1210.
Matsushita K, Sang Y, Chen J, et al. "Novel "Predictor Patch" Method for Adding Predictors Using Estimates From Outside Datasets - A Proof-of-Concept Study Adding Kidney Measures to Cardiovascular Mortality Prediction." Circ J. 2019;83(9):1876-1882.
Kucharska-Newton AMaria, Palta P, Burgard S, et al. "Operationalizing Frailty in the Atherosclerosis Risk in Communities Study Cohort." J Gerontol A Biol Sci Med Sci. 2017;72(3):382-388.
Jung M, Warren B, Grams M, et al. "Performance of non-traditional hyperglycemia biomarkers by chronic kidney disease status in older adults with diabetes: Results from the Atherosclerosis Risk in Communities Study." J Diabetes. 2018;10(4):276-285.
Seyerle AA, Sitlani CM, Noordam R, et al. "Pharmacogenomics study of thiazide diuretics and QT interval in multi-ethnic populations: the cohorts for heart and aging research in genomic epidemiology." Pharmacogenomics J. 2018;18(2):215-226.
Mertens AJ, Sweeney C, Shahar E, Rosamond WD, Folsom AR. "Physical activity and breast cancer incidence in middle-aged women: a prospective cohort study." Breast Cancer Res Treat. 2006;97(2):209-14.
Burke BTeevan, Köttgen A, Law A, et al. "Physical Function, Hyperuricemia, and Gout in Older Adults." Arthritis Care Res (Hoboken). 2015;67(12):1730-8.
Li D, Misialek JR, Jack CR, et al. "Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS)." Int J Mol Sci. 2019;20(7).
Bush M, Sturmer T, Stearns SC, Simpson RJ, M Brookhart A, Rosamond WD. "Position matters: Validation of medicare hospital claims for myocardial infarction against medical record review in the atherosclerosis risk in communities study." Pharmacoepidemiol Drug Saf. 2018;27(10):1085-1091.
Loehr LR, Meyer ML, Poon AK, et al. "Prediabetes and Diabetes Are Associated With Arterial Stiffness in Older Adults: The ARIC Study." Am J Hypertens. 2016;29(9):1038-45.
Thorvaldsen T, Claggett BL, Shah A, et al. "Predicting Risk in Patients Hospitalized for Acute Decompensated Heart Failure and Preserved Ejection Fraction: The Atherosclerosis Risk in Communities Study Heart Failure Community Surveillance." Circ Heart Fail. 2017;10(12).
Ibrahim-Verbaas CA, Fornage M, Bis JC, et al. "Predicting stroke through genetic risk functions: the CHARGE Risk Score Project." Stroke. 2014;45(2):403-12.
Rodgers JE, Thudium EM, Beyhaghi H, et al. "Predictors of Medication Adherence in the Elderly: The Role of Mental Health." Med Care Res Rev. 2018;75(6):746-761.
Santos ABS, Gupta DK, Bello NA, et al. "Prehypertension is Associated With Abnormalities of Cardiac Structure and Function in the Atherosclerosis Risk in Communities Study." Am J Hypertens. 2016;29(5):568-74.
Rooney MR, Soliman EZ, Lutsey PL, et al. "Prevalence and Characteristics of Subclinical Atrial Fibrillation in a Community-Dwelling Elderly Population: The ARIC Study." Circ Arrhythm Electrophysiol. 2019;12(10):e007390.
Rawlings AM, Sharrett ARichey, Golden SH, Windham BG. "Prevalence and correlates of depressive symptoms in older adults across the glycaemic spectrum: the Atherosclerosis Risk in Communities (ARIC) study." Diabet Med. 2018;35(5):583-587.
Diab N, Daya NR, Juraschek SP, et al. "Prevalence and Risk Factors of Thyroid Dysfunction in Older Adults in the Community." Sci Rep. 2019;9(1):13156.
Parrinello CM, Rastegar I, Godino JG, Miedema MD, Matsushita K. "Prevalence of and Racial Disparities in Risk Factor Control in Older Adults With Diabetes: The Atherosclerosis Risk in Communities Study." Diabetes Care. 2015;38(7):1290-8.
Suri MFareed K, Qiao Y, Ma X, et al. "Prevalence of Intracranial Atherosclerotic Stenosis Using High-Resolution Magnetic Resonance Angiography in the General Population: The Atherosclerosis Risk in Communities Study." Stroke. 2016;47(5):1187-93.
Shah AM, Claggett B, Sweitzer NK, et al. "Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone." Circulation. 2015;132(5):402-14.
Folsom AR, Aleksic N, Wang L, Cushman M, Wu KK, White RH. "Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based study." Arterioscler Thromb Vasc Biol. 2002;22(6):1018-22.
Beyhaghi H, Reeve BB, Rodgers JE. "Psychometric Properties of the Four-Item Morisky Green Levine Medication Adherence Scale among Atherosclerosis Risk in Communities (ARIC) Study Participants." Value Health. 2016;19(8):996-1001.
Teramoto K, Santos M, Claggett B, et al. "Pulmonary vascular dysfunction among people aged over 65 years in the community in the Atherosclerosis Risk In Communities (ARIC) Study: A cross-sectional analysis." PLoS Med. 2020;17(10):e1003361.
Blecker S, Agarwal SK, Chang PP, et al. "Quality of care for heart failure patients hospitalized for any cause." J Am Coll Cardiol. 2014;63(2):123-30.
Vollmer WM, Enright PL, Pedula KL, et al. "Race and gender differences in the effects of smoking on lung function." Chest. 2000;117(3):764-72.
Fernandes-Silva MM, Shah AM, Hegde S, et al. "Race-Related Differences in Left Ventricular Structural and Functional Remodeling in Response to Increased Afterload: The ARIC Study." JACC Heart Fail. 2017;5(3):157-165.
Qiao Y, Suri FK, Zhang Y, et al. "Racial Differences in Prevalence and Risk for Intracranial Atherosclerosis in a US Community-Based Population." JAMA Cardiol. 2017;2(12):1341-1348.
Williams JE, Massing M, Rosamond WD, Sorlie PD, Tyroler HA. "Racial disparities in CHD mortality from 1968-1992 in the state economic areas surrounding the ARIC study communities. Atherosclerosis Risk in Communities." Ann Epidemiol. 1999;9(8):472-80.
Rosenthal EA, Shirts BH, Amendola LM, et al. "Rare loss of function variants in candidate genes and risk of colorectal cancer." Hum Genet. 2018;137(10):795-806.
Kan M, Auer PL, Wang GT, et al. "Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
Shah AM, Cheng S, Skali H, et al. "Rationale and design of a multicenter echocardiographic study to assess the relationship between cardiac structure and function and heart failure risk in a biracial cohort of community-dwelling elderly persons: the Atherosclerosis Risk in Communities stud." Circ Cardiovasc Imaging. 2014;7(1):173-81.
Reich D, Nalls MA, Kao LWH, et al. "Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene." PLoS Genet. 2009;5(1):e1000360.
Maheshwari A, Norby FL, Roetker NS, et al. "Refining Prediction of Atrial Fibrillation-Related Stroke Using the P-CHADS-VASc Score." Circulation. 2019;139(2):180-191.
Caughey MC, Qiao Y, Meyer ML, et al. "Relationship Between Central Artery Stiffness, Brain Arterial Dilation, and White Matter Hyperintensities in Older Adults: The ARIC Study-Brief Report." Arterioscler Thromb Vasc Biol. 2021;41(6):2109-2116.
Mamo SK, Reed NS, Sharrett ARichey, et al. "Relationship Between Domain-Specific Cognitive Function and Speech-in-Noise Performance in Older Adults: The Atherosclerosis Risk in Communities Hearing Pilot Study." Am J Audiol. 2019;28(4):1006-1014.
Wen CPang, Matsushita K, Coresh JJ, et al. "Relative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar." Kidney Int. 2014;86(4):819-27.
Astor BC, A Sharrett R, Coresh J, Chambless LE, Wasserman BA. "Remodeling of carotid arteries detected with MR imaging: atherosclerosis risk in communities carotid MRI study." Radiology. 2010;256(3):879-86.
Nochioka K, Roca GQuerejeta, Claggett B, et al. "Right Ventricular Function, Right Ventricular-Pulmonary Artery Coupling, and Heart Failure Risk in 4 US Communities: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2018;3(10):939-948.
Lubin JH, Couper DJ, Lutsey PL, Woodward M, Yatsuya H. "Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
E Estes H, Zhang Z-M, Li Y, Tereschenko LG. "The Romhilt-Estes left ventricular hypertrophy score and its components predict all-cause mortality in the general population." Am Heart J. 2015;170(1):104-9.
"SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions." Eur Heart J. 2021;42(25):2455-2467.
Ferket BS, van Kempen BJH, Wieberdink RG, et al. "Separate prediction of intracerebral hemorrhage and ischemic stroke." Neurology. 2014;82(20):1804-12.
Bis JC, White CC, Franceschini N, et al. "Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):359-64.
Magnani JW, Brody JA, Prins BP, et al. "Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium." Circ Cardiovasc Genet. 2014;7(3):365-73.
Millen AE, Nie J, Mares JA, et al. "Serum 25-Hydroxyvitamin D Concentrations and Incidence of Age-Related Macular Degeneration: The Atherosclerosis Risk in Communities Study." Invest Ophthalmol Vis Sci. 2019;60(5):1362-1371.
Lu J, Zaimi I, Barber JR, et al. "SES and correlated factors do not explain the association between periodontal disease, edentulism, and cancer risk." Ann Epidemiol. 2019;38:35-41.
Lee AK, McEvoy JW, Hoogeveen RC, Ballantyne CM. "Severe Hypoglycemia and Elevated High-Sensitivity Cardiac Troponin T in Older Adults With Diabetes: The ARIC Study." J Am Coll Cardiol. 2016;68(12):1370-1.
Mongraw-Chaffin ML, Peters SAE, Huxley RR. "The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1·2 million participants." Lancet Diabetes Endocrinol. 2015;3(6):437-449.
Saeed A, Nambi V, Sun W, et al. "Short-Term Global Cardiovascular Disease Risk Prediction in Older Adults." J Am Coll Cardiol. 2018;71(22):2527-2536.
Kim ED, Ballew SH, Tanaka H, Heiss G, Coresh JJ. "Short-Term Prognostic Impact of Arterial Stiffness in Older Adults Without Prevalent Cardiovascular Disease." Hypertension. 2019;74(6):1373-1382.
Poon AK, Meyer ML, Reaven G, et al. "Short-Term Repeatability of Insulin Resistance Indexes in Older Adults: The Atherosclerosis Risk in Communities Study." J Clin Endocrinol Metab. 2018;103(6):2175-2181.
Lutsey PL, Parrinello CM, Misialek JR, et al. "Short-term Variability of Vitamin D-Related Biomarkers." Clin Chem. 2016;62(12):1647-1653.
Buxbaum J, Alexander A, Koziol J, Tagoe C, Fox E, Kitzman D. "Significance of the amyloidogenic transthyretin Val 122 Ile allele in African Americans in the Arteriosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies." Am Heart J. 2010;159(5):864-70.
Alonso A, Krijthe BP, Aspelund T, et al. "Simple risk model predicts incidence of atrial fibrillation in a racially and geographically diverse population: the CHARGE-AF consortium." J Am Heart Assoc. 2013;2(2):e000102.
Walsleben JA, Kapur VK, Newman AB, et al. "Sleep and reported daytime sleepiness in normal subjects: the Sleep Heart Health Study." Sleep. 2004;27(2):293-8.
Lutsey PL, Norby FL, Gottesman RF, et al. "Sleep Apnea, Sleep Duration and Brain MRI Markers of Cerebral Vascular Disease and Alzheimer's Disease: The Atherosclerosis Risk in Communities Study (ARIC)." PLoS One. 2016;11(7):e0158758.
Quan SF, Howard BV, Iber C, et al. "The Sleep Heart Health Study: design, rationale, and methods." Sleep. 1997;20(12):1077-85.
Boland LL, Shahar E, Wong TY, et al. "Sleep-disordered breathing is not associated with the presence of retinal microvascular abnormalities: the Sleep Heart Health Study." Sleep. 2004;27(3):467-73.
Nadruz W, Claggett B, Gonçalves A, et al. "Smoking and Cardiac Structure and Function in the Elderly: The ARIC Study (Atherosclerosis Risk in Communities)." Circ Cardiovasc Imaging. 2016;9(9):e004950.
Agarwal SK, Avery CL, Ballantyne CM, et al. "Sources of variability in measurements of cardiac troponin T in a community-based sample: the atherosclerosis risk in communities study." Clin Chem. 2011;57(6):891-7.
Lin H, Wang M, Brody JA, et al. "Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):335-43.
Davies G, Lam M, Harris SE, et al. "Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function." Nat Commun. 2018;9(1):2098.
Juraschek SP, Daya N, Appel LJ, et al. "Subclinical Cardiovascular Disease and Fall Risk in Older Adults: Results From the Atherosclerosis Risk in Communities Study." J Am Geriatr Soc. 2019;67(9):1795-1802.
Peters U, North KE, Sethupathy P, et al. "A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study." PLoS Genet. 2013;9(1):e1003171.
Walker KA, Gottesman RF, Wu A, et al. "Systemic inflammation during midlife and cognitive change over 20 years: The ARIC Study." Neurology. 2019;92(11):e1256-e1267.
Liu C-T, C Y Ng M, Rybin D, et al. "Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource." Diabetologia. 2012;55(11):2970-84.

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