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ARIC Publications

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Journal Article
Grams ME, Surapaneni A, Ballew SH, et al. " Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis." J Am Soc Nephrol. 2019;30(10):2027-2036.
Ellis J, Lange EM, Li J, et al. "Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans." Hum Genet. 2014;133(8):985-95.
Gonçalves A, Hung C-L, Claggett B, et al. "Left Atrial Structure and Function Across the Spectrum of Cardiovascular Risk in the Elderly: The Atherosclerosis Risk in Communities Study." Circ Cardiovasc Imaging. 2016;9(2):e004010.
Gondalia R, Holliday KM, Baldassari A, et al. "Leukocyte Traits and Exposure to Ambient Particulate Matter Air Pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study." Environ Health Perspect. 2020;128(1):17004.
Xiao Q, Heiss G, Kucharska-Newton A, Bey G, Love S-AM, Whitsel EA. "Life-Course Neighborhood Socioeconomic Status and Cardiovascular Events in Black and White Adults in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2022;191(8):1470-1484.
Commodore-Mensah Y, Mok Y, Gottesman RF, et al. "Life's Simple 7 at Midlife and Risk of Recurrent Cardiovascular Disease and Mortality after Stroke: The ARIC study." J Stroke Cerebrovasc Dis. 2022;31(7):106486.
Ma Y, Floyd JS, Austin TR, et al. "Life's Simple 7 Cardiovascular Health Score in Relation to Arrhythmias on Extended Ambulatory Electrocardiographic Monitoring (from the Multi-Ethnic Study of Atherosclerosis)." Am J Cardiol. 2022;170:63-70.
Pokharel Y, Sun W, Polfus LM, et al. "Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study." Atherosclerosis. 2015;241(2):641-8.
Saeed A, Sun W, Agarwala A, et al. "Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
Ganesh SK, Tragante V, Guo W, et al. "Loci influencing blood pressure identified using a cardiovascular gene-centric array." Hum Mol Genet. 2013;22(8):1663-78.
Wang SY, Tan ASL, Claggett B, et al. "Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(12):1203-1212.
Monda KL, Ballantyne CM, North KE. "Longitudinal impact of physical activity on lipid profiles in middle-aged adults: the Atherosclerosis Risk in Communities Study." J Lipid Res. 2009;50(8):1685-91.
Folsom AR, Lutsey PL, Heckbert SR, et al. "Longitudinal increases in blood biomarkers of inflammation or cardiovascular disease and the incidence of venous thromboembolism." J Thromb Haemost. 2018;16(10):1964-1972.
Petruski-Ivleva N, Viera AJ, Shimbo D, et al. "Longitudinal Patterns of Change in Systolic Blood Pressure and Incidence of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." Hypertension. 2016;67(6):1150-6.
Aggarwal V, Schneider ALC, Selvin E. "Low hemoglobin A(1c) in nondiabetic adults: an elevated risk state?" Diabetes Care. 2012;35(10):2055-60.
Folsom AR, Ma J, Eckfeldt JH, Nieto FJ, Metcalf PA, Barnes RW. "Low serum albumin. Association with diabetes mellitus and other cardiovascular risk factors but not with prevalent cardiovascular disease or carotid artery intima-media thickness. The Atherosclerosis Risk in Communities (ARIC) Study Investigators." Ann Epidemiol. 1995;5(3):186-91.
van der Velde M, Matsushita K, Coresh J, et al. "Lower estimated glomerular filtration rate and higher albuminuria are associated with all-cause and cardiovascular mortality. A collaborative meta-analysis of high-risk population cohorts." Kidney Int. 2011;79(12):1341-52.
Yong F, Heiss G, Couper DJ, Meyer ML, Cheng S. "Measurement Repeatability of Central and Peripheral Blood Pressures: The ARIC Study." Am J Hypertens. 2017;30(10):978-984.
Yoshida Y, Chen Z, Baudier RL, et al. "Menopausal hormone therapy and risk of cardiovascular events in women with prediabetes or type 2 diabetes: A pooled analysis of 2917 postmenopausal women." Atherosclerosis. 2022;344:13-19.
Dehghan A, Dupuis J, Barbalic M, et al. "Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels." Circulation. 2011;123(7):731-8.
Ballantyne CM, Hoogeveen RC, McNeill AM, et al. "Metabolic syndrome risk for cardiovascular disease and diabetes in the ARIC study." Int J Obes (Lond). 2008;32 Suppl 2(Suppl 2):S21-4.
Palta P, Griswold M, Ranadive R, et al. "Midlife Cardiovascular Health and Robust Versus Frail Late-Life Status: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2022;77(6):1222-1229.
Jia X, Sun C, Nambi V, et al. "Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study." Atherosclerosis. 2022;350:82-89.
Knopman DS, Gottesman RF, Sharrett ARichey, et al. "Midlife vascular risk factors and midlife cognitive status in relation to prevalence of mild cognitive impairment and dementia in later life: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2018;14(11):1406-1415.
Tang O, Matsushita K, Coresh JJ, et al. "Mortality Implications of Prediabetes and Diabetes in Older Adults." Diabetes Care. 2020;43(2):382-388.
Ntalla I, Weng L-C, Cartwright JH, et al. "Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction." Nat Commun. 2020;11(1):2542.
Sabater-Lleal M, Huang J, Chasman D, et al. "Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease." Circulation. 2013;128(12):1310-24.
Willeit P, Kaptoge S, Welsh P, et al. "Natriuretic peptides and integrated risk assessment for cardiovascular disease: an individual-participant-data meta-analysis." Lancet Diabetes Endocrinol. 2016;4(10):840-9.
Borrell LN, Diez Roux AV, Rose K, Catellier D, Clark BL. "Neighbourhood characteristics and mortality in the Atherosclerosis Risk in Communities Study." Int J Epidemiol. 2004;33(2):398-407.
Lazo M, Young HJ, Brancati FL, et al. "NH2-terminal pro-brain natriuretic peptide and risk of diabetes." Diabetes. 2013;62(9):3189-93.
Lee CR, North KE, Bray MS, et al. "NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study." Pharmacogenet Genomics. 2006;16(12):891-9.
Astor BC, Shafi T, Hoogeveen RC, et al. "Novel markers of kidney function as predictors of ESRD, cardiovascular disease, and mortality in the general population." Am J Kidney Dis. 2012;59(5):653-62.
Matsushita K, Sang Y, Chen J, et al. "Novel "Predictor Patch" Method for Adding Predictors Using Estimates From Outside Datasets - A Proof-of-Concept Study Adding Kidney Measures to Cardiovascular Mortality Prediction." Circ J. 2019;83(9):1876-1882.
Ndumele CE, Matsushita K, Lazo M, et al. "Obesity and Subtypes of Incident Cardiovascular Disease." J Am Heart Assoc. 2016;5(8).
Raffield LM, Howard AGreen, Graff M, et al. "Obesity Duration, Severity, and Distribution Trajectories and Cardiovascular Disease Risk in the Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2021;10(24):e019946.
Rose KM, Couper D, Eigenbrodt ML, Mosley TH, A Sharrett R, Gottesman RF. "Orthostatic hypotension and cognitive function: the Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2010;34(1):1-7.
Juraschek SP, Daya N, Appel LJ, et al. "Orthostatic Hypotension and Risk of Clinical and Subclinical Cardiovascular Disease in Middle-Aged Adults." J Am Heart Assoc. 2018;7(10).
Rose KM, Eigenbrodt ML, Biga RL, et al. "Orthostatic hypotension predicts mortality in middle-aged adults: the Atherosclerosis Risk In Communities (ARIC) Study." Circulation. 2006;114(7):630-6.
Olden M, Teumer A, Bochud M, et al. "Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium." Am J Kidney Dis. 2013;61(6):889-98.
Folsom AR, Alonso A, Misialek JR, et al. "Parathyroid hormone concentration and risk of cardiovascular diseases: the Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2014;168(3):296-302.
Perry JRb, Day F, Elks CE, et al. "Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche." Nature. 2014;514(7520):92-97.
Xing C, Dupuis J. "Performance of statistical methods on CHARGE targeted sequencing data." BMC Genet. 2014;15:104.
Bell EJ, Lutsey PL, Windham BG, Folsom AR. "Physical activity and cardiovascular disease in African Americans in Atherosclerosis Risk in Communities." Med Sci Sports Exerc. 2013;45(5):901-7.
Kubota Y, Evenson KR, Maclehose RF, Roetker NS, Joshu CE. "Physical Activity and Lifetime Risk of Cardiovascular Disease and Cancer." Med Sci Sports Exerc. 2017;49(8):1599-1605.
Florido R, Zhao D, Ndumele CE, et al. "Physical Activity, Parental History of Premature Coronary Heart Disease, and Incident Atherosclerotic Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2016;5(9).
Hu X, Mok Y, Ding N, et al. "Physical Function and Subsequent Risk of Cardiovascular Events in Older Adults: The Atherosclerosis Risk in Communities Study." J Am Heart Assoc. 2022;11(17):e025780.
Kim H, Caulfield LE, Garcia-Larsen V, Steffen LM, Coresh JJ. "Plant-Based Diets Are Associated With a Lower Risk of Incident Cardiovascular Disease, Cardiovascular Disease Mortality, and All-Cause Mortality in a General Population of Middle-Aged Adults." J Am Heart Assoc. 2019;8(16):e012865.
Ligthart S, de Vries PS, Uitterlinden AG, Hofman A, Franco OH, Chasman DI. "Pleiotropy among common genetic loci identified for cardiometabolic disorders and C-reactive protein." PLoS One. 2015;10(3):e0118859.
Broda G, Davis CE, Pajak A, et al. "Poland and United States Collaborative Study on Cardiovascular Epidemiology. A comparison of HDL cholesterol and its subfractions in populations covered by the United States Atherosclerosis Risk in Communities Study and the Pol-MONICA Project." Arterioscler Thromb Vasc Biol. 1996;16(2):339-49.
Rywik SL, Davis CE, Pajak A, et al. "Poland and U.S. collaborative study on cardiovascular epidemiology hypertension in the community: prevalence, awareness, treatment, and control of hypertension in the Pol-MONICA Project and the U.S. Atherosclerosis Risk in Communities Study." Ann Epidemiol. 1998;8(1):3-13.
Thomas EA, Enduru N, Tin A, et al. "Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke." J Am Heart Assoc. 2022;11(15):e025703.
Folsom AR, Wu KK, Davis CE, Conlan MG, Sorlie PD, Szklo M. "Population correlates of plasma fibrinogen and factor VII, putative cardiovascular risk factors." Atherosclerosis. 1991;91(3):191-205.
Highland HM, Wojcik GL, Graff M, et al. "Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits." Am J Hum Genet. 2022;109(4):669-679.
Liao D, Cooper L, Cai J, et al. "The prevalence and severity of white matter lesions, their relationship with age, ethnicity, gender, and cardiovascular disease risk factors: the ARIC Study." Neuroepidemiology. 1997;16(3):149-62.
Kao LWH, Coresh J, Shuldiner AR, Boerwinkle E, Bray MS, Brancati FL. "Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study." Diabetes. 2003;52(6):1568-72.
Fox ER, Han H, Taylor HA, et al. "The prognostic value of the mitral diastolic filling velocity ratio for all-cause mortality and cardiovascular morbidity in African Americans: the Atherosclerotic Risks in Communities (ARIC) study." Am Heart J. 2006;152(4):749-55.
Roetker NS, Pankow JS, Bressler J, Morrison AC. "Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities)." Circ Genom Precis Med. 2018;11(3):e001937.
Nonterah EA, Crowther NJ, Klipstein-Grobusch K, et al. "Racial and Ethnic Differences in the Association Between Classical Cardiovascular Risk Factors and Common Carotid Intima-Media Thickness: An Individual Participant Data Meta-Analysis." J Am Heart Assoc. 2022;11(15):e023704.
Parrinello CM, Sharrett ARichey, Maruthur NM, Bergenstal RM, Grams ME, Coresh JJ. "Racial Differences in and Prognostic Value of Biomarkers of Hyperglycemia." Diabetes Care. 2016;39(4):589-95.
Magnani JW, Norby FL, Agarwal SK, Soliman EZ, Chen LYee, Loehr LR. "Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2016;1(4):433-41.
Nandakumar P, Lee D, Richard MA, et al. "Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry." J Hypertens. 2017;35(7):1381-1389.
Ahmad MImtiaz, Tk L-A, Anees MAli, Chen LYee, Soliman EZ. "Relation of Electrocardiographic Abnormal P-Wave Axis With Stroke Mortality in the General Population." Am J Cardiol. 2022;180:59-64.
Folsom AR, Conlan MG, Davis CE, Wu KK. "Relations between hemostasis variables and cardiovascular risk factors in middle-aged adults. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Ann Epidemiol. 1992;2(4):481-94.
B Windham G, Harrison KL, Lirette ST, et al. "Relationship Between Midlife Cardiovascular Health and Late-Life Physical Performance: The ARIC Study." J Am Geriatr Soc. 2017;65(5):1012-1018.
Rebholz CM, Anderson CAM, Grams ME, et al. "Relationship of the American Heart Association's Impact Goals (Life's Simple 7) With Risk of Chronic Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Cohort Study." J Am Heart Assoc. 2016;5(4):e003192.
Beck JD, Offenbacher S. "Relationships among clinical measures of periodontal disease and their associations with systemic markers." Ann Periodontol. 2002;7(1):79-89.
Liew G, A Sharrett R, Wang J J, et al. "Relative importance of systemic determinants of retinal arteriolar and venular caliber: the atherosclerosis risk in communities study." Arch Ophthalmol. 2008;126(10):1404-10.
Wen CPang, Matsushita K, Coresh JJ, et al. "Relative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar." Kidney Int. 2014;86(4):819-27.
Saeed A, Feofanova EV, Yu B, et al. "Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease." J Am Coll Cardiol. 2018;72(2):156-169.
Meyer ML, Tanaka H, Palta P, et al. "Repeatability of Central and Peripheral Pulse Wave Velocity Measures: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(4):470-5.
Lesage SR, Mosley TH, Wong TY, et al. "Retinal microvascular abnormalities and cognitive decline: the ARIC 14-year follow-up study." Neurology. 2009;73(11):862-8.
Dobs AS, Nieto FJ, Szklo M, Barnes R, Sharrett AR, Ko WJ. "Risk factors for popliteal and carotid wall thicknesses in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Epidemiol. 1999;150(10):1055-67.
Lubin JH, Couper DJ, Lutsey PL, Woodward M, Yatsuya H. "Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
Alonso A, Mosley TH, Gottesman RF, Catellier D, Sharrett AR, Coresh J. "Risk of dementia hospitalisation associated with cardiovascular risk factors in midlife and older age: the Atherosclerosis Risk in Communities (ARIC) study." J Neurol Neurosurg Psychiatry. 2009;80(11):1194-201.
Yatsuya H, Folsom AR. "Risk of incident cardiovascular disease among users of smokeless tobacco in the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2010;172(5):600-5.
Lee AK, Woodward M, Wang D, et al. "The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE." J Clin Endocrinol Metab. 2020;105(1).
"SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe." Eur Heart J. 2021;42(25):2439-2454.
"SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions." Eur Heart J. 2021;42(25):2455-2467.
Chambless LE, Cummiskey CP, Cui G. "Several methods to assess improvement in risk prediction models: extension to survival analysis." Stat Med. 2011;30(1):22-38.
George KM, Selvin E, Pankow JS, B Windham G. "Sex Differences in the Association of Diabetes With Cardiovascular Disease Outcomes Among African-American and White Participants in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2018;187(3):403-410.