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ARIC Publications

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"Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study." Lancet Neurol. 2016;15(2):174-184.
Tangri N, Grams ME, Levey AS, et al. "Multinational Assessment of Accuracy of Equations for Predicting Risk of Kidney Failure: A Meta-analysis." JAMA. 2016;315(2):164-74.
Ndumele CE, Matsushita K, Sang Y, et al. "N-Terminal Pro-Brain Natriuretic Peptide and Heart Failure Risk Among Individuals With and Without Obesity: The Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2016;133(7):631-8.
Korada SKrishna C, Zhao D, Gottesman RF, et al. "Parathyroid Hormone and Subclinical Cerebrovascular Disease: The Atherosclerosis Risk in Communities Brain Magnetic Resonance Imaging Study." J Stroke Cerebrovasc Dis. 2016;25(4):883-93.
Loehr LR, Meyer ML, Poon AK, et al. "Prediabetes and Diabetes Are Associated With Arterial Stiffness in Older Adults: The ARIC Study." Am J Hypertens. 2016;29(9):1038-45.
Gurka MJ, Vishnu A, Santen RJ. "Progression of Metabolic Syndrome Severity During the Menopausal Transition." J Am Heart Assoc. 2016;5(8).
Lazarus B, Chen Y, Wilson FP, Sang Y, Chang AR, Coresh JJ. "Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease." JAMA Intern Med. 2016;176(2):238-46.
Magnani JW, Norby FL, Agarwal SK, Soliman EZ, Chen LYee, Loehr LR. "Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2016;1(4):433-41.
Lacy ME, Wellenius GA, Carnethon MR, et al. "Racial Differences in the Performance of Existing Risk Prediction Models for Incident Type 2 Diabetes: The CARDIA Study." Diabetes Care. 2016;39(2):285-91.
Lubin JH, Couper DJ, Lutsey PL, Woodward M, Yatsuya H. "Risk of Cardiovascular Disease from Cumulative Cigarette Use and the Impact of Smoking Intensity." Epidemiology. 2016;27(3):395-404.
Parrinello CM, Matsushita K, Woodward M, Wagenknecht LE, Coresh JJ. "Risk prediction of major complications in individuals with diabetes: the Atherosclerosis Risk in Communities Study." Diabetes Obes Metab. 2016;18(9):899-906.
Fyfe-Johnson AL, Alonso A, Selvin E, Bower JK, Pankow JS, Agarwal SK. "Serum fibroblast growth factor-23 and incident hypertension: the Atherosclerosis Risk in Communities (ARIC) Study." J Hypertens. 2016;34(7):1266-72.
Cobb LK, Godino JG, Selvin E, Kucharska-Newton AMaria, Coresh JJ. "Spousal Influence on Physical Activity in Middle-Aged and Older Adults: The ARIC Study." Am J Epidemiol. 2016;183(5):444-51.
Agarwal SK, Wruck L, Quibrera M, et al. "Temporal Trends in Hospitalization for Acute Decompensated Heart Failure in the United States, 1998-2011." Am J Epidemiol. 2016;183(5):462-70.
Norby FL, Soliman EZ, Chen LYee, Bengtson LGS, Loehr LR, Agarwal SK. "Trajectories of Cardiovascular Risk Factors and Incidence of Atrial Fibrillation Over a 25-Year Follow-Up: The ARIC Study (Atherosclerosis Risk in Communities)." Circulation. 2016;134(8):599-610.
Farlow JL, Robak LA, Hetrick K, et al. "Whole-Exome Sequencing in Familial Parkinson Disease." JAMA Neurol. 2016;73(1):68-75.
Lutsey PL, Eckfeldt JH, Ogagarue ER, Folsom AR, Michos ED. "The 25-hydroxyvitamin D3 C-3 epimer: distribution, correlates, and reclassification of 25-hydroxyvitamin D status in the population-based Atherosclerosis Risk in Communities Study (ARIC)." Clin Chim Acta. 2015;442:75-81.
C Quarta C, Buxbaum JN, Shah AM, et al. "The amyloidogenic V122I transthyretin variant in elderly black Americans." N Engl J Med. 2015;372(1):21-9.
Gross AL, Power MC, Albert MS, et al. "Application of Latent Variable Methods to the Study of Cognitive Decline When Tests Change over Time." Epidemiology. 2015;26(6):878-87.
Corrales-Medina VF, Alvarez KN, Weissfeld LA, et al. "Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease." JAMA. 2015;313(3):264-74.
Grubbs V, Vittinghoff E, Beck JD, et al. "Association Between Periodontal Disease and Kidney Function Decline in African Americans: The Jackson Heart Study." J Periodontol. 2015;86(10):1126-32.
Haring B, Misialek JR, Rebholz CM, Petruski-Ivleva N, Gottesman RF, Mosley TH. "Association of Dietary Protein Consumption With Incident Silent Cerebral Infarcts and Stroke: The Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 2015;46(12):3443-50.
Schick UM, Auer PL, Bis JC, et al. "Association of exome sequences with plasma C-reactive protein levels in >9000 participants." Hum Mol Genet. 2015;24(2):559-71.
Kim Y, Matsushita K, Sang Y, et al. "Association of high-sensitivity cardiac troponin T and natriuretic peptide with incident ESRD: the Atherosclerosis Risk in Communities (ARIC) study." Am J Kidney Dis. 2015;65(4):550-8.
Rebholz CM, Astor BC, Grams ME, et al. "Association of plasma levels of soluble receptor for advanced glycation end products and risk of kidney disease: the Atherosclerosis Risk in Communities study." Nephrol Dial Transplant. 2015;30(1):77-83.
Waks JW, Soliman EZ, Henrikson CA, et al. "Beat-to-beat spatiotemporal variability in the T vector is associated with sudden cardiac death in participants without left ventricular hypertrophy: the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2015;4(1):e001357.
Akinkugbe AA, Saraiya VM, Preisser JS, Offenbacher S. "Bias in estimating the cross-sectional smoking, alcohol, obesity and diabetes associations with moderate-severe periodontitis in the Atherosclerosis Risk in Communities study: comparison of full versus partial-mouth estimates." J Clin Periodontol. 2015;42(7):609-21.
Ma L, Keinan A. "Biological knowledge-driven analysis of epistasis in human GWAS with application to lipid traits." Methods Mol Biol. 2015;1253:35-45.
Fretts AM, Follis JL, Nettleton JA, et al. "Consumption of meat is associated with higher fasting glucose and insulin concentrations regardless of glucose and insulin genetic risk scores: a meta-analysis of 50,345 Caucasians." Am J Clin Nutr. 2015;102(5):1266-78.
Joshi PK, Esko T, Mattsson H, et al. "Directional dominance on stature and cognition in diverse human populations." Nature. 2015;523(7561):459-462.
Wei GS, Coady SA, Reis JP, et al. "Duration and Degree of Weight Gain and Incident Diabetes in Younger Versus Middle-Aged Black and White Adults: ARIC, CARDIA, and the Framingham Heart Study." Diabetes Care. 2015;38(11):2042-9.
Kamel H, O'Neal WT, Okin PM, Loehr LR, Alonso A. "Electrocardiographic left atrial abnormality and stroke subtype in the atherosclerosis risk in communities study." Ann Neurol. 2015;78(5):670-8.
Miedema MD, Norby FL, Blaha MJ, Virani SS, Coresh JJ, Ballantyne CM. "Eligibility for statin therapy according to new cholesterol guidelines and prevalent use of medication to lower lipid levels in an older US Cohort: the Atherosclerosis Risk in Communities Study Cohort." JAMA Intern Med. 2015;175(1):138-40.
Sitlani CM, Rice KM, Lumley T, et al. "Generalized estimating equations for genome-wide association studies using longitudinal phenotype data." Stat Med. 2015;34(1):118-30.
Karaca E, Harel T, Pehlivan D, et al. "Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease." Neuron. 2015;88(3):499-513.
Davies G, Armstrong N, Bis JC, et al. "Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949)." Mol Psychiatry. 2015;20(2):183-92.
Holliday EG, Traylor M, Malik R, et al. "Genetic overlap between diagnostic subtypes of ischemic stroke." Stroke. 2015;46(3):615-9.
Debette S, Verbaas CAIbrahim, Bressler J, et al. "Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium." Biol Psychiatry. 2015;77(8):749-63.
Alonso A, Huang X, Mosley TH, Heiss G. "Heart rate variability and the risk of Parkinson disease: The Atherosclerosis Risk in Communities study." Ann Neurol. 2015;77(5):877-83.
McEvoy JW, Chen Y, Nambi V, et al. "High-Sensitivity Cardiac Troponin T and Risk of Hypertension." Circulation. 2015;132(9):825-33.
Rebholz CM, Coresh JJ, Ballew SH, McMahon B, Whelton SP, Selvin E. "Kidney Failure and ESRD in the Atherosclerosis Risk in Communities (ARIC) Study: Comparing Ascertainment of Treated and Untreated Kidney Failure in a Cohort Study." Am J Kidney Dis. 2015;66(2):231-9.
Alexander N, Matsushita K, Sang Y, Ballew S, Mahmoodi BK, Astor BC. "Kidney measures with diabetes and hypertension on cardiovascular disease: the Atherosclerosis Risk in Communities Study." Am J Nephrol. 2015;41(4-5):409-17.
Carty CL, Keene KL, Cheng Y-C, et al. "Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans." Stroke. 2015;46(8):2063-8.
Jones SB, Loehr LR, Avery CL, Gottesman RF, Wruck L, Shahar E. "Midlife Alcohol Consumption and the Risk of Stroke in the Atherosclerosis Risk in Communities Study." Stroke. 2015;46(11):3124-30.
Schneider ALC, Sharrett ARichey, Gottesman RF, et al. "Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study." Alzheimer Dis Assoc Disord. 2015;29(1):32-44.
Bower JK, Lazo M, Matsushita K, Rubin J, Hoogeveen RC, Ballantyne CM. "N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) and Risk of Hypertension in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2015;28(10):1262-6.
McEvoy JW, Lazo M, Chen Y, et al. "Patterns and determinants of temporal change in high-sensitivity cardiac troponin-T: The Atherosclerosis Risk in Communities Cohort Study." Int J Cardiol. 2015;187:651-7.
Boillot A, Bouchard P, Moss K, Offenbacher S. "Periodontitis and retinal microcirculation in the Atherosclerosis Risk in Communities study." J Clin Periodontol. 2015;42(4):342-9.
Juraschek SP, Bower JK, Selvin E, Shantha GPalamaner, Hoogeveen RC, Ballantyne CM. "Plasma lactate and incident hypertension in the atherosclerosis risk in communities study." Am J Hypertens. 2015;28(2):216-24.
Magnani JW, Zhu L, Norby FL, et al. "P-wave indices and atrial fibrillation: cross-cohort assessments from the Framingham Heart Study (FHS) and Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2015;169(1):53-61.e1.
Huffman JE, de Vries PS, Morrison AC, et al. "Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF." Blood. 2015;126(11):e19-29.
Parrinello CM, Grams ME, Couper DJ, et al. "Recalibration of blood analytes over 25 years in the atherosclerosis risk in communities study: impact of recalibration on chronic kidney disease prevalence and incidence." Clin Chem. 2015;61(7):938-47.
E Estes H, Zhang Z-M, Li Y, Tereschenko LG. "The Romhilt-Estes left ventricular hypertrophy score and its components predict all-cause mortality in the general population." Am Heart J. 2015;170(1):104-9.
Rebholz CM, Grams ME, Coresh JJ, et al. "Serum fibroblast growth factor-23 is associated with incident kidney disease." J Am Soc Nephrol. 2015;26(1):192-200.
Vishnu A, Gurka MJ. "The severity of the metabolic syndrome increases over time within individuals, independent of baseline metabolic syndrome status and medication use: The Atherosclerosis Risk in Communities Study." Atherosclerosis. 2015;243(1):278-85.
Mongraw-Chaffin ML, Peters SAE, Huxley RR. "The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1·2 million participants." Lancet Diabetes Endocrinol. 2015;3(6):437-449.
Power MC, Deal JA, Sharrett ARichey, Jack CR, Knopman D, Mosley TH. "Smoking and white matter hyperintensity progression: the ARIC-MRI Study." Neurology. 2015;84(8):841-8.
Rifai MAl, Schneider ALC, Alonso A, et al. "sRAGE, inflammation, and risk of atrial fibrillation: results from the Atherosclerosis Risk in Communities (ARIC) Study." J Diabetes Complications. 2015;29(2):180-5.
Huang X, Alonso A, Guo X, et al. "Statins, plasma cholesterol, and risk of Parkinson's disease: a prospective study." Mov Disord. 2015;30(4):552-9.
Sanders AE, Divaris K, Naorungroj S, Heiss G. "Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study." J Clin Periodontol. 2015;42(1):12-20.
Shungin D, Cornelis MC, Divaris K, et al. "Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium." Int J Epidemiol. 2015;44(2):638-50.
Knopman DS, Griswold ME, Lirette ST, et al. "Vascular imaging abnormalities and cognition: mediation by cortical volume in nondemented individuals: atherosclerosis risk in communities-neurocognitive study." Stroke. 2015;46(2):433-40.
Hofer E, Cavalieri M, Bis JC, et al. "White Matter Lesion Progression: Genome-Wide Search for Genetic Influences." Stroke. 2015;46(11):3048-57.
London SJ, Gao W, Gharib SA, et al. "ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):350-8.
M Gore O, Seliger SL, Defilippi CR, et al. "Age- and sex-dependent upper reference limits for the high-sensitivity cardiac troponin T assay." J Am Coll Cardiol. 2014;63(14):1441-8.
Li J, Agarwal SK, Alonso A, et al. "Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2014;129(9):971-80.
Kucharska-Newton AMaria, Williams JE, Chang PP, Stearns SC, Sueta CA, Blecker SB. "Anger proneness, gender, and the risk of heart failure." J Card Fail. 2014;20(12):1020-6.
Ndumele CE, Matsushita K, Astor B, et al. "Apolipoproteins do not add prognostic information beyond lipoprotein cholesterol measures among individuals with obesity and insulin resistance syndromes: the ARIC study." Eur J Prev Cardiol. 2014;21(7):866-75.
Ageno W, Di Minno MND, Ay C, et al. "Association between the metabolic syndrome, its individual components, and unprovoked venous thromboembolism: results of a patient-level meta-analysis." Arterioscler Thromb Vasc Biol. 2014;34(11):2478-85.
Selvin E, Rawlings AM, Grams M, Klein R, Steffes M. "Association of 1,5-anhydroglucitol with diabetes and microvascular conditions." Clin Chem. 2014;60(11):1409-18.
Cornes BK, Brody JA, Nikpoor N, et al. "Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):374-382.
Peloso GM, Auer PL, Bis JC, et al. "Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks." Am J Hum Genet. 2014;94(2):223-32.
Alonso A, Jensen PN, Norby FL, Chen LYee, Psaty BM, Folsom AR. "Association of sick sinus syndrome with incident cardiovascular disease and mortality: the Atherosclerosis Risk in Communities study and Cardiovascular Health Study." PLoS One. 2014;9(10):e109662.
Naik RP, Derebail VK, Grams ME, et al. "Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans." JAMA. 2014;312(20):2115-25.
Lamprea-Montealegre JA, Sharrett ARichey, Matsushita K, Selvin E, Szklo M. "Chronic kidney disease, lipids and apolipoproteins, and coronary heart disease: the ARIC study." Atherosclerosis. 2014;234(1):42-6.
Rhodin K, Divaris K, North KE, Barros SP, Moss K, Beck JD. "Chronic periodontitis genome-wide association studies: gene-centric and gene set enrichment analyses." J Dent Res. 2014;93(9):882-90.
Alonso A, Misialek JR, Eckfeldt JH, et al. "Circulating fibroblast growth factor-23 and the incidence of atrial fibrillation: the Atherosclerosis Risk in Communities study." J Am Heart Assoc. 2014;3(5):e001082.
Ilkhanoff L, Arking DE, Lemaitre RN, et al. "A common SCN5A variant is associated with PR interval and atrial fibrillation among African Americans." J Cardiovasc Electrophysiol. 2014;25(11):1150-7.
Bengtson LGS, Kucharska-Newton AMaria, Wruck LM, et al. "Comparable ascertainment of newly-diagnosed atrial fibrillation using active cohort follow-up versus surveillance of centers for medicare and medicaid services in the atherosclerosis risk in communities study." PLoS One. 2014;9(4):e94321.
Coresh JJ, Turin TChowdhury, Matsushita K, et al. "Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality." JAMA. 2014;311(24):2518-2531.