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ARIC Publications

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Weng L-C, Cushman M, Pankow JS, Basu S, Boerwinkle E, Folsom AR. "A genetic association study of activated partial thromboplastin time in European Americans and African Americans: the ARIC Study." Hum Mol Genet. 2015;24(8):2401-8.
Tin A, Köttgen A, Folsom AR, et al. "Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study." BMC Genet. 2015;16:56.
Maruthur NM, Li M, Halushka MK, et al. "Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study." PLoS One. 2015;10(6):e0128452.
Dong J, Yang J, Tranah G, et al. "Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults." Medicine (Baltimore). 2015;94(47):e1892.
Tin A, Grams ME, Maruthur NM, et al. "Hemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study." Clin J Am Soc Nephrol. 2015;10(5):784-90.
Miedema MD, Norby FL, Blaha MJ, Virani SS, Coresh JJ, Ballantyne CM. "Implications of the Eighth Joint National Committee Guidelines for the Management of High Blood Pressure for Aging Adults: Atherosclerosis Risk in Communities Study." Hypertension. 2015;66(3):474-80.
Winkler TW, Justice AE, Graff M, et al. "The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study." PLoS Genet. 2015;11(10):e1005378.
Gharib SA, Loth DW, Artigas MSoler, et al. "Integrative pathway genomics of lung function and airflow obstruction." Hum Mol Genet. 2015;24(23):6836-48.
Okwuosa TM, Soliman EZ, Norby FL, Williams KA, Alonso A. "Left ventricular hypertrophy and cardiovascular disease risk prediction and reclassification in blacks and whites: the Atherosclerosis Risk in Communities Study." Am Heart J. 2015;169(1):155-61.e5.
Wessel J, Chu AY, Willems SM, et al. "Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility." Nat Commun. 2015;6:5897.
Grams ME, Sang Y, Ballew SH, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):591-601.
Schneider ALC, Sharrett ARichey, Gottesman RF, et al. "Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study." Alzheimer Dis Assoc Disord. 2015;29(1):32-44.
Zhao J, Zhu Y, Boerwinkle E. "Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
Parrinello CM, Rastegar I, Godino JG, Miedema MD, Matsushita K. "Prevalence of and Racial Disparities in Risk Factor Control in Older Adults With Diabetes: The Atherosclerosis Risk in Communities Study." Diabetes Care. 2015;38(7):1290-8.
Folsom AR, Tang W, Roetker NS, Heckbert SR, Cushman M. "Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2015;90(11):1047-51.
Song J, Chen F, Campos M, et al. "Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects." PLoS One. 2015;10(8):e0132626.
Reis JP, Michos ED, Selvin E, Pankow JS. "Race, vitamin D-binding protein gene polymorphisms, 25-hydroxyvitamin D, and incident diabetes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Clin Nutr. 2015;101(6):1232-40.
Gupta DK, Claggett B, Wells Q, et al. "Racial differences in circulating natriuretic peptide levels: the atherosclerosis risk in communities study." J Am Heart Assoc. 2015;4(5).
Lunetta KL, Day FR, Sulem P, et al. "Rare coding variants and X-linked loci associated with age at menarche." Nat Commun. 2015;6:7756.
Hardy ST, Loehr LR, Butler KR, et al. "Reducing the Blood Pressure-Related Burden of Cardiovascular Disease: Impact of Achievable Improvements in Blood Pressure Prevention and Control." J Am Heart Assoc. 2015;4(10):e002276.
Bressler J, Franceschini N, Demerath EW, Mosley TH, Folsom AR. "Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study." BMC Med Genet. 2015;16:52.
Vishnu A, Gurka MJ. "The severity of the metabolic syndrome increases over time within individuals, independent of baseline metabolic syndrome status and medication use: The Atherosclerosis Risk in Communities Study." Atherosclerosis. 2015;243(1):278-85.
Power MC, Deal JA, Sharrett ARichey, Jack CR, Knopman D, Mosley TH. "Smoking and white matter hyperintensity progression: the ARIC-MRI Study." Neurology. 2015;84(8):841-8.
Sanders AE, Divaris K, Naorungroj S, Heiss G. "Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study." J Clin Periodontol. 2015;42(1):12-20.
Schneider ALC, Lutsey PL, Selvin E, et al. "Vitamin D, vitamin D binding protein gene polymorphisms, race and risk of incident stroke: the Atherosclerosis Risk in Communities (ARIC) study." Eur J Neurol. 2015;22(8):1220-7.
Li J, Agarwal SK, Alonso A, et al. "Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2014;129(9):971-80.
Kucharska-Newton AMaria, Williams JE, Chang PP, Stearns SC, Sueta CA, Blecker SB. "Anger proneness, gender, and the risk of heart failure." J Card Fail. 2014;20(12):1020-6.
Peloso GM, Auer PL, Bis JC, et al. "Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks." Am J Hum Genet. 2014;94(2):223-32.
Bis JC, Destefano A, Liu X, et al. "Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium." PLoS One. 2014;9(6):e99798.
Lawani SO, Demerath EW, Norby FL, Soliman EZ, Huxley RR, Rose KM. "Birth weight and the risk of atrial fibrillation in whites and African Americans: the Atherosclerosis Risk In Communities (ARIC) study." BMC Cardiovasc Disord. 2014;14:69.
Effoe VS, Rodriguez CJ, Wagenknecht LE, Evans GW, Chang PP, Mirabelli MC. "Carotid intima-media thickness is associated with incident heart failure among middle-aged whites and blacks: the Atherosclerosis Risk in Communities study." J Am Heart Assoc. 2014;3(3):e000797.
Holmes MV, Lange LA, Palmer T, et al. "Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
Huxley RR, Bell EJ, Lutsey PL, et al. "A comparative analysis of risk factors for stroke in blacks and whites: the Atherosclerosis Risk in Communities study." Ethn Health. 2014;19(6):601-16.
Scharpf RB, Mireles L, Yang Q, et al. "Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations." BMC Genet. 2014;15:81.
Wood AR, Esko T, Yang J, et al. "Defining the role of common variation in the genomic and biological architecture of adult human height." Nat Genet. 2014;46(11):1173-86.
Fowkes FGR, Murray GD, Butcher I, et al. "Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events." Eur J Prev Cardiol. 2014;21(3):310-20.
Rawlings AM, Sharrett ARichey, Schneider ALC, et al. "Diabetes in midlife and cognitive change over 20 years: a cohort study." Ann Intern Med. 2014;161(11):785-93.
Avery CL, Sitlani CM, Arking DE, et al. "Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval." Pharmacogenomics J. 2014;14(1):6-13.
Qi Q, Kilpeläinen TO, Downer MK, et al. "FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals." Hum Mol Genet. 2014;23(25):6961-72.
Yoneyama S, Guo Y, Lanktree MB, et al. "Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations." Hum Mol Genet. 2014;23(9):2498-510.
Tragante V, Barnes MR, Ganesh SK, et al. "Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci." Am J Hum Genet. 2014;94(3):349-60.
Foroud T, Lai D, Koller D, et al. "Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7." Stroke. 2014;45(11):3194-9.
Mahajan A, Go MJin, Zhang W, et al. "Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility." Nat Genet. 2014;46(3):234-44.
Foraker RE, Rose KM, Chang PP, Suchindran CM, McNeill AM. "Hospital length of stay for incident heart failure: Atherosclerosis Risk in Communities (ARIC) cohort: 1987-2005." J Healthc Qual. 2014;36(1):45-51.
Jensen PN, Gronroos NN, Chen LYee, Folsom AR, deFilippi C, Heckbert SR. "Incidence of and risk factors for sick sinus syndrome in the general population." J Am Coll Cardiol. 2014;64(6):531-8.
Simino J, Kume R, Kraja AT, et al. "Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program." Atherosclerosis. 2014;235(1):84-93.
Ma Y, Tucker KL, Smith CE, et al. "Lipoprotein lipase variants interact with polyunsaturated fatty acids for obesity traits in women: replication in two populations." Nutr Metab Cardiovasc Dis. 2014;24(12):1323-9.
Crosby J, Peloso GM, Auer PL, et al. "Loss-of-function mutations in APOC3, triglycerides, and coronary disease." N Engl J Med. 2014;371(1):22-31.
Hardy DS, Racette SB. "Macronutrient intake as a mediator with FTO to increase body mass index." J Am Coll Nutr. 2014;33(4):256-66.
Chen CTL, Liu C-T, Chen GK, et al. "Meta-analysis of loci associated with age at natural menopause in African-American women." Hum Mol Genet. 2014;23(12):3327-42.
Gottesman RF, Schneider ALC, Albert M, et al. "Midlife hypertension and 20-year cognitive change: the atherosclerosis risk in communities neurocognitive study." JAMA Neurol. 2014;71(10):1218-27.
Chatterjee R, Brancati FL, Shafi T, et al. "Non-traditional risk factors are important contributors to the racial disparity in diabetes risk: the atherosclerosis risk in communities study." J Gen Intern Med. 2014;29(2):290-7.
Hoggart CJ, Venturini G, Mangino M, et al. "Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index." PLoS Genet. 2014;10(7):e1004508.
Lubitz SA, Lunetta KL, Lin H, et al. "Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese." J Am Coll Cardiol. 2014;63(12):1200-1210.
Tabor HK, Auer PL, Jamal SM, et al. "Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results." Am J Hum Genet. 2014;95(2):183-93.
Zhou Z, Yu F, Buchanan A, et al. "Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts." PLoS One. 2014;9(1):e84810.
Ibrahim-Verbaas CA, Fornage M, Bis JC, et al. "Predicting stroke through genetic risk functions: the CHARGE Risk Score Project." Stroke. 2014;45(2):403-12.
Gordon AS, Tabor HK, Johnson AD, et al. "Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset." Hum Mol Genet. 2014;23(8):1957-63.
Rautaharju PM, Zhang Z-M, Haisty WK, et al. "Race- and sex-associated differences in rate-adjusted QT, QTpeak, ST elevation and other regional measures of repolarization: the Atherosclerosis Risk in Communities (ARIC) Study." J Electrocardiol. 2014;47(3):342-50.
Zakai NA, McClure LA, Judd SE, Safford MM, Folsom AR, Lutsey PL. "Racial and regional differences in venous thromboembolism in the United States in 3 cohorts." Circulation. 2014;129(14):1502-9.
Maynard JW, McAdams-Demarco MA, Law A, Kao L, Gelber AC, Coresh JJ. "Racial differences in gout incidence in a population-based cohort: Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2014;179(5):576-83.
Shah AM, Cheng S, Skali H, et al. "Rationale and design of a multicenter echocardiographic study to assess the relationship between cardiac structure and function and heart failure risk in a biracial cohort of community-dwelling elderly persons: the Atherosclerosis Risk in Communities stud." Circ Cardiovasc Imaging. 2014;7(1):173-81.
Wen CPang, Matsushita K, Coresh JJ, et al. "Relative risks of chronic kidney disease for mortality and end-stage renal disease across races are similar." Kidney Int. 2014;86(4):819-27.
Bis JC, White CC, Franceschini N, et al. "Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study." Circ Cardiovasc Genet. 2014;7(3):359-64.
Prizment AE, Yatsuya H, Lutsey PL, Lubin JH, Woodward M, Folsom AR. "Smoking behavior and lung cancer in a biracial cohort: the Atherosclerosis Risk in Communities study." Am J Prev Med. 2014;46(6):624-32.
Misialek JR, Rose KM, Everson-Rose SA, Soliman EZ, Clark CJ, Norby FL. "Socioeconomic status and the incidence of atrial fibrillation in whites and blacks: the Atherosclerosis Risk in Communities (ARIC) study." J Am Heart Assoc. 2014;3(4).
Koton S, Schneider ALC, Rosamond WD, Shahar E, Sang Y, Gottesman RF. "Stroke incidence and mortality trends in US communities, 1987 to 2011." JAMA. 2014;312(3):259-68.
Cheng S, Claggett B, Correia AW, et al. "Temporal trends in the population attributable risk for cardiovascular disease: the Atherosclerosis Risk in Communities Study." Circulation. 2014;130(10):820-8.
Keller MF, Reiner AP, Okada Y, et al. "Trans-ethnic meta-analysis of white blood cell phenotypes." Hum Mol Genet. 2014;23(25):6944-60.
Mayeda ER, Haan MN, Neuhaus J, et al. "Type 2 diabetes and cognitive decline over 14 years in middle-aged African Americans and whites: the ARIC Brain MRI Study." Neuroepidemiology. 2014;43(3-4):220-7.
Lusk CM, Dyson G, Clark AG, et al. "Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study." Hum Genet. 2014;133(9):1105-16.
Schneider ALC, Lutsey PL, Alonso A, et al. "Vitamin D and cognitive function and dementia risk in a biracial cohort: the ARIC Brain MRI Study." Eur J Neurol. 2014;21(9):1211-8, e69-70.
Michos ED, Carson KA, Schneider ALC, et al. "Vitamin D and subclinical cerebrovascular disease: the Atherosclerosis Risk in Communities brain magnetic resonance imaging study." JAMA Neurol. 2014;71(7):863-71.
Fu W, O'Connor TD, Jun G, et al. "Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants." Nature. 2013;493(7431):216-20.
Maxwell TJ, Ballantyne CM, Cheverud JM, Guild CS, Ndumele CE. "APOE modulates the correlation between triglycerides, cholesterol, and CHD through pleiotropy, and gene-by-gene interactions." Genetics. 2013;195(4):1397-405.
Zhang L, Spencer KL, V Voruganti S, et al. "Association of functional polymorphism rs2231142 (Q141K) in the ABCG2 gene with serum uric acid and gout in 4 US populations: the PAGE Study." Am J Epidemiol. 2013;177(9):923-32.
Yu B, Barbalic M, Brautbar A, et al. "Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies." Circ Cardiovasc Genet. 2013;6(1):82-8.
Katz EG, Stevens J, Truesdale KP, Cai J, North KE. "Associations of body mass index with incident hypertension in American white, American black and Chinese Asian adults in early and middle adulthood: the Coronary Artery Risk Development in Young Adults (CARDIA) study, the Atherosclerosis Risk in Communiti." Asia Pac J Clin Nutr. 2013;22(4):626-34.
Dadu RT, Dodge R, Nambi V, et al. "Ceruloplasmin and heart failure in the Atherosclerosis Risk in Communities study." Circ Heart Fail. 2013;6(5):936-43.
Wang QY, Song J, Gibbs RA, Boerwinkle E, Dong JF. "Characterizing polymorphisms and allelic diversity of von Willebrand factor gene in the 1000 Genomes." J Thromb Haemost. 2013;11(2):261-9.