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ARIC Publications

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Kilpeläinen TO, Bentley AR, Noordam R, et al. "Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity." Nat Commun. 2019;10(1):376.
Keller MF, Reiner AP, Okada Y, et al. "Trans-ethnic meta-analysis of white blood cell phenotypes." Hum Mol Genet. 2014;23(25):6944-60.
Katz EG, Stevens J, Truesdale KP, Cai J, North KE. "Associations of body mass index with incident hypertension in American white, American black and Chinese Asian adults in early and middle adulthood: the Coronary Artery Risk Development in Young Adults (CARDIA) study, the Atherosclerosis Risk in Communiti." Asia Pac J Clin Nutr. 2013;22(4):626-34.
Kats D, Patel MD, Palta P, et al. "Social support and cognition in a community-based cohort: the Atherosclerosis Risk in Communities (ARIC) study." Age Ageing. 2016;45(4):475-80.
Kapoor A, Bakshy K, Xu L, et al. "Rare coding TTN variants are associated with electrocardiographic QT interval in the general population." Sci Rep. 2016;6:28356.
Kao LWH, Arking DE, Post W, et al. "Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations." Circulation. 2009;119(7):940-51.
Kan M, Auer PL, Wang GT, et al. "Rare variant associations with waist-to-hip ratio in European-American and African-American women from the NHLBI-Exome Sequencing Project." Eur J Hum Genet. 2016;24(8):1181-7.
Kalbaugh CA, Kucharska-Newton AMaria, Wruck L, et al. "Peripheral Artery Disease Prevalence and Incidence Estimated From Both Outpatient and Inpatient Settings Among Medicare Fee-for-Service Beneficiaries in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2017;6(5).
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Joshi AD, Andersson C, Buch S, et al. "Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies." Gastroenterology. 2016;151(2):351-363.e28.
Johnson EL, Krauss GL, Lee AK, et al. "Association Between Midlife Risk Factors and Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study." JAMA Neurol. 2018;75(11):1375-1382.
Jiang X, O'Reilly PF, Aschard H, et al. "Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels." Nat Commun. 2018;9(1):260.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Jensen PN, Gronroos NN, Chen LYee, Folsom AR, deFilippi C, Heckbert SR. "Incidence of and risk factors for sick sinus syndrome in the general population." J Am Coll Cardiol. 2014;64(6):531-8.
Jensen MK, Jensen RA, Mukamal KJ, et al. "Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium." Hum Mol Genet. 2017;26(11):2156-2163.
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Irvin MR, Sitlani CM, Floyd JS, et al. "Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group." Am J Hypertens. 2019;32(12):1146-1153.
Irvin MR, Sitlani CM, Noordam R, et al. "Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry." Pharmacogenomics J. 2019;19(1):97-108.
Ibrahim-Verbaas CA, Fornage M, Bis JC, et al. "Predicting stroke through genetic risk functions: the CHARGE Risk Score Project." Stroke. 2014;45(2):403-12.
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Huxley RR, Bell EJ, Lutsey PL, et al. "A comparative analysis of risk factors for stroke in blacks and whites: the Atherosclerosis Risk in Communities study." Ethn Health. 2014;19(6):601-16.
Hui X, Matsushita K, Sang Y, Ballew SH, Fulop T. "CKD and cardiovascular disease in the Atherosclerosis Risk in Communities (ARIC) study: interactions with age, sex, and race." Am J Kidney Dis. 2013;62(4):691-702.
Hong J, Hatchell KE, Bradfield JP, et al. "Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations." J Clin Endocrinol Metab. 2018;103(4):1380-1392.
Holmes MV, Lange LA, Palmer T, et al. "Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis." Am J Hum Genet. 2014;94(2):198-208.
Hoggart CJ, Venturini G, Mangino M, et al. "Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index." PLoS Genet. 2014;10(7):e1004508.
Henderson CM, Lutsey PL, Misialek JR, Laha TJ, Selvin E, Eckfeldt JH. "Measurement by a Novel LC-MS/MS Methodology Reveals Similar Serum Concentrations of Vitamin D-Binding Protein in Blacks and Whites." Clin Chem. 2016;62(1):179-87.
Hardy DS, Racette SB. "Macronutrient intake as a mediator with FTO to increase body mass index." J Am Coll Nutr. 2014;33(4):256-66.
Hardy ST, Loehr LR, Butler KR, et al. "Reducing the Blood Pressure-Related Burden of Cardiovascular Disease: Impact of Achievable Improvements in Blood Pressure Prevention and Control." J Am Heart Assoc. 2015;4(10):e002276.
Hahn J, Fu Y-P, Brown MR, et al. "Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium." PLoS One. 2020;15(11):e0230035.
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Gupta DK, Claggett B, Wells Q, et al. "Racial differences in circulating natriuretic peptide levels: the atherosclerosis risk in communities study." J Am Heart Assoc. 2015;4(5).
Grams ME, Sang Y, Ballew SH, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):591-601.
Gottesman RF, Schneider ALC, Albert M, et al. "Midlife hypertension and 20-year cognitive change: the atherosclerosis risk in communities neurocognitive study." JAMA Neurol. 2014;71(10):1218-27.
Gottesman RF, Albert MS, Alonso A, et al. "Associations Between Midlife Vascular Risk Factors and 25-Year Incident Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort." JAMA Neurol. 2017;74(10):1246-1254.
Gottesman RF, Schneider ALC, Zhou Y, et al. "Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition." JAMA. 2017;317(14):1443-1450.
Gordon AS, Tabor HK, Johnson AD, et al. "Quantifying rare, deleterious variation in 12 human cytochrome P450 drug-metabolism genes in a large-scale exome dataset." Hum Mol Genet. 2014;23(8):1957-63.
González HM, Tarraf W, Harrison K, et al. "Midlife cardiovascular health and 20-year cognitive decline: Atherosclerosis Risk in Communities Study results." Alzheimers Dement. 2018;14(5):579-589.
Gharib SA, Loth DW, Artigas MSoler, et al. "Integrative pathway genomics of lung function and airflow obstruction." Hum Mol Genet. 2015;24(23):6836-48.
George KM, Folsom AR, Kucharska-Newton AMaria, Mosley TH. "Factors Related to Differences in Retention among African American and White Participants in the Atherosclerosis Risk in Communities Study (ARIC) Prospective Cohort: 1987-2013." Ethn Dis. 2017;27(1):31-38.
George KM, Lutsey PL, Kucharska-Newton AMaria, Palta P, Heiss G, Osypuk T. "Life-Course Individual and Neighborhood Socioeconomic Status and Risk of Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study." Am J Epidemiol. 2020;189(10):1134-1142.
Gellert KS, Alonso A, Chen LYee, Meyer ML, Soliman EZ, Suzuki T. "Association of Sleep Apnea, Diagnosed by Self-Reported Physician Diagnosis or Hospital Discharge Codes, With Atrial Fibrillation and Ectopy Using Ambulatory Electrocardiogram in the ARIC Study." Circ Arrhythm Electrophysiol. 2020;13(4):e007574.
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Fowkes FGR, Murray GD, Butcher I, et al. "Development and validation of an ankle brachial index risk model for the prediction of cardiovascular events." Eur J Prev Cardiol. 2014;21(3):310-20.
Foroud T, Lai D, Koller D, et al. "Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7." Stroke. 2014;45(11):3194-9.
Folsom AR, Basu S, Hong C-P, Heckbert SR, Lutsey PL, Rosamond WD. "Reasons for Differences in the Incidence of Venous Thromboembolism in Black Versus White Americans." Am J Med. 2019;132(8):970-976.
Folsom AR, Tang W, Weng L-C, Roetker NS, Cushman M, Basu S. "Replication of a genetic risk score for venous thromboembolism in whites but not in African Americans." J Thromb Haemost. 2016;14(1):83-8.
Folsom AR, Tang W, Roetker NS, Heckbert SR, Cushman M. "Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2015;90(11):1047-51.
Fesinmeyer MD, Meigs JB, North KE, et al. "Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study." BMC Med Genet. 2013;14:98.
Fernandes-Silva MM, Shah AM, Hegde S, et al. "Race-Related Differences in Left Ventricular Structural and Functional Remodeling in Response to Increased Afterload: The ARIC Study." JACC Heart Fail. 2017;5(3):157-165.
Feofanova EV, Yu B, Metcalf GA, et al. "Sequence-Based Analysis of Lipid-Related Metabolites in a Multiethnic Study." Genetics. 2018;209(2):607-616.
Fashanu OE, Zhao D, Schneider ALC, et al. "Mid-life serum Vitamin D concentrations were associated with incident dementia but not late-life neuropsychological performance in the Atherosclerosis Risk in Communities (ARIC) Study." BMC Neurol. 2019;19(1):244.
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Evans DS, Avery CL, Nalls MA, et al. "Fine-mapping, novel loci identification, and SNP association transferability in a genome-wide association study of QRS duration in African Americans." Hum Mol Genet. 2016;25(19):4350-4368.
Evangelou E, Gao H, Chu C, et al. "New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders." Nat Hum Behav. 2019;3(9):950-961.
Ellervik C, Roselli C, Christophersen IE, et al. "Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation: A Mendelian Randomization Study." JAMA Cardiol. 2019;4(2):144-152.
Effoe VS, Rodriguez CJ, Wagenknecht LE, Evans GW, Chang PP, Mirabelli MC. "Carotid intima-media thickness is associated with incident heart failure among middle-aged whites and blacks: the Atherosclerosis Risk in Communities study." J Am Heart Assoc. 2014;3(3):e000797.
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Dumitrescu L, Carty CL, Franceschini N, et al. "Post-genome-wide association study challenges for lipid traits: describing age as a modifier of gene-lipid associations in the Population Architecture using Genomics and Epidemiology (PAGE) study." Ann Hum Genet. 2013;77(5):416-25.
Dong J, Wyss A, Yang J, et al. "Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans." Mol Neurobiol. 2017;54(10):8021-8032.
Dong J, Yang J, Tranah G, et al. "Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults." Medicine (Baltimore). 2015;94(47):e1892.
Dong J, Pinto JM, Guo X, et al. "The Prevalence of Anosmia and Associated Factors Among U.S. Black and White Older Adults." J Gerontol A Biol Sci Med Sci. 2017;72(8):1080-1086.
Direk N, Williams S, Smith JA, et al. "An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype." Biol Psychiatry. 2017;82(5):322-329.
Mahajan A, Go MJin, Zhang W, et al. "Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility." Nat Genet. 2014;46(3):234-44.
Demerath EW, Guan W, Grove ML, et al. "Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci." Hum Mol Genet. 2015;24(15):4464-79.
Dearborn-Tomazos JL, Wu A, Steffen LM, et al. "Association of Dietary Patterns in Midlife and Cognitive Function in Later Life in US Adults Without Dementia." JAMA Netw Open. 2019;2(12):e1916641.
Deal JA, Sharrett ARichey, Albert M, et al. "Retinal signs and risk of incident dementia in the Atherosclerosis Risk in Communities study." Alzheimers Dement. 2019;15(3):477-486.
de Vries PS, Yu B, Feofanova EV, et al. "Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study." Hum Mol Genet. 2017;26(17):3442-3450.
de Vries PS, Chasman DI, Sabater-Lleal M, et al. "A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration." Hum Mol Genet. 2016;25(2):358-70.
de Larriva APArenas, Alonso A, Norby FL, Roetker NS. "Circulating ceruloplasmin, ceruloplasmin-associated genes and the incidence of venous thromboembolism in the Atherosclerosis Risk in Communities study." J Thromb Haemost. 2019;17(5):818-826.
Dadu RT, Dodge R, Nambi V, et al. "Ceruloplasmin and heart failure in the Atherosclerosis Risk in Communities study." Circ Heart Fail. 2013;6(5):936-43.
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Cuthbertson CC, Tan X, Heiss G, Kucharska-Newton AMaria, Nichols HB, Kubota Y. "Associations of Leisure-Time Physical Activity and Television Viewing With Life Expectancy Free of Nonfatal Cardiovascular Disease: The ARIC Study." J Am Heart Assoc. 2019;8(18):e012657.
Christophersen IE, Rienstra M, Roselli C, et al. "Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation." Nat Genet. 2017;49(6):946-952.
Chin K, Zhao D, Tibuakuu M, et al. "Physical Activity, Vitamin D, and Incident Atherosclerotic Cardiovascular Disease in Whites and Blacks: The ARIC Study." J Clin Endocrinol Metab. 2017;102(4):1227-1236.
Cheng S, Claggett B, Correia AW, et al. "Temporal trends in the population attributable risk for cardiovascular disease: the Atherosclerosis Risk in Communities Study." Circulation. 2014;130(10):820-8.
Cheng Y-C, Stanne TM, Giese A-K, et al. "Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2." Stroke. 2016;47(2):307-16.
Chen CTL, Liu C-T, Chen GK, et al. "Meta-analysis of loci associated with age at natural menopause in African-American women." Hum Mol Genet. 2014;23(12):3327-42.
Chen J, Spracklen CN, Marenne G, et al. "The trans-ancestral genomic architecture of glycemic traits." Nat Genet. 2021;53(6):840-860.
Chatterjee R, Brancati FL, Shafi T, et al. "Non-traditional risk factors are important contributors to the racial disparity in diabetes risk: the atherosclerosis risk in communities study." J Gen Intern Med. 2014;29(2):290-7.
Chatterjee R, Davenport CA, Raffield LM, et al. "KCNJ11 variants and their effect on the association between serum potassium and diabetes risk in the Atherosclerosis Risk in Communities (ARIC) Study and Jackson Heart Study (JHS) cohorts." PLoS One. 2018;13(8):e0203213.
Chang PP, Wruck LM, Shahar E, et al. "Trends in Hospitalizations and Survival of Acute Decompensated Heart Failure in Four US Communities (2005-2014): ARIC Study Community Surveillance." Circulation. 2018;138(1):12-24.
Caughey MC, Qiao Y, Windham BGwen, Gottesman RF, Mosley TH. "Carotid Intima-Media Thickness and Silent Brain Infarctions in a Biracial Cohort: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2018;31(8):869-875.
Carlson CS, Matise TC, North KE, et al. "Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study." PLoS Biol. 2013;11(9):e1001661.
C Y Ng M, Graff M, Lu Y, et al. "Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium." PLoS Genet. 2017;13(4):e1006719.
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Butler KR, Penman AD, Minor DS. "Determinants of pulse pressure and annual rates of change in the Atherosclerosis Risk in Communities study." J Hypertens. 2015;33(12):2463-70.
Bressler J, Mosley TH, Penman A, et al. "Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study." Am J Med Genet B Neuropsychiatr Genet. 2017;174(3):269-282.
Bressler J, Franceschini N, Demerath EW, Mosley TH, Folsom AR. "Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study." BMC Med Genet. 2015;16:52.
Bressler J, Yu B, Mosley TH, et al. "Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study." Transl Psychiatry. 2017;7(7):e1173.

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