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ARIC Publications

Nambi V, Boerwinkle E, Lawson K, et al. "The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2012;222(1):135-7.
"Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis." Int J Epidemiol. 2012;41(5):1419-33.
Cheng C-Y, Reich D, Haiman CA, et al. "African ancestry and its correlation to type 2 diabetes in African Americans: a genetic admixture analysis in three U.S. population cohorts." PLoS One. 2012;7(3):e32840.
Dreyfus JG, Lutsey PL, Huxley R, et al. "Age at menarche and risk of type 2 diabetes among African-American and white women in the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2012;55(9):2371-80.
M Ikram K, Mitchell P, Klein R, A Sharrett R, Couper DJ, Wong TY. "Age-related macular degeneration and long-term risk of stroke subtypes." Stroke. 2012;43(6):1681-3.
Juraschek SP, Steffes MW, Miller ER, Selvin E. "Alternative markers of hyperglycemia and risk of diabetes." Diabetes Care. 2012;35(11):2265-70.
McAdams-Demarco MA, Maynard JW, Coresh J, Baer AN. "Anemia and the onset of gout in a population-based cohort of adults: Atherosclerosis Risk in Communities study." Arthritis Res Ther. 2012;14(4):R193.
Wattanakit K, Lutsey PL, Bell EJ, et al. "Association between cardiovascular disease risk factors and occurrence of venous thromboembolism. A time-dependent analysis." Thromb Haemost. 2012;108(3):508-15.
Murabito JM, White CC, Kavousi M, et al. "Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies." Circ Cardiovasc Genet. 2012;5(1):100-12.
Goek O-N, Köttgen A, Hoogeveen RC, Ballantyne CM, Coresh J, Astor BC. "Association of apolipoprotein A1 and B with kidney function and chronic kidney disease in two multiethnic population samples." Nephrol Dial Transplant. 2012;27(7):2839-47.
Köttgen A, Yang Q, Shimmin LC, et al. "Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing." PLoS One. 2012;7(5):e38311.
Mahmoodi BK, Gansevoort RT, Næss IAnne, et al. "Association of mild to moderate chronic kidney disease with venous thromboembolism: pooled analysis of five prospective general population cohorts." Circulation. 2012;126(16):1964-71.
Carnethon MR, De Chavez P JD, Biggs ML, et al. "Association of weight status with mortality in adults with incident diabetes." JAMA. 2012;308(6):581-90.
Carty CL, Bůžková P, Fornage M, et al. "Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study." Circ Cardiovasc Genet. 2012;5(2):210-6.
Virani SS, Brautbar A, Davis BC, et al. "Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study." Circulation. 2012;125(2):241-9.
Lopez FL, Agarwal SK, Maclehose RF, et al. "Blood lipid levels, lipid-lowering medications, and the incidence of atrial fibrillation: the atherosclerosis risk in communities study." Circ Arrhythm Electrophysiol. 2012;5(1):155-62.
Stevens J, Truesdale KP, Wang C-H, Cai J, Erber E. "Body mass index at age 25 and all-cause mortality in whites and African Americans: the Atherosclerosis Risk in Communities study." J Adolesc Health. 2012;50(3):221-7.
Yang EY, Chambless L, A Sharrett R, et al. "Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the Atherosclerosis Risk in Communities (ARIC) study." Stroke. 2012;43(1):103-8.
Rubin J, Matsushita K, Ballantyne CM, Hoogeveen R, Coresh J, Selvin E. "Chronic hyperglycemia and subclinical myocardial injury." J Am Coll Cardiol. 2012;59(5):484-9.
Rosamond WD, Chang PP, Baggett C, et al. "Classification of heart failure in the atherosclerosis risk in communities (ARIC) study: a comparison of diagnostic criteria." Circ Heart Fail. 2012;5(2):152-9.
Waheed S, Matsushita K, Sang Y, et al. "Combined association of albuminuria and cystatin C-based estimated GFR with mortality, coronary heart disease, and heart failure outcomes: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2012;60(2):207-16.
Nambi V, Chambless L, He M, et al. "Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study." Eur Heart J. 2012;33(2):183-90.
Bis JC, DeCarli C, Smith A V, et al. "Common variants at 12q14 and 12q24 are associated with hippocampal volume." Nat Genet. 2012;44(5):545-51.
Holliday EG, Maguire JM, Evans T-J, et al. "Common variants at 6p21.1 are associated with large artery atherosclerotic stroke." Nat Genet. 2012;44(10):1147-51.
Matsushita K, Mahmoodi BK, Woodward M, et al. "Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate." JAMA. 2012;307(18):1941-51.
Chanda P, Yuhki N, Li M, et al. "Comprehensive evaluation of imputation performance in African Americans." J Hum Genet. 2012;57(7):411-21.
Windham BG, Griswold ME, Shibata D, Penman A, Catellier DJ, Mosley TH. "Covert neurological symptoms associated with silent infarcts from midlife to older age: the Atherosclerosis Risk in Communities study." Stroke. 2012;43(5):1218-23.
Kaptoge S, Di Angelantonio E, Pennells L, et al. "C-reactive protein, fibrinogen, and cardiovascular disease prediction." N Engl J Med. 2012;367(14):1310-20.
Mongraw-Chaffin ML, Matsushita K, Brancati FL, et al. "Diabetes medication use and blood lactate level among participants with type 2 diabetes: the atherosclerosis risk in communities carotid MRI study." PLoS One. 2012;7(12):e51237.
Franceschini N, van Rooij FJA, Prins BP, et al. "Discovery and fine mapping of serum protein loci through transethnic meta-analysis." Am J Hum Genet. 2012;91(4):744-53.
Schneider ALC, A Sharrett R, Patel MD, et al. "Education and cognitive change over 15 years: the atherosclerosis risk in communities study." J Am Geriatr Soc. 2012;60(10):1847-53.
Folsom AR, Nambi V, Pankow JS, et al. "Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2012;224(2):435-9.
Paynter NP, Crainiceanu CM, A Sharrett R, Chambless LE, Coresh J. "Effect of correcting for long-term variation in major coronary heart disease risk factors: relative hazard estimation and risk prediction in the Atherosclerosis Risk in Communities Study." Ann Epidemiol. 2012;22(3):191-7.
Grallert H, Dupuis J, Bis JC, et al. "Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies." Eur Heart J. 2012;33(2):238-51.
Buyske S, Wu Y, Carty CL, et al. "Evaluation of the metabochip genotyping array in African Americans and implications for fine mapping of GWAS-identified loci: the PAGE study." PLoS One. 2012;7(4):e35651.
Tennessen JA, Bigham AW, O'Connor TD, et al. "Evolution and functional impact of rare coding variation from deep sequencing of human exomes." Science. 2012;337(6090):64-9.
Avery CL, Sethupathy P, Buyske S, et al. "Fine-mapping and initial characterization of QT interval loci in African Americans." PLoS Genet. 2012;8(8):e1002870.
Gronroos NN, Chamberlain AM, Folsom AR, et al. "Fish, fish-derived n-3 fatty acids, and risk of incident atrial fibrillation in the Atherosclerosis Risk in Communities (ARIC) study." PLoS One. 2012;7(5):e36686.
Rapsomaniki E, White IR, Wood AM, Thompson SG. "A framework for quantifying net benefits of alternative prognostic models." Stat Med. 2012;31(2):114-30.
Yang J, Loos RJF, Powell JE, et al. "FTO genotype is associated with phenotypic variability of body mass index." Nature. 2012;490(7419):267-72.
Tang W, Schwienbacher C, Lopez LM, et al. "Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease." Am J Hum Genet. 2012;91(1):152-62.
Wassel CL, Lamina C, Nambi V, et al. "Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium." Atherosclerosis. 2012;222(1):138-47.
Traylor M, Farrall M, Holliday EG, et al. "Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies." Lancet Neurol. 2012;11(11):951-62.
Brautbar A, Pompeii LA, Dehghan A, et al. "A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies." Atherosclerosis. 2012;223(2):421-6.
Manning AK, Hivert M-F, Scott RA, et al. "A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance." Nat Genet. 2012;44(6):659-69.
Pattaro C, Köttgen A, Teumer A, et al. "Genome-wide association and functional follow-up reveals new loci for kidney function." PLoS Genet. 2012;8(3):e1002584.
Huang J, Sabater-Lleal M, Asselbergs FW, et al. "Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation." Blood. 2012;120(24):4873-81.
Imboden M, Bouzigon E, Curjuric I, et al. "Genome-wide association study of lung function decline in adults with and without asthma." J Allergy Clin Immunol. 2012;129(5):1218-28.
Divaris K, Monda KL, North KE, et al. "Genome-wide association study of periodontal pathogen colonization." J Dent Res. 2012;91(7 Suppl):21S-28S.
David SP, Hamidovic A, Chen GK, et al. "Genome-wide meta-analyses of smoking behaviors in African Americans." Transl Psychiatry. 2012;2:e119.
Boraska V, Jerončić A, Colonna V, et al. "Genome-wide meta-analysis of common variant differences between men and women." Hum Mol Genet. 2012;21(21):4805-15.
W Y Yau J, Rogers SL, Kawasaki R, et al. "Global prevalence and major risk factors of diabetic retinopathy." Diabetes Care. 2012;35(3):556-64.
Joshu CE, Prizment AE, Dluzniewski PJ, et al. "Glycated hemoglobin and cancer incidence and mortality in the Atherosclerosis in Communities (ARIC) Study, 1990-2006." Int J Cancer. 2012;131(7):1667-77.
Bower JK, Appel LJ, Matsushita K, et al. "Glycated hemoglobin and risk of hypertension in the atherosclerosis risk in communities study." Diabetes Care. 2012;35(5):1031-7.
Alonso A, Tang W, Agarwal SK, Soliman EZ, Chamberlain AM, Folsom AR. "Hemostatic markers are associated with the risk and prognosis of atrial fibrillation: the ARIC study." Int J Cardiol. 2012;155(2):217-22.
Rubin J, Nambi V, Chambless LE, et al. "Hyperglycemia and arterial stiffness: the Atherosclerosis Risk in the Communities study." Atherosclerosis. 2012;225(1):246-51.
McAdams-Demarco MA, Maynard JW, Baer AN, Coresh J. "Hypertension and the risk of incident gout in a population-based study: the atherosclerosis risk in communities cohort." J Clin Hypertens (Greenwich). 2012;14(10):675-9.
Huxley RR, Yatsuya H, Lutsey PL, Woodward M, Alonso A, Folsom AR. "Impact of age at smoking initiation, dosage, and time since quitting on cardiovascular disease in african americans and whites: the atherosclerosis risk in communities study." Am J Epidemiol. 2012;175(8):816-26.
J Smith G, Avery CL, Evans DS, et al. "Impact of ancestry and common genetic variants on QT interval in African Americans." Circ Cardiovasc Genet. 2012;5(6):647-55.
Billings LK, Hsu Y-H, Ackerman RJ, et al. "Impact of common variation in bone-related genes on type 2 diabetes and related traits." Diabetes. 2012;61(8):2176-86.
Avery CL, Kucharska-Newton A, Monda KL, et al. "Impact of long-term measures of glucose and blood pressure on the retinal microvasculature." Atherosclerosis. 2012;225(2):412-7.
Bijari PB, Antiga L, Gallo D, Wasserman BA, Steinman DA. "Improved prediction of disturbed flow via hemodynamically-inspired geometric variables." J Biomech. 2012;45(9):1632-7.
Auer PL, Johnsen JM, Johnson AD, et al. "Imputation of exome sequence variants into population- based samples and blood-cell-trait-associated loci in African Americans: NHLBI GO Exome Sequencing Project." Am J Hum Genet. 2012;91(5):794-808.
Maynard JW, McAdams DeMarco MA, Baer AN, et al. "Incident gout in women and association with obesity in the Atherosclerosis Risk in Communities (ARIC) Study." Am J Med. 2012;125(7):717.e9-717.e17.
Hartz SM, Short SE, Saccone NL, et al. "Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers." Arch Gen Psychiatry. 2012;69(8):854-60.
Campos M, Buchanan A, Yu F, et al. "Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study." Blood. 2012;119(8):1929-34.
Chasman DI, Fuchsberger C, Pattaro C, et al. "Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function." Hum Mol Genet. 2012;21(24):5329-43.
Ma L, Brautbar A, Boerwinkle E, Sing CF, Clark AG, Keinan A. "Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations." PLoS Genet. 2012;8(5):e1002714.
Scott RA, Lagou V, Welch RP, et al. "Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways." Nat Genet. 2012;44(9):991-1005.
Morris AP, Voight BF, Teslovich TM, et al. "Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes." Nat Genet. 2012;44(9):981-90.
Asselbergs FW, Guo Y, van Iperen EPA, et al. "Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci." Am J Hum Genet. 2012;91(5):823-38.
Aggarwal V, Schneider ALC, Selvin E. "Low hemoglobin A(1c) in nondiabetic adults: an elevated risk state?" Diabetes Care. 2012;35(10):2055-60.
Stolk L, Perry JRB, Chasman DI, et al. "Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways." Nat Genet. 2012;44(3):260-8.
Qayyum R, Snively BM, Ziv E, et al. "A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans." PLoS Genet. 2012;8(3):e1002491.
Ellinor PT, Lunetta KL, Albert CM, et al. "Meta-analysis identifies six new susceptibility loci for atrial fibrillation." Nat Genet. 2012;44(6):670-5.
Musunuru K, Romaine SPR, Lettre G, et al. "Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project." PLoS One. 2012;7(5):e36473.
Rose KM, Foraker RE, Heiss G, Rosamond WD, Suchindran CM, Whitsel EA. "Neighborhood socioeconomic and racial disparities in angiography and coronary revascularization: the ARIC surveillance study." Ann Epidemiol. 2012;22(9):623-9.
Bhavsar NA, Köttgen A, Coresh J, Astor BC. "Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule 1 (KIM-1) as predictors of incident CKD stage 3: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2012;60(2):233-40.