ARIC Publications
Common variants in the GDF5-UQCC region are associated with variation in human height." Nat Genet. 2008;40(2):198-203.
"Prehypertension is Associated With Abnormalities of Cardiac Structure and Function in the Atherosclerosis Risk in Communities Study." Am J Hypertens. 2016;29(5):568-74.
"Prognostic Importance of Dyspnea for Cardiovascular Outcomes and Mortality in Persons without Prevalent Cardiopulmonary Disease: The Atherosclerosis Risk in Communities Study." PLoS One. 2016;11(10):e0165111.
"Cerebral small vessel disease genomics and its implications across the lifespan." Nat Commun. 2020;11(1):6285.
"Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program." Am J Hum Genet. 2019;105(4):706-718.
"Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche." Hum Reprod. 2021;36(7):1999-2010.
"Whole genome sequence analyses of brain imaging measures in the Framingham Study." Neurology. 2018;90(3):e188-e196.
"Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels." Commun Biol. 2022;5(1):336.
"Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program." PLoS One. 2021;16(7):e0253611.
"Genetic architecture of subcortical brain structures in 38,851 individuals." Nat Genet. 2019;51(11):1624-1636.
"Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study." Circulation. 2011;123(13):1367-76.
"A Comparison of Self-reported Medication Adherence to Concordance Between Part D Claims and Medication Possession." Med Care. 2017;55(5):500-505.
"Mind the Gap: Hospitalizations from Multiple Sources in a Longitudinal Study." Value Health. 2017;20(6):777-784.
"From Neighborhood to Genome: Three Decades of Nutrition-Related Research from the Atherosclerosis Risk in Communities Study." J Acad Nutr Diet. 2017;117(12):1881-1886.e10.
"Asthma and incident cardiovascular disease: the Atherosclerosis Risk in Communities Study." Thorax. 2005;60(8):633-8.
"Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations." BMC Genet. 2014;15:81.
"Albuminuria and Estimated GFR as Risk Factors for Dementia in Midlife and Older Age: Findings From the ARIC Study." Am J Kidney Dis. 2020;76(6):775-783.
"Association of Kidney Function Measures With Signs of Neurodegeneration and Small Vessel Disease on Brain Magnetic Resonance Imaging: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2022.
"Association of exome sequences with plasma C-reactive protein levels in >9000 participants." Hum Mol Genet. 2015;24(2):559-71.
"Meta-analyses identify DNA methylation associated with kidney function and damage." Nat Commun. 2021;12(1):7174.
"A metabolic syndrome in whites and African-Americans. The Atherosclerosis Risk in Communities baseline study." Diabetes Care. 1996;19(5):414-8.
"Clustering of dyslipidemia, hyperuricemia, diabetes, and hypertension and its association with fasting insulin and central and overall obesity in a general population. Atherosclerosis Risk in Communities Study Investigators." Metabolism. 1996;45(6):699-706.
"Identifying individuals at high risk for diabetes: The Atherosclerosis Risk in Communities study." Diabetes Care. 2005;28(8):2013-8.
"Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study." Lancet. 1999;353(9165):1649-52.
"Leptin and incident type 2 diabetes: risk or protection?" Diabetologia. 2006;49(9):2086-96.
"Detection of undiagnosed diabetes and other hyperglycemia states: the Atherosclerosis Risk in Communities Study." Diabetes Care. 2003;26(5):1338-43.
"Arterial distensibility and physical activity in the ARIC study." Med Sci Sports Exerc. 2001;33(12):2065-71.
"Diabetes and Prediabetes and Risk of Hospitalization: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 2016;39(5):772-9.
"Education and cognitive change over 15 years: the atherosclerosis risk in communities study." J Am Geriatr Soc. 2012;60(10):1847-53.
"Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study." Alzheimer Dis Assoc Disord. 2015;29(1):32-44.
"Liver enzymes, race, gender and diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study." Diabet Med. 2013;30(8):926-33.
"Diabetes, Prediabetes, and Brain Volumes and Subclinical Cerebrovascular Disease on MRI: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." Diabetes Care. 2017;40(11):1514-1521.
"Diabetes and risk of fracture-related hospitalization: the Atherosclerosis Risk in Communities Study." Diabetes Care. 2013;36(5):1153-8.
"Prevalence of Disability Associated With Head Injury With Loss of Consciousness in Adults in the United States: A Population-Based Study." Neurology. 2021;97(2):e124-e135.
"Association of Head Injury With Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Cohort." Neurology. 2022;98(8):e808-e817.
"Serum Vitamin D Concentrations and Cognitive Change Over 20 Years: The Atherosclerosis Risk in Communities Neurocognitive Study." Neuroepidemiology. 2018;51(3-4):131-137.
"Vitamin D and cognitive function and dementia risk in a biracial cohort: the ARIC Brain MRI Study." Eur J Neurol. 2014;21(9):1211-8, e69-70.
"Association of Head Injury with Brain Amyloid Deposition: The ARIC-PET Study." J Neurotrauma. 2019;36(17):2549-2557.
"Hemoglobin, Anemia, and Cognitive Function: The Atherosclerosis Risk in Communities Study." J Gerontol A Biol Sci Med Sci. 2016;71(6):772-9.
"High-sensitivity cardiac troponin T and cognitive function and dementia risk: the atherosclerosis risk in communities study." Eur Heart J. 2014;35(27):1817-24.
"Neural correlates of domain-specific cognitive decline: The ARIC-NCS Study." Neurology. 2019;92(10):e1051-e1063.
"Head injury and 25-year risk of dementia." Alzheimers Dement. 2021.
"Cognition and incident dementia hospitalization: results from the atherosclerosis risk in communities study." Neuroepidemiology. 2013;40(2):117-24.
"Vitamin D, vitamin D binding protein gene polymorphisms, race and risk of incident stroke: the Atherosclerosis Risk in Communities (ARIC) study." Eur J Neurol. 2015;22(8):1220-7.
"Validity and reliability of self-reported diabetes in the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2012;176(8):738-43.
"Associations of Prior Head Injury With Olfaction in Older Adults: Results From the Atherosclerosis Risk in Communities (ARIC) Study." JAMA Otolaryngol Head Neck Surg. 2022;148(9):840-848.
"Hyperhomocyst(e)inemia and hemostatic factors: the atherosclerosis risk in communities study." Ann Epidemiol. 2002;12(4):228-36.
"Lipoprotein(a) as a risk factor for preclinical atherosclerotic disease in a biracial cohort: the Atherosclerosis Risk in Communities (ARIC) Study." Chem Phys Lipids. 1994;67-68:405-10.
"Sex-specific associations of magnetic resonance imaging-derived intra-abdominal and subcutaneous fat areas with conventional anthropometric indices. The Atherosclerosis Risk in Communities Study." Am J Epidemiol. 1996;144(4):335-45.
"Gamma prime (γ') fibrinogen and carotid intima-media thickness: the Atherosclerosis Risk in Communities study." Blood Coagul Fibrinolysis. 2017;28(8):665-669.
"Lipoprotein[a] as a risk factor for preclinical atherosclerosis." Arterioscler Thromb. 1993;13(6):826-33.
"Race and gender differences in the association of Lp(a) with carotid artery wall thickness. The Atherosclerosis Risk in Communities (ARIC) Study." Arterioscler Thromb Vasc Biol. 1996;16(3):471-8.
"Lipoprotein(a) as a correlate of stroke and transient ischemic attack prevalence in a biracial cohort: the ARIC Study. Atherosclerosis Risk in Communities." Ann Epidemiol. 1994;4(5):351-9.
"Lung function and incident coronary heart disease: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2003;158(12):1171-81.
"Impaired lung function and subclinical atherosclerosis. The ARIC Study." Atherosclerosis. 2005;180(2):367-73.
"Hypertension, blood pressure, and heart rate variability: the Atherosclerosis Risk in Communities (ARIC) study." Hypertension. 2003;42(6):1106-11.
"Diabetes, glucose, insulin, and heart rate variability: the Atherosclerosis Risk in Communities (ARIC) study." Diabetes Care. 2005;28(3):668-74.
"Repeatability of heart rate variability measures." J Electrocardiol. 2004;37(3):163-72.
"A genetic risk score for thyroid peroxidase antibodies associates with clinical thyroid disease in community-based populations." J Clin Endocrinol Metab. 2015;100(5):E799-807.
"Thyroid function, reduced kidney function and incident chronic kidney disease in a community-based population: the Atherosclerosis Risk in Communities study." Nephrol Dial Transplant. 2017;32(11):1874-1881.
"Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality." Eur Heart J. 2021;42(18):1742-1756.
"Synergism between smoking and vital exhaustion in the risk of ischemic stroke: evidence from the ARIC study." Ann Epidemiol. 2004;14(6):416-24.
""SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe." Eur Heart J. 2021;42(25):2439-2454.
"SCORE2-OP risk prediction algorithms: estimating incident cardiovascular event risk in older persons in four geographical risk regions." Eur Heart J. 2021;42(25):2455-2467.
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease." Sci Transl Med. 2016;8(341):341ra76.
"An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans." Diabetes. 2017;66(11):2888-2902.
"Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways." Nat Genet. 2012;44(9):991-1005.
"No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels." Diabetes. 2012;61(5):1291-6.
"Migraine and atrial fibrillation: a systematic review." Eur J Neurol. 2022;29(3):910-920.
"Association of von Willebrand factor deficiency with prevalent cardiovascular disease and asymptomatic carotid atherosclerosis: The Atherosclerosis Risk in Communities Study." Thromb Res. 2016;144:236-8.
"Kidney Function, Polypharmacy, and Potentially Inappropriate Medication Use in a Community-Based Cohort of Older Adults." Drugs Aging. 2018;35(8):735-750.
"Machine Learning-Based Models Incorporating Social Determinants of Health vs Traditional Models for Predicting In-Hospital Mortality in Patients With Heart Failure." JAMA Cardiol. 2022;7(8):844-854.
"Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis." Circulation. 2021;143(24):2370-2383.
"Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk." J Am Coll Cardiol. 2018;72(15):1763-1773.
"Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis." Lancet Public Health. 2018;3(9):e419-e428.
"Retinal Vessel Calibers in Predicting Long-Term Cardiovascular Outcomes: The Atherosclerosis Risk in Communities Study." Circulation. 2016;134(18):1328-1338.
"An Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality." J Am Heart Assoc. 2017;6(4).
"Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease." Sci Rep. 2020;10(1):10018.
"Application of Diagnostic Algorithms for Heart Failure With Preserved Ejection Fraction to the Community." JACC Heart Fail. 2020;8(8):640-653.
"Apolipoprotein E Polymorphism, Cardiac Remodeling, and Heart Failure in the ARIC Study." J Card Fail. 2022;28(7):1128-1136.
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