ARIC Publications
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits." Am J Hum Genet. 2019;104(1):112-138.
"Atrial Fibrillation and Brain Magnetic Resonance Imaging Abnormalities." Stroke. 2019;50(4):783-788.
"Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease." Circulation. 2019;140(8):645-657.
"Cancer Survivorship and Subclinical Myocardial Damage." Am J Epidemiol. 2019;188(12):2188-2195.
"Cardio-ankle vascular index and cardiovascular disease: Systematic review and meta-analysis of prospective and cross-sectional studies." J Clin Hypertens (Greenwich). 2019;21(1):16-24.
"Cardiovascular Risk Factors Associated With Venous Thromboembolism." JAMA Cardiol. 2019;4(2):163-173.
"A catalog of genetic loci associated with kidney function from analyses of a million individuals." Nat Genet. 2019;51(6):957-972.
"Central and peripheral pulse wave velocity and subclinical myocardial stress and damage in older adults." PLoS One. 2019;14(2):e0212892.
"Central Arterial Stiffness Is Associated With Structural Brain Damage and Poorer Cognitive Performance: The ARIC Study." J Am Heart Assoc. 2019;8(2):e011045.
"Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies." Lancet Diabetes Endocrinol. 2019;7(2):115-127.
"Cigarette Smoking, Smoking Cessation, and Long-Term Risk of 3 Major Atherosclerotic Diseases." J Am Coll Cardiol. 2019;74(4):498-507.
"Circulating ceruloplasmin, ceruloplasmin-associated genes and the incidence of venous thromboembolism in the Atherosclerosis Risk in Communities study." J Thromb Haemost. 2019;17(5):818-826.
"Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals." Circ Res. 2019;125(8):773-782.
"Coffee consumption and liver-related hospitalizations and deaths in the ARIC study." Eur J Clin Nutr. 2019;73(8):1133-1140.
"Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life." J Alzheimers Dis. 2019;68(2):517-521.
"A Collaborative Analysis of Individual Participant Data from 19 Prospective Studies Assesses Circulating Vitamin D and Prostate Cancer Risk." Cancer Res. 2019;79(1):274-285.
"Combined linkage and association analysis identifies rare and low frequency variants for blood pressure at 1q31." Eur J Hum Genet. 2019;27(2):269-277.
"Comparing different definitions of prediabetes with subsequent risk of diabetes: an individual participant data meta-analysis involving 76 513 individuals and 8208 cases of incident diabetes." BMJ Open Diabetes Res Care. 2019;7(1):e000794.
"Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking." Epigenomics. 2019;11(13):1487-1500.
"The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies." Am J Epidemiol. 2019;188(6):991-1012.
"Cost-effectiveness of Pneumococcal Vaccination Among Patients With CKD in the United States." Am J Kidney Dis. 2019;74(1):23-35.
"Dietary choline and betaine intakes and risk of total and lethal prostate cancer in the Atherosclerosis Risk in Communities (ARIC) Study." Cancer Causes Control. 2019;30(4):343-354.
"Dietary patterns and risk of incident chronic kidney disease: the Atherosclerosis Risk in Communities study." Am J Clin Nutr. 2019;110(3):713-721.
"Differences in Cardiovascular Mortality Risk among African Americans in the Minnesota Heart Survey: 1985-2015 vs The Atherosclerosis Risk in Communities Study Cohort: 1987-2015." Ethn Dis. 2019;29(1):47-52.
"Discriminative Accuracy of FEV1:FVC Thresholds for COPD-Related Hospitalization and Mortality." JAMA. 2019;321(24):2438-2447.
"Dynamic predictive accuracy of electrocardiographic biomarkers of sudden cardiac death within a survival framework: the Atherosclerosis Risk in Communities (ARIC) study." BMC Cardiovasc Disord. 2019;19(1):255.
"Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole-Genome Sequencing Studies." Am J Hum Genet. 2019;104(5):802-814.
"Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death." J Am Heart Assoc. 2019;8(23):e013751.
"Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies." Am J Hum Genet. 2019;104(2):260-274.
"Epigenetic Loci of Blood Pressure." Circ Genom Precis Med. 2019;12(1):e002341.
"Estimating the association between blood pressure variability and cardiovascular disease: An application using the ARIC Study." Stat Med. 2019;38(10):1855-1868.
"Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls." Nature. 2019;570(7759):71-76.
"Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology." Am J Hum Genet. 2019;105(1):15-28.
"Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample." Hum Mol Genet. 2019;28(7):1212-1224.
"The Future of Genomic Studies Must Be Globally Representative: Perspectives from PAGE." Annu Rev Genomics Hum Genet. 2019;20:181-200.
"Genetic analyses of diverse populations improves discovery for complex traits." Nature. 2019;570(7762):514-518.
"Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting." Neurology. 2019.
"Genetic architecture of subcortical brain structures in 38,851 individuals." Nat Genet. 2019;51(11):1624-1636.
"Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations." Nat Genet. 2019;51(3):494-505.
"Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing." Nat Genet. 2019;51(3):414-430.
"Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study." Front Genet. 2019;10:494.
"Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data." Nat Commun. 2019;10(1):2773.
"Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria." Nat Commun. 2019;10(1):4130.
"Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits." Eur J Hum Genet. 2019;27(6):952-962.
"A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology." Blood. 2019;133(9):967-977.
"Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans." Hum Genomics. 2019;13(1):21.
"Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group." Am J Hypertens. 2019;32(12):1146-1153.
"Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels." Circulation. 2019;139(5):620-635.
"Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease." Nat Commun. 2019;10(1):4267.
"Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium." Mol Psychiatry. 2019;24(12):1920-1932.
"Genome-wide meta-analysis of SNP-by9-ACEI/ARB and SNP-by-thiazide diuretic and effect on serum potassium in cohorts of European and African ancestry." Pharmacogenomics J. 2019;19(1):97-108.
"Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism." Blood. 2019;134(19):1645-1657.
"Greater Adherence to Life's Simple 7 Is Associated With Less Arterial Stiffness: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2019;32(8):769-776.
"Hearing loss and satisfaction with healthcare: An unexplored relationship." J Am Geriatr Soc. 2019;67(3):624-626.
"Hearing Loss, Hearing Aid Use and Depressive Symptoms in Older Adults - Findings from the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS)." J Gerontol B Psychol Sci Soc Sci. 2019.
"Heritability analysis of nontraditional glycemic biomarkers in the Atherosclerosis Risk in Communities Study." Genet Epidemiol. 2019;43(7):776-785.
"HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study." Hypertension. 2019;73(1):68-74.
"High-Sensitive Troponin T, Natriuretic Peptide, and Cognitive Change." J Am Geriatr Soc. 2019;67(11):2353-2361.
"High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study." Circulation. 2019;139(23):2642-2653.
"Homocysteine and Incident Atrial Fibrillation: The Atherosclerosis Risk in Communities Study and the Multi-Ethnic Study of Atherosclerosis." Heart Lung Circ. 2019;28(4):615-622.
"Hospitalization Risk among Older Adults with Chronic Kidney Disease." Am J Nephrol. 2019;50(3):212-220.
"Hyperglycemia, Classified with Multiple Biomarkers Simultaneously in Men without Diabetes, and Risk of Fatal Prostate Cancer." Cancer Prev Res (Phila). 2019;12(2):103-112.
"Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program." Am J Hum Genet. 2019;105(4):706-718.
"Impaired Lung Function, Lung Disease, and Risk of Incident Dementia." Am J Respir Crit Care Med. 2019;199(11):1385-1396.
"Importance of the heart vector origin point definition for an ECG analysis: The Atherosclerosis Risk in Communities (ARIC) study." Comput Biol Med. 2019;104:127-138.
"Incorporation of Biomarkers Into Risk Assessment for Allocation of Antihypertensive Medication According to the 2017 ACC/AHA High Blood Pressure Guideline: A Pooled Cohort Analysis." Circulation. 2019;140(25):2076-2088.
"In-Hospital and Postdischarge Mortality Among Patients With Acute Decompensated Heart Failure Hospitalizations Ending on the Weekend Versus Weekday: The ARIC Study Community Surveillance." J Am Heart Assoc. 2019;8(15):e011631.
"An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis." Nat Commun. 2019;10(1):2581.
"Joint Associations of Obesity and NT-proBNP With the Incidence of Atrial Fibrillation in the ARIC Study." J Am Heart Assoc. 2019;8(19):e013294.
" Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis." J Am Soc Nephrol. 2019;30(10):2027-2036.
"A large-scale exome array analysis of venous thromboembolism." Genet Epidemiol. 2019;43(4):449-457.
"Leisure-time physical activity sustained since midlife and preservation of cognitive function: The Atherosclerosis Risk in Communities Study." Alzheimers Dement. 2019;15(2):273-281.
"Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data." Hum Genet. 2019;138(2):199-210.
"Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
"Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study." Atherosclerosis. 2019;282:52-56.
"Longitudinal Associations Between Income Changes and Incident Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Cardiol. 2019;4(12):1203-1212.
"Metabolic Syndrome and Risk of Ischemic Stroke in Atrial Fibrillation: ARIC Study." Stroke. 2019;50(11):3045-3050.
"Metabolomic Pattern Predicts Incident Coronary Heart Disease." Arterioscler Thromb Vasc Biol. 2019;39(7):1475-1482.
"Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population." Metabolites. 2019;9(4).
"Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation." Environ Int. 2019;132:104723.
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