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ARIC Publications

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Yu B, Li AH, Metcalf GA, et al. "Loss-of-function variants influence the human serum metabolome." Sci Adv. 2016;2(8):e1600800.
Franceschini N, Muallem H, Rose KM, Boerwinkle E, Maeda N. "Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2009;7(3):496-8.
Zheng Z-jie, Rosamond WD, Chambless LE, et al. "Lower extremity arterial disease assessed by ankle-brachial index in a middle-aged population of African Americans and whites: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Prev Med. 2005;29(5 Suppl 1):42-9.
Schroeder EB, Welch V L, Couper D, et al. "Lung function and incident coronary heart disease: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2003;158(12):1171-81.
Sumida K, Kwak L, Grams ME, et al. "Lung Function and Incident Kidney Disease: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2017;70(5):675-685.
Mirabelli MC, Preisser JS, Loehr LR, et al. "Lung function decline over 25 years of follow-up among black and white adults in the ARIC study cohort." Respir Med. 2016;113:57-64.
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Hardy DS, Racette SB. "Macronutrient intake as a mediator with FTO to increase body mass index." J Am Coll Nutr. 2014;33(4):256-66.
Qayyum R, Snively BM, Ziv E, et al. "A meta-analysis and genome-wide association study of platelet count and mean platelet volume in african americans." PLoS Genet. 2012;8(3):e1002491.
Monda KL, Chen GK, Taylor KC, et al. "A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry." Nat Genet. 2013;45(6):690-6.
Carty CL, Keene KL, Cheng Y-C, et al. "Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans." Stroke. 2015;46(8):2063-8.
C Y Ng M, Shriner D, Chen BH, et al. "Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes." PLoS Genet. 2014;10(8):e1004517.
Chen CTL, Liu C-T, Chen GK, et al. "Meta-analysis of loci associated with age at natural menopause in African-American women." Hum Mol Genet. 2014;23(12):3327-42.
Grams ME, Sang Y, Ballew SH, et al. "A Meta-analysis of the Association of Estimated GFR, Albuminuria, Age, Race, and Sex With Acute Kidney Injury." Am J Kidney Dis. 2015;66(4):591-601.
Chamberlain AM, Agarwal SK, Ambrose M, Folsom AR, Soliman EZ, Alonso A. "Metabolic syndrome and incidence of atrial fibrillation among blacks and whites in the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 2010;159(5):850-6.
Ahmed RL, Schmitz KH, Anderson KE, Rosamond WD, Folsom AR. "The metabolic syndrome and risk of incident colorectal cancer." Cancer. 2006;107(1):28-36.
Bradshaw PT, Monda KL. "Metabolic syndrome in healthy obese, overweight, and normal weight individuals: the Atherosclerosis Risk in Communities Study." Obesity (Silver Spring). 2013;21(1):203-9.
Zheng Y, Yu B, Alexander D, Steffen LM, Nettleton JA. "Metabolomic patterns and alcohol consumption in African Americans in the Atherosclerosis Risk in Communities Study." Am J Clin Nutr. 2014;99(6):1470-8.
Bressler J, Yu B, Mosley TH, et al. "Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study." Transl Psychiatry. 2017;7(7):e1173.
Alonso A, Yu B, Qureshi WT, et al. "Metabolomics and Incidence of Atrial Fibrillation in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study." PLoS One. 2015;10(11):e0142610.
Gottesman RF, Schneider ALC, Albert M, et al. "Midlife hypertension and 20-year cognitive change: the atherosclerosis risk in communities neurocognitive study." JAMA Neurol. 2014;71(10):1218-27.
Fashanu OE, Zhao D, Schneider ALC, et al. "Mid-life serum Vitamin D concentrations were associated with incident dementia but not late-life neuropsychological performance in the Atherosclerosis Risk in Communities (ARIC) Study." BMC Neurol. 2019;19(1):244.
Walker KA, Hoogeveen RC, Folsom AR, et al. "Midlife systemic inflammatory markers are associated with late-life brain volume: The ARIC study." Neurology. 2017;89(22):2262-2270.
Rose KM, Carson AP, Sanford CP, et al. "Migraine and other headaches: associations with Rose angina and coronary heart disease." Neurology. 2004;63(12):2233-9.
Rose KM, Wong TY, Carson AP, Couper DJ, Klein R, Sharrett AR. "Migraine and retinal microvascular abnormalities: the Atherosclerosis Risk in Communities Study." Neurology. 2007;68(20):1694-700.
Johnson AM, Rose KM, Elder GH, Chambless LE, Kaufman JS, Heiss G. "Military combat and burden of subclinical atherosclerosis in middle aged men: the ARIC study." Prev Med. 2010;50(5-6):277-81.
Johnson AM, Rose KM, Elder GH, Chambless LE, Kaufman JS, Heiss G. "Military combat and risk of coronary heart disease and ischemic stroke in aging men: The Atherosclerosis Risk in Communities (ARIC) study." Ann Epidemiol. 2010;20(2):143-50.
Petruski-Ivleva N, Kucharska-Newton AMaria, Palta P, et al. "Milk Intake at Midlife and Cognitive Decline over 20 Years. The Atherosclerosis Risk in Communities (ARIC) Study." Nutrients. 2017;9(10).
Musunuru K, Romaine SPR, Lettre G, et al. "Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project." PLoS One. 2012;7(5):e36473.
Jhun M-A, Mendelson M, Wilson R, et al. "A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids." Nat Commun. 2021;12(1):3987.
Arking DE, Khera A, Xing C, et al. "Multiple independent genetic factors at NOS1AP modulate the QT interval in a multi-ethnic population." PLoS One. 2009;4(1):e4333.
Everett CJ, Mainous AG, Koopman RJ, Diaz VA. "Multiple lipid scoring system for prediction of coronary heart disease risk: application to African Americans." J Natl Med Assoc. 2006;98(11):1740-5.
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Morland K, Wing S, Roux ADiez, Poole C. "Neighborhood characteristics associated with the location of food stores and food service places." Am J Prev Med. 2002;22(1):23-9.
Rose KM, Suchindran CM, Foraker RE, et al. "Neighborhood disparities in incident hospitalized myocardial infarction in four U.S. communities: the ARIC surveillance study." Ann Epidemiol. 2009;19(12):867-74.
Diez-Roux AV, Nieto FJ, Muntaner C, et al. "Neighborhood environments and coronary heart disease: a multilevel analysis." Am J Epidemiol. 1997;146(1):48-63.
Borrell LN, Diez Roux AV, Rose K, Catellier D, Clark BL. "Neighbourhood characteristics and mortality in the Atherosclerosis Risk in Communities Study." Int J Epidemiol. 2004;33(2):398-407.
Chatterjee R, Brancati FL, Shafi T, et al. "Non-traditional risk factors are important contributors to the racial disparity in diabetes risk: the atherosclerosis risk in communities study." J Gen Intern Med. 2014;29(2):290-7.
Schneider ALC, Sharrett ARichey, Gottesman RF, et al. "Normative data for 8 neuropsychological tests in older blacks and whites from the atherosclerosis risk in communities (ARIC) study." Alzheimer Dis Assoc Disord. 2015;29(1):32-44.
Chu AY, Coresh J, Arking DE, et al. "NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study." Diabetologia. 2010;53(3):510-6.
Lee CR, North KE, Bray MS, et al. "NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study." Pharmacogenet Genomics. 2006;16(12):891-9.
Butler AM, Yin X, Evans DS, et al. "Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts." Circ Cardiovasc Genet. 2012;5(6):639-46.
Dastani Z, Hivert M-F, Timpson N, et al. "Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals." PLoS Genet. 2012;8(3):e1002607.
Whitman IR, Vittinghoff E, Defilippi CR, et al. "NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure." J Am Heart Assoc. 2019;8(7):e010868.
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Bryant MJ, Stevens J, Truesdale KP, Mosley T, Chambless L. "Obesity and vital exhaustion: analysis of the Atherosclerosis Risk in the Communities study." Obesity (Silver Spring). 2008;16(7):1545-51.
Bidulescu A, Rose KM, Wolf SH, Rosamond WD. "Occupation recorded on certificates of death compared with self-report: the Atherosclerosis Risk in Communities (ARIC) Study." BMC Public Health. 2007;7:229.
Nunez E, Arnett DK, Benjamin EJ, et al. "Optimal threshold value for left ventricular hypertrophy in blacks: the Atherosclerosis Risk in Communities study." Hypertension. 2005;45(1):58-63.
Agarwal SK, Alonso A, Whelton SP, et al. "Orthostatic change in blood pressure and incidence of atrial fibrillation: results from a bi-ethnic population based study." PLoS One. 2013;8(11):e79030.
Rose KM, Couper D, Eigenbrodt ML, Mosley TH, A Sharrett R, Gottesman RF. "Orthostatic hypotension and cognitive function: the Atherosclerosis Risk in Communities Study." Neuroepidemiology. 2010;34(1):1-7.
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Yao L, Folsom AR, Pankow JS, et al. "Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study." J Hypertens. 2016;34(2):196-203.
Reis JP, Selvin E, Pankow JS, Michos ED, Rebholz CM. "Parathyroid hormone is associated with incident diabetes in white, but not black adults: The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Metab. 2016;42(3):162-9.
Tabor HK, Auer PL, Jamal SM, et al. "Pathogenic variants for Mendelian and complex traits in exomes of 6,517 European and African Americans: implications for the return of incidental results." Am J Hum Genet. 2014;95(2):183-93.
Zhao J, Zhu Y, Boerwinkle E. "Pathway analysis with next-generation sequencing data." Eur J Hum Genet. 2015;23(4):507-15.
Shahar E, Folsom AR, Romm FJ, et al. "Patterns of aspirin use in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study." Am Heart J. 1996;131(5):915-22.
Kshirsagar AV, Moss KL, Elter JR, Beck JD, Offenbacher S, Falk RJ. "Periodontal disease is associated with renal insufficiency in the Atherosclerosis Risk In Communities (ARIC) study." Am J Kidney Dis. 2005;45(4):650-7.
Kalbaugh CA, Kucharska-Newton AMaria, Wruck L, et al. "Peripheral Artery Disease Prevalence and Incidence Estimated From Both Outpatient and Inpatient Settings Among Medicare Fee-for-Service Beneficiaries in the Atherosclerosis Risk in Communities (ARIC) Study." J Am Heart Assoc. 2017;6(5).
Pendergrass SA, Buyske S, Jeff JM, et al. "A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans." PLoS One. 2019;14(12):e0226771.
Bell EJ, Lutsey PL, Windham BG. "Physical activity and cardiovascular disease in African Americans in Atherosclerosis Risk in Communities." Med Sci Sports Exerc. 2013;45(5):901-7.
Pereira MA, Folsom AR, McGovern PG, et al. "Physical activity and incident hypertension in black and white adults: the Atherosclerosis Risk in Communities Study." Prev Med. 1999;28(3):304-12.
Dubbert PM, Penman AD, Evenson KR, Reeves RR, Mosley TH. "Physical activity and subclinical MRI cerebral infarcts: the ARIC Study." J Neurol Sci. 2009;284(1-2):135-9.
Prizment AE, Folsom AR, Dreyfus J, et al. "Plasma C-reactive protein, genetic risk score, and risk of common cancers in the Atherosclerosis Risk in Communities study." Cancer Causes Control. 2013;24(12):2077-87.
Chen H, Mosley TH, Alonso A, Huang X. "Plasma urate and Parkinson's disease in the Atherosclerosis Risk in Communities (ARIC) study." Am J Epidemiol. 2009;169(9):1064-9.
Yatsuya H, Folsom AR, Alonso A, Gottesman RF, Rose KM. "Postural changes in blood pressure and incidence of ischemic stroke subtypes: the ARIC study." Hypertension. 2011;57(2):167-73.
West NA, Tingle JV, Simino J, Selvin E, Bressler J. "The PPARG Pro12Ala Polymorphism and 20-year Cognitive Decline: Race and Sex Heterogeneity." Alzheimer Dis Assoc Disord. 2018;32(2):131-136.
Morrison AC, Huang Z, Yu B, et al. "Practical Approaches for Whole-Genome Sequence Analysis of Heart- and Blood-Related Traits." Am J Hum Genet. 2017;100(2):205-215.
Nagarajarao HS, Penman AD, Taylor HA, et al. "The predictive value of left atrial size for incident ischemic stroke and all-cause mortality in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study." Stroke. 2008;39(10):2701-6.
Parrinello CM, Rastegar I, Godino JG, Miedema MD, Matsushita K. "Prevalence of and Racial Disparities in Risk Factor Control in Older Adults With Diabetes: The Atherosclerosis Risk in Communities Study." Diabetes Care. 2015;38(7):1290-8.
Loehr LR, Soliman EZ, Poon AK, et al. "The prevalence of atrial fibrillation on 48-hour ambulatory electrocardiography in African Americans compared to Whites: The Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2019;216:1-8.
Simpson RJ, Cascio WE, Schreiner PJ, Crow RS, Rautaharju PM, Heiss G. "Prevalence of premature ventricular contractions in a population of African American and white men and women: the Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2002;143(3):535-40.
Garaas R, Moss KL, Fisher EL, et al. "Prevalence of visible third molars with caries experience or periodontal pathology in middle-aged and older Americans." J Oral Maxillofac Surg. 2011;69(2):463-70.
Smith JW, O'Neal WT, M Shoemaker B, Chen LYee, Alonso A, S Whalen P. "PR-Interval Components and Atrial Fibrillation Risk (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(3):466-472.
Fox ER, Han H, Taylor HA, et al. "The prognostic value of the mitral diastolic filling velocity ratio for all-cause mortality and cardiovascular morbidity in African Americans: the Atherosclerotic Risks in Communities (ARIC) study." Am Heart J. 2006;152(4):749-55.
Seidelmann SB, Vardeny O, Claggett B, et al. "An Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality." J Am Heart Assoc. 2017;6(4).
Franceschini N, Hu Y, Reiner AP, et al. "Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study." PLoS One. 2014;9(12):e113203.
Folsom AR, Tang W, Roetker NS, Heckbert SR, Cushman M. "Prospective study of circulating factor XI and incident venous thromboembolism: The Longitudinal Investigation of Thromboembolism Etiology (LITE)." Am J Hematol. 2015;90(11):1047-51.
Folsom AR, Szklo M, Stevens J, Liao F, Smith R, Eckfeldt JH. "A prospective study of coronary heart disease in relation to fasting insulin, glucose, and diabetes. The Atherosclerosis Risk in Communities (ARIC) Study." Diabetes Care. 1997;20(6):935-42.
Roetker NS, Pankow JS, Bressler J, Morrison AC. "Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities)." Circ Genom Precis Med. 2018;11(3):e001937.
Folsom AR, Cushman M, Rasmussen-Torvik LJ, Heckbert SR, Tsai MY. "Prospective study of polymorphisms of the protein Z-dependent protease inhibitor and risk of venous thromboembolism." Thromb Haemost. 2007;97(3):493-4.
Folsom AR, Tang W, Roetker NS, et al. "Prospective study of sickle cell trait and venous thromboembolism incidence." J Thromb Haemost. 2015;13(1):2-9.
Charles LE, Burchfiel CM, Andrew ME, Gu JK, Petrini MF. "Pulmonary function and left ventricular mass in African Americans: the Atherosclerosis Risk in Communities (ARIC) study." Echocardiography. 2012;29(2):131-9.

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