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ARIC Publications

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Knopman DS, Penman AD, Catellier DJ, et al. "Vascular risk factors and longitudinal changes on brain MRI: the ARIC study." Neurology. 2011;76(22):1879-85.
Kocarnik JM, Richard M, Graff M, et al. "Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study." Hum Mol Genet. 2018;27(16):2940-2953.
Kohsaka S, Volcik KA, Folsom AR, et al. "Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study." Atherosclerosis. 2008;196(2):926-30.
Koton S, Schneider ALC, Rosamond WD, Shahar E, Sang Y, Gottesman RF. "Stroke incidence and mortality trends in US communities, 1987 to 2011." JAMA. 2014;312(3):259-68.
Köttgen A, Albrecht E, Teumer A, et al. "Genome-wide association analyses identify 18 new loci associated with serum urate concentrations." Nat Genet. 2013;45(2):145-54.
Köttgen A, Hsu CC, Coresh J, et al. "The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults." Am J Kidney Dis. 2008;52(5):868-75.
Krop JS, Coresh J, Chambless LE, et al. "A community-based study of explanatory factors for the excess risk for early renal function decline in blacks vs whites with diabetes: the Atherosclerosis Risk in Communities study." Arch Intern Med. 1999;159(15):1777-83.
Kshirsagar AV, Coresh J, Brancati F, Colindres RE. "Ankle brachial index independently predicts early kidney disease." Ren Fail. 2004;26(4):433-43.
Kshirsagar AV, Moss KL, Elter JR, Beck JD, Offenbacher S, Falk RJ. "Periodontal disease is associated with renal insufficiency in the Atherosclerosis Risk In Communities (ARIC) study." Am J Kidney Dis. 2005;45(4):650-7.
Kubota Y, Heiss G, Maclehose RF, Roetker NS. "Association of Educational Attainment With Lifetime Risk of Cardiovascular Disease: The Atherosclerosis Risk in Communities Study." JAMA Intern Med. 2017;177(8):1165-1172.
Kucharska-Newton AM, Monda KL, Campbell S, et al. "Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study." Atherosclerosis. 2011;216(1):151-6.
Kucharska-Newton AMaria, Williams JE, Chang PP, Stearns SC, Sueta CA, Blecker SB. "Anger proneness, gender, and the risk of heart failure." J Card Fail. 2014;20(12):1020-6.
Kulkarni M, Foraker RE, McNeill AM, et al. "Evaluation of the modified FINDRISC to identify individuals at high risk for diabetes among middle-aged white and black ARIC study participants." Diabetes Obes Metab. 2017;19(9):1260-1266.
Lacy ME, Wellenius GA, Carnethon MR, et al. "Racial Differences in the Performance of Existing Risk Prediction Models for Incident Type 2 Diabetes: The CARDIA Study." Diabetes Care. 2016;39(2):285-91.
Lagou V, Mägi R, Hottenga J-Jan, et al. "Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability." Nat Commun. 2021;12(1):24.
Lalani SR, Liu P, Rosenfeld JA, et al. "Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations." Am J Hum Genet. 2016;98(2):347-57.
Lawani SO, Demerath EW, Norby FL, Soliman EZ, Huxley RR, Rose KM. "Birth weight and the risk of atrial fibrillation in whites and African Americans: the Atherosclerosis Risk In Communities (ARIC) study." BMC Cardiovasc Disord. 2014;14:69.
Lee CD, Folsom AR, Nieto FJ, Chambless LE, Shahar E, Wolfe DA. "White blood cell count and incidence of coronary heart disease and ischemic stroke and mortality from cardiovascular disease in African-American and White men and women: atherosclerosis risk in communities study." Am J Epidemiol. 2001;154(8):758-64.
Lee CR, North KE, Bray MS, et al. "Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study." Hum Mol Genet. 2006;15(10):1640-9.
Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC. "Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study." Clin Pharmacol Ther. 2008;83(1):52-60.
Lee C D, Folsom AR, Pankow JS, Brancati FL. "Cardiovascular events in diabetic and nondiabetic adults with or without history of myocardial infarction." Circulation. 2004;109(7):855-60.
Lee CR, North KE, Bray MS, et al. "NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: the Atherosclerosis Risk in Communities study." Pharmacogenet Genomics. 2006;16(12):891-9.
Li M, Carey J, Cristiano S, et al. "Genome-Wide Association of Copy Number Polymorphisms and Kidney Function." PLoS One. 2017;12(1):e0170815.
Li M, Maruthur NM, Loomis SJ, et al. "Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism." Sci Rep. 2017;7(1):2812.
Li R, Duncan BB, Metcalf PA, et al. "B-mode-detected carotid artery plaque in a general population. Atherosclerosis Risk in Communities (ARIC) Study Investigators." Stroke. 1994;25(12):2377-83.
Li R, Bensen JT, Hutchinson RG, et al. "Family risk score of coronary heart disease (CHD) as a predictor of CHD: the Atherosclerosis Risk in Communities (ARIC) study and the NHLBI family heart study." Genet Epidemiol. 2000;18(3):236-50.
Li J, Agarwal SK, Alonso A, et al. "Airflow obstruction, lung function, and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) study." Circulation. 2014;129(9):971-80.
Liese AD, Mayer-Davis EJ, Chambless LE, et al. "Elevated fasting insulin predicts incident hypertension: the ARIC study. Atherosclerosis Risk in Communities Study Investigators." J Hypertens. 1999;17(8):1169-77.
Liese AD, Mayer-Davis EJ, Tyroler HA, et al. "Development of the multiple metabolic syndrome in the ARIC cohort: joint contribution of insulin, BMI, and WHR. Atherosclerosis risk in communities." Ann Epidemiol. 1997;7(6):407-16.
Liew G, A Sharrett R, Wang J J, et al. "Relative importance of systemic determinants of retinal arteriolar and venular caliber: the atherosclerosis risk in communities study." Arch Ophthalmol. 2008;126(10):1404-10.
Liew G, Shankar A, Wang J J, et al. "Apolipoprotein E gene polymorphisms and retinal vascular signs: the atherosclerosis risk in communities (ARIC) study." Arch Ophthalmol. 2007;125(6):813-8.
Ligthart S, Marzi C, Aslibekyan S, et al. "DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases." Genome Biol. 2016;17(1):255.
Lindström S, Germain M, Crous-Bou M, et al. "Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study." Hum Genet. 2017;136(7):897-902.
Liu C, Marioni RE, Hedman ÅK, et al. "A DNA methylation biomarker of alcohol consumption." Mol Psychiatry. 2018;23(2):422-433.
Liu C-T, C Y Ng M, Rybin D, et al. "Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource." Diabetologia. 2012;55(11):2970-84.
Liu C-T, Raghavan S, Maruthur N, et al. "Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin." Am J Hum Genet. 2016;99(1):56-75.
Liu C-T, Monda KL, Taylor KC, et al. "Genome-wide association of body fat distribution in African ancestry populations suggests new loci." PLoS Genet. 2013;9(8):e1003681.
Loehr LR, Rosamond WD, Chang PP, Folsom AR, Chambless LE. "Heart failure incidence and survival (from the Atherosclerosis Risk in Communities study)." Am J Cardiol. 2008;101(7):1016-22.
Loehr LR, Soliman EZ, Poon AK, et al. "The prevalence of atrial fibrillation on 48-hour ambulatory electrocardiography in African Americans compared to Whites: The Atherosclerosis Risk in Communities (ARIC) study." Am Heart J. 2019;216:1-8.
Loomis SJ, Li M, Maruthur NM, et al. "Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study." Diabetes. 2018;67(8):1684-1696.
Love S-AM, North KE, Zeng D, et al. "Nine-Year Ethanol Intake Trajectories and Their Association With 15-Year Cognitive Decline Among Black and White Adults." Am J Epidemiol. 2020;189(8):788-800.
Lubitz SA, Lunetta KL, Lin H, et al. "Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese." J Am Coll Cardiol. 2014;63(12):1200-1210.
Lubitz SA, Sinner MF, Lunetta KL, et al. "Independent susceptibility markers for atrial fibrillation on chromosome 4q25." Circulation. 2010;122(10):976-84.
Luft VC, Pereira M, Pankow JS, Ballantyne CM, Couper DJ, Heiss G. "Retinol binding protein 4 and incident diabetes--the Atherosclerosis Risk in Communities Study (ARIC Study)." Rev Bras Epidemiol. 2013;16(2):388-97.
Lunetta KL, Day FR, Sulem P, et al. "Rare coding variants and X-linked loci associated with age at menarche." Nat Commun. 2015;6:7756.
Luoto R, Sharrett AR, Schreiner P, Sorlie PD, Arnett D, Ephross S. "Blood pressure and menopausal transition: the Atherosclerosis Risk in Communities study (1987-95)." J Hypertens. 2000;18(1):27-33.
Lusk CM, Dyson G, Clark AG, et al. "Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study." Hum Genet. 2014;133(9):1105-16.
Lutsey PL, Norby FL, Alonso A, Cushman M, Chen LYee, Michos ED. "Atrial fibrillation and venous thromboembolism: evidence of bidirectionality in the Atherosclerosis Risk in Communities Study." J Thromb Haemost. 2018;16(4):670-679.
Lutsey PL, Rasmussen-Torvik LJ, Pankow JS, et al. "Relation of lipid gene scores to longitudinal trends in lipid levels and incidence of abnormal lipid levels among individuals of European ancestry: the Atherosclerosis Risk in Communities (ARIC) study." Circ Cardiovasc Genet. 2012;5(1):73-80.
Ma Y, Tucker KL, Smith CE, et al. "Lipoprotein lipase variants interact with polyunsaturated fatty acids for obesity traits in women: replication in two populations." Nutr Metab Cardiovasc Dis. 2014;24(12):1323-9.
Ma L, Brautbar A, Boerwinkle E, Sing CF, Clark AG. "Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations." PLoS Genet. 2012;8(5):e1002714.
Ma J, Folsom AR, Melnick SL, et al. "Associations of serum and dietary magnesium with cardiovascular disease, hypertension, diabetes, insulin, and carotid arterial wall thickness: the ARIC study. Atherosclerosis Risk in Communities Study." J Clin Epidemiol. 1995;48(7):927-40.
Machado DB, Crow RS, Boland LL, Hannan PJ, Taylor HA, Folsom AR. "Electrocardiographic findings and incident coronary heart disease among participants in the Atherosclerosis Risk in Communities (ARIC) study." Am J Cardiol. 2006;97(8):1176-1181.
Magnani JW, Norby FL, Agarwal SK, Soliman EZ, Chen LYee, Loehr LR. "Racial Differences in Atrial Fibrillation-Related Cardiovascular Disease and Mortality: The Atherosclerosis Risk in Communities (ARIC) Study." JAMA Cardiol. 2016;1(4):433-41.
Mahajan A, Wessel J, Willems SM, et al. "Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes." Nat Genet. 2018;50(4):559-571.
Maheshwari A, Norby FL, Soliman EZ, et al. "Relation of Prolonged P-Wave Duration to Risk of Sudden Cardiac Death in the General Population (from the Atherosclerosis Risk in Communities Study)." Am J Cardiol. 2017;119(9):1302-1306.
Maruthur NM, Li M, Halushka MK, et al. "Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study." PLoS One. 2015;10(6):e0128452.
Matijevic N, Wu KK, Nidkarni N, Heiss G, Folsom AR. "The ARIC carotid MRI study of blood cellular markers: an inverse association of monocyte myeloperoxidase content with peripheral arterial disease." Angiology. 2011;62(3):237-44.
Matsushita K, Mahmoodi BK, Woodward M, et al. "Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate." JAMA. 2012;307(18):1941-51.
Matsushita K, Sang Y, Ning H, et al. "Lifetime Risk of Lower-Extremity Peripheral Artery Disease Defined by Ankle-Brachial Index in the United States." J Am Heart Assoc. 2019;8(18):e012177.
Maxwell TJ, Ballantyne CM, Cheverud JM, Guild CS, Ndumele CE. "APOE modulates the correlation between triglycerides, cholesterol, and CHD through pleiotropy, and gene-by-gene interactions." Genetics. 2013;195(4):1397-405.
Mayeda ER, Haan MN, Neuhaus J, et al. "Type 2 diabetes and cognitive decline over 14 years in middle-aged African Americans and whites: the ARIC Brain MRI Study." Neuroepidemiology. 2014;43(3-4):220-7.
Maynard JW, McAdams-Demarco MA, Law A, Kao L, Gelber AC, Coresh JJ. "Racial differences in gout incidence in a population-based cohort: Atherosclerosis Risk in Communities Study." Am J Epidemiol. 2014;179(5):576-83.
McAdams-Demarco MA, Maynard JW, Baer AN. "Hypertension and the risk of incident gout in a population-based study: the atherosclerosis risk in communities cohort." J Clin Hypertens (Greenwich). 2012;14(10):675-9.
McAdams-Demarco MA, Law A, Maynard JW, Coresh JJ. "Risk factors for incident hyperuricemia during mid-adulthood in African American and white men and women enrolled in the ARIC cohort study." BMC Musculoskelet Disord. 2013;14:347.
McEvoy JW, Chen Y, Halushka MK, et al. "Galectin-3 and Risk of Heart Failure and Death in Blacks and Whites." J Am Heart Assoc. 2016;5(5).
McKibben RA, Zhao D, Lutsey PL, Schneider ALC, Guallar E, Mosley TH. "Factors Associated With Change in 25-Hydroxyvitamin D Levels Over Longitudinal Follow-Up in the ARIC Study." J Clin Endocrinol Metab. 2016;101(1):33-43.
McNeill A M, Rosamond WD, Girman CJ, et al. "The metabolic syndrome and 11-year risk of incident cardiovascular disease in the atherosclerosis risk in communities study." Diabetes Care. 2005;28(2):385-90.
Mellen PB, Bleyer AJ, Erlinger TP, et al. "Serum uric acid predicts incident hypertension in a biethnic cohort: the atherosclerosis risk in communities study." Hypertension. 2006;48(6):1037-42.
Merino J, Dashti HS, Li SX, et al. "Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium." Mol Psychiatry. 2019;24(12):1920-1932.
Merkin S S, Coresh J, Diez Roux AV, Taylor HA, Powe NR. "Area socioeconomic status and progressive CKD: the Atherosclerosis Risk in Communities (ARIC) Study." Am J Kidney Dis. 2005;46(2):203-13.
Metcalf PA, Sharrett AR, Folsom AR, et al. "African American-white differences in lipids, lipoproteins, and apolipoproteins, by educational attainment, among middle-aged adults: the Atherosclerosis Risk in Communities Study." Am J Epidemiol. 1998;148(8):750-60.
Meyer TE, Verwoert GC, Hwang S-J, et al. "Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels." PLoS Genet. 2010;6(8).
Meyer TE, Shiffman D, Morrison AC, et al. "GOSR2 Lys67Arg is associated with hypertension in whites." Am J Hypertens. 2009;22(2):163-8.
Meyer ML, Tanaka H, Palta P, Cheng S, Gouskova N, Aguilar D. "Correlates of Segmental Pulse Wave Velocity in Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study." Am J Hypertens. 2016;29(1):114-22.
Michaud DS, Lu J, Peacock-Villada AY, et al. "Periodontal Disease Assessed Using Clinical Dental Measurements and Cancer Risk in the ARIC Study." J Natl Cancer Inst. 2018;110(8):843-854.
Michos ED, Carson KA, Schneider ALC, et al. "Vitamin D and subclinical cerebrovascular disease: the Atherosclerosis Risk in Communities brain magnetic resonance imaging study." JAMA Neurol. 2014;71(7):863-71.
Michos ED, Misialek JR, Selvin E, Folsom AR, Pankow JS, Post WS. "25-hydroxyvitamin D levels, vitamin D binding protein gene polymorphisms and incident coronary heart disease among whites and blacks: The ARIC study." Atherosclerosis. 2015;241(1):12-7.
Miedema MD, Norby FL, Blaha MJ, Virani SS, Coresh JJ, Ballantyne CM. "Implications of the Eighth Joint National Committee Guidelines for the Management of High Blood Pressure for Aging Adults: Atherosclerosis Risk in Communities Study." Hypertension. 2015;66(3):474-80.
Millen AE, Sahli MW, Nie J, et al. "Adequate vitamin D status is associated with the reduced odds of prevalent diabetic retinopathy in African Americans and Caucasians." Cardiovasc Diabetol. 2016;15(1):128.